BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 6 hits of ec50 data for polymerid = 49000355   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cholecystokinin receptor


(RAT)
BDBM50329178
PNG
((S)-3-(3-(1-(2-(isopropyl(phenyl)amino)-2-oxoethyl...)
Show SMILES CC(C)N(C(=O)CN1c2ccccc2N(c2ccccc2)C(=O)[C@@H](NC(=O)Nc2cccc(c2)C(O)=O)C1=O)c1ccccc1
Show InChI InChI=1S/C34H31N5O6/c1-22(2)38(25-14-5-3-6-15-25)29(40)21-37-27-18-9-10-19-28(27)39(26-16-7-4-8-17-26)32(42)30(31(37)41)36-34(45)35-24-13-11-12-23(20-24)33(43)44/h3-20,22,30H,21H2,1-2H3,(H,43,44)(H2,35,36,45)/t30-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 63.8n/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Agonist activity at rat CCK1 receptor expressed in CHO cells assessed as induction of calcium release by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50181434
PNG
((S)-2-{3-[3-(4-Benzoylphenyl)ureido]-2,4-dioxo-5-p...)
Show SMILES COc1ccc(cc1)N(C(C)C)C(=O)CN1c2ccccc2N(c2ccccc2)C(=O)[C@@H](NC(=O)Nc2cccc(c2)C(=O)c2ccccc2)C1=O
Show InChI InChI=1S/C41H37N5O6/c1-27(2)45(32-21-23-33(52-3)24-22-32)36(47)26-44-34-19-10-11-20-35(34)46(31-17-8-5-9-18-31)40(50)37(39(44)49)43-41(51)42-30-16-12-15-29(25-30)38(48)28-13-6-4-7-14-28/h4-25,27,37H,26H2,1-3H3,(H2,42,43,51)/t37-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 150n/an/an/an/a



Mayo Clinic

Curated by ChEMBL


Assay Description
Intrinsic agonistic activity at CCK receptor in SD rat at 1uM expressed in pancreatic acinar cell line


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50329182
PNG
(CHEMBL1269261 | N-benzyl-N-isopropyl-2-(5-oxo-1-ph...)
Show SMILES CC(C)N(Cc1ccccc1)C(=O)CN1c2ccccc2-n2c(nnc2-c2ccccc2)C(Nc2ccccc2)C1=O
Show InChI InChI=1S/C34H32N6O2/c1-24(2)38(22-25-14-6-3-7-15-25)30(41)23-39-28-20-12-13-21-29(28)40-32(26-16-8-4-9-17-26)36-37-33(40)31(34(39)42)35-27-18-10-5-11-19-27/h3-21,24,31,35H,22-23H2,1-2H3
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 294n/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Agonist activity at rat CCK1 receptor expressed in CHO cells assessed as induction of calcium release by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50329181
PNG
(3-(6-(2-(benzyl(isopropyl)amino)-2-oxoethyl)-5-oxo...)
Show SMILES CC(C)N(Cc1ccccc1)C(=O)CN1c2ccccc2-n2c(nnc2-c2ccccc2)C(Nc2cccc(c2)C(O)=O)C1=O
Show InChI InChI=1S/C35H32N6O4/c1-23(2)39(21-24-12-5-3-6-13-24)30(42)22-40-28-18-9-10-19-29(28)41-32(25-14-7-4-8-15-25)37-38-33(41)31(34(40)43)36-27-17-11-16-26(20-27)35(44)45/h3-20,23,31,36H,21-22H2,1-2H3,(H,44,45)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 428n/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Agonist activity at rat CCK1 receptor expressed in CHO cells assessed as induction of calcium release by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50329179
PNG
(2-((4S)-4-((1H-indol-3-yl)methyl)-5-oxo-1-phenyl-4...)
Show SMILES CC(C)N(Cc1ccccc1)C(=O)CN1c2ccccc2-n2c(nnc2-c2ccccc2)[C@H](Cc2c[nH]c3ccccc23)C1=O
Show InChI InChI=1S/C37H34N6O2/c1-25(2)41(23-26-13-5-3-6-14-26)34(44)24-42-32-19-11-12-20-33(32)43-35(27-15-7-4-8-16-27)39-40-36(43)30(37(42)45)21-28-22-38-31-18-10-9-17-29(28)31/h3-20,22,25,30,38H,21,23-24H2,1-2H3/t30-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 446n/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Agonist activity at rat CCK1 receptor expressed in CHO cells assessed as induction of calcium release by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50329185
PNG
(2-(4-(1H-indazol-3-yl)-5-oxo-1-phenyl-4H-benzo[b][...)
Show SMILES CC(C)N(Cc1ccccc1)C(=O)CN1c2ccccc2-n2c(nnc2-c2ccccc2)C(c2n[nH]c3ccccc23)C1=O
Show InChI InChI=1S/C35H31N7O2/c1-23(2)40(21-24-13-5-3-6-14-24)30(43)22-41-28-19-11-12-20-29(28)42-33(25-15-7-4-8-16-25)38-39-34(42)31(35(41)44)32-26-17-9-10-18-27(26)36-37-32/h3-20,23,31H,21-22H2,1-2H3,(H,36,37)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 481n/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Agonist activity at rat CCK1 receptor expressed in CHO cells assessed as induction of calcium release by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair