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Found 710 of ph data with Target = 'High affinity nerve growth factor receptor'
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM24694(4-aminopyrazolylpyrimidine analogue, 5 | 5-bromo-4...)
Affinity DataIC50:  270nMpH: 7.4 T: 2°CAssay Description:TrkA kinase activity was determined by measuring the kinase ability to phosphorylate synthetic tyrosine residues within a generic polypeptide substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM24695(2-N-benzyl-5-bromo-4-N-(5-cyclopropyl-1H-pyrazol-3...)
Affinity DataIC50:  750nMpH: 7.4 T: 2°CAssay Description:TrkA kinase activity was determined by measuring the kinase ability to phosphorylate synthetic tyrosine residues within a generic polypeptide substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM24696(4-aminopyrazolylpyrimidine analogue, 10b | 5-bromo...)
Affinity DataIC50:  720nMpH: 7.4 T: 2°CAssay Description:TrkA kinase activity was determined by measuring the kinase ability to phosphorylate synthetic tyrosine residues within a generic polypeptide substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM24697(4-aminopyrazolylpyrimidine analogue, 10c | 5-bromo...)
Affinity DataIC50:  1.17E+3nMpH: 7.4 T: 2°CAssay Description:TrkA kinase activity was determined by measuring the kinase ability to phosphorylate synthetic tyrosine residues within a generic polypeptide substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM24698(4-aminopyrazolylpyrimidine analogue, 10d | 5-bromo...)
Affinity DataIC50:  120nMpH: 7.4 T: 2°CAssay Description:TrkA kinase activity was determined by measuring the kinase ability to phosphorylate synthetic tyrosine residues within a generic polypeptide substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM24699(4-aminopyrazolylpyrimidine analogue, 10e | 5-bromo...)
Affinity DataIC50:  100nMpH: 7.4 T: 2°CAssay Description:TrkA kinase activity was determined by measuring the kinase ability to phosphorylate synthetic tyrosine residues within a generic polypeptide substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM24700(4-aminopyrazolylpyrimidine analogue, 10f | 5-bromo...)
Affinity DataIC50:  360nMpH: 7.4 T: 2°CAssay Description:TrkA kinase activity was determined by measuring the kinase ability to phosphorylate synthetic tyrosine residues within a generic polypeptide substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM24701(4-aminopyrazolylpyrimidine analogue, 10g | 5-bromo...)
Affinity DataIC50:  100nMpH: 7.4 T: 2°CAssay Description:TrkA kinase activity was determined by measuring the kinase ability to phosphorylate synthetic tyrosine residues within a generic polypeptide substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM24702(4-aminopyrazolylpyrimidine analogue, 10h | 5-bromo...)
Affinity DataIC50:  650nMpH: 7.4 T: 2°CAssay Description:TrkA kinase activity was determined by measuring the kinase ability to phosphorylate synthetic tyrosine residues within a generic polypeptide substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM24703((2S)-2-({5-bromo-4-[(5-cyclopropyl-1H-pyrazol-3-yl...)
Affinity DataIC50:  1.90E+3nMpH: 7.4 T: 2°CAssay Description:TrkA kinase activity was determined by measuring the kinase ability to phosphorylate synthetic tyrosine residues within a generic polypeptide substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM24704((2R)-2-({5-bromo-4-[(5-cyclopropyl-1H-pyrazol-3-yl...)
Affinity DataIC50:  120nMpH: 7.4 T: 2°CAssay Description:TrkA kinase activity was determined by measuring the kinase ability to phosphorylate synthetic tyrosine residues within a generic polypeptide substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM24705(4-aminopyrazolylpyrimidine analogue, 10k | 5-bromo...)
Affinity DataIC50:  6nMpH: 7.4 T: 2°CAssay Description:TrkA kinase activity was determined by measuring the kinase ability to phosphorylate synthetic tyrosine residues within a generic polypeptide substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM24706((2R)-2-({5-chloro-4-[(5-cyclopropyl-1H-pyrazol-3-y...)
Affinity DataIC50:  10nMpH: 7.4 T: 2°CAssay Description:TrkA kinase activity was determined by measuring the kinase ability to phosphorylate synthetic tyrosine residues within a generic polypeptide substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM24707((3S)-3-({5-chloro-4-[(5-cyclopropyl-1H-pyrazol-3-y...)
Affinity DataIC50:  13nMpH: 7.4 T: 2°CAssay Description:TrkA kinase activity was determined by measuring the kinase ability to phosphorylate synthetic tyrosine residues within a generic polypeptide substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM24708((3S)-3-({5-chloro-4-[(5-cyclopropyl-1H-pyrazol-3-y...)
Affinity DataIC50:  15nMpH: 7.4 T: 2°CAssay Description:TrkA kinase activity was determined by measuring the kinase ability to phosphorylate synthetic tyrosine residues within a generic polypeptide substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM24898(3-{[(4-chlorophenyl)methyl]sulfanyl}-5-[(methylcar...)
Affinity DataIC50:  7nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM24899(3-{[1-(4-chlorophenyl)ethyl]sulfanyl}-5-[(methylca...)
Affinity DataIC50:  3nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM24900(3-{[1-(4-chlorophenyl)propyl]sulfanyl}-5-[(methylc...)
Affinity DataIC50:  9nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM24901(3-{[(1R)-1-(4-chlorophenyl)propyl]sulfanyl}-5-[(me...)
