Compile Data Set for Download or QSAR
maximum 50k data
Found 35 Enz. Inhib. hit(s) with all data for entry = 3119
LigandPNGBDBM28339((1R,2S)-1-{[4-(4-chlorophenyl)benzene][2-(7H-purin...)
Affinity DataIC50:  71nMAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28337((1R,2S)-1-{[4-(4-chlorophenyl)benzene]({2-[4-(meth...)
Affinity DataIC50:  73nMAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28327((1R,2S)-1-{[4-(4-chlorophenyl)benzene][2-(3-methox...)
Affinity DataIC50:  78nMpH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM28340((1R,2S)-1-{[4-(4-chlorophenyl)benzene][2-(9H-purin...)
Affinity DataIC50:  170nMAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28332((1R,2S)-1-{[4-(4-chlorophenyl)benzene][2-(1H-1,2,4...)
Affinity DataIC50:  180nMAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28326((1R,2S)-1-{[4-(4-chlorophenyl)benzene][2-(2-oxo-1,...)
Affinity DataIC50:  180nMpH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28333((1R,2S)-1-{[4-(4-chlorophenyl)benzene][2-(4H-1,2,4...)
Affinity DataIC50:  190nMAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28314((1R,2S)-1-{[4-(4-chlorophenyl)benzene][2-(2-oxopyr...)
Affinity DataIC50:  200nMpH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28325((1R,2S)-1-{[4-(4-chlorophenyl)benzene][2-(2-oxopip...)
Affinity DataIC50:  210nMpH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28324((1R,2S)-1-{[4-(4-chlorophenyl)benzene][2-(2-oxo-1,...)
Affinity DataIC50:  220nMpH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28338((1R,2S)-1-{[4-(4-chlorophenyl)benzene]({2-[5-(meth...)
Affinity DataIC50:  230nMAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28334((1R,2S)-1-{[4-(4-chlorophenyl)benzene][2-(2H-1,2,3...)
Affinity DataIC50:  260nMAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28336((1R,2S)-1-{[4-(4-chlorophenyl)benzene][2-(1H-1,2,3...)
Affinity DataIC50:  270nMAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28335((1R,2S)-1-{[4-(4-chlorophenyl)benzene][2-(1H-1,2,3...)
Affinity DataIC50:  270nMAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28329((1R,2S)-1-{[4-(4-chlorophenyl)benzene][2-(pyridin-...)
Affinity DataIC50:  290nMAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28323((1R,2S)-1-{[4-(4-chlorophenyl)benzene][2-(2,5-diox...)
Affinity DataIC50:  310nMpH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28331((1R,2S)-1-{[4-(4-chlorophenyl)benzene][2-(1H-imida...)
Affinity DataIC50:  320nMAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28328((1R,2S)-1-{[4-(4-chlorophenyl)benzene][2-(pyridin-...)
Affinity DataIC50:  750nMpH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28330((1R,2S)-1-{[4-(4-chlorophenyl)benzene][2-(pyridin-...)
Affinity DataIC50:  820nMAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28316((1R,2S)-1-({[4-(4-chlorophenyl)-1,2,3,6-tetrahydro...)
Affinity DataIC50:  880nMpH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28317((1R,2S)-1-{[6-(4-chlorophenyl)pyridine-3-][2-(2-ox...)
Affinity DataIC50:  1.10E+3nMpH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28313((2R)-2-{[4-(4-chlorophenyl)benzene][2-(2-oxopyrrol...)
Affinity DataIC50:  1.60E+3nMpH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28306((2R)-2-{[4-(4-chlorophenyl)benzene]sulfonamido}-3-...)
Affinity DataIC50:  3.20E+3nMpH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28319((1R,2S)-1-{[4-(4-acetamidophenyl)benzene][2-(2-oxo...)
Affinity DataIC50:  4.50E+3nMpH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28318((1R,2S)-1-({4-[4-(dimethylamino)phenyl]benzene}[2-...)
Affinity DataIC50:  6.60E+3nMpH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28312((2R)-2-{[4-(4-chlorophenyl)benzene](2-phenylethyl)...)
Affinity DataIC50:  7.30E+3nMpH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28307((2R)-2-{[4-(4-chlorophenyl)benzene](methyl)sulfona...)
Affinity DataIC50:  8.00E+3nMpH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28315((2R)-2-{[4-(4-chlorophenyl)benzene][2-(2-oxopyrrol...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28308((2S)-2-{[4-(4-chlorophenyl)benzene](methyl)sulfona...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28311((2R)-2-{benzyl[4-(4-chlorophenyl)benzene]sulfonami...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28309((2R)-2-{[4-(4-chlorophenyl)benzene](cyclopropylmet...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28310((2R)-2-{[4-(4-chlorophenyl)benzene](cyclohexylmeth...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28322((1R,2S)-1-{[4-(3-methoxyprop-1-yn-1-yl)benzene][2-...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28321((1R,2S)-1-{[4-(3-hydroxyprop-1-yn-1-yl)benzene][2-...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28320((1R,2S)-1-{[2-(2-oxopyrrolidin-1-yl)ethyl][4-(pyri...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed