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Found 20 Enz. Inhib. hit(s) with all data for assayid = 1 entry = 3163
TargetCytochrome P450 26B1(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization

US Patent
LigandPNGBDBM50253810(CHEMBL459505 | N-(4-(2-ethyl-1-(1H-1,2,4-triazol-1...)
Affinity DataIC50:  0.460nMAssay Description:Eighteen compounds were tested as potential inhibitors of CYP26A1 and CYP26B1. The formation of 9-cis-4-OH-RA metabolite was monitored and the percen...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 26B1(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization

US Patent
LigandPNGBDBM393281(US9963439, R116010)
Affinity DataIC50:  3.10nMAssay Description:Eighteen compounds were tested as potential inhibitors of CYP26A1 and CYP26B1. The formation of 9-cis-4-OH-RA metabolite was monitored and the percen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 26A1(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization

US Patent
LigandPNGBDBM393281(US9963439, R116010)
Affinity DataIC50:  4.30nMAssay Description:Eighteen compounds were tested as potential inhibitors of CYP26A1 and CYP26B1. The formation of 9-cis-4-OH-RA metabolite was monitored and the percen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 26A1(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization

US Patent
LigandPNGBDBM50253810(CHEMBL459505 | N-(4-(2-ethyl-1-(1H-1,2,4-triazol-1...)
Affinity DataIC50:  5.10nMAssay Description:Eighteen compounds were tested as potential inhibitors of CYP26A1 and CYP26B1. The formation of 9-cis-4-OH-RA metabolite was monitored and the percen...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 26B1(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization

US Patent
LigandPNGBDBM50157605(Liarozole | Liazal | R-75251 | US9963439, Liarozol...)
Affinity DataIC50:  18nMAssay Description:Eighteen compounds were tested as potential inhibitors of CYP26A1 and CYP26B1. The formation of 9-cis-4-OH-RA metabolite was monitored and the percen...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 26B1(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization

US Patent
LigandPNGBDBM151585(US11739089, Compound Ketoconazole | US8987315, Ket...)
Affinity DataIC50:  140nMAssay Description:Eighteen compounds were tested as potential inhibitors of CYP26A1 and CYP26B1. The formation of 9-cis-4-OH-RA metabolite was monitored and the percen...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 26A1(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization

US Patent
LigandPNGBDBM151585(US11739089, Compound Ketoconazole | US8987315, Ket...)
Affinity DataIC50:  660nMAssay Description:Eighteen compounds were tested as potential inhibitors of CYP26A1 and CYP26B1. The formation of 9-cis-4-OH-RA metabolite was monitored and the percen...More data for this Ligand-Target Pair
In DepthDetails US PatentDrugBank

TargetCytochrome P450 26A1(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization

US Patent
LigandPNGBDBM50157605(Liarozole | Liazal | R-75251 | US9963439, Liarozol...)
Affinity DataIC50:  1.90E+3nMAssay Description:Eighteen compounds were tested as potential inhibitors of CYP26A1 and CYP26B1. The formation of 9-cis-4-OH-RA metabolite was monitored and the percen...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 26A1(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization

US Patent
LigandPNGBDBM50157731(CHEMBL3785511 | US9963439, Compound C)
Affinity DataIC50:  3.25E+3nMAssay Description:Eighteen compounds were tested as potential inhibitors of CYP26A1 and CYP26B1. The formation of 9-cis-4-OH-RA metabolite was monitored and the percen...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 26A1(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization

US Patent
LigandPNGBDBM393287(US9963439, Compound D)
Affinity DataIC50:  3.90E+3nMAssay Description:Eighteen compounds were tested as potential inhibitors of CYP26A1 and CYP26B1. The formation of 9-cis-4-OH-RA metabolite was monitored and the percen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 26A1(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization

US Patent
LigandPNGBDBM50157724(CHEMBL3787564 | US9963439, Compound B)
Affinity DataIC50:  4.40E+3nMAssay Description:Eighteen compounds were tested as potential inhibitors of CYP26A1 and CYP26B1. The formation of 9-cis-4-OH-RA metabolite was monitored and the percen...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 26A1(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization

US Patent
LigandPNGBDBM50032219((E)-4-(2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydrona...)
Affinity DataIC50:  5.60E+3nMAssay Description:Eighteen compounds were tested as potential inhibitors of CYP26A1 and CYP26B1. The formation of 9-cis-4-OH-RA metabolite was monitored and the percen...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 26A1(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization

US Patent
LigandPNGBDBM50052414(4-(1,1,4,4-tetramethyl-1,2,3,4-tetrahydronaphthale...)
Affinity DataIC50:  6.50E+3nMAssay Description:Eighteen compounds were tested as potential inhibitors of CYP26A1 and CYP26B1. The formation of 9-cis-4-OH-RA metabolite was monitored and the percen...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 26A1(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization

US Patent
LigandPNGBDBM393290(DDBEP | US9963439, Tazarotenic acid)
Affinity DataIC50:  7.60E+3nMAssay Description:Eighteen compounds were tested as potential inhibitors of CYP26A1 and CYP26B1. The formation of 9-cis-4-OH-RA metabolite was monitored and the percen...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 26A1(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization

US Patent
LigandPNGBDBM393295(US9963439, Compound F)
Affinity DataIC50:  9.90E+3nMAssay Description:Eighteen compounds were tested as potential inhibitors of CYP26A1 and CYP26B1. The formation of 9-cis-4-OH-RA metabolite was monitored and the percen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 26A1(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization

US Patent
LigandPNGBDBM50265920(4-((5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthal...)
Affinity DataIC50:  1.05E+4nMAssay Description:Eighteen compounds were tested as potential inhibitors of CYP26A1 and CYP26B1. The formation of 9-cis-4-OH-RA metabolite was monitored and the percen...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 26A1(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization

US Patent
LigandPNGBDBM50061625(4-[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthal...)
Affinity DataIC50:  1.31E+4nMAssay Description:Eighteen compounds were tested as potential inhibitors of CYP26A1 and CYP26B1. The formation of 9-cis-4-OH-RA metabolite was monitored and the percen...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 26A1(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization

US Patent
LigandPNGBDBM393289(US9963439, BMS961)
Affinity DataIC50:  1.48E+4nMAssay Description:Eighteen compounds were tested as potential inhibitors of CYP26A1 and CYP26B1. The formation of 9-cis-4-OH-RA metabolite was monitored and the percen...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 26A1(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization

US Patent
LigandPNGBDBM36810(BMS753 | US9963439, BMS753)
Affinity DataIC50:  4.02E+4nMAssay Description:Eighteen compounds were tested as potential inhibitors of CYP26A1 and CYP26B1. The formation of 9-cis-4-OH-RA metabolite was monitored and the percen...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 26A1(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization

US Patent
LigandPNGBDBM393294(US9963439, Compound E)
Affinity DataIC50:  4.25E+4nMAssay Description:Eighteen compounds were tested as potential inhibitors of CYP26A1 and CYP26B1. The formation of 9-cis-4-OH-RA metabolite was monitored and the percen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent