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Compile Data Set for Download or QSAR

Found 1 hit of ec50 data for polymerid = 4953   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Insulin-like growth factor I receptor


(Homo sapiens (Human))
BDBM50313651
PNG
(7-(3-(azetidin-1-ylmethyl)cyclobutyl)-5-(4-(benzyl...)
Show SMILES Nc1ncnc2n(cc(-c3ccc(OCc4ccccc4)cc3)c12)[C@@H]1C[C@H](CN2CCC2)C1
Show InChI InChI=1S/C27H29N5O/c28-26-25-24(21-7-9-23(10-8-21)33-17-19-5-2-1-3-6-19)16-32(27(25)30-18-29-26)22-13-20(14-22)15-31-11-4-12-31/h1-3,5-10,16,18,20,22H,4,11-15,17H2,(H2,28,29,30)/t20-,22+
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Article
PubMed
n/an/an/an/a 86n/an/an/an/a



Schering-Plough

Curated by ChEMBL


Assay Description
Inhibition of IGF1R in human TC71 cells assessed as inhibition of Akt phosphorylation by Western blot analysis


J Med Chem 53: 1413-37 (2010)

More data for this
Ligand-Target Pair