BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit of ec50 data for polymerid = 3417,3418,5020   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Trypanothione reductase


(Trypanosoma cruzi)
BDBM50313985
PNG
(8-methyl-8-azabicyclo[3.2.1]octan-3-one O-(4-chlor...)
Show SMILES CN1C2CCC1CC(C2)=NOC(c1ccccc1)c1ccc(Cl)cc1
Show InChI InChI=1S/C21H23ClN2O/c1-24-19-11-12-20(24)14-18(13-19)23-25-21(15-5-3-2-4-6-15)16-7-9-17(22)10-8-16/h2-10,19-21H,11-14H2,1H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/an/an/a 3.50E+4n/an/an/an/a



Institute of Medical Research

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma cruzi X10/1 recombinant trypanoythione reductase assessed as increase in absorbance at 410 nm due to the formation of TNB


Bioorg Med Chem Lett 20: 1816-8 (2010)

More data for this
Ligand-Target Pair