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Compile Data Set for Download or QSAR

Found 4 hits of ec50 data for polymerid = 49000229,49000231,49000232   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adrenergic receptor alpha-2


(NEONATAL RAT)
BDBM50055832
PNG
((1H-Imidazol-2-yl)-(5-methyl-2,3-dihydro-benzo[1,4...)
Show SMILES Cc1c(Nc2ncc[nH]2)ccc2OCCOc12
Show InChI InChI=1S/C12H13N3O2/c1-8-9(15-12-13-4-5-14-12)2-3-10-11(8)17-7-6-16-10/h2-5H,6-7H2,1H3,(H2,13,14,15)
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PubMed
n/an/an/an/a 41n/an/an/an/a



Allergan Pharmaceuticals

Curated by ChEMBL


Assay Description
Effective Concentration at Alpha-2B adrenergic receptor from CHO-RNG cells


Citation and Details
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(NEONATAL RAT)
BDBM34572
PNG
(BRIMONIDINE | CHEMBL844 | MLS000069370 | SMR000058...)
Show SMILES Brc1c(NC2=NCCN2)ccc2nccnc12
Show InChI InChI=1S/C11H10BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17)
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Similars

AffyNet 
Article
PubMed
n/an/an/an/a 55n/an/an/an/a



Allergan Pharmaceuticals

Curated by ChEMBL


Assay Description
Effective Concentration at Alpha-2B adrenergic receptor from CHO-RNG cells


Citation and Details
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(NEONATAL RAT)
BDBM50055830
PNG
((1H-Imidazol-2-yl)-(5-methyl-3,4-dihydro-2H-benzo[...)
Show SMILES Cc1c(Nc2ncc[nH]2)ccc2OCCNc12
Show InChI InChI=1S/C12H14N4O/c1-8-9(16-12-14-4-5-15-12)2-3-10-11(8)13-6-7-17-10/h2-5,13H,6-7H2,1H3,(H2,14,15,16)
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PubMed
n/an/an/an/a 470n/an/an/an/a



Allergan Pharmaceuticals

Curated by ChEMBL


Assay Description
Effective Concentration at Alpha-2B adrenergic receptor from CHO-RNG cells


Citation and Details
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(NEONATAL RAT)
BDBM50055835
PNG
((4-tert-Butyl-3-methoxy-2,6-dimethyl-phenyl)-(1H-i...)
Show SMILES COc1c(C)c(Nc2ncc[nH]2)c(C)cc1C(C)(C)C
Show InChI InChI=1S/C16H23N3O/c1-10-9-12(16(3,4)5)14(20-6)11(2)13(10)19-15-17-7-8-18-15/h7-9H,1-6H3,(H2,17,18,19)
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PubMed
n/an/an/an/a 1.10E+3n/an/an/an/a



Allergan Pharmaceuticals

Curated by ChEMBL


Assay Description
Effective Concentration at Alpha-2B adrenergic receptor from CHO-RNG cells


Citation and Details
More data for this
Ligand-Target Pair