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Found 47 of ph data with Target = 'Trypanothione reductase'
TargetTrypanothione reductase(Trypanosoma cruzi)
Universit£T Heidelberg

Curated by ChEMBL
LigandPNGBDBM50170723(1,1'-Hexamethylene bis(5-(p-chlorophenyl)biguanide...)
Affinity DataKi:  2.00E+3nMpH: 7.5Assay Description:Inhibitory constant against recombinant Trypanosoma cruzi trypanothione reductase was determined photometrically at 25 degree C in TR assay buffer (4...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Universit£T Heidelberg

Curated by ChEMBL
LigandPNGBDBM50170726(4,4'-Bis(4-benzyloxy-3-methoxybenzimidoylamino)dic...)
Affinity DataKi:  2.00E+3nMpH: 7.5Assay Description:Inhibitory constant against recombinant Trypanosoma cruzi trypanothione reductase was determined photometrically at 25 degree C in TR assay buffer (4...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Universit£T Heidelberg

Curated by ChEMBL
LigandPNGBDBM50170727(4,4'-Bis(4-benzyloxy-3-methoxybenzimidoylamino)-di...)
Affinity DataKi:  2.00E+3nMpH: 7.5Assay Description:Inhibitory constant against recombinant Trypanosoma cruzi trypanothione reductase was determined photometrically at 25 degree C in TR assay buffer (4...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Universit£T Heidelberg

Curated by ChEMBL
LigandPNGBDBM50170724(1,8-Bis(4-benzyloxy-3-methoxybenzimidoylamino)octa...)
Affinity DataKi:  5.00E+3nMpH: 7.5Assay Description:Inhibitory constant against recombinant Trypanosoma cruzi trypanothione reductase was determined photometrically at 25 degree C in TR assay buffer (4...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Universit£T Heidelberg

Curated by ChEMBL
LigandPNGBDBM50370594(CHEMBL1794917)
Affinity DataKi:  6.00E+3nMpH: 7.5Assay Description:Competitive inhibitory constant against recombinant Trypanosoma cruzi trypanothione reductase was determined photometrically at 25 degree C in TR ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Universit£T Heidelberg

Curated by ChEMBL
LigandPNGBDBM50170722(4-[2-(4-Nitro-phenyl)-2-oxo-acetylamino]-piperidin...)
Affinity DataKi:  6.20E+3nMpH: 7.5Assay Description:Inhibitory constant against recombinant Trypanosoma cruzi trypanothione reductase was determined photometrically at 25 degree C in TR assay buffer (4...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Universit£T Heidelberg

Curated by ChEMBL
LigandPNGBDBM28349(N-methyl-N-({[2-(phenylsulfanyl)phenyl]carbamoyl}m...)
Affinity DataIC50:  5.63E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Universit£T Heidelberg

Curated by ChEMBL
LigandPNGBDBM28350(2-[(3aR,7aS)-1,3-dioxo-2,3,3a,4,7,7a-hexahydro-1H-...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Universit£T Heidelberg

Curated by ChEMBL
LigandPNGBDBM28351(2-{2,4-dioxo-1,3-diazaspiro[4.6]undecan-3-yl}-N-[2...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Universit£T Heidelberg

Curated by ChEMBL
LigandPNGBDBM28352((1S)-1-(naphthalen-2-ylcarbamoyl)pentane-1,5-bis(a...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Universit£T Heidelberg

Curated by ChEMBL
LigandPNGBDBM28353(1-(4-methylphenyl)-5-oxo-N-[2-(phenylsulfanyl)phen...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Universit£T Heidelberg

Curated by ChEMBL
LigandPNGBDBM28354(2-{6-methyl-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-y...)
Affinity DataIC50:  8.44E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Universit£T Heidelberg

Curated by ChEMBL
LigandPNGBDBM28355((2S)-2-benzenesulfonamido-N-[2-(phenylsulfanyl)phe...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Universit£T Heidelberg

Curated by ChEMBL
LigandPNGBDBM28356((3R)-1-methyl-3-[(10R)-9-oxa-2-thiatricyclo[9.4.0....)
Affinity DataIC50:  1.15E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Universit£T Heidelberg