Affinity DataIC50:  4nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM24902(3-{[(1S)-1-(4-chlorophenyl)propyl]sulfanyl}-5-[(me...)
Affinity DataIC50:  52nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM24903(3-{[1-(4-chlorophenyl)-2-methylpropyl]sulfanyl}-5-...)
Affinity DataIC50:  16nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM24904(3-{[1-(4-chlorophenyl)butyl]sulfanyl}-5-[(methylca...)
Affinity DataIC50:  35nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM24905(3-{[1-(4-chlorophenyl)-2,2,2-trifluoroethyl]sulfan...)
Affinity DataIC50:  110nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM24906(3-{[(4-chlorophenyl)(phenyl)methyl]sulfanyl}-5-[(m...)
Affinity DataIC50:  2.60E+3nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM24907(1-(3-{[(4-chlorophenyl)methyl]sulfanyl}-4-cyano-1,...)
Affinity DataIC50: >5.00E+3nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM24908(5-amino-3-{[(4-chlorophenyl)methyl]sulfanyl}-1,2-t...)
Affinity DataIC50: >5.00E+3nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM24909(3-{[(4-chlorophenyl)methyl]sulfanyl}-5-(pyridin-2-...)
Affinity DataIC50:  33nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM24910(3-{[(4-chlorophenyl)methyl]sulfanyl}-5-(pyridin-3-...)
Affinity DataIC50:  19nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM24911(3-{[1-(4-chlorophenyl)ethyl]sulfanyl}-5-(pyridin-3...)
Affinity DataIC50:  29nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM24912(3-[(cyclohexylmethyl)sulfanyl]-5-(pyridin-3-ylamin...)
Affinity DataIC50:  610nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM24913(3-{[(4-chlorophenyl)methyl]sulfanyl}-5-(pyridin-4-...)
Affinity DataIC50:  45nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM24914(3-{[(2-chlorophenyl)methyl]sulfanyl}-5-(pyridin-4-...)
Affinity DataIC50:  28nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM24915(3-{[(4-chlorophenyl)methyl]sulfanyl}-5-(pyrimidin-...)
Affinity DataIC50:  47nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM24916(3-{[(4-chlorophenyl)methyl]sulfanyl}-5-[(6-methoxy...)
Affinity DataIC50:  179nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM24917(3-{[(4-chlorophenyl)methyl]sulfanyl}-5-[(6-oxo-1,6...)
Affinity DataIC50:  84nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM24918(5-(carbamoylamino)-3-[(5-chloro-2,3-dihydro-1H-ind...)
Affinity DataIC50:  10nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM24919(3-[(5-chloro-2,3-dihydro-1H-inden-1-yl)sulfanyl]-5...)
Affinity DataIC50:  8nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM24920(5-(carbamoylamino)-3-(1,2,3,4-tetrahydronaphthalen...)
Affinity DataIC50:  105nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM24921(5-[(methylcarbamoyl)amino]-3-(1,2,3,4-tetrahydrona...)
Affinity DataIC50:  111nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM24922(5-(carbamoylamino)-3-{6,7,8,9-tetrahydro-5H-benzo[...)
Affinity DataIC50: <1nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM24923(5-(carbamoylamino)-3-[(5R)-6,7,8,9-tetrahydro-5H-b...)
Affinity DataIC50: <1nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM24924(5-(carbamoylamino)-3-[(5S)-6,7,8,9-tetrahydro-5H-b...)
Affinity DataIC50:  91nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM31545(Milciclib | pyrazolo[4,3-h]quinazoline-3-carboxami...)
Affinity DataIC50:  53nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates, followed by quantitation of the phosphorylat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM130909(US10683289, Example Staurosporine | US10927120, Co...)
Affinity DataIC50:  1.41nMpH: 7.5Assay Description:Compounds to be tested were dissolved in 100% DMSO in a range of concentrations from 10-8 to 10-3 M including negative control (DMSO), then diluted w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM130910(US8822500, [4])
Affinity DataIC50:  5.00nMpH: 7.5Assay Description:Compounds to be tested were dissolved in 100% DMSO in a range of concentrations from 10-8 to 10-3 M including negative control (DMSO), then diluted w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM130911(US8822500, [2])
Affinity DataIC50:  12.2nMpH: 7.5Assay Description:Compounds to be tested were dissolved in 100% DMSO in a range of concentrations from 10-8 to 10-3 M including negative control (DMSO), then diluted w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM130912(US8822500, [1])
Affinity DataIC50:  1.14nMpH: 7.5Assay Description:Compounds to be tested were dissolved in 100% DMSO in a range of concentrations from 10-8 to 10-3 M including negative control (DMSO), then diluted w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM130913(US8822500, [28])
Affinity DataIC50:  6.35nMpH: 7.5Assay Description:Compounds to be tested were dissolved in 100% DMSO in a range of concentrations from 10-8 to 10-3 M including negative control (DMSO), then diluted w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM130914(US8822500, [12])
Affinity DataIC50:  20.4nMpH: 7.5Assay Description:Compounds to be tested were dissolved in 100% DMSO in a range of concentrations from 10-8 to 10-3 M including negative control (DMSO), then diluted w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM130915(US8822500, [13])
Affinity DataIC50:  6.36nMpH: 7.5Assay Description:Compounds to be tested were dissolved in 100% DMSO in a range of concentrations from 10-8 to 10-3 M including negative control (DMSO), then diluted w...More data for this Ligand-Target Pair
In DepthDetails US Patent
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