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Compile Data Set for Download or QSAR

Found 12 hits of ec50 data for polymerid = 4425,4885   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Methionine aminopeptidase Type 2 (MetAP2)


(Mus musculus (Mouse))
BDBM36590
PNG
(FOS-72)
Show SMILES CO[C@H]1C([C@]2(C)OC2CC=C(C)C)[C@@]2(CO2)CCC1=O
Show InChI InChI=1S/C16H24O4/c1-10(2)5-6-12-15(3,20-12)14-13(18-4)11(17)7-8-16(14)9-19-16/h5,12-14H,6-9H2,1-4H3/t12?,13-,14?,15-,16+/m1/s1
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PubMed
n/an/an/an/a 0.0130n/an/a7.5n/a



Massachusetts Institute of Technology



Assay Description
Proliferation assay using bovine aortic endothelial cell (BAEC) line.


Citation and Details
More data for this
Ligand-Target Pair
Methionine aminopeptidase Type 2 (MetAP2)


(Mus musculus (Mouse))
BDBM36589
PNG
(Ovalicin)
Show SMILES CO[C@@H]1C(=O)CC[C@]2(CO2)[C@@]1(O)[C@]1(C)OC1CC=C(C)C
Show InChI InChI=1S/C16H24O5/c1-10(2)5-6-12-14(3,21-12)16(18)13(19-4)11(17)7-8-15(16)9-20-15/h5,12-13,18H,6-9H2,1-4H3/t12?,13-,14-,15+,16+/m1/s1
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n/an/an/an/a 0.0180n/an/a7.5n/a



Massachusetts Institute of Technology



Assay Description
Proliferation assay using bovine aortic endothelial cell (BAEC) line.


Citation and Details
More data for this
Ligand-Target Pair
Methionine aminopeptidase Type 2 (MetAP2)


(Mus musculus (Mouse))
BDBM36588
PNG
(AGM-1470)
Show SMILES CO[C@@H]1[C@@H](CC[C@]2(CO2)C1[C@]1(C)OC1CC=C(C)C)OC(=O)NC(=O)CCl
Show InChI InChI=1S/C19H28ClNO6/c1-11(2)5-6-13-18(3,27-13)16-15(24-4)12(7-8-19(16)10-25-19)26-17(23)21-14(22)9-20/h5,12-13,15-16H,6-10H2,1-4H3,(H,21,22,23)/t12-,13?,15-,16?,18-,19+/m1/s1
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n/an/an/an/a 0.0370n/an/a7.5n/a



Massachusetts Institute of Technology



Assay Description
Proliferation assay using bovine aortic endothelial cell (BAEC) line.


Citation and Details
More data for this
Ligand-Target Pair
Methionine aminopeptidase Type 2 (MetAP2)


(Mus musculus (Mouse))
BDBM36592
PNG
(FOS-70)
Show SMILES CO[C@@H]1[C@@H](CC[C@]2(CO2)C1[C@]1(C)OC1CC=C(C)C)OC(=O)CCCCl
Show InChI InChI=1S/C20H31ClO5/c1-13(2)7-8-15-19(3,26-15)18-17(23-4)14(9-10-20(18)12-24-20)25-16(22)6-5-11-21/h7,14-15,17-18H,5-6,8-12H2,1-4H3/t14-,15?,17-,18?,19-,20+/m1/s1
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n/an/an/an/a 0.120n/an/a7.5n/a



Massachusetts Institute of Technology



Assay Description
Proliferation assay using bovine aortic endothelial cell (BAEC) line.


Citation and Details
More data for this
Ligand-Target Pair
Methionine aminopeptidase Type 2 (MetAP2)


(Mus musculus (Mouse))
BDBM36597
PNG
(FOS-69)
Show SMILES CO[C@@H]1[C@@H](CC[C@]2(CO2)[C@@]1(O)[C@]1(C)OC1CC=C(C)C)OC(=O)CCCCl
Show InChI InChI=1S/C20H31ClO6/c1-13(2)7-8-15-18(3,27-15)20(23)17(24-4)14(9-10-19(20)12-25-19)26-16(22)6-5-11-21/h7,14-15,17,23H,5-6,8-12H2,1-4H3/t14-,15?,17-,18-,19+,20+/m1/s1
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n/an/an/an/a 0.310n/an/a7.5n/a



Massachusetts Institute of Technology



Assay Description
Proliferation assay using bovine aortic endothelial cell (BAEC) line.


Citation and Details
More data for this
Ligand-Target Pair
Methionine aminopeptidase Type 2 (MetAP2)


(Mus musculus (Mouse))
BDBM36595
PNG
(FOS-68)
Show SMILES CO[C@@H]1[C@@H](CC[C@]2(CO2)[C@@]1(O)[C@]1(C)OC1CC=C(C)C)OC(=O)NC(=O)CCl
Show InChI InChI=1S/C19H28ClNO7/c1-11(2)5-6-13-17(3,28-13)19(24)15(25-4)12(7-8-18(19)10-26-18)27-16(23)21-14(22)9-20/h5,12-13,15,24H,6-10H2,1-4H3,(H,21,22,23)/t12-,13?,15-,17-,18+,19+/m1/s1
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n/an/an/an/a 0.460n/an/a7.5n/a



Massachusetts Institute of Technology



Assay Description
Proliferation assay using bovine aortic endothelial cell (BAEC) line.


Citation and Details
More data for this
Ligand-Target Pair
Methionine aminopeptidase Type 2 (MetAP2)


(Mus musculus (Mouse))
BDBM36596
PNG
(FOS-34)
Show SMILES CO[C@@H]1[C@H](O)CC[C@]2(CO2)[C@@]1(O)[C@]1(C)OC1CC=C(C)C
Show InChI InChI=1S/C16H26O5/c1-10(2)5-6-12-14(3,21-12)16(18)13(19-4)11(17)7-8-15(16)9-20-15/h5,11-13,17-18H,6-9H2,1-4H3/t11-,12?,13-,14-,15+,16+/m1/s1
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n/an/an/an/a 2.20n/an/a7.5n/a



Massachusetts Institute of Technology



Assay Description
Proliferation assay using bovine aortic endothelial cell (BAEC) line.


Citation and Details
More data for this
Ligand-Target Pair
Methionine aminopeptidase Type 2 (MetAP2)


(Mus musculus (Mouse))
BDBM36591
PNG
(FOS-37)
Show SMILES CO[C@@H]1[C@H](O)CC[C@]2(CO2)C1[C@]1(C)OC1CC=C(C)C
Show InChI InChI=1S/C16H26O4/c1-10(2)5-6-12-15(3,20-12)14-13(18-4)11(17)7-8-16(14)9-19-16/h5,11-14,17H,6-9H2,1-4H3/t11-,12?,13-,14?,15-,16+/m1/s1
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n/an/an/an/a 9.5n/an/a7.5n/a



Massachusetts Institute of Technology



Assay Description
Proliferation assay using bovine aortic endothelial cell (BAEC) line.


Citation and Details
More data for this
Ligand-Target Pair
Methionine aminopeptidase Type 2 (MetAP2)


(Mus musculus (Mouse))
BDBM36598
PNG
(FOS-67)
Show SMILES CO[C@@H]1[C@@H](CC[C@](O)(SC)[C@@]1(O)[C@]1(C)OC1CC=C(C)C)OC(=O)NC(=O)CCl
Show InChI InChI=1S/C19H30ClNO7S/c1-11(2)6-7-13-17(3,28-13)19(25)15(26-4)12(8-9-18(19,24)29-5)27-16(23)21-14(22)10-20/h6,12-13,15,24-25H,7-10H2,1-5H3,(H,21,22,23)/t12-,13?,15-,17-,18+,19+/m1/s1
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n/an/an/an/a 40n/an/a7.5n/a



Massachusetts Institute of Technology



Assay Description
Proliferation assay using bovine aortic endothelial cell (BAEC) line.


Citation and Details
More data for this
Ligand-Target Pair
Methionine aminopeptidase Type 2 (MetAP2)


(Mus musculus (Mouse))
BDBM36599
PNG
(FOS-201)
Show SMILES CO[C@@H]1[C@H](O)CC[C@](O)(SC)[C@@]1(O)[C@]1(C)OC1CC=C(C)C
Show InChI InChI=1S/C16H28O5S/c1-10(2)6-7-12-14(3,21-12)16(19)13(20-4)11(17)8-9-15(16,18)22-5/h6,11-13,17-19H,7-9H2,1-5H3/t11-,12?,13-,14-,15+,16+/m1/s1
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n/an/an/an/a 56n/an/a7.5n/a



Massachusetts Institute of Technology



Assay Description
Proliferation assay using bovine aortic endothelial cell (BAEC) line.


Citation and Details
More data for this
Ligand-Target Pair
Methionine aminopeptidase Type 2 (MetAP2)


(Mus musculus (Mouse))
BDBM36593
PNG
(FOS-64)
Show SMILES CO[C@@H]1[C@@H](CC[C@](O)(SC)C1[C@]1(C)OC1CC=C(C)C)OC(=O)NC(=O)CCl
Show InChI InChI=1S/C19H30ClNO6S/c1-11(2)6-7-13-18(3,27-13)16-15(25-4)12(8-9-19(16,24)28-5)26-17(23)21-14(22)10-20/h6,12-13,15-16,24H,7-10H2,1-5H3,(H,21,22,23)/t12-,13?,15-,16?,18-,19+/m1/s1
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n/an/an/an/a 110n/an/a7.5n/a



Massachusetts Institute of Technology



Assay Description
Proliferation assay using bovine aortic endothelial cell (BAEC) line.


Citation and Details
More data for this
Ligand-Target Pair
Methionine aminopeptidase Type 2 (MetAP2)


(Mus musculus (Mouse))
BDBM36594
PNG
(FOS-202)
Show SMILES CO[C@@H]1[C@H](O)CC[C@](O)(SC)C1[C@]1(C)OC1CC=C(C)C
Show InChI InChI=1S/C16H28O4S/c1-10(2)6-7-12-15(3,20-12)14-13(19-4)11(17)8-9-16(14,18)21-5/h6,11-14,17-18H,7-9H2,1-5H3/t11-,12?,13-,14?,15-,16+/m1/s1
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n/an/an/an/a 2.80E+3n/an/a7.5n/a



Massachusetts Institute of Technology



Assay Description
Proliferation assay using bovine aortic endothelial cell (BAEC) line.


Citation and Details
More data for this
Ligand-Target Pair