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Compile Data Set for Download or QSAR

Found 3 hits of ec50 data for polymerid = 10421,50001520   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Gamma-aminobutyric acid receptor subunit alpha-1 (GABA(A) alpha-1)


(Rattus norvegicus (Rat))
BDBM24183
PNG
(4-amino-n-[2,3-3H]butyric acid | 4-aminobutanoic a...)
Show SMILES NCCCC(O)=O
Show InChI InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)
UniProtKB/SwissProt

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PC cid
PC sid
PDB
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AffyNet 
Article
PubMed
n/an/an/an/a 1.00E+4n/an/an/an/a



Johannes Gutenberg-UniVersity

Curated by ChEMBL


Assay Description
Activity at rat wild type GABAAalpha1beta2 receptor expressed in Xenopus laevis oocytes at -60 mV by Two-Electrode voltage clamp method


J Med Chem 51: 4430-48 (2008)

More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1 (GABA(A) alpha-1)


(Rattus norvegicus (Rat))
BDBM50273002
PNG
(5-Aminomethyl-3H-[1,3,4]oxadiazol-2-one Hydrochlor...)
Show SMILES NCc1n[nH]c(=O)o1
Show InChI InChI=1S/C3H5N3O2/c4-1-2-5-6-3(7)8-2/h1,4H2,(H,6,7)
UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem
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Article
PubMed
n/an/an/an/a 2.80E+5n/an/an/an/a



Johannes Gutenberg-UniVersity

Curated by ChEMBL


Assay Description
Agonist activity at rat recombinant GABAAalpha1beta3gamma2 receptor expressed in HEK293 cells assessed as normalization of GABA-induced current by wh...


J Med Chem 51: 4430-48 (2008)

More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1 (GABA(A) alpha-1)


(Rattus norvegicus (Rat))
BDBM50273004
PNG
(5-Piperidin-4-yl-3H-[1,3,4]oxadiazol-2-thione Hydr...)
Show SMILES Sc1nnc(o1)C1CCNCC1
Show InChI InChI=1S/C7H11N3OS/c12-7-10-9-6(11-7)5-1-3-8-4-2-5/h5,8H,1-4H2,(H,10,12)
UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/an/an/a 9.50E+6n/an/an/an/a



Johannes Gutenberg-UniVersity

Curated by ChEMBL


Assay Description
Agonist activity at rat wild type GABAAalpha1beta2 receptor expressed in Xenopus laevis oocytes at -60 mV by Two-Electrode voltage clamp method


J Med Chem 51: 4430-48 (2008)

More data for this
Ligand-Target Pair