Compile Data Set for Download or QSAR
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Found 5 of ph data with Target = 'Dihydroorotase'
TargetDihydroorotase(Escherichia coli)
Texas A&M University

LigandPNGBDBM85254(4,6-dioxo-piperidine-2-carboxylic acid, 3)
Affinity DataKi:  7.60E+7nMpH: 7.0Assay Description:The DHO-catalyzed hydrolysis of dihydrooroate was monitored spectrophotoetrically at 230 and 280 nm using a SPECTRAmax (Molecular Device) plate reade...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotase(Bacillus anthracis (Firmicute))
University Of Illinois At Chicago

LigandPNGBDBM154573(8-(trifluoromethyl)-9H-purin-6-amine (4) | acs.jme...)
Affinity DataIC50: >1.00E+5nMpH: 7.5Assay Description:The fluorogenic substrate used in this study was ubiquitin-AMC (Boston Biochem). All assays were performed in 384-well black plates (Corning) in a to...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotase(Bacillus anthracis (Firmicute))
University Of Illinois At Chicago

LigandPNGBDBM50007789(CHEMBL1173044 | GRL-0667 | N-(2H-1,3-benzodioxol-5...)
Affinity DataIC50: >1.00E+5nMpH: 7.5Assay Description:The fluorogenic substrate used in this study was ubiquitin-AMC (Boston Biochem). All assays were performed in 384-well black plates (Corning) in a to...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotase(Escherichia coli)
Texas A&M University

LigandPNGBDBM85254(4,6-dioxo-piperidine-2-carboxylic acid, 3)
Affinity DataKi:  2.10E+8nMpH: 8.0Assay Description:The DHO-catalyzed hydrolysis of dihydrooroate was monitored spectrophotoetrically at 230 and 280 nm using a SPECTRAmax (Molecular Device) plate reade...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotase(Escherichia coli)
Texas A&M University

LigandPNGBDBM85254(4,6-dioxo-piperidine-2-carboxylic acid, 3)
Affinity DataKi:  4.40E+8nMpH: 9.0Assay Description:The DHO-catalyzed hydrolysis of dihydrooroate was monitored spectrophotoetrically at 230 and 280 nm using a SPECTRAmax (Molecular Device) plate reade...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed