BindingDB PrimarySearch

Found 18 hits Enz. Inhib. hit(s) with all data for assayid = 2 entry = 50035257
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Dipeptidyl peptidase 2 (DPP II) (Homo sapiens (Human))	BDBM50118950 ((3S)-4-oxo-4-piperidin-1-ylbutane-1,3-diamine \| (S...) Show SMILES NCC[C@H](N)C(=O)N1CCCCC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UIA) Curated by ChEMBL					Assay Description In vitro inhibition of porcine Dipeptidylpeptidase II.				Bioorg Med Chem Lett 12: 2825-8 (2002) Article DOI: 10.1016/s0960-894x(02)00603-0 BindingDB Entry DOI: 10.7270/Q279457M
University of Antwerp (UIA) Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Dipeptidyl peptidase 2 (DPP II) (Homo sapiens (Human))	BDBM50118935 (2-Amino-3-(1H-imidazol-4-yl)-1-piperidin-1-yl-prop...) Show SMILES NC(Cc1cnc[nH]1)C(=O)N1CCCCC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	328	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UIA) Curated by ChEMBL					Assay Description In vitro inhibition of porcine Dipeptidylpeptidase II.				Bioorg Med Chem Lett 12: 2825-8 (2002) Article DOI: 10.1016/s0960-894x(02)00603-0 BindingDB Entry DOI: 10.7270/Q279457M
University of Antwerp (UIA) Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II) (Homo sapiens (Human))	BDBM50118945 (2,5-Diamino-1-piperidin-1-yl-pentan-1-one \| CHEMBL...) Show SMILES NCCCC(N)C(=O)N1CCCCC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UIA) Curated by ChEMBL					Assay Description In vitro inhibition of porcine Dipeptidylpeptidase II.				Bioorg Med Chem Lett 12: 2825-8 (2002) Article DOI: 10.1016/s0960-894x(02)00603-0 BindingDB Entry DOI: 10.7270/Q279457M
University of Antwerp (UIA) Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II) (Homo sapiens (Human))	BDBM50118942 (2-Amino-3-(1H-imidazol-4-yl)-1-pyrrolidin-1-yl-pro...) Show SMILES NC(Cc1cnc[nH]1)C(=O)N1CCCC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UIA) Curated by ChEMBL					Assay Description In vitro inhibition of porcine Dipeptidylpeptidase II.				Bioorg Med Chem Lett 12: 2825-8 (2002) Article DOI: 10.1016/s0960-894x(02)00603-0 BindingDB Entry DOI: 10.7270/Q279457M
University of Antwerp (UIA) Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II) (Homo sapiens (Human))	BDBM50118953 (2,6-Diamino-1-piperidin-1-yl-hexan-1-one \| CHEMBL9...) Show SMILES NCCCCC(N)C(=O)N1CCCCC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UIA) Curated by ChEMBL					Assay Description In vitro inhibition of porcine Dipeptidylpeptidase II.				Bioorg Med Chem Lett 12: 2825-8 (2002) Article DOI: 10.1016/s0960-894x(02)00603-0 BindingDB Entry DOI: 10.7270/Q279457M
University of Antwerp (UIA) Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II) (Homo sapiens (Human))	BDBM50118933 ((S)-2,3-Diamino-1-piperidin-1-yl-propan-1-one \| CH...) Show SMILES NC[C@H](N)C(=O)N1CCCCC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.84E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UIA) Curated by ChEMBL					Assay Description In vitro inhibition of porcine Dipeptidylpeptidase II.				Bioorg Med Chem Lett 12: 2825-8 (2002) Article DOI: 10.1016/s0960-894x(02)00603-0 BindingDB Entry DOI: 10.7270/Q279457M
University of Antwerp (UIA) Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II) (Homo sapiens (Human))	BDBM50118941 (CHEMBL94955 \| [5-Amino-1-(piperidine-1-carbonyl)-p...) Show SMILES NCCCCC(NC(=O)OCc1ccccc1)C(=O)N1CCCCC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UIA) Curated by ChEMBL					Assay Description In vitro inhibition of porcine Dipeptidylpeptidase II.				Bioorg Med Chem Lett 12: 2825-8 (2002) Article DOI: 10.1016/s0960-894x(02)00603-0 BindingDB Entry DOI: 10.7270/Q279457M
University of Antwerp (UIA) Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II) (Homo sapiens (Human))	BDBM50118947 (2,6-Diamino-1-pyrrolidin-1-yl-hexan-1-one \| CHEMBL...) Show SMILES NCCCCC(N)C(=O)N1CCCC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UIA) Curated by ChEMBL					Assay Description In vitro inhibition of porcine Dipeptidylpeptidase II.				Bioorg Med Chem Lett 12: 2825-8 (2002) Article DOI: 10.1016/s0960-894x(02)00603-0 BindingDB Entry DOI: 10.7270/Q279457M
University of Antwerp (UIA) Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II) (Homo sapiens (Human))	BDBM50118938 (2-Cyclohexylamino-1-piperidin-1-yl-propan-1-one \| ...) Show SMILES N[C@@H](CC1CCCCC1)C(=O)N1CCCCC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UIA) Curated by ChEMBL					Assay Description In vitro inhibition of porcine Dipeptidylpeptidase II.				Bioorg Med Chem Lett 12: 2825-8 (2002) Article DOI: 10.1016/s0960-894x(02)00603-0 BindingDB Entry DOI: 10.7270/Q279457M
University of Antwerp (UIA) Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II) (Homo sapiens (Human))	BDBM50118932 ((S)-2-Amino-3-cyclohexyl-1-pyrrolidin-1-yl-propan-...) Show SMILES N[C@@H](CC1CCCCC1)C(=O)N1CCCC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UIA) Curated by ChEMBL					Assay Description In vitro inhibition of porcine Dipeptidylpeptidase II.				Bioorg Med Chem Lett 12: 2825-8 (2002) Article DOI: 10.1016/s0960-894x(02)00603-0 BindingDB Entry DOI: 10.7270/Q279457M
University of Antwerp (UIA) Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II) (Homo sapiens (Human))	BDBM50118936 (2-Amino-3-methyl-1-piperidin-1-yl-pentan-1-one \| 3...) Show SMILES CCC(C)C(N)C(=O)N1CCCCC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UIA) Curated by ChEMBL					Assay Description In vitro inhibition of porcine Dipeptidylpeptidase II.				Bioorg Med Chem Lett 12: 2825-8 (2002) Article DOI: 10.1016/s0960-894x(02)00603-0 BindingDB Entry DOI: 10.7270/Q279457M
University of Antwerp (UIA) Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II) (Homo sapiens (Human))	BDBM50118949 (2-Amino-3-hydroxy-1-pyrrolidin-1-yl-propan-1-one \|...) Show SMILES NC(CO)C(=O)N1CCCC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UIA) Curated by ChEMBL					Assay Description In vitro inhibition of porcine Dipeptidylpeptidase II.				Bioorg Med Chem Lett 12: 2825-8 (2002) Article DOI: 10.1016/s0960-894x(02)00603-0 BindingDB Entry DOI: 10.7270/Q279457M
University of Antwerp (UIA) Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II) (Homo sapiens (Human))	BDBM50118939 (2-Amino-3-phenyl-1-pyrrolidin-1-yl-propan-1-one \| ...) Show SMILES NC(Cc1ccccc1)C(=O)N1CCCC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UIA) Curated by ChEMBL					Assay Description In vitro inhibition of porcine Dipeptidylpeptidase II.				Bioorg Med Chem Lett 12: 2825-8 (2002) Article DOI: 10.1016/s0960-894x(02)00603-0 BindingDB Entry DOI: 10.7270/Q279457M
University of Antwerp (UIA) Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II) (Homo sapiens (Human))	BDBM50118943 ((2S,3S)-2-amino-3-methyl-1-(pyrrolidin-1-yl)pentan...) Show SMILES CC[C@H](C)[C@H](N)C(=O)N1CCCC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UIA) Curated by ChEMBL					Assay Description In vitro inhibition of porcine Dipeptidylpeptidase II.				Bioorg Med Chem Lett 12: 2825-8 (2002) Article DOI: 10.1016/s0960-894x(02)00603-0 BindingDB Entry DOI: 10.7270/Q279457M
University of Antwerp (UIA) Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II) (Homo sapiens (Human))	BDBM50118937 (2-Amino-3-(4-hydroxy-phenyl)-1-pyrrolidin-1-yl-pro...) Show SMILES NC(Cc1ccc(O)cc1)C(=O)N1CCCC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UIA) Curated by ChEMBL					Assay Description In vitro inhibition of porcine Dipeptidylpeptidase II.				Bioorg Med Chem Lett 12: 2825-8 (2002) Article DOI: 10.1016/s0960-894x(02)00603-0 BindingDB Entry DOI: 10.7270/Q279457M
University of Antwerp (UIA) Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II) (Homo sapiens (Human))	BDBM50118948 (3-Amino-4-oxo-4-pyrrolidin-1-yl-butyramide \| CHEMB...) Show SMILES NC(CC(N)=O)C(=O)N1CCCC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.52E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UIA) Curated by ChEMBL					Assay Description In vitro inhibition of porcine Dipeptidylpeptidase II.				Bioorg Med Chem Lett 12: 2825-8 (2002) Article DOI: 10.1016/s0960-894x(02)00603-0 BindingDB Entry DOI: 10.7270/Q279457M
University of Antwerp (UIA) Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II) (Homo sapiens (Human))	BDBM50118954 (CHEMBL328655 \| Pyrrolidin-2-yl-pyrrolidin-1-yl-met...) Show SMILES S=C(C1CCCN1)N1CCCC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UIA) Curated by ChEMBL					Assay Description In vitro inhibition of porcine Dipeptidylpeptidase II.				Bioorg Med Chem Lett 12: 2825-8 (2002) Article DOI: 10.1016/s0960-894x(02)00603-0 BindingDB Entry DOI: 10.7270/Q279457M
University of Antwerp (UIA) Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II) (Homo sapiens (Human))	BDBM50118931 (2-Amino-1-pyrrolidin-1-yl-ethanone \| 2-amino-1-(py...) Show SMILES NCC(=O)N1CCCC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UIA) Curated by ChEMBL					Assay Description In vitro inhibition of porcine Dipeptidylpeptidase II.				Bioorg Med Chem Lett 12: 2825-8 (2002) Article DOI: 10.1016/s0960-894x(02)00603-0 BindingDB Entry DOI: 10.7270/Q279457M
University of Antwerp (UIA) Curated by ChEMBL					More data for this Ligand-Target Pair