Compile Data Set for Download or QSAR
maximum 50k data
Found 71 of ec50 data for polymerid = 50001413,50001427
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50085558(CHEMBL402676 | Oligoadenylate analogue)
Affinity DataEC50:  0.130nMAssay Description:Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of poly (U) 3'[32P]p5'C3'pMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50085554(5'-O-MONOPHOSPHORYLADENYLYL(2'->5')ADENYLYL(2'->5'...)
Affinity DataEC50:  0.150nMAssay Description:Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of poly (U) 3'[32P]p5'C3'pMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50085558(CHEMBL402676 | Oligoadenylate analogue)
Affinity DataEC50:  0.200nMAssay Description:Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of [32P]-pC11U2C7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50085554(5'-O-MONOPHOSPHORYLADENYLYL(2'->5')ADENYLYL(2'->5'...)
Affinity DataEC50:  0.200nMAssay Description:Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of [32P]-pC11U2C7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50421415(CHEMBL414948)
Affinity DataEC50:  0.210nMAssay Description:Binding affinity of compound to human recombinant Ribonuclease L was evaluatedMore data for this Ligand-Target Pair
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50085553(CHEMBL214603 | Oligoadenylate analogue)
Affinity DataEC50:  0.240nMAssay Description:Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of poly (U) 3'[32P]p5'C3'pMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50085553(CHEMBL214603 | Oligoadenylate analogue)
Affinity DataEC50:  0.300nMAssay Description:Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of poly (U) 3'[32P]p5'C3'pMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50183267(CHEMBL3817920)
Affinity DataEC50:  0.450nMAssay Description:Induction of recombinant human RNase L activity expressed in Escherichia coli using F-5'-r(C11U2C7)-3' as substrate by polyacrylamide gel electrophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50373177(CHEMBL404038)
Affinity DataEC50:  0.5nMAssay Description:Activation of human recombinant Rnase L assessed as cleavage of FRET RNA probeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50085556(CHEMBL405496 | Oligoadenylate analogue)
Affinity DataEC50:  0.680nMAssay Description:Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of [32P]-pC11U2C7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50085555(CHEMBL384725 | Oligoadenylate analogue)
Affinity DataEC50:  0.700nMAssay Description:Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of [32P]-pC11U2C7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50085556(CHEMBL405496 | Oligoadenylate analogue)
Affinity DataEC50:  0.800nMAssay Description:Compound was tested for its binding ability, by displacement of p(A2'p)3A3'[32p]p5'Cp from recombinant human ribonuclease LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50085555(CHEMBL384725 | Oligoadenylate analogue)
Affinity DataEC50:  0.840nMAssay Description:Compound was tested for its binding ability, by displacement of p(A2'p)3A3'[32p]p5'Cp from recombinant human ribonuclease LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Mus musculus)
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50189859(CHEMBL427600 | {[(2R,3R,4R,5R)-5-(6-amino-9H-purin...)
Affinity DataEC50:  0.900nMAssay Description:Activation of mouse RNase L assessed as ability to cleave 5'-[32P]r(C11U2C7)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Mus musculus)
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50189861(CHEMBL424746 | {[(2R,3R,4R,5R)-5-(6-amino-9H-purin...)
Affinity DataEC50:  1.30nMAssay Description:Activation of mouse RNase L assessed as ability to cleave 5'-[32P]r(C11U2C7)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50309129(CHEMBL601938 | {[(2R,3R,4R,5R)-4-[({[(2R,3R,4R,5R)...)
Affinity DataEC50:  2.30nMAssay Description:Induction of recombinant human RNase L activity expressed in Escherichia coli using F-5'-r(C11U2C7)-3' as substrate by polyacrylamide gel electrophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50183270(CHEMBL3818262)
Affinity DataEC50:  2.40nMAssay Description:Induction of recombinant human RNase L activity expressed in Escherichia coli using F-5'-r(C11U2C7)-3' as substrate by polyacrylamide gel electrophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50309130(CHEMBL591446 | {[(2R,3R,4R,5R)-4-[({[(2R,3R,4R,5R)...)
Affinity DataEC50:  2.5nMAssay Description:Inhibition of human RNaseL ANK domain expressed in Escherichia coli assessed as 5' flurescein-r(C11U2C7)-3' RNA cleavageMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50309129(CHEMBL601938 | {[(2R,3R,4R,5R)-4-[({[(2R,3R,4R,5R)...)
Affinity DataEC50:  2.5nMAssay Description:Inhibition of human RNaseL ANK domain expressed in Escherichia coli assessed as 5' flurescein-r(C11U2C7)-3' RNA cleavageMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50183271(CHEMBL3819183)
Affinity DataEC50:  2.70nMAssay Description:Induction of recombinant human RNase L activity expressed in Escherichia coli using F-5'-r(C11U2C7)-3' as substrate by polyacrylamide gel electrophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Mus musculus)
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50189862(CHEMBL414569 | {[(2R,3R,4R,5R)-5-(6-amino-9H-purin...)
Affinity DataEC50:  3.60nMAssay Description:Activation of mouse RNase L assessed as ability to cleave 5'-[32P]r(C11U2C7)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50085559(CHEMBL410213 | Oligoadenylate analogue)
Affinity DataEC50:  4nMAssay Description:Compound was tested for its binding ability, by displacement of p(A2'p)3A3'[32p]p5'Cp from recombinant human ribonuclease LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50388146(CHEMBL2058766)
Affinity DataEC50:  4.20nMAssay Description:Activation of human RNase L expressed in Escherichia coli BL21 (DE3) cells assessed as RNA cleavage using Cy5-rC11-UU-C7-BHQ2 as substrate by FRET as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50085559(CHEMBL410213 | Oligoadenylate analogue)
Affinity DataEC50:  4.60nMAssay Description:Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of [32P]-pC11U2C7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50438548(CHEMBL2414867)
Affinity DataEC50:  6.10nMAssay Description:Activation of human recombinant RNase L endonuclease activity using 6-FAM-UUA UCA AAU UCU UAU UUG CCC CAU UUU UUU GGU UUA-BHQ-1 as substrate assessed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50388147(CHEMBL2058765)
Affinity DataEC50:  6.5nMAssay Description:Activation of human RNase L expressed in Escherichia coli BL21 (DE3) cells assessed as RNA cleavage using Cy5-rC11-UU-C7-BHQ2 as substrate by FRET as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50152834(2''-5--oligoadenylate derivative | [(2R,3R,4R,5R)-...)
Affinity DataEC50:  9.70nMAssay Description:Inhibition of human RNaseL ANK domain expressed in Escherichia coli assessed as 5' flurescein-r(C11U2C7)-3' RNA cleavageMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50183322(CHEMBL601940)
Affinity DataEC50:  13nMAssay Description:Induction of recombinant human RNase L activity expressed in Escherichia coli using F-5'-r(C11U2C7)-3' as substrate by polyacrylamide gel electrophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50388148(CHEMBL2058764)
Affinity DataEC50:  15nMAssay Description:Activation of human RNase L expressed in Escherichia coli BL21 (DE3) cells assessed as RNA cleavage using Cy5-rC11-UU-C7-BHQ2 as substrate by FRET as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50085557(CHEMBL407239 | Oligoadenylate analogue)
Affinity DataEC50:  16nMAssay Description:Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of poly (U) 3'[32P]p5'C3'pMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50152834(2''-5--oligoadenylate derivative | [(2R,3R,4R,5R)-...)
Affinity DataEC50:  17nMAssay Description:Activation of human RNase L expressed in Escherichia coli BL21 (DE3) cells assessed as RNA cleavage using Cy5-rC11-UU-C7-BHQ2 as substrate by FRET as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50438547(CHEMBL2414866)
Affinity DataEC50:  19nMAssay Description:Activation of human recombinant RNase L endonuclease activity using 6-FAM-UUA UCA AAU UCU UAU UUG CCC CAU UUU UUU GGU UUA-BHQ-1 as substrate assessed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50183269(CHEMBL3818726)
Affinity DataEC50:  20nMAssay Description:Induction of recombinant human RNase L activity expressed in Escherichia coli using F-5'-r(C11U2C7)-3' as substrate by polyacrylamide gel electrophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50085557(CHEMBL407239 | Oligoadenylate analogue)
Affinity DataEC50:  30nMAssay Description:Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of [32P]-pC11U2C7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50309127(CHEMBL601939 | {[(2R,3R,4R,5R)-4-[({[(2R,3R,4R,5R)...)
Affinity DataEC50: >50nMAssay Description:Inhibition of human RNaseL ANK domain expressed in Escherichia coli assessed as 5' flurescein-r(C11U2C7)-3' RNA cleavageMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50309128(CHEMBL591445 | {[(2R,3R,4R,5R)-4-[({[(2R,3S,4R,5R)...)
Affinity DataEC50: >50nMAssay Description:Inhibition of human RNaseL ANK domain expressed in Escherichia coli assessed as 5' flurescein-r(C11U2C7)-3' RNA cleavageMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50388145(CHEMBL2057900)
Affinity DataEC50:  53nMAssay Description:Activation of human RNase L expressed in Escherichia coli BL21 (DE3) cells assessed as RNA cleavage using Cy5-rC11-UU-C7-BHQ2 as substrate by FRET as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50183278(CHEMBL3819262)
Affinity DataEC50:  84nMAssay Description:Induction of recombinant human RNase L activity expressed in Escherichia coli using F-5'-r(C11U2C7)-3' as substrate by polyacrylamide gel electrophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50183268(CHEMBL3818137)
Affinity DataEC50:  134nMAssay Description:Induction of recombinant human RNase L activity expressed in Escherichia coli using F-5'-r(C11U2C7)-3' as substrate by polyacrylamide gel electrophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50388159(CHEMBL2058187)
Affinity DataEC50:  200nMAssay Description:Activation of human RNase L expressed in Escherichia coli BL21 (DE3) cells assessed as RNA cleavage using Cy5-rC11-UU-C7-BHQ2 as substrate by FRET as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50438546(CHEMBL2414865)
Affinity DataEC50:  241nMAssay Description:Activation of human recombinant RNase L endonuclease activity using 6-FAM-UUA UCA AAU UCU UAU UUG CCC CAU UUU UUU GGU UUA-BHQ-1 as substrate assessed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50388151(CHEMBL2058191)
Affinity DataEC50:  300nMAssay Description:Activation of human RNase L expressed in Escherichia coli BL21 (DE3) cells assessed as RNA cleavage using Cy5-rC11-UU-C7-BHQ2 as substrate by FRET as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50388163(CHEMBL2058183)
Affinity DataEC50:  300nMAssay Description:Activation of human RNase L expressed in Escherichia coli BL21 (DE3) cells assessed as RNA cleavage using Cy5-rC11-UU-C7-BHQ2 as substrate by FRET as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50388155(CHEMBL2057902)
Affinity DataEC50:  300nMAssay Description:Activation of human RNase L expressed in Escherichia coli BL21 (DE3) cells assessed as RNA cleavage using Cy5-rC11-UU-C7-BHQ2 as substrate by FRET as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Mus musculus)
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50189860(CHEMBL261902 | {[(2R,3S,4R,5R)-5-(6-amino-9H-purin...)
Affinity DataEC50:  323nMAssay Description:Activation of mouse RNase L assessed as ability to cleave 5'-[32P]r(C11U2C7)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Mus musculus)
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50189858(CHEMBL434553 | {[(2R,3R,4R,5R)-5-(6-amino-9H-purin...)
Affinity DataEC50:  393nMAssay Description:Activation of mouse RNase L assessed as ability to cleave 5'-[32P]r(C11U2C7)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Mus musculus)
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50189863(CHEMBL439290 | {[(2R,3S,4R,5R)-5-(6-amino-9H-purin...)
Affinity DataEC50:  396nMAssay Description:Activation of mouse RNase L assessed as ability to cleave 5'-[32P]r(C11U2C7)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50388149(CHEMBL2058763)
Affinity DataEC50:  1.00E+3nMAssay Description:Activation of human RNase L expressed in Escherichia coli BL21 (DE3) cells assessed as RNA cleavage using Cy5-rC11-UU-C7-BHQ2 as substrate by FRET as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50388150(CHEMBL2058192)
Affinity DataEC50: >1.00E+3nMAssay Description:Activation of human RNase L expressed in Escherichia coli BL21 (DE3) cells assessed as RNA cleavage using Cy5-rC11-UU-C7-BHQ2 as substrate by FRET as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50388152(CHEMBL2058190)
Affinity DataEC50: >1.00E+3nMAssay Description:Activation of human RNase L expressed in Escherichia coli BL21 (DE3) cells assessed as RNA cleavage using Cy5-rC11-UU-C7-BHQ2 as substrate by FRET as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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