Curated by ChEMBL
LigandPNGBDBM28357(ZINC00347760, 26 | {3-[(10S)-2,9-dithiatricyclo[9....)
Affinity DataIC50:  3.67E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Universit£T Heidelberg

Curated by ChEMBL
LigandPNGBDBM28358((2R,7S)-18-chloro-3,3-dimethyl-14-thia-3-azatetrac...)
Affinity DataIC50:  7.53E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Universit£T Heidelberg

Curated by ChEMBL
LigandPNGBDBM28359(1-benzyl-4-[(E)-[(1-cyclohexyl-2,4,6-trioxo-1,3-di...)
Affinity DataIC50:  4.52E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Universit£T Heidelberg

Curated by ChEMBL
LigandPNGBDBM28360(4-[(4S)-4-[(3-chlorophenyl)carbamoyl]-6-oxo-1,4,5,...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)
University Of Alberta

LigandPNGBDBM28341((9aR)-2-[3-(2-chloro-10H-phenothiazin-10-yl)-3-oxo...)
Affinity DataIC50:  3.19E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)
University Of Alberta

LigandPNGBDBM28343(4-phenyl-1-({[2-(phenylsulfanyl)phenyl]carbamoyl}m...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)
University Of Alberta

LigandPNGBDBM28344(4-carbamoyl-1-({[2-(phenylsulfanyl)phenyl]carbamoy...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)
University Of Alberta

LigandPNGBDBM28345(1-[2-(2-chloro-10H-phenothiazin-10-yl)-2-oxoethyl]...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)
University Of Alberta

LigandPNGBDBM28346(1-[(9S)-6-chloro-2-thiatricyclo[9.4.0.0^{3,8}]pent...)
Affinity DataIC50:  3.60E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)
University Of Alberta

LigandPNGBDBM28347(3-(10H-phenothiazin-10-ylmethyl)-1-azabicyclo[2.2....)
Affinity DataIC50:  5.43E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)
University Of Alberta

LigandPNGBDBM28348((5R,7S)-3-[(3-bromophenyl)methyl]-5,7-dimethyl-1,3...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)
University Of Alberta

LigandPNGBDBM28349(N-methyl-N-({[2-(phenylsulfanyl)phenyl]carbamoyl}m...)
Affinity DataIC50:  4.69E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)
University Of Alberta

LigandPNGBDBM28350(2-[(3aR,7aS)-1,3-dioxo-2,3,3a,4,7,7a-hexahydro-1H-...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)
University Of Alberta

LigandPNGBDBM28351(2-{2,4-dioxo-1,3-diazaspiro[4.6]undecan-3-yl}-N-[2...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)
University Of Alberta

LigandPNGBDBM28352((1S)-1-(naphthalen-2-ylcarbamoyl)pentane-1,5-bis(a...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Universit£T Heidelberg

Curated by ChEMBL
LigandPNGBDBM28348((5R,7S)-3-[(3-bromophenyl)methyl]-5,7-dimethyl-1,3...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Universit£T Heidelberg

Curated by ChEMBL
LigandPNGBDBM28347(3-(10H-phenothiazin-10-ylmethyl)-1-azabicyclo[2.2....)
Affinity DataIC50:  2.18E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Universit£T Heidelberg

Curated by ChEMBL
LigandPNGBDBM28346(1-[(9S)-6-chloro-2-thiatricyclo[9.4.0.0^{3,8}]pent...)
Affinity DataIC50:  2.91E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Universit£T Heidelberg

Curated by ChEMBL
LigandPNGBDBM28345(1-[2-(2-chloro-10H-phenothiazin-10-yl)-2-oxoethyl]...)
Affinity DataIC50:  7.87E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Universit£T Heidelberg

Curated by ChEMBL
LigandPNGBDBM28344(4-carbamoyl-1-({[2-(phenylsulfanyl)phenyl]carbamoy...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Universit£T Heidelberg

Curated by ChEMBL
LigandPNGBDBM28341((9aR)-2-[3-(2-chloro-10H-phenothiazin-10-yl)-3-oxo...)
Affinity DataIC50:  3.54E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Universit£T Heidelberg

Curated by ChEMBL
LigandPNGBDBM28343(4-phenyl-1-({[2-(phenylsulfanyl)phenyl]carbamoyl}m...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Crithidia fasciculata)
Orstom

LigandPNGBDBM85444(CHEMBL506025 | Isotetrandrine (R,S) | Pheanthine (...)
Affinity DataIC50:  1.22E+5nMpH: 7.8 T: 2°CAssay Description:Crithidia fasciculata trypanothione reductase (cfTR) was purifed from E.coli using the expression system. The activity of the cfTR was observed from...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Crithidia fasciculata)
Orstom

LigandPNGBDBM85444(CHEMBL506025 | Isotetrandrine (R,S) | Pheanthine (...)
Affinity DataIC50:  2.35E+5nMpH: 7.8 T: 2°CAssay Description:Crithidia fasciculata trypanothione reductase (cfTR) was purifed from E.coli using the expression system. The activity of the cfTR was observed from...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Crithidia fasciculata)
Orstom

LigandPNGBDBM85442(Gyrocarpine (S,R))
Affinity DataIC50:  5.80E+4nMpH: 7.8 T: 2°CAssay Description:Crithidia fasciculata trypanothione reductase (cfTR) was purifed from E.coli using the expression system. The activity of the cfTR was observed from...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Crithidia fasciculata)
Orstom

LigandPNGBDBM50241641((+)-Homoaromoline | CHEMBL509855 | Homoaromoline |...)
Affinity DataIC50:  5.50E+4nMpH: 7.8 T: 2°CAssay Description:Crithidia fasciculata trypanothione reductase (cfTR) was purifed from E.coli using the expression system. The activity of the cfTR was observed from...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Crithidia fasciculata)
Orstom

LigandPNGBDBM85440(Lindoldhamine (R,R))
Affinity DataIC50:  2.70E+4nMpH: 7.8 T: 2°CAssay Description:Crithidia fasciculata trypanothione reductase (cfTR) was purifed from E.coli using the expression system. The activity of the cfTR was observed from...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Crithidia fasciculata)
Orstom

LigandPNGBDBM85446(Cycleanine (R,R))
Affinity DataIC50:  3.03E+5nMpH: 7.8 T: 2°CAssay Description:Crithidia fasciculata trypanothione reductase (cfTR) was purifed from E.coli using the expression system. The activity of the cfTR was observed from...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Crithidia fasciculata)
Orstom

LigandPNGBDBM50292467(Antioquine | Antioquine (S,R) | CHEMBL446564 | CHE...)
Affinity DataIC50:  6.00E+4nMpH: 7.8 T: 2°CAssay Description:Crithidia fasciculata trypanothione reductase (cfTR) was purifed from E.coli using the expression system. The activity of the cfTR was observed from...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Crithidia fasciculata)
Orstom

LigandPNGBDBM50242977(CHEMBL500862 | Cepharanthine | cepharantine)
Affinity DataIC50:  1.50E+4nMpH: 7.8 T: 2°CAssay Description:Crithidia fasciculata trypanothione reductase (cfTR) was purifed from E.coli using the expression system. The activity of the cfTR was observed from...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Crithidia fasciculata)
Orstom

LigandPNGBDBM41947((-)-BEBEERINE | MLS000069827 | SMR000058852 | bebe...)
Affinity DataIC50:  6.00E+4nMpH: 7.8 T: 2°CAssay Description:Crithidia fasciculata trypanothione reductase (cfTR) was purifed from E.coli using the expression system. The activity of the cfTR was observed from...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Crithidia fasciculata)
Orstom

LigandPNGBDBM85441(Daphnoline (R,S))
Affinity DataIC50:  5.00E+4nMpH: 7.8 T: 2°CAssay Description:Crithidia fasciculata trypanothione reductase (cfTR) was purifed from E.coli using the expression system. The activity of the cfTR was observed from...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Crithidia fasciculata)
Orstom

LigandPNGBDBM85443(Limacine (R,R))
Affinity DataIC50:  9.00E+4nMpH: 7.8 T: 2°CAssay Description:Crithidia fasciculata trypanothione reductase (cfTR) was purifed from E.coli using the expression system. The activity of the cfTR was observed from...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed