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Compile Data Set for Download or QSAR

Found 61 hits of ec50 data for polymerid = 50002104,50002531,6500   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Corticotropin releasing factor receptor 2


(Homo sapiens (Human))
BDBM50087703
PNG
(CHEMBL427807 | Urocortin-human(DNPSLSIDLTFHLLRTLLE...)
Show InChI InChI=1S/C204H337N63O64/c1-28-100(20)154(262-191(323)140(90-271)257-180(312)127(75-96(12)13)247-189(321)138(88-269)259-192(324)141-52-42-70-267(141)199(331)136(83-146(210)279)255-163(295)111(205)81-150(286)287)193(325)254-135(85-152(290)291)185(317)246-129(77-98(16)17)187(319)266-159(107(27)274)198(330)253-131(79-109-45-35-32-36-46-109)181(313)248-132(80-110-86-222-91-228-110)183(315)245-126(74-95(10)11)178(310)243-124(72-93(6)7)176(308)235-116(51-41-69-227-204(220)221)174(306)265-158(106(26)273)197(329)251-128(76-97(14)15)179(311)244-125(73-94(8)9)177(309)239-122(58-64-149(284)285)170(302)242-123(71-92(4)5)175(307)230-104(24)161(293)231-114(49-39-67-225-202(216)217)173(305)264-157(105(25)272)196(328)241-119(55-61-144(208)277)171(303)256-137(87-268)188(320)240-117(53-59-142(206)275)166(298)234-113(48-38-66-224-201(214)215)165(297)238-121(57-63-148(282)283)168(300)233-112(47-37-65-223-200(212)213)164(296)229-103(23)162(294)232-120(56-62-147(280)281)167(299)237-118(54-60-143(207)276)169(301)249-133(82-145(209)278)184(316)236-115(50-40-68-226-203(218)219)172(304)261-156(102(22)30-3)195(327)263-155(101(21)29-2)194(326)252-130(78-108-43-33-31-34-44-108)182(314)250-134(84-151(288)289)186(318)258-139(89-270)190(322)260-153(99(18)19)160(211)292/h31-36,43-46,86,91-107,111-141,153-159,268-274H,28-30,37-42,47-85,87-90,205H2,1-27H3,(H2,206,275)(H2,207,276)(H2,208,277)(H2,209,278)(H2,210,279)(H2,211,292)(H,222,228)(H,229,296)(H,230,307)(H,231,293)(H,232,294)(H,233,300)(H,234,298)(H,235,308)(H,236,316)(H,237,299)(H,238,297)(H,239,309)(H,240,320)(H,241,328)(H,242,302)(H,243,310)(H,244,311)(H,245,315)(H,246,317)(H,247,321)(H,248,313)(H,249,301)(H,250,314)(H,251,329)(H,252,326)(H,253,330)(H,254,325)(H,255,295)(H,256,303)(H,257,312)(H,258,318)(H,259,324)(H,260,322)(H,261,304)(H,262,323)(H,263,327)(H,264,305)(H,265,306)(H,266,319)(H,280,281)(H,282,283)(H,284,285)(H,286,287)(H,288,289)(H,290,291)(H4,212,213,223)(H4,214,215,224)(H4,216,217,225)(H4,218,219,226)(H4,220,221,227)/t100-,101-,102-,103-,104-,105+,106+,107+,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141+,153-,154-,155-,156-,157-,158-,159-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/an/an/a 0.320n/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
Activity of peptidic agonists on h-CRF2-alpha receptor using agonist-stimulated adenylate cyclase assay


J Med Chem 43: 1641-60 (2000)

More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 2


(Homo sapiens (Human))
BDBM50087711
PNG
(CHEMBL429560 | Sauvagine-frog(QGPPISIDLSLELLRKMIEI...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H]1CCCN1C(=O)CNC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)C(N)=O
Show InChI InChI=1S/C202H349N57O63S/c1-29-103(20)156(162(214)284)252-199(321)161(110(27)262)257-191(313)137(92-155(282)283)248-186(308)132(87-101(16)17)244-185(307)131(86-100(14)15)243-183(305)129(84-98(10)11)240-172(294)117(51-43-78-220-202(217)218)229-188(310)135(90-147(213)268)247-189(311)134(89-146(212)267)239-164(286)109(26)222-163(285)108(25)223-166(288)118(55-64-143(209)264)230-173(295)119(56-65-144(210)265)231-167(289)112(46-34-38-73-203)225-175(297)121(58-67-149(270)271)233-169(291)114(48-36-40-75-205)226-176(298)122(59-68-150(272)273)234-174(296)120(57-66-145(211)266)232-168(290)113(47-35-39-74-204)227-177(299)124(61-70-152(276)277)237-195(317)157(104(21)30-2)253-179(301)125(62-71-153(278)279)238-196(318)158(105(22)31-3)254-180(302)126(72-81-323-28)236-170(292)115(49-37-41-76-206)224-171(293)116(50-42-77-219-201(215)216)228-181(303)127(82-96(6)7)242-184(306)130(85-99(12)13)241-178(300)123(60-69-151(274)275)235-182(304)128(83-97(8)9)246-192(314)138(94-260)250-187(309)133(88-102(18)19)245-190(312)136(91-154(280)281)249-197(319)159(106(23)32-4)255-193(315)139(95-261)251-198(320)160(107(24)33-5)256-194(316)140-52-44-80-259(140)200(322)141-53-45-79-258(141)148(269)93-221-165(287)111(207)54-63-142(208)263/h96-141,156-161,260-262H,29-95,203-207H2,1-28H3,(H2,208,263)(H2,209,264)(H2,210,265)(H2,211,266)(H2,212,267)(H2,213,268)(H2,214,284)(H,221,287)(H,222,285)(H,223,288)(H,224,293)(H,225,297)(H,226,298)(H,227,299)(H,228,303)(H,229,310)(H,230,295)(H,231,289)(H,232,290)(H,233,291)(H,234,296)(H,235,304)(H,236,292)(H,237,317)(H,238,318)(H,239,286)(H,240,294)(H,241,300)(H,242,306)(H,243,305)(H,244,307)(H,245,312)(H,246,314)(H,247,311)(H,248,308)(H,249,319)(H,250,309)(H,251,320)(H,252,321)(H,253,301)(H,254,302)(H,255,315)(H,256,316)(H,257,313)(H,270,271)(H,272,273)(H,274,275)(H,276,277)(H,278,279)(H,280,281)(H,282,283)(H4,215,216,219)(H4,217,218,220)/t103-,104-,105-,106-,107-,108-,109-,110+,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141+,156-,157-,158-,159-,160-,161-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/an/an/a 1.40n/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
Activity of peptidic agonists on h-CRF2-alpha receptor using agonist-stimulated adenylate cyclase assay


J Med Chem 43: 1641-60 (2000)

More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 2


(Homo sapiens (Human))
BDBM50087706
PNG
(CHEMBL265847 | Urotensin-1-sucker fish(NDDPPISIDLT...)
Show InChI InChI=1S/C210H340N62O67S2/c1-26-103(17)162(200(333)249-124(58-64-155(288)289)181(314)258-138(86-148(215)278)193(326)244-122(56-62-153(284)285)178(311)239-116(44-35-69-228-206(219)220)175(308)243-121(55-61-152(282)283)179(312)242-120(54-60-146(213)276)172(305)234-107(21)169(302)232-94-151(281)236-130(77-97(5)6)185(318)259-140(88-150(217)280)192(325)241-117(45-36-70-229-207(221)222)174(307)238-115(43-33-34-68-211)176(309)255-135(83-111-50-52-113(275)53-51-111)189(322)252-133(80-100(11)12)188(321)260-141(91-159(296)297)195(328)245-125(59-65-156(290)291)183(316)265-161(102(15)16)168(218)301)266-182(315)119(47-38-72-231-209(225)226)237-170(303)108(22)235-173(306)126(66-75-340-24)246-180(313)123(57-63-154(286)287)248-201(334)163(104(18)27-2)267-184(317)127(67-76-341-25)247-194(327)139(87-149(216)279)257-177(310)118(46-37-71-230-208(223)224)240-186(319)131(78-98(7)8)251-187(320)132(79-99(9)10)253-191(324)137(84-112-93-227-96-233-112)256-190(323)136(82-110-41-31-30-32-42-110)261-204(337)166(109(23)274)270-197(330)134(81-101(13)14)254-196(329)142(92-160(298)299)262-202(335)164(105(19)28-3)268-198(331)143(95-273)263-203(336)165(106(20)29-4)269-199(332)144-48-39-73-271(144)205(338)145-49-40-74-272(145)210(339)264-129(90-158(294)295)167(300)128(89-157(292)293)250-171(304)114(212)85-147(214)277/h30-32,41-42,50-53,93,96-109,114-145,161-166,273-275H,26-29,33-40,43-49,54-92,94-95,211-212H2,1-25H3,(H2,213,276)(H2,214,277)(H2,215,278)(H2,216,279)(H2,217,280)(H2,218,301)(H,227,233)(H,232,302)(H,234,305)(H,235,306)(H,236,281)(H,237,303)(H,238,307)(H,239,311)(H,240,319)(H,241,325)(H,242,312)(H,243,308)(H,244,326)(H,245,328)(H,246,313)(H,247,327)(H,248,334)(H,249,333)(H,250,304)(H,251,320)(H,252,322)(H,253,324)(H,254,329)(H,255,309)(H,256,323)(H,257,310)(H,258,314)(H,259,318)(H,260,321)(H,261,337)(H,262,335)(H,263,336)(H,264,339)(H,265,316)(H,266,315)(H,267,317)(H,268,331)(H,269,332)(H,270,330)(H,282,283)(H,284,285)(H,286,287)(H,288,289)(H,290,291)(H,292,293)(H,294,295)(H,296,297)(H,298,299)(H4,219,220,228)(H4,221,222,229)(H4,223,224,230)(H4,225,226,231)/t103-,104-,105-,106-,107-,108-,109?,114?,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128?,129?,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145+,161-,162-,163-,164-,165?,166-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/an/an/a 1.5n/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
Activity of peptidic agonists on h-CRF2-alpha receptor using agonist-stimulated adenylate cyclase assay


J Med Chem 43: 1641-60 (2000)

More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 2


(Mus musculus)
BDBM50158965
PNG
(CHEMBL437089 | Sauvagine derivative)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H]1CCC(=O)N1)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)C(O)=O
Show InChI InChI=1S/C207H346N56O62S/c1-27-107(18)161(255-183(302)130(67-76-158(280)281)242-199(318)162(108(19)28-2)256-184(303)131(77-87-326-26)240-174(293)119(53-38-42-81-211)228-175(294)120(54-43-82-222-206(218)219)232-185(304)132(88-101(6)7)246-187(306)134(90-103(10)11)245-182(301)126(62-71-150(215)269)239-190(309)137(94-115-48-33-32-34-49-115)251-196(315)144-56-45-85-262(144)203(322)142(93-106(16)17)253-193(312)140(97-159(282)283)252-200(319)163(109(20)29-3)257-195(314)143(100-264)254-201(320)164(110(21)30-4)258-197(316)145-57-46-86-263(145)204(323)146-58-47-84-261(146)154(273)99-224-169(288)122-63-72-153(272)227-122)198(317)241-129(66-75-157(278)279)181(300)231-117(51-36-40-79-209)172(291)236-125(61-70-149(214)268)178(297)238-128(65-74-156(276)277)180(299)230-118(52-37-41-80-210)173(292)237-127(64-73-155(274)275)179(298)229-116(50-35-39-78-208)171(290)235-124(60-69-148(213)267)177(296)234-123(59-68-147(212)266)170(289)226-112(23)167(286)225-113(24)168(287)243-138(95-151(216)270)192(311)249-139(96-152(217)271)191(310)233-121(55-44-83-223-207(220)221)176(295)244-133(89-102(8)9)186(305)247-135(91-104(12)13)188(307)248-136(92-105(14)15)189(308)250-141(98-160(284)285)194(313)260-166(114(25)265)202(321)259-165(205(324)325)111(22)31-5/h32-34,48-49,101-114,116-146,161-166,264-265H,27-31,35-47,50-100,208-211H2,1-26H3,(H2,212,266)(H2,213,267)(H2,214,268)(H2,215,269)(H2,216,270)(H2,217,271)(H,224,288)(H,225,286)(H,226,289)(H,227,272)(H,228,294)(H,229,298)(H,230,299)(H,231,300)(H,232,304)(H,233,310)(H,234,296)(H,235,290)(H,236,291)(H,237,292)(H,238,297)(H,239,309)(H,240,293)(H,241,317)(H,242,318)(H,243,287)(H,244,295)(H,245,301)(H,246,306)(H,247,305)(H,248,307)(H,249,311)(H,250,308)(H,251,315)(H,252,319)(H,253,312)(H,254,320)(H,255,302)(H,256,303)(H,257,314)(H,258,316)(H,259,321)(H,260,313)(H,274,275)(H,276,277)(H,278,279)(H,280,281)(H,282,283)(H,284,285)(H,324,325)(H4,218,219,222)(H4,220,221,223)/t107-,108-,109-,110-,111-,112-,113-,114+,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,161-,162-,163-,164-,165-,166-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 1.80n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro effective concentration for mouse corticotropin releasing factor 2 receptor


J Med Chem 48: 262-5 (2005)

More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 2


(Mus musculus)
BDBM50158997
PNG
(CHEMBL267635 | Sauvagine derivative)
Show InChI InChI=1S/C205H347N57O61S/c1-29-106(20)159(254-180(299)128(63-71-156(278)279)240-197(316)160(107(21)30-2)255-181(300)129(72-82-324-28)238-172(291)118(50-37-41-76-209)227-173(292)119(51-42-77-220-204(215)216)231-182(301)130(83-99(6)7)243-185(304)133(86-102(12)13)246-188(307)136(90-114-95-219-98-223-114)247-187(306)135(88-104(16)17)250-194(313)143-53-44-80-261(143)201(320)141(89-105(18)19)252-191(310)139(93-157(280)281)251-198(317)161(108(22)31-3)256-193(312)142(97-263)253-199(318)162(109(23)32-4)257-195(314)144-54-45-81-262(144)202(321)145-55-46-79-260(145)152(271)96-222-167(286)121-59-67-151(270)226-121)196(315)239-127(62-70-155(276)277)179(298)230-116(48-35-39-74-207)170(289)235-124(58-66-148(212)267)176(295)237-126(61-69-154(274)275)178(297)229-117(49-36-40-75-208)171(290)236-125(60-68-153(272)273)177(296)228-115(47-34-38-73-206)169(288)234-123(57-65-147(211)266)175(294)233-122(56-64-146(210)265)168(287)225-111(25)165(284)224-112(26)166(285)241-137(91-149(213)268)190(309)248-138(92-150(214)269)189(308)232-120(52-43-78-221-205(217)218)174(293)242-131(84-100(8)9)183(302)244-132(85-101(10)11)184(303)245-134(87-103(14)15)186(305)249-140(94-158(282)283)192(311)259-164(113(27)264)200(319)258-163(203(322)323)110(24)33-5/h95,98-113,115-145,159-164,263-264H,29-94,96-97,206-209H2,1-28H3,(H2,210,265)(H2,211,266)(H2,212,267)(H2,213,268)(H2,214,269)(H,219,223)(H,222,286)(H,224,284)(H,225,287)(H,226,270)(H,227,292)(H,228,296)(H,229,297)(H,230,298)(H,231,301)(H,232,308)(H,233,294)(H,234,288)(H,235,289)(H,236,290)(H,237,295)(H,238,291)(H,239,315)(H,240,316)(H,241,285)(H,242,293)(H,243,304)(H,244,302)(H,245,303)(H,246,307)(H,247,306)(H,248,309)(H,249,305)(H,250,313)(H,251,317)(H,252,310)(H,253,318)(H,254,299)(H,255,300)(H,256,312)(H,257,314)(H,258,319)(H,259,311)(H,272,273)(H,274,275)(H,276,277)(H,278,279)(H,280,281)(H,282,283)(H,322,323)(H4,215,216,220)(H4,217,218,221)/t106-,107-,108-,109-,110-,111-,112-,113+,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,159-,160-,161-,162-,163-,164-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 1.90n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro effective concentration for mouse corticotropin releasing factor 2 receptor


J Med Chem 48: 262-5 (2005)

More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 2


(Mus musculus)
BDBM50158982
PNG
(CHEMBL413414 | Sauvagine derivative)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H]1CCC(=O)N1)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)C(O)=O
Show InChI InChI=1S/C211H347N55O61S/c1-27-111(18)165(258-186(303)134(71-79-162(282)283)244-203(320)166(112(19)28-2)259-187(304)135(80-90-328-26)242-178(295)124(58-41-45-84-215)231-179(296)125(59-46-85-225-210(221)222)235-188(305)136(91-105(6)7)247-191(308)139(94-108(12)13)250-193(310)141(97-119-51-34-32-35-52-119)251-194(311)142(98-120-53-36-33-37-54-120)254-200(317)149-61-48-88-265(149)207(324)147(96-110(16)17)256-197(314)145(101-163(284)285)255-204(321)167(113(20)29-3)260-199(316)148(104-267)257-205(322)168(114(21)30-4)261-201(318)150-62-49-89-266(150)208(325)151-63-50-87-264(151)158(275)103-227-173(290)127-67-75-157(274)230-127)202(319)243-133(70-78-161(280)281)185(302)234-122(56-39-43-82-213)176(293)239-130(66-74-154(218)271)182(299)241-132(69-77-160(278)279)184(301)233-123(57-40-44-83-214)177(294)240-131(68-76-159(276)277)183(300)232-121(55-38-42-81-212)175(292)238-129(65-73-153(217)270)181(298)237-128(64-72-152(216)269)174(291)229-116(23)171(288)228-117(24)172(289)245-143(99-155(219)272)196(313)252-144(100-156(220)273)195(312)236-126(60-47-86-226-211(223)224)180(297)246-137(92-106(8)9)189(306)248-138(93-107(10)11)190(307)249-140(95-109(14)15)192(309)253-146(102-164(286)287)198(315)263-170(118(25)268)206(323)262-169(209(326)327)115(22)31-5/h32-37,51-54,105-118,121-151,165-170,267-268H,27-31,38-50,55-104,212-215H2,1-26H3,(H2,216,269)(H2,217,270)(H2,218,271)(H2,219,272)(H2,220,273)(H,227,290)(H,228,288)(H,229,291)(H,230,274)(H,231,296)(H,232,300)(H,233,301)(H,234,302)(H,235,305)(H,236,312)(H,237,298)(H,238,292)(H,239,293)(H,240,294)(H,241,299)(H,242,295)(H,243,319)(H,244,320)(H,245,289)(H,246,297)(H,247,308)(H,248,306)(H,249,307)(H,250,310)(H,251,311)(H,252,313)(H,253,309)(H,254,317)(H,255,321)(H,256,314)(H,257,322)(H,258,303)(H,259,304)(H,260,316)(H,261,318)(H,262,323)(H,263,315)(H,276,277)(H,278,279)(H,280,281)(H,282,283)(H,284,285)(H,286,287)(H,326,327)(H4,221,222,225)(H4,223,224,226)/t111-,112-,113-,114-,115-,116-,117-,118+,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,149-,150-,151-,165-,166-,167-,168-,169-,170-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 3n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro effective concentration for mouse corticotropin releasing factor 2 receptor


J Med Chem 48: 262-5 (2005)

More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 2


(Mus musculus)
BDBM50158985
PNG
(CHEMBL411590 | Sauvagine derivative)
Show InChI InChI=1S/C217H350N56O61S/c1-27-113(18)171(208(326)250-139(70-78-167(287)288)191(309)241-128(54-37-41-82-219)182(300)246-136(66-74-160(224)278)188(306)248-138(69-77-166(285)286)190(308)240-129(55-38-42-83-220)183(301)247-137(68-76-165(283)284)189(307)239-127(53-36-40-81-218)181(299)245-135(65-73-159(223)277)187(305)244-134(64-72-158(222)276)180(298)236-118(23)177(295)235-119(24)178(296)252-149(100-161(225)279)202(320)259-150(101-162(226)280)201(319)243-132(58-45-86-232-217(229)230)186(304)253-143(92-108(8)9)195(313)254-144(93-109(10)11)196(314)255-145(94-110(12)13)197(315)260-152(103-170(293)294)204(322)270-176(120(25)275)212(330)269-175(215(333)334)117(22)31-5)265-192(310)140(71-79-168(289)290)251-209(327)172(114(19)28-2)266-193(311)141(80-90-335-26)249-184(302)130(56-39-43-84-221)238-185(303)131(57-44-85-231-216(227)228)242-194(312)142(91-107(6)7)256-199(317)147(98-121-62-63-122-49-32-33-50-123(122)97-121)257-200(318)148(99-124-104-233-126-52-35-34-51-125(124)126)258-198(316)146(95-111(14)15)261-206(324)155-59-46-88-272(155)213(331)153(96-112(16)17)263-203(321)151(102-169(291)292)262-210(328)173(115(20)29-3)267-205(323)154(106-274)264-211(329)174(116(21)30-4)268-207(325)156-60-47-89-273(156)214(332)157-61-48-87-271(157)164(282)105-234-179(297)133-67-75-163(281)237-133/h32-35,49-52,62-63,97,104,107-120,127-157,171-176,233,274-275H,27-31,36-48,53-61,64-96,98-103,105-106,218-221H2,1-26H3,(H2,222,276)(H2,223,277)(H2,224,278)(H2,225,279)(H2,226,280)(H,234,297)(H,235,295)(H,236,298)(H,237,281)(H,238,303)(H,239,307)(H,240,308)(H,241,309)(H,242,312)(H,243,319)(H,244,305)(H,245,299)(H,246,300)(H,247,301)(H,248,306)(H,249,302)(H,250,326)(H,251,327)(H,252,296)(H,253,304)(H,254,313)(H,255,314)(H,256,317)(H,257,318)(H,258,316)(H,259,320)(H,260,315)(H,261,324)(H,262,328)(H,263,321)(H,264,329)(H,265,310)(H,266,311)(H,267,323)(H,268,325)(H,269,330)(H,270,322)(H,283,284)(H,285,286)(H,287,288)(H,289,290)(H,291,292)(H,293,294)(H,333,334)(H4,227,228,231)(H4,229,230,232)/t113-,114-,115-,116-,117-,118-,119-,120+,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,149-,150-,151-,152-,153-,154-,155-,156-,157-,171-,172-,173-,174-,175-,176-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 3.30n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro effective concentration for mouse corticotropin releasing factor 2 receptor


J Med Chem 48: 262-5 (2005)

More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 2


(Mus musculus)
BDBM50158963
PNG
(CHEMBL438220 | Sauvagine derivative)
Show InChI InChI=1S/C213H348N56O62S/c1-27-110(18)167(261-188(307)136(69-77-164(286)287)247-205(324)168(111(19)28-2)262-189(308)137(78-88-332-26)245-180(299)126(52-37-41-82-217)234-181(300)127(53-42-83-227-212(223)224)238-190(309)138(89-104(6)7)250-193(312)141(92-107(12)13)253-196(315)144(96-119-101-229-122-48-33-32-47-121(119)122)254-195(314)143(95-118-58-60-120(272)61-59-118)257-202(321)151-55-44-86-268(151)209(328)149(94-109(16)17)259-199(318)147(99-165(288)289)258-206(325)169(112(20)29-3)263-201(320)150(103-270)260-207(326)170(113(21)30-4)264-203(322)152-56-45-87-269(152)210(329)153-57-46-85-267(153)160(279)102-230-175(294)129-65-73-159(278)233-129)204(323)246-135(68-76-163(284)285)187(306)237-124(50-35-39-80-215)178(297)242-132(64-72-156(220)275)184(303)244-134(67-75-162(282)283)186(305)236-125(51-36-40-81-216)179(298)243-133(66-74-161(280)281)185(304)235-123(49-34-38-79-214)177(296)241-131(63-71-155(219)274)183(302)240-130(62-70-154(218)273)176(295)232-115(23)173(292)231-116(24)174(293)248-145(97-157(221)276)198(317)255-146(98-158(222)277)197(316)239-128(54-43-84-228-213(225)226)182(301)249-139(90-105(8)9)191(310)251-140(91-106(10)11)192(311)252-142(93-108(14)15)194(313)256-148(100-166(290)291)200(319)266-172(117(25)271)208(327)265-171(211(330)331)114(22)31-5/h32-33,47-48,58-61,101,104-117,123-153,167-172,229,270-272H,27-31,34-46,49-57,62-100,102-103,214-217H2,1-26H3,(H2,218,273)(H2,219,274)(H2,220,275)(H2,221,276)(H2,222,277)(H,230,294)(H,231,292)(H,232,295)(H,233,278)(H,234,300)(H,235,304)(H,236,305)(H,237,306)(H,238,309)(H,239,316)(H,240,302)(H,241,296)(H,242,297)(H,243,298)(H,244,303)(H,245,299)(H,246,323)(H,247,324)(H,248,293)(H,249,301)(H,250,312)(H,251,310)(H,252,311)(H,253,315)(H,254,314)(H,255,317)(H,256,313)(H,257,321)(H,258,325)(H,259,318)(H,260,326)(H,261,307)(H,262,308)(H,263,320)(H,264,322)(H,265,327)(H,266,319)(H,280,281)(H,282,283)(H,284,285)(H,286,287)(H,288,289)(H,290,291)(H,330,331)(H4,223,224,227)(H4,225,226,228)/t110-,111-,112-,113-,114-,115-,116-,117+,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,149-,150-,151-,152-,153-,167-,168-,169-,170-,171-,172-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 4n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro effective concentration for mouse corticotropin releasing factor 2 receptor


J Med Chem 48: 262-5 (2005)

More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 2


(Mus musculus)
BDBM50158952
PNG
(CHEMBL438948 | Sauvagine derivative)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H]1CCC(=O)N1)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)C(O)=O
Show InChI InChI=1S/C211H347N55O62S/c1-27-110(18)165(258-186(304)134(70-78-162(283)284)244-203(321)166(111(19)28-2)259-187(305)135(79-89-329-26)242-178(296)124(53-38-42-83-215)231-179(297)125(54-43-84-225-210(221)222)235-188(306)136(90-104(6)7)247-191(309)139(93-107(12)13)250-193(311)141(96-118-48-33-32-34-49-118)251-194(312)142(97-119-59-61-120(269)62-60-119)254-200(318)149-56-45-87-265(149)207(325)147(95-109(16)17)256-197(315)145(100-163(285)286)255-204(322)167(112(20)29-3)260-199(317)148(103-267)257-205(323)168(113(21)30-4)261-201(319)150-57-46-88-266(150)208(326)151-58-47-86-264(151)158(276)102-227-173(291)127-66-74-157(275)230-127)202(320)243-133(69-77-161(281)282)185(303)234-122(51-36-40-81-213)176(294)239-130(65-73-154(218)272)182(300)241-132(68-76-160(279)280)184(302)233-123(52-37-41-82-214)177(295)240-131(67-75-159(277)278)183(301)232-121(50-35-39-80-212)175(293)238-129(64-72-153(217)271)181(299)237-128(63-71-152(216)270)174(292)229-115(23)171(289)228-116(24)172(290)245-143(98-155(219)273)196(314)252-144(99-156(220)274)195(313)236-126(55-44-85-226-211(223)224)180(298)246-137(91-105(8)9)189(307)248-138(92-106(10)11)190(308)249-140(94-108(14)15)192(310)253-146(101-164(287)288)198(316)263-170(117(25)268)206(324)262-169(209(327)328)114(22)31-5/h32-34,48-49,59-62,104-117,121-151,165-170,267-269H,27-31,35-47,50-58,63-103,212-215H2,1-26H3,(H2,216,270)(H2,217,271)(H2,218,272)(H2,219,273)(H2,220,274)(H,227,291)(H,228,289)(H,229,292)(H,230,275)(H,231,297)(H,232,301)(H,233,302)(H,234,303)(H,235,306)(H,236,313)(H,237,299)(H,238,293)(H,239,294)(H,240,295)(H,241,300)(H,242,296)(H,243,320)(H,244,321)(H,245,290)(H,246,298)(H,247,309)(H,248,307)(H,249,308)(H,250,311)(H,251,312)(H,252,314)(H,253,310)(H,254,318)(H,255,322)(H,256,315)(H,257,323)(H,258,304)(H,259,305)(H,260,317)(H,261,319)(H,262,324)(H,263,316)(H,277,278)(H,279,280)(H,281,282)(H,283,284)(H,285,286)(H,287,288)(H,327,328)(H4,221,222,225)(H4,223,224,226)/t110-,111-,112-,113-,114-,115-,116-,117+,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,149-,150-,151-,165-,166-,167-,168-,169-,170-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 4.10n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro effective concentration for mouse corticotropin releasing factor 2 receptor


J Med Chem 48: 262-5 (2005)

More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 2


(Mus musculus)
BDBM50159002
PNG
(CHEMBL429970 | Human urocortin 2)
Show SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(O)=O
Show InChI InChI=1S/C183H323N57O52/c1-38-91(25)133(188)170(283)232-134(88(19)20)172(285)227-120(76-87(17)18)166(279)231-123(80-241)168(281)225-118(74-85(13)14)164(277)226-122(78-132(253)254)167(280)233-135(89(21)22)177(290)240-69-47-53-124(240)169(282)237-137(92(26)39-2)171(284)204-79-129(248)212-114(70-81(5)6)161(274)223-116(72-83(9)10)162(275)221-111(56-61-127(186)246)158(271)236-139(94(28)41-4)174(287)229-119(75-86(15)16)165(278)224-117(73-84(11)12)163(276)222-113(58-63-131(251)252)155(268)219-109(54-59-125(184)244)151(264)208-98(32)145(258)214-105(49-43-65-200-180(191)192)150(263)207-97(31)144(257)213-104(48-42-64-199-179(189)190)149(262)206-95(29)142(255)205-96(30)143(256)215-106(50-44-66-201-181(193)194)153(266)220-112(57-62-130(249)250)154(267)218-110(55-60-126(185)245)152(265)209-101(35)148(261)238-141(103(37)243)176(289)239-140(102(36)242)175(288)230-121(77-128(187)247)160(273)211-100(34)147(260)217-108(52-46-68-203-183(197)198)157(270)235-138(93(27)40-3)173(286)228-115(71-82(7)8)159(272)210-99(33)146(259)216-107(51-45-67-202-182(195)196)156(269)234-136(90(23)24)178(291)292/h81-124,133-141,241-243H,38-80,188H2,1-37H3,(H2,184,244)(H2,185,245)(H2,186,246)(H2,187,247)(H,204,284)(H,205,255)(H,206,262)(H,207,263)(H,208,264)(H,209,265)(H,210,272)(H,211,273)(H,212,248)(H,213,257)(H,214,258)(H,215,256)(H,216,259)(H,217,260)(H,218,267)(H,219,268)(H,220,266)(H,221,275)(H,222,276)(H,223,274)(H,224,278)(H,225,281)(H,226,277)(H,227,285)(H,228,286)(H,229,287)(H,230,288)(H,231,279)(H,232,283)(H,233,280)(H,234,269)(H,235,270)(H,236,271)(H,237,282)(H,238,261)(H,239,289)(H,249,250)(H,251,252)(H,253,254)(H,291,292)(H4,189,190,199)(H4,191,192,200)(H4,193,194,201)(H4,195,196,202)(H4,197,198,203)/t91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102+,103+,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,133-,134-,135-,136-,137-,138-,139-,140-,141-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 4.30n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro effective concentration for mouse corticotropin releasing factor 2 receptor


J Med Chem 48: 262-5 (2005)

More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 2


(Mus musculus)
BDBM50159001
PNG
(CHEMBL412026 | Sauvagine derivative)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H]1CCC(=O)N1)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)C(O)=O
Show InChI InChI=1S/C208H349N55O62S/c1-29-108(20)162(255-183(301)131(67-75-159(280)281)241-200(318)163(109(21)30-2)256-184(302)132(76-86-326-28)239-175(293)121(50-37-41-80-212)228-176(294)122(51-42-81-222-207(218)219)232-185(303)133(87-101(6)7)244-188(306)136(90-104(12)13)247-191(309)139(94-116-56-58-117(266)59-57-116)248-190(308)138(92-106(16)17)251-197(315)146-53-44-84-262(146)204(322)144(93-107(18)19)253-194(312)142(97-160(282)283)252-201(319)164(110(22)31-3)257-196(314)145(100-264)254-202(320)165(111(23)32-4)258-198(316)147-54-45-85-263(147)205(323)148-55-46-83-261(148)155(273)99-224-170(288)124-63-71-154(272)227-124)199(317)240-130(66-74-158(278)279)182(300)231-119(48-35-39-78-210)173(291)236-127(62-70-151(215)269)179(297)238-129(65-73-157(276)277)181(299)230-120(49-36-40-79-211)174(292)237-128(64-72-156(274)275)180(298)229-118(47-34-38-77-209)172(290)235-126(61-69-150(214)268)178(296)234-125(60-68-149(213)267)171(289)226-113(25)168(286)225-114(26)169(287)242-140(95-152(216)270)193(311)249-141(96-153(217)271)192(310)233-123(52-43-82-223-208(220)221)177(295)243-134(88-102(8)9)186(304)245-135(89-103(10)11)187(305)246-137(91-105(14)15)189(307)250-143(98-161(284)285)195(313)260-167(115(27)265)203(321)259-166(206(324)325)112(24)33-5/h56-59,101-115,118-148,162-167,264-266H,29-55,60-100,209-212H2,1-28H3,(H2,213,267)(H2,214,268)(H2,215,269)(H2,216,270)(H2,217,271)(H,224,288)(H,225,286)(H,226,289)(H,227,272)(H,228,294)(H,229,298)(H,230,299)(H,231,300)(H,232,303)(H,233,310)(H,234,296)(H,235,290)(H,236,291)(H,237,292)(H,238,297)(H,239,293)(H,240,317)(H,241,318)(H,242,287)(H,243,295)(H,244,306)(H,245,304)(H,246,305)(H,247,309)(H,248,308)(H,249,311)(H,250,307)(H,251,315)(H,252,319)(H,253,312)(H,254,320)(H,255,301)(H,256,302)(H,257,314)(H,258,316)(H,259,321)(H,260,313)(H,274,275)(H,276,277)(H,278,279)(H,280,281)(H,282,283)(H,284,285)(H,324,325)(H4,218,219,222)(H4,220,221,223)/t108-,109-,110-,111-,112-,113-,114-,115+,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,162-,163-,164-,165-,166-,167-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 4.30n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro effective concentration for mouse corticotropin releasing factor 2 receptor


J Med Chem 48: 262-5 (2005)

More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 2


(Mus musculus)
BDBM50159000
PNG
(CHEMBL430078 | Sauvagine derivative)
Show InChI InChI=1S/C213H348N56O61S/c1-27-111(18)167(261-188(306)136(70-78-164(285)286)247-205(323)168(112(19)28-2)262-189(307)137(79-89-331-26)245-180(298)126(57-40-44-83-217)234-181(299)127(58-45-84-227-212(223)224)238-190(308)138(90-105(6)7)250-193(311)141(93-108(12)13)253-196(314)144(97-120-102-229-122-53-36-35-52-121(120)122)254-195(313)143(96-119-50-33-32-34-51-119)257-202(320)151-60-47-87-268(151)209(327)149(95-110(16)17)259-199(317)147(100-165(287)288)258-206(324)169(113(20)29-3)263-201(319)150(104-270)260-207(325)170(114(21)30-4)264-203(321)152-61-48-88-269(152)210(328)153-62-49-86-267(153)160(278)103-230-175(293)129-66-74-159(277)233-129)204(322)246-135(69-77-163(283)284)187(305)237-124(55-38-42-81-215)178(296)242-132(65-73-156(220)274)184(302)244-134(68-76-162(281)282)186(304)236-125(56-39-43-82-216)179(297)243-133(67-75-161(279)280)185(303)235-123(54-37-41-80-214)177(295)241-131(64-72-155(219)273)183(301)240-130(63-71-154(218)272)176(294)232-116(23)173(291)231-117(24)174(292)248-145(98-157(221)275)198(316)255-146(99-158(222)276)197(315)239-128(59-46-85-228-213(225)226)182(300)249-139(91-106(8)9)191(309)251-140(92-107(10)11)192(310)252-142(94-109(14)15)194(312)256-148(101-166(289)290)200(318)266-172(118(25)271)208(326)265-171(211(329)330)115(22)31-5/h32-36,50-53,102,105-118,123-153,167-172,229,270-271H,27-31,37-49,54-101,103-104,214-217H2,1-26H3,(H2,218,272)(H2,219,273)(H2,220,274)(H2,221,275)(H2,222,276)(H,230,293)(H,231,291)(H,232,294)(H,233,277)(H,234,299)(H,235,303)(H,236,304)(H,237,305)(H,238,308)(H,239,315)(H,240,301)(H,241,295)(H,242,296)(H,243,297)(H,244,302)(H,245,298)(H,246,322)(H,247,323)(H,248,292)(H,249,300)(H,250,311)(H,251,309)(H,252,310)(H,253,314)(H,254,313)(H,255,316)(H,256,312)(H,257,320)(H,258,324)(H,259,317)(H,260,325)(H,261,306)(H,262,307)(H,263,319)(H,264,321)(H,265,326)(H,266,318)(H,279,280)(H,281,282)(H,283,284)(H,285,286)(H,287,288)(H,289,290)(H,329,330)(H4,223,224,227)(H4,225,226,228)/t111-,112-,113-,114-,115-,116-,117-,118+,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,149-,150-,151-,152-,153-,167-,168-,169-,170-,171-,172-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 4.70n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro effective concentration for mouse corticotropin releasing factor 2 receptor


J Med Chem 48: 262-5 (2005)

More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 2


(Mus musculus)
BDBM50158980
PNG
(CHEMBL410347 | Sauvagine derivative)
Show InChI InChI=1S/C210H350N56O61S/c1-29-109(20)164(258-185(303)133(67-75-161(282)283)244-202(320)165(110(21)30-2)259-186(304)134(76-86-328-28)242-177(295)123(54-39-43-80-214)231-178(296)124(55-44-81-224-209(220)221)235-187(305)135(87-102(6)7)247-190(308)138(90-105(12)13)250-193(311)141(94-117-99-226-119-50-35-34-49-118(117)119)251-192(310)140(92-107(16)17)254-199(317)148-57-46-84-265(148)206(324)146(93-108(18)19)256-196(314)144(97-162(284)285)255-203(321)166(111(22)31-3)260-198(316)147(101-267)257-204(322)167(112(23)32-4)261-200(318)149-58-47-85-266(149)207(325)150-59-48-83-264(150)157(275)100-227-172(290)126-63-71-156(274)230-126)201(319)243-132(66-74-160(280)281)184(302)234-121(52-37-41-78-212)175(293)239-129(62-70-153(217)271)181(299)241-131(65-73-159(278)279)183(301)233-122(53-38-42-79-213)176(294)240-130(64-72-158(276)277)182(300)232-120(51-36-40-77-211)174(292)238-128(61-69-152(216)270)180(298)237-127(60-68-151(215)269)173(291)229-114(25)170(288)228-115(26)171(289)245-142(95-154(218)272)195(313)252-143(96-155(219)273)194(312)236-125(56-45-82-225-210(222)223)179(297)246-136(88-103(8)9)188(306)248-137(89-104(10)11)189(307)249-139(91-106(14)15)191(309)253-145(98-163(286)287)197(315)263-169(116(27)268)205(323)262-168(208(326)327)113(24)33-5/h34-35,49-50,99,102-116,120-150,164-169,226,267-268H,29-33,36-48,51-98,100-101,211-214H2,1-28H3,(H2,215,269)(H2,216,270)(H2,217,271)(H2,218,272)(H2,219,273)(H,227,290)(H,228,288)(H,229,291)(H,230,274)(H,231,296)(H,232,300)(H,233,301)(H,234,302)(H,235,305)(H,236,312)(H,237,298)(H,238,292)(H,239,293)(H,240,294)(H,241,299)(H,242,295)(H,243,319)(H,244,320)(H,245,289)(H,246,297)(H,247,308)(H,248,306)(H,249,307)(H,250,311)(H,251,310)(H,252,313)(H,253,309)(H,254,317)(H,255,321)(H,256,314)(H,257,322)(H,258,303)(H,259,304)(H,260,316)(H,261,318)(H,262,323)(H,263,315)(H,276,277)(H,278,279)(H,280,281)(H,282,283)(H,284,285)(H,286,287)(H,326,327)(H4,220,221,224)(H4,222,223,225)/t109-,110-,111-,112-,113-,114-,115-,116+,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,149-,150-,164-,165-,166-,167-,168-,169-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 4.80n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro effective concentration for mouse corticotropin releasing factor 2 receptor


J Med Chem 48: 262-5 (2005)

More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 2


(Mus musculus)
BDBM50158971
PNG
(CHEMBL427923 | Sauvagine derivative)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H]1CCC(=O)N1)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)C(O)=O
Show InChI InChI=1S/C205H351N55O61S/c1-31-106(21)158(251-180(297)128(66-74-155(276)277)238-196(313)159(107(22)32-2)252-181(298)129(75-85-322-30)236-172(289)118(53-40-44-79-209)225-173(290)119(54-45-80-219-204(215)216)229-182(299)130(86-99(7)8)241-186(303)134(90-103(15)16)247-197(314)160(108(23)33-3)253-190(307)135(91-104(17)18)246-193(310)142-56-47-83-259(142)201(318)140(92-105(19)20)249-189(306)138(95-156(278)279)248-198(315)161(109(24)34-4)254-192(309)141(98-261)250-199(316)162(110(25)35-5)255-194(311)143-57-48-84-260(143)202(319)144-58-49-82-258(144)151(269)97-221-167(284)121-62-70-150(268)224-121)195(312)237-127(65-73-154(274)275)179(296)228-116(51-38-42-77-207)170(287)233-124(61-69-147(212)265)176(293)235-126(64-72-153(272)273)178(295)227-117(52-39-43-78-208)171(288)234-125(63-71-152(270)271)177(294)226-115(50-37-41-76-206)169(286)232-123(60-68-146(211)264)175(292)231-122(59-67-145(210)263)168(285)223-112(27)165(282)222-113(28)166(283)239-136(93-148(213)266)188(305)244-137(94-149(214)267)187(304)230-120(55-46-81-220-205(217)218)174(291)240-131(87-100(9)10)183(300)242-132(88-101(11)12)184(301)243-133(89-102(13)14)185(302)245-139(96-157(280)281)191(308)257-164(114(29)262)200(317)256-163(203(320)321)111(26)36-6/h99-144,158-164,261-262H,31-98,206-209H2,1-30H3,(H2,210,263)(H2,211,264)(H2,212,265)(H2,213,266)(H2,214,267)(H,221,284)(H,222,282)(H,223,285)(H,224,268)(H,225,290)(H,226,294)(H,227,295)(H,228,296)(H,229,299)(H,230,304)(H,231,292)(H,232,286)(H,233,287)(H,234,288)(H,235,293)(H,236,289)(H,237,312)(H,238,313)(H,239,283)(H,240,291)(H,241,303)(H,242,300)(H,243,301)(H,244,305)(H,245,302)(H,246,310)(H,247,314)(H,248,315)(H,249,306)(H,250,316)(H,251,297)(H,252,298)(H,253,307)(H,254,309)(H,255,311)(H,256,317)(H,257,308)(H,270,271)(H,272,273)(H,274,275)(H,276,277)(H,278,279)(H,280,281)(H,320,321)(H4,215,216,219)(H4,217,218,220)/t106-,107-,108-,109-,110-,111-,112-,113-,114+,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,158-,159-,160-,161-,162-,163-,164-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 5n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro effective concentration for mouse corticotropin releasing factor 2 receptor


J Med Chem 48: 262-5 (2005)

More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 2


(Mus musculus)
BDBM50158995
PNG
(CHEMBL264275 | Sauvagine derivative)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H]1CCC(=O)N1)[C@@H](C)CC)[C@@H](C)CC)C(C)C)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)C(O)=O
Show InChI InChI=1S/C207H347N55O62S/c1-29-107(20)161(254-182(300)130(67-75-157(279)280)240-199(317)162(108(21)30-2)255-183(301)131(76-86-325-28)238-174(292)120(50-37-41-80-211)227-175(293)121(51-42-81-221-206(217)218)231-184(302)132(87-100(6)7)243-188(306)136(91-104(14)15)249-197(315)160(106(18)19)253-192(310)137(93-115-56-58-116(265)59-57-115)248-195(313)144-53-44-84-261(144)203(321)142(92-105(16)17)251-191(309)140(96-158(281)282)250-200(318)163(109(22)31-3)256-194(312)143(99-263)252-201(319)164(110(23)32-4)257-196(314)145-54-45-85-262(145)204(322)146-55-46-83-260(146)153(272)98-223-169(287)123-63-71-152(271)226-123)198(316)239-129(66-74-156(277)278)181(299)230-118(48-35-39-78-209)172(290)235-126(62-70-149(214)268)178(296)237-128(65-73-155(275)276)180(298)229-119(49-36-40-79-210)173(291)236-127(64-72-154(273)274)179(297)228-117(47-34-38-77-208)171(289)234-125(61-69-148(213)267)177(295)233-124(60-68-147(212)266)170(288)225-112(25)167(285)224-113(26)168(286)241-138(94-150(215)269)190(308)246-139(95-151(216)270)189(307)232-122(52-43-82-222-207(219)220)176(294)242-133(88-101(8)9)185(303)244-134(89-102(10)11)186(304)245-135(90-103(12)13)187(305)247-141(97-159(283)284)193(311)259-166(114(27)264)202(320)258-165(205(323)324)111(24)33-5/h56-59,100-114,117-146,160-166,263-265H,29-55,60-99,208-211H2,1-28H3,(H2,212,266)(H2,213,267)(H2,214,268)(H2,215,269)(H2,216,270)(H,223,287)(H,224,285)(H,225,288)(H,226,271)(H,227,293)(H,228,297)(H,229,298)(H,230,299)(H,231,302)(H,232,307)(H,233,295)(H,234,289)(H,235,290)(H,236,291)(H,237,296)(H,238,292)(H,239,316)(H,240,317)(H,241,286)(H,242,294)(H,243,306)(H,244,303)(H,245,304)(H,246,308)(H,247,305)(H,248,313)(H,249,315)(H,250,318)(H,251,309)(H,252,319)(H,253,310)(H,254,300)(H,255,301)(H,256,312)(H,257,314)(H,258,320)(H,259,311)(H,273,274)(H,275,276)(H,277,278)(H,279,280)(H,281,282)(H,283,284)(H,323,324)(H4,217,218,221)(H4,219,220,222)/t107-,108-,109-,110-,111-,112-,113-,114+,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,160-,161-,162-,163-,164-,165-,166-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 5n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro effective concentration for mouse corticotropin releasing factor 2 receptor


J Med Chem 48: 262-5 (2005)

More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 2


(Mus musculus)
BDBM50158977
PNG
(CHEMBL438939 | Sauvagine derivative)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H]1CCC(=O)N1)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)C(O)=O
Show InChI InChI=1S/C208H349N55O62S/c1-29-108(20)162(255-183(301)131(67-75-159(280)281)241-200(318)163(109(21)30-2)256-184(302)132(76-86-326-28)239-175(293)121(50-37-41-80-212)228-176(294)122(51-42-81-222-207(218)219)232-185(303)133(87-101(6)7)244-187(305)135(89-103(10)11)246-189(307)137(91-105(14)15)248-191(309)139(94-116-56-58-117(266)59-57-116)251-197(315)146-53-44-84-262(146)204(322)144(93-107(18)19)253-194(312)142(97-160(282)283)252-201(319)164(110(22)31-3)257-196(314)145(100-264)254-202(320)165(111(23)32-4)258-198(316)147-54-45-85-263(147)205(323)148-55-46-83-261(148)155(273)99-224-170(288)124-63-71-154(272)227-124)199(317)240-130(66-74-158(278)279)182(300)231-119(48-35-39-78-210)173(291)236-127(62-70-151(215)269)179(297)238-129(65-73-157(276)277)181(299)230-120(49-36-40-79-211)174(292)237-128(64-72-156(274)275)180(298)229-118(47-34-38-77-209)172(290)235-126(61-69-150(214)268)178(296)234-125(60-68-149(213)267)171(289)226-113(25)168(286)225-114(26)169(287)242-140(95-152(216)270)193(311)249-141(96-153(217)271)192(310)233-123(52-43-82-223-208(220)221)177(295)243-134(88-102(8)9)186(304)245-136(90-104(12)13)188(306)247-138(92-106(16)17)190(308)250-143(98-161(284)285)195(313)260-167(115(27)265)203(321)259-166(206(324)325)112(24)33-5/h56-59,101-115,118-148,162-167,264-266H,29-55,60-100,209-212H2,1-28H3,(H2,213,267)(H2,214,268)(H2,215,269)(H2,216,270)(H2,217,271)(H,224,288)(H,225,286)(H,226,289)(H,227,272)(H,228,294)(H,229,298)(H,230,299)(H,231,300)(H,232,303)(H,233,310)(H,234,296)(H,235,290)(H,236,291)(H,237,292)(H,238,297)(H,239,293)(H,240,317)(H,241,318)(H,242,287)(H,243,295)(H,244,305)(H,245,304)(H,246,307)(H,247,306)(H,248,309)(H,249,311)(H,250,308)(H,251,315)(H,252,319)(H,253,312)(H,254,320)(H,255,301)(H,256,302)(H,257,314)(H,258,316)(H,259,321)(H,260,313)(H,274,275)(H,276,277)(H,278,279)(H,280,281)(H,282,283)(H,284,285)(H,324,325)(H4,218,219,222)(H4,220,221,223)/t108-,109-,110-,111-,112-,113-,114-,115+,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,162-,163-,164-,165-,166-,167-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 5.20n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro effective concentration for mouse corticotropin releasing factor 2 receptor


J Med Chem 48: 262-5 (2005)

More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 2


(Mus musculus)
BDBM50158990
PNG
(CHEMBL438601 | Sauvagine derivative)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H]1CCC(=O)N1)[C@@H](C)CC)[C@@H](C)CC)C(C)C)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)C(O)=O
Show InChI InChI=1S/C204H349N55O61S/c1-31-106(22)158(251-179(296)127(65-73-154(275)276)237-196(313)159(107(23)32-2)252-180(297)128(74-84-321-30)235-171(288)117(52-39-43-78-208)224-172(289)118(53-44-79-218-203(214)215)228-181(298)129(85-98(6)7)240-185(302)133(89-102(14)15)246-194(311)157(105(20)21)250-189(306)134(90-103(16)17)245-192(309)141-55-46-82-258(141)200(317)139(91-104(18)19)248-188(305)137(94-155(277)278)247-197(314)160(108(24)33-3)253-191(308)140(97-260)249-198(315)161(109(25)34-4)254-193(310)142-56-47-83-259(142)201(318)143-57-48-81-257(143)150(268)96-220-166(283)120-61-69-149(267)223-120)195(312)236-126(64-72-153(273)274)178(295)227-115(50-37-41-76-206)169(286)232-123(60-68-146(211)264)175(292)234-125(63-71-152(271)272)177(294)226-116(51-38-42-77-207)170(287)233-124(62-70-151(269)270)176(293)225-114(49-36-40-75-205)168(285)231-122(59-67-145(210)263)174(291)230-121(58-66-144(209)262)167(284)222-111(27)164(281)221-112(28)165(282)238-135(92-147(212)265)187(304)243-136(93-148(213)266)186(303)229-119(54-45-80-219-204(216)217)173(290)239-130(86-99(8)9)182(299)241-131(87-100(10)11)183(300)242-132(88-101(12)13)184(301)244-138(95-156(279)280)190(307)256-163(113(29)261)199(316)255-162(202(319)320)110(26)35-5/h98-143,157-163,260-261H,31-97,205-208H2,1-30H3,(H2,209,262)(H2,210,263)(H2,211,264)(H2,212,265)(H2,213,266)(H,220,283)(H,221,281)(H,222,284)(H,223,267)(H,224,289)(H,225,293)(H,226,294)(H,227,295)(H,228,298)(H,229,303)(H,230,291)(H,231,285)(H,232,286)(H,233,287)(H,234,292)(H,235,288)(H,236,312)(H,237,313)(H,238,282)(H,239,290)(H,240,302)(H,241,299)(H,242,300)(H,243,304)(H,244,301)(H,245,309)(H,246,311)(H,247,314)(H,248,305)(H,249,315)(H,250,306)(H,251,296)(H,252,297)(H,253,308)(H,254,310)(H,255,316)(H,256,307)(H,269,270)(H,271,272)(H,273,274)(H,275,276)(H,277,278)(H,279,280)(H,319,320)(H4,214,215,218)(H4,216,217,219)/t106-,107-,108-,109-,110-,111-,112-,113+,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,157-,158-,159-,160-,161-,162-,163-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 5.5n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro effective concentration for mouse corticotropin releasing factor 2 receptor


J Med Chem 48: 262-5 (2005)

More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 2


(Mus musculus)
BDBM50158953
PNG
(CHEMBL438928 | Sauvagine derivative)
Show InChI InChI=1S/C208H345N57O62S/c1-27-107(18)162(257-183(303)131(65-73-159(282)283)243-200(320)163(108(19)28-2)258-184(304)132(74-84-328-26)241-175(295)121(48-35-39-78-212)230-176(296)122(49-40-79-223-207(218)219)234-185(305)133(85-101(6)7)246-188(308)136(88-104(12)13)249-191(311)139(92-116-97-222-100-226-116)250-190(310)138(91-115-54-56-117(268)57-55-115)253-197(317)146-51-42-82-264(146)204(324)144(90-106(16)17)255-194(314)142(95-160(284)285)254-201(321)164(109(20)29-3)259-196(316)145(99-266)256-202(322)165(110(21)30-4)260-198(318)147-52-43-83-265(147)205(325)148-53-44-81-263(148)155(275)98-225-170(290)124-61-69-154(274)229-124)199(319)242-130(64-72-158(280)281)182(302)233-119(46-33-37-76-210)173(293)238-127(60-68-151(215)271)179(299)240-129(63-71-157(278)279)181(301)232-120(47-34-38-77-211)174(294)239-128(62-70-156(276)277)180(300)231-118(45-32-36-75-209)172(292)237-126(59-67-150(214)270)178(298)236-125(58-66-149(213)269)171(291)228-112(23)168(288)227-113(24)169(289)244-140(93-152(216)272)193(313)251-141(94-153(217)273)192(312)235-123(50-41-80-224-208(220)221)177(297)245-134(86-102(8)9)186(306)247-135(87-103(10)11)187(307)248-137(89-105(14)15)189(309)252-143(96-161(286)287)195(315)262-167(114(25)267)203(323)261-166(206(326)327)111(22)31-5/h54-57,97,100-114,118-148,162-167,266-268H,27-53,58-96,98-99,209-212H2,1-26H3,(H2,213,269)(H2,214,270)(H2,215,271)(H2,216,272)(H2,217,273)(H,222,226)(H,225,290)(H,227,288)(H,228,291)(H,229,274)(H,230,296)(H,231,300)(H,232,301)(H,233,302)(H,234,305)(H,235,312)(H,236,298)(H,237,292)(H,238,293)(H,239,294)(H,240,299)(H,241,295)(H,242,319)(H,243,320)(H,244,289)(H,245,297)(H,246,308)(H,247,306)(H,248,307)(H,249,311)(H,250,310)(H,251,313)(H,252,309)(H,253,317)(H,254,321)(H,255,314)(H,256,322)(H,257,303)(H,258,304)(H,259,316)(H,260,318)(H,261,323)(H,262,315)(H,276,277)(H,278,279)(H,280,281)(H,282,283)(H,284,285)(H,286,287)(H,326,327)(H4,218,219,223)(H4,220,221,224)/t107-,108-,109-,110-,111-,112-,113-,114+,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,162-,163-,164-,165-,166-,167-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 5.60n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro effective concentration for mouse corticotropin releasing factor 2 receptor


J Med Chem 48: 262-5 (2005)

More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 2


(Mus musculus)
BDBM50158979
PNG
(CHEMBL427811 | Sauvagine derivative)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1cccc2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H]1CCC(=O)N1)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)C(O)=O
Show InChI InChI=1S/C215H349N55O62S/c1-27-112(18)169(262-190(308)138(72-80-166(287)288)248-207(325)170(113(19)28-2)263-191(309)139(81-91-333-26)246-182(300)128(55-37-41-85-219)235-183(301)129(56-43-86-229-214(225)226)239-192(310)140(92-106(6)7)251-195(313)143(95-109(12)13)254-198(316)146(99-122-50-42-49-121-48-32-33-51-124(121)122)255-197(315)145(98-120-61-63-123(273)64-62-120)258-204(322)153-58-45-89-269(153)211(329)151(97-111(16)17)260-201(319)149(102-167(289)290)259-208(326)171(114(20)29-3)264-203(321)152(105-271)261-209(327)172(115(21)30-4)265-205(323)154-59-46-90-270(154)212(330)155-60-47-88-268(155)162(280)104-231-177(295)131-68-76-161(279)234-131)206(324)247-137(71-79-165(285)286)189(307)238-126(53-35-39-83-217)180(298)243-134(67-75-158(222)276)186(304)245-136(70-78-164(283)284)188(306)237-127(54-36-40-84-218)181(299)244-135(69-77-163(281)282)187(305)236-125(52-34-38-82-216)179(297)242-133(66-74-157(221)275)185(303)241-132(65-73-156(220)274)178(296)233-117(23)175(293)232-118(24)176(294)249-147(100-159(223)277)200(318)256-148(101-160(224)278)199(317)240-130(57-44-87-230-215(227)228)184(302)250-141(93-107(8)9)193(311)252-142(94-108(10)11)194(312)253-144(96-110(14)15)196(314)257-150(103-168(291)292)202(320)267-174(119(25)272)210(328)266-173(213(331)332)116(22)31-5/h32-33,42,48-51,61-64,106-119,125-155,169-174,271-273H,27-31,34-41,43-47,52-60,65-105,216-219H2,1-26H3,(H2,220,274)(H2,221,275)(H2,222,276)(H2,223,277)(H2,224,278)(H,231,295)(H,232,293)(H,233,296)(H,234,279)(H,235,301)(H,236,305)(H,237,306)(H,238,307)(H,239,310)(H,240,317)(H,241,303)(H,242,297)(H,243,298)(H,244,299)(H,245,304)(H,246,300)(H,247,324)(H,248,325)(H,249,294)(H,250,302)(H,251,313)(H,252,311)(H,253,312)(H,254,316)(H,255,315)(H,256,318)(H,257,314)(H,258,322)(H,259,326)(H,260,319)(H,261,327)(H,262,308)(H,263,309)(H,264,321)(H,265,323)(H,266,328)(H,267,320)(H,281,282)(H,283,284)(H,285,286)(H,287,288)(H,289,290)(H,291,292)(H,331,332)(H4,225,226,229)(H4,227,228,230)/t112-,113-,114-,115-,116-,117-,118-,119+,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,149-,150-,151-,152-,153-,154-,155-,169-,170-,171-,172-,173-,174-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 5.60n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro effective concentration for mouse corticotropin releasing factor 2 receptor


J Med Chem 48: 262-5 (2005)

More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 2


(Mus musculus)
BDBM50158978
PNG
(CHEMBL428824 | Sauvagine derivative)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1cccc2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H]1CCC(=O)N1)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)C(O)=O
Show InChI InChI=1S/C215H349N55O61S/c1-27-113(18)169(262-190(307)138(73-81-166(286)287)248-207(324)170(114(19)28-2)263-191(308)139(82-92-332-26)246-182(299)128(60-40-44-86-219)235-183(300)129(61-46-87-229-214(225)226)239-192(309)140(93-107(6)7)251-195(312)143(96-110(12)13)254-198(315)146(100-123-55-45-54-122-53-35-36-56-124(122)123)255-197(314)145(99-121-51-33-32-34-52-121)258-204(321)153-63-48-90-269(153)211(328)151(98-112(16)17)260-201(318)149(103-167(288)289)259-208(325)171(115(20)29-3)264-203(320)152(106-271)261-209(326)172(116(21)30-4)265-205(322)154-64-49-91-270(154)212(329)155-65-50-89-268(155)162(279)105-231-177(294)131-69-77-161(278)234-131)206(323)247-137(72-80-165(284)285)189(306)238-126(58-38-42-84-217)180(297)243-134(68-76-158(222)275)186(303)245-136(71-79-164(282)283)188(305)237-127(59-39-43-85-218)181(298)244-135(70-78-163(280)281)187(304)236-125(57-37-41-83-216)179(296)242-133(67-75-157(221)274)185(302)241-132(66-74-156(220)273)178(295)233-118(23)175(292)232-119(24)176(293)249-147(101-159(223)276)200(317)256-148(102-160(224)277)199(316)240-130(62-47-88-230-215(227)228)184(301)250-141(94-108(8)9)193(310)252-142(95-109(10)11)194(311)253-144(97-111(14)15)196(313)257-150(104-168(290)291)202(319)267-174(120(25)272)210(327)266-173(213(330)331)117(22)31-5/h32-36,45,51-56,107-120,125-155,169-174,271-272H,27-31,37-44,46-50,57-106,216-219H2,1-26H3,(H2,220,273)(H2,221,274)(H2,222,275)(H2,223,276)(H2,224,277)(H,231,294)(H,232,292)(H,233,295)(H,234,278)(H,235,300)(H,236,304)(H,237,305)(H,238,306)(H,239,309)(H,240,316)(H,241,302)(H,242,296)(H,243,297)(H,244,298)(H,245,303)(H,246,299)(H,247,323)(H,248,324)(H,249,293)(H,250,301)(H,251,312)(H,252,310)(H,253,311)(H,254,315)(H,255,314)(H,256,317)(H,257,313)(H,258,321)(H,259,325)(H,260,318)(H,261,326)(H,262,307)(H,263,308)(H,264,320)(H,265,322)(H,266,327)(H,267,319)(H,280,281)(H,282,283)(H,284,285)(H,286,287)(H,288,289)(H,290,291)(H,330,331)(H4,225,226,229)(H4,227,228,230)/t113-,114-,115-,116-,117-,118-,119-,120+,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,149-,150-,151-,152-,153-,154-,155-,169-,170-,171-,172-,173-,174-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 5.80n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro effective concentration for mouse corticotropin releasing factor 2 receptor


J Med Chem 48: 262-5 (2005)

More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 2


(Mus musculus)
BDBM50158999
PNG
(CHEMBL436914 | Sauvagine derivative)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H]1CCC(=O)N1)[C@@H](C)CC)[C@@H](C)CC)C(C)C)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)C(O)=O
Show InChI InChI=1S/C207H347N55O61S/c1-29-108(20)161(254-182(299)130(68-76-157(278)279)240-199(316)162(109(21)30-2)255-183(300)131(77-87-324-28)238-174(291)120(55-40-44-81-211)227-175(292)121(56-45-82-221-206(217)218)231-184(301)132(88-101(6)7)243-188(305)136(92-105(14)15)249-197(314)160(107(18)19)253-192(309)137(94-116-50-35-34-36-51-116)248-195(312)144-58-47-85-261(144)203(320)142(93-106(16)17)251-191(308)140(97-158(280)281)250-200(317)163(110(22)31-3)256-194(311)143(100-263)252-201(318)164(111(23)32-4)257-196(313)145-59-48-86-262(145)204(321)146-60-49-84-260(146)153(271)99-223-169(286)123-64-72-152(270)226-123)198(315)239-129(67-75-156(276)277)181(298)230-118(53-38-42-79-209)172(289)235-126(63-71-149(214)267)178(295)237-128(66-74-155(274)275)180(297)229-119(54-39-43-80-210)173(290)236-127(65-73-154(272)273)179(296)228-117(52-37-41-78-208)171(288)234-125(62-70-148(213)266)177(294)233-124(61-69-147(212)265)170(287)225-113(25)167(284)224-114(26)168(285)241-138(95-150(215)268)190(307)246-139(96-151(216)269)189(306)232-122(57-46-83-222-207(219)220)176(293)242-133(89-102(8)9)185(302)244-134(90-103(10)11)186(303)245-135(91-104(12)13)187(304)247-141(98-159(282)283)193(310)259-166(115(27)264)202(319)258-165(205(322)323)112(24)33-5/h34-36,50-51,101-115,117-146,160-166,263-264H,29-33,37-49,52-100,208-211H2,1-28H3,(H2,212,265)(H2,213,266)(H2,214,267)(H2,215,268)(H2,216,269)(H,223,286)(H,224,284)(H,225,287)(H,226,270)(H,227,292)(H,228,296)(H,229,297)(H,230,298)(H,231,301)(H,232,306)(H,233,294)(H,234,288)(H,235,289)(H,236,290)(H,237,295)(H,238,291)(H,239,315)(H,240,316)(H,241,285)(H,242,293)(H,243,305)(H,244,302)(H,245,303)(H,246,307)(H,247,304)(H,248,312)(H,249,314)(H,250,317)(H,251,308)(H,252,318)(H,253,309)(H,254,299)(H,255,300)(H,256,311)(H,257,313)(H,258,319)(H,259,310)(H,272,273)(H,274,275)(H,276,277)(H,278,279)(H,280,281)(H,282,283)(H,322,323)(H4,217,218,221)(H4,219,220,222)/t108-,109-,110-,111-,112-,113-,114-,115+,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,160-,161-,162-,163-,164-,165-,166-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 5.90n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro effective concentration for mouse corticotropin releasing factor 2 receptor


J Med Chem 48: 262-5 (2005)

More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 2


(Mus musculus)
BDBM50158956
PNG
(CHEMBL409748 | Sauvagine derivative)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H]1CCC(=O)N1)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)C(O)=O
Show InChI InChI=1S/C204H348N56O62S/c1-29-105(20)158(252-180(299)127(64-73-155(277)278)239-196(315)159(106(21)30-2)253-181(300)128(74-84-323-28)237-171(290)116(50-37-41-78-208)225-172(291)117(51-42-79-219-203(215)216)229-182(301)129(85-98(6)7)243-185(304)131(87-100(10)11)242-179(298)123(59-68-147(212)266)236-183(302)134(90-103(16)17)248-193(312)141-53-44-82-259(141)200(319)139(91-104(18)19)250-190(309)137(94-156(279)280)249-197(316)160(107(22)31-3)254-192(311)140(97-261)251-198(317)161(108(23)32-4)255-194(313)142-54-45-83-260(142)201(320)143-55-46-81-258(143)151(270)96-221-166(285)119-60-69-150(269)224-119)195(314)238-126(63-72-154(275)276)178(297)228-114(48-35-39-76-206)169(288)233-122(58-67-146(211)265)175(294)235-125(62-71-153(273)274)177(296)227-115(49-36-40-77-207)170(289)234-124(61-70-152(271)272)176(295)226-113(47-34-38-75-205)168(287)232-121(57-66-145(210)264)174(293)231-120(56-65-144(209)263)167(286)223-110(25)164(283)222-111(26)165(284)240-135(92-148(213)267)189(308)246-136(93-149(214)268)188(307)230-118(52-43-80-220-204(217)218)173(292)241-130(86-99(8)9)184(303)244-132(88-101(12)13)186(305)245-133(89-102(14)15)187(306)247-138(95-157(281)282)191(310)257-163(112(27)262)199(318)256-162(202(321)322)109(24)33-5/h98-143,158-163,261-262H,29-97,205-208H2,1-28H3,(H2,209,263)(H2,210,264)(H2,211,265)(H2,212,266)(H2,213,267)(H2,214,268)(H,221,285)(H,222,283)(H,223,286)(H,224,269)(H,225,291)(H,226,295)(H,227,296)(H,228,297)(H,229,301)(H,230,307)(H,231,293)(H,232,287)(H,233,288)(H,234,289)(H,235,294)(H,236,302)(H,237,290)(H,238,314)(H,239,315)(H,240,284)(H,241,292)(H,242,298)(H,243,304)(H,244,303)(H,245,305)(H,246,308)(H,247,306)(H,248,312)(H,249,316)(H,250,309)(H,251,317)(H,252,299)(H,253,300)(H,254,311)(H,255,313)(H,256,318)(H,257,310)(H,271,272)(H,273,274)(H,275,276)(H,277,278)(H,279,280)(H,281,282)(H,321,322)(H4,215,216,219)(H4,217,218,220)/t105-,106-,107-,108-,109-,110-,111-,112+,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,158-,159-,160-,161-,162-,163-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 6.5n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro effective concentration for mouse corticotropin releasing factor 2 receptor


J Med Chem 48: 262-5 (2005)

More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 2


(Mus musculus)
BDBM50158954
PNG
(CHEMBL442112 | Sauvagine derivative)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H]1CCC(=O)N1)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)C(O)=O
Show InChI InChI=1S/C211H347N55O63S/c1-27-109(18)165(258-186(305)134(69-77-162(284)285)244-203(322)166(110(19)28-2)259-187(306)135(78-88-330-26)242-178(297)124(48-35-39-82-215)231-179(298)125(49-40-83-225-210(221)222)235-188(307)136(89-103(6)7)247-191(310)139(92-106(12)13)250-193(312)141(95-117-54-58-119(269)59-55-117)251-194(313)142(96-118-56-60-120(270)61-57-118)254-200(319)149-51-42-86-265(149)207(326)147(94-108(16)17)256-197(316)145(99-163(286)287)255-204(323)167(111(20)29-3)260-199(318)148(102-267)257-205(324)168(112(21)30-4)261-201(320)150-52-43-87-266(150)208(327)151-53-44-85-264(151)158(277)101-227-173(292)127-65-73-157(276)230-127)202(321)243-133(68-76-161(282)283)185(304)234-122(46-33-37-80-213)176(295)239-130(64-72-154(218)273)182(301)241-132(67-75-160(280)281)184(303)233-123(47-34-38-81-214)177(296)240-131(66-74-159(278)279)183(302)232-121(45-32-36-79-212)175(294)238-129(63-71-153(217)272)181(300)237-128(62-70-152(216)271)174(293)229-114(23)171(290)228-115(24)172(291)245-143(97-155(219)274)196(315)252-144(98-156(220)275)195(314)236-126(50-41-84-226-211(223)224)180(299)246-137(90-104(8)9)189(308)248-138(91-105(10)11)190(309)249-140(93-107(14)15)192(311)253-146(100-164(288)289)198(317)263-170(116(25)268)206(325)262-169(209(328)329)113(22)31-5/h54-61,103-116,121-151,165-170,267-270H,27-53,62-102,212-215H2,1-26H3,(H2,216,271)(H2,217,272)(H2,218,273)(H2,219,274)(H2,220,275)(H,227,292)(H,228,290)(H,229,293)(H,230,276)(H,231,298)(H,232,302)(H,233,303)(H,234,304)(H,235,307)(H,236,314)(H,237,300)(H,238,294)(H,239,295)(H,240,296)(H,241,301)(H,242,297)(H,243,321)(H,244,322)(H,245,291)(H,246,299)(H,247,310)(H,248,308)(H,249,309)(H,250,312)(H,251,313)(H,252,315)(H,253,311)(H,254,319)(H,255,323)(H,256,316)(H,257,324)(H,258,305)(H,259,306)(H,260,318)(H,261,320)(H,262,325)(H,263,317)(H,278,279)(H,280,281)(H,282,283)(H,284,285)(H,286,287)(H,288,289)(H,328,329)(H4,221,222,225)(H4,223,224,226)/t109-,110-,111-,112-,113-,114-,115-,116+,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,149-,150-,151-,165-,166-,167-,168-,169-,170-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 7n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro effective concentration for mouse corticotropin releasing factor 2 receptor


J Med Chem 48: 262-5 (2005)

More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 2


(Mus musculus)
BDBM50158973
PNG
(CHEMBL438391 | Sauvagine derivative)
Show InChI InChI=1S/C212H347N57O61S/c1-27-110(18)166(261-187(306)135(68-76-163(285)286)247-204(323)167(111(19)28-2)262-188(307)136(77-87-331-26)245-179(298)125(55-37-41-81-216)234-180(299)126(56-43-82-227-211(222)223)238-189(308)137(88-104(6)7)250-192(311)140(91-107(12)13)253-194(313)142(94-119-50-42-49-118-48-32-33-51-121(118)119)254-195(314)143(95-120-100-226-103-230-120)257-201(320)150-58-45-85-268(150)208(327)148(93-109(16)17)259-198(317)146(98-164(287)288)258-205(324)168(112(20)29-3)263-200(319)149(102-270)260-206(325)169(113(21)30-4)264-202(321)151-59-46-86-269(151)209(328)152-60-47-84-267(152)159(278)101-229-174(293)128-64-72-158(277)233-128)203(322)246-134(67-75-162(283)284)186(305)237-123(53-35-39-79-214)177(296)242-131(63-71-155(219)274)183(302)244-133(66-74-161(281)282)185(304)236-124(54-36-40-80-215)178(297)243-132(65-73-160(279)280)184(303)235-122(52-34-38-78-213)176(295)241-130(62-70-154(218)273)182(301)240-129(61-69-153(217)272)175(294)232-115(23)172(291)231-116(24)173(292)248-144(96-156(220)275)197(316)255-145(97-157(221)276)196(315)239-127(57-44-83-228-212(224)225)181(300)249-138(89-105(8)9)190(309)251-139(90-106(10)11)191(310)252-141(92-108(14)15)193(312)256-147(99-165(289)290)199(318)266-171(117(25)271)207(326)265-170(210(329)330)114(22)31-5/h32-33,42,48-51,100,103-117,122-152,166-171,270-271H,27-31,34-41,43-47,52-99,101-102,213-216H2,1-26H3,(H2,217,272)(H2,218,273)(H2,219,274)(H2,220,275)(H2,221,276)(H,226,230)(H,229,293)(H,231,291)(H,232,294)(H,233,277)(H,234,299)(H,235,303)(H,236,304)(H,237,305)(H,238,308)(H,239,315)(H,240,301)(H,241,295)(H,242,296)(H,243,297)(H,244,302)(H,245,298)(H,246,322)(H,247,323)(H,248,292)(H,249,300)(H,250,311)(H,251,309)(H,252,310)(H,253,313)(H,254,314)(H,255,316)(H,256,312)(H,257,320)(H,258,324)(H,259,317)(H,260,325)(H,261,306)(H,262,307)(H,263,319)(H,264,321)(H,265,326)(H,266,318)(H,279,280)(H,281,282)(H,283,284)(H,285,286)(H,287,288)(H,289,290)(H,329,330)(H4,222,223,227)(H4,224,225,228)/t110-,111-,112-,113-,114-,115-,116-,117+,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,149-,150-,151-,152-,166-,167-,168-,169-,170-,171-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 7.20n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro effective concentration for mouse corticotropin releasing factor 2 receptor


J Med Chem 48: 262-5 (2005)

More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 2


(Mus musculus)
BDBM50158967
PNG
(CHEMBL414130 | Sauvagine derivative)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H]1CCC(=O)N1)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)C(O)=O
Show InChI InChI=1S/C205H351N55O61S/c1-31-107(22)159(252-180(297)128(65-73-156(276)277)238-197(314)160(108(23)32-2)253-181(298)129(74-84-322-30)236-172(289)118(52-39-43-78-209)225-173(290)119(53-44-79-219-204(215)216)229-182(299)130(85-99(6)7)241-184(301)132(87-101(10)11)243-186(303)134(89-103(14)15)245-188(305)136(91-105(18)19)248-194(311)143-55-46-82-259(143)201(318)141(92-106(20)21)250-191(308)139(95-157(278)279)249-198(315)161(109(24)33-3)254-193(310)142(98-261)251-199(316)162(110(25)34-4)255-195(312)144-56-47-83-260(144)202(319)145-57-48-81-258(145)152(269)97-221-167(284)121-61-69-151(268)224-121)196(313)237-127(64-72-155(274)275)179(296)228-116(50-37-41-76-207)170(287)233-124(60-68-148(212)265)176(293)235-126(63-71-154(272)273)178(295)227-117(51-38-42-77-208)171(288)234-125(62-70-153(270)271)177(294)226-115(49-36-40-75-206)169(286)232-123(59-67-147(211)264)175(292)231-122(58-66-146(210)263)168(285)223-112(27)165(282)222-113(28)166(283)239-137(93-149(213)266)190(307)246-138(94-150(214)267)189(306)230-120(54-45-80-220-205(217)218)174(291)240-131(86-100(8)9)183(300)242-133(88-102(12)13)185(302)244-135(90-104(16)17)187(304)247-140(96-158(280)281)192(309)257-164(114(29)262)200(317)256-163(203(320)321)111(26)35-5/h99-145,159-164,261-262H,31-98,206-209H2,1-30H3,(H2,210,263)(H2,211,264)(H2,212,265)(H2,213,266)(H2,214,267)(H,221,284)(H,222,282)(H,223,285)(H,224,268)(H,225,290)(H,226,294)(H,227,295)(H,228,296)(H,229,299)(H,230,306)(H,231,292)(H,232,286)(H,233,287)(H,234,288)(H,235,293)(H,236,289)(H,237,313)(H,238,314)(H,239,283)(H,240,291)(H,241,301)(H,242,300)(H,243,303)(H,244,302)(H,245,305)(H,246,307)(H,247,304)(H,248,311)(H,249,315)(H,250,308)(H,251,316)(H,252,297)(H,253,298)(H,254,310)(H,255,312)(H,256,317)(H,257,309)(H,270,271)(H,272,273)(H,274,275)(H,276,277)(H,278,279)(H,280,281)(H,320,321)(H4,215,216,219)(H4,217,218,220)/t107-,108-,109-,110-,111-,112-,113-,114+,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,159-,160-,161-,162-,163-,164-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 7.40n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro effective concentration for mouse corticotropin releasing factor 2 receptor


J Med Chem 48: 262-5 (2005)

More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 2


(Mus musculus)
BDBM50158994
PNG
(CHEMBL436912 | Sauvagine derivative)
Show InChI InChI=1S/C208H345N57O61S/c1-27-108(18)162(257-183(302)131(66-74-159(281)282)243-200(319)163(109(19)28-2)258-184(303)132(75-85-327-26)241-175(294)121(53-38-42-79-212)230-176(295)122(54-43-80-223-207(218)219)234-185(304)133(86-102(6)7)246-188(307)136(89-105(12)13)249-190(309)138(92-116-48-33-32-34-49-116)250-191(310)139(93-117-98-222-101-226-117)253-197(316)146-56-45-83-264(146)204(323)144(91-107(16)17)255-194(313)142(96-160(283)284)254-201(320)164(110(20)29-3)259-196(315)145(100-266)256-202(321)165(111(21)30-4)260-198(317)147-57-46-84-265(147)205(324)148-58-47-82-263(148)155(274)99-225-170(289)124-62-70-154(273)229-124)199(318)242-130(65-73-158(279)280)182(301)233-119(51-36-40-77-210)173(292)238-127(61-69-151(215)270)179(298)240-129(64-72-157(277)278)181(300)232-120(52-37-41-78-211)174(293)239-128(63-71-156(275)276)180(299)231-118(50-35-39-76-209)172(291)237-126(60-68-150(214)269)178(297)236-125(59-67-149(213)268)171(290)228-113(23)168(287)227-114(24)169(288)244-140(94-152(216)271)193(312)251-141(95-153(217)272)192(311)235-123(55-44-81-224-208(220)221)177(296)245-134(87-103(8)9)186(305)247-135(88-104(10)11)187(306)248-137(90-106(14)15)189(308)252-143(97-161(285)286)195(314)262-167(115(25)267)203(322)261-166(206(325)326)112(22)31-5/h32-34,48-49,98,101-115,118-148,162-167,266-267H,27-31,35-47,50-97,99-100,209-212H2,1-26H3,(H2,213,268)(H2,214,269)(H2,215,270)(H2,216,271)(H2,217,272)(H,222,226)(H,225,289)(H,227,287)(H,228,290)(H,229,273)(H,230,295)(H,231,299)(H,232,300)(H,233,301)(H,234,304)(H,235,311)(H,236,297)(H,237,291)(H,238,292)(H,239,293)(H,240,298)(H,241,294)(H,242,318)(H,243,319)(H,244,288)(H,245,296)(H,246,307)(H,247,305)(H,248,306)(H,249,309)(H,250,310)(H,251,312)(H,252,308)(H,253,316)(H,254,320)(H,255,313)(H,256,321)(H,257,302)(H,258,303)(H,259,315)(H,260,317)(H,261,322)(H,262,314)(H,275,276)(H,277,278)(H,279,280)(H,281,282)(H,283,284)(H,285,286)(H,325,326)(H4,218,219,223)(H4,220,221,224)/t108-,109-,110-,111-,112-,113-,114-,115+,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,162-,163-,164-,165-,166-,167-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 7.80n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro effective concentration for mouse corticotropin releasing factor 2 receptor


J Med Chem 48: 262-5 (2005)

More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 2


(Mus musculus)
BDBM50158992
PNG
(CHEMBL415130 | Sauvagine derivative)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H]1CCC(=O)N1)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)C(O)=O
Show InChI InChI=1S/C207H346N56O62S/c1-27-107(18)161(255-183(302)130(67-76-158(280)281)242-199(318)162(108(19)28-2)256-184(303)131(77-87-326-26)239-174(293)119(53-38-42-81-211)228-175(294)120(54-43-82-222-206(218)219)232-185(304)132(88-101(6)7)245-188(307)135(91-104(12)13)248-190(309)137(94-115-48-33-32-34-49-115)249-182(301)126(62-71-150(215)269)240-196(315)144-56-45-85-262(144)203(322)142(93-106(16)17)253-193(312)140(97-159(282)283)252-200(319)163(109(20)29-3)257-195(314)143(100-264)254-201(320)164(110(21)30-4)258-197(316)145-57-46-86-263(145)204(323)146-58-47-84-261(146)154(273)99-224-169(288)122-63-72-153(272)227-122)198(317)241-129(66-75-157(278)279)181(300)231-117(51-36-40-79-209)172(291)236-125(61-70-149(214)268)178(297)238-128(65-74-156(276)277)180(299)230-118(52-37-41-80-210)173(292)237-127(64-73-155(274)275)179(298)229-116(50-35-39-78-208)171(290)235-124(60-69-148(213)267)177(296)234-123(59-68-147(212)266)170(289)226-112(23)167(286)225-113(24)168(287)243-138(95-151(216)270)192(311)250-139(96-152(217)271)191(310)233-121(55-44-83-223-207(220)221)176(295)244-133(89-102(8)9)186(305)246-134(90-103(10)11)187(306)247-136(92-105(14)15)189(308)251-141(98-160(284)285)194(313)260-166(114(25)265)202(321)259-165(205(324)325)111(22)31-5/h32-34,48-49,101-114,116-146,161-166,264-265H,27-31,35-47,50-100,208-211H2,1-26H3,(H2,212,266)(H2,213,267)(H2,214,268)(H2,215,269)(H2,216,270)(H2,217,271)(H,224,288)(H,225,286)(H,226,289)(H,227,272)(H,228,294)(H,229,298)(H,230,299)(H,231,300)(H,232,304)(H,233,310)(H,234,296)(H,235,290)(H,236,291)(H,237,292)(H,238,297)(H,239,293)(H,240,315)(H,241,317)(H,242,318)(H,243,287)(H,244,295)(H,245,307)(H,246,305)(H,247,306)(H,248,309)(H,249,301)(H,250,311)(H,251,308)(H,252,319)(H,253,312)(H,254,320)(H,255,302)(H,256,303)(H,257,314)(H,258,316)(H,259,321)(H,260,313)(H,274,275)(H,276,277)(H,278,279)(H,280,281)(H,282,283)(H,284,285)(H,324,325)(H4,218,219,222)(H4,220,221,223)/t107-,108-,109-,110-,111-,112-,113-,114+,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,161-,162-,163-,164-,165-,166-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 8.5n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro effective concentration for mouse corticotropin releasing factor 2 receptor


J Med Chem 48: 262-5 (2005)

More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 2


(Mus musculus)
BDBM50158993
PNG
(CHEMBL437289 | Sauvagine derivative)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H]1CCC(=O)N1)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)C(O)=O
Show InChI InChI=1S/C204H348N56O62S/c1-29-104(19)157(251-180(299)127(65-74-154(277)278)239-195(314)158(105(20)30-2)253-181(300)128(75-85-323-28)236-171(290)116(51-38-42-79-208)225-172(291)117(52-43-80-219-203(215)216)229-182(301)129(86-98(7)8)242-186(305)133(90-102(15)16)247-196(315)159(106(21)31-3)252-179(298)123(60-69-146(212)266)237-192(311)140-54-45-83-259(140)200(319)138(91-103(17)18)249-189(308)136(94-155(279)280)248-197(316)160(107(22)32-4)254-191(310)139(97-261)250-198(317)161(108(23)33-5)255-193(312)141-55-46-84-260(141)201(320)142-56-47-82-258(142)150(270)96-221-166(285)119-61-70-149(269)224-119)194(313)238-126(64-73-153(275)276)178(297)228-114(49-36-40-77-206)169(288)233-122(59-68-145(211)265)175(294)235-125(63-72-152(273)274)177(296)227-115(50-37-41-78-207)170(289)234-124(62-71-151(271)272)176(295)226-113(48-35-39-76-205)168(287)232-121(58-67-144(210)264)174(293)231-120(57-66-143(209)263)167(286)223-110(25)164(283)222-111(26)165(284)240-134(92-147(213)267)188(307)245-135(93-148(214)268)187(306)230-118(53-44-81-220-204(217)218)173(292)241-130(87-99(9)10)183(302)243-131(88-100(11)12)184(303)244-132(89-101(13)14)185(304)246-137(95-156(281)282)190(309)257-163(112(27)262)199(318)256-162(202(321)322)109(24)34-6/h98-142,157-163,261-262H,29-97,205-208H2,1-28H3,(H2,209,263)(H2,210,264)(H2,211,265)(H2,212,266)(H2,213,267)(H2,214,268)(H,221,285)(H,222,283)(H,223,286)(H,224,269)(H,225,291)(H,226,295)(H,227,296)(H,228,297)(H,229,301)(H,230,306)(H,231,293)(H,232,287)(H,233,288)(H,234,289)(H,235,294)(H,236,290)(H,237,311)(H,238,313)(H,239,314)(H,240,284)(H,241,292)(H,242,305)(H,243,302)(H,244,303)(H,245,307)(H,246,304)(H,247,315)(H,248,316)(H,249,308)(H,250,317)(H,251,299)(H,252,298)(H,253,300)(H,254,310)(H,255,312)(H,256,318)(H,257,309)(H,271,272)(H,273,274)(H,275,276)(H,277,278)(H,279,280)(H,281,282)(H,321,322)(H4,215,216,219)(H4,217,218,220)/t104-,105-,106-,107-,108-,109-,110-,111-,112+,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,157-,158-,159-,160-,161-,162-,163-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 8.5n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro effective concentration for mouse corticotropin releasing factor 2 receptor


J Med Chem 48: 262-5 (2005)

More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 2


(Mus musculus)
BDBM50158972
PNG
(CHEMBL268549 | Sauvagine derivative)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H]1CCC(=O)N1)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)C(O)=O
Show InChI InChI=1S/C207H346N56O63S/c1-27-106(18)161(255-183(303)130(66-75-158(281)282)242-199(319)162(107(19)28-2)256-184(304)131(76-86-327-26)240-174(294)119(48-35-39-80-211)228-175(295)120(49-40-81-222-206(218)219)232-185(305)132(87-100(6)7)246-187(307)134(89-102(10)11)245-182(302)126(61-70-150(215)270)239-190(310)137(93-114-54-56-115(266)57-55-114)251-196(316)144-51-42-84-262(144)203(323)142(92-105(16)17)253-193(313)140(96-159(283)284)252-200(320)163(108(20)29-3)257-195(315)143(99-264)254-201(321)164(109(21)30-4)258-197(317)145-52-43-85-263(145)204(324)146-53-44-83-261(146)154(274)98-224-169(289)122-62-71-153(273)227-122)198(318)241-129(65-74-157(279)280)181(301)231-117(46-33-37-78-209)172(292)236-125(60-69-149(214)269)178(298)238-128(64-73-156(277)278)180(300)230-118(47-34-38-79-210)173(293)237-127(63-72-155(275)276)179(299)229-116(45-32-36-77-208)171(291)235-124(59-68-148(213)268)177(297)234-123(58-67-147(212)267)170(290)226-111(23)167(287)225-112(24)168(288)243-138(94-151(216)271)192(312)249-139(95-152(217)272)191(311)233-121(50-41-82-223-207(220)221)176(296)244-133(88-101(8)9)186(306)247-135(90-103(12)13)188(308)248-136(91-104(14)15)189(309)250-141(97-160(285)286)194(314)260-166(113(25)265)202(322)259-165(205(325)326)110(22)31-5/h54-57,100-113,116-146,161-166,264-266H,27-53,58-99,208-211H2,1-26H3,(H2,212,267)(H2,213,268)(H2,214,269)(H2,215,270)(H2,216,271)(H2,217,272)(H,224,289)(H,225,287)(H,226,290)(H,227,273)(H,228,295)(H,229,299)(H,230,300)(H,231,301)(H,232,305)(H,233,311)(H,234,297)(H,235,291)(H,236,292)(H,237,293)(H,238,298)(H,239,310)(H,240,294)(H,241,318)(H,242,319)(H,243,288)(H,244,296)(H,245,302)(H,246,307)(H,247,306)(H,248,308)(H,249,312)(H,250,309)(H,251,316)(H,252,320)(H,253,313)(H,254,321)(H,255,303)(H,256,304)(H,257,315)(H,258,317)(H,259,322)(H,260,314)(H,275,276)(H,277,278)(H,279,280)(H,281,282)(H,283,284)(H,285,286)(H,325,326)(H4,218,219,222)(H4,220,221,223)/t106-,107-,108-,109-,110-,111-,112-,113+,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,161-,162-,163-,164-,165-,166-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 8.60n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro effective concentration for mouse corticotropin releasing factor 2 receptor


J Med Chem 48: 262-5 (2005)

More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 2


(Mus musculus)
BDBM50158986
PNG
(CHEMBL410568 | Sauvagine derivative)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H]1CCC(=O)N1)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)C(O)=O
Show InChI InChI=1S/C206H345N55O63S/c1-28-105(18)159(252-181(300)129(66-74-156(279)280)239-197(316)160(106(19)29-2)253-182(301)130(75-85-325-27)237-173(292)119(49-36-40-79-210)226-174(293)120(50-41-80-220-205(216)217)230-183(302)131(86-99(6)7)242-187(306)135(90-103(14)15)248-200(319)164(112(25)263)257-191(310)136(92-114-55-57-115(265)58-56-114)247-194(313)143-52-43-83-260(143)202(321)141(91-104(16)17)250-190(309)139(95-157(281)282)249-198(317)161(107(20)30-3)254-193(312)142(98-262)251-199(318)162(108(21)31-4)255-195(314)144-53-44-84-261(144)203(322)145-54-45-82-259(145)152(272)97-222-168(287)122-62-70-151(271)225-122)196(315)238-128(65-73-155(277)278)180(299)229-117(47-34-38-77-208)171(290)234-125(61-69-148(213)268)177(296)236-127(64-72-154(275)276)179(298)228-118(48-35-39-78-209)172(291)235-126(63-71-153(273)274)178(297)227-116(46-33-37-76-207)170(289)233-124(60-68-147(212)267)176(295)232-123(59-67-146(211)266)169(288)224-110(23)166(285)223-111(24)167(286)240-137(93-149(214)269)189(308)245-138(94-150(215)270)188(307)231-121(51-42-81-221-206(218)219)175(294)241-132(87-100(8)9)184(303)243-133(88-101(10)11)185(304)244-134(89-102(12)13)186(305)246-140(96-158(283)284)192(311)258-165(113(26)264)201(320)256-163(204(323)324)109(22)32-5/h55-58,99-113,116-145,159-165,262-265H,28-54,59-98,207-210H2,1-27H3,(H2,211,266)(H2,212,267)(H2,213,268)(H2,214,269)(H2,215,270)(H,222,287)(H,223,285)(H,224,288)(H,225,271)(H,226,293)(H,227,297)(H,228,298)(H,229,299)(H,230,302)(H,231,307)(H,232,295)(H,233,289)(H,234,290)(H,235,291)(H,236,296)(H,237,292)(H,238,315)(H,239,316)(H,240,286)(H,241,294)(H,242,306)(H,243,303)(H,244,304)(H,245,308)(H,246,305)(H,247,313)(H,248,319)(H,249,317)(H,250,309)(H,251,318)(H,252,300)(H,253,301)(H,254,312)(H,255,314)(H,256,320)(H,257,310)(H,258,311)(H,273,274)(H,275,276)(H,277,278)(H,279,280)(H,281,282)(H,283,284)(H,323,324)(H4,216,217,220)(H4,218,219,221)/t105-,106-,107-,108-,109-,110-,111-,112+,113+,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,159-,160-,161-,162-,163-,164-,165-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 8.80n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro effective concentration for mouse corticotropin releasing factor 2 receptor


J Med Chem 48: 262-5 (2005)

More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 2


(Mus musculus)
BDBM50158974
PNG
(CHEMBL428809 | Sauvagine derivative)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H]1CCC(=O)N1)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)C(O)=O
Show InChI InChI=1S/C205H343N55O61S/c1-28-106(18)159(252-181(298)129(67-75-156(276)277)239-197(314)160(107(19)29-2)253-182(299)130(76-86-322-27)237-173(290)119(54-39-43-80-209)226-174(291)120(55-44-81-219-204(215)216)230-183(300)131(87-100(6)7)243-186(303)134(90-103(12)13)246-188(305)136(93-115-49-34-33-35-50-115)240-167(284)113(25)224-194(311)143-57-46-84-259(143)201(318)141(92-105(16)17)250-191(308)139(96-157(278)279)249-198(315)161(108(20)30-3)254-193(310)142(99-261)251-199(316)162(109(21)31-4)255-195(312)144-58-47-85-260(144)202(319)145-59-48-83-258(145)152(269)98-221-168(285)122-63-71-151(268)225-122)196(313)238-128(66-74-155(274)275)180(297)229-117(52-37-41-78-207)171(288)234-125(62-70-148(212)265)177(294)236-127(65-73-154(272)273)179(296)228-118(53-38-42-79-208)172(289)235-126(64-72-153(270)271)178(295)227-116(51-36-40-77-206)170(287)233-124(61-69-147(211)264)176(293)232-123(60-68-146(210)263)169(286)223-111(23)165(282)222-112(24)166(283)241-137(94-149(213)266)190(307)247-138(95-150(214)267)189(306)231-121(56-45-82-220-205(217)218)175(292)242-132(88-101(8)9)184(301)244-133(89-102(10)11)185(302)245-135(91-104(14)15)187(304)248-140(97-158(280)281)192(309)257-164(114(26)262)200(317)256-163(203(320)321)110(22)32-5/h33-35,49-50,100-114,116-145,159-164,261-262H,28-32,36-48,51-99,206-209H2,1-27H3,(H2,210,263)(H2,211,264)(H2,212,265)(H2,213,266)(H2,214,267)(H,221,285)(H,222,282)(H,223,286)(H,224,311)(H,225,268)(H,226,291)(H,227,295)(H,228,296)(H,229,297)(H,230,300)(H,231,306)(H,232,293)(H,233,287)(H,234,288)(H,235,289)(H,236,294)(H,237,290)(H,238,313)(H,239,314)(H,240,284)(H,241,283)(H,242,292)(H,243,303)(H,244,301)(H,245,302)(H,246,305)(H,247,307)(H,248,304)(H,249,315)(H,250,308)(H,251,316)(H,252,298)(H,253,299)(H,254,310)(H,255,312)(H,256,317)(H,257,309)(H,270,271)(H,272,273)(H,274,275)(H,276,277)(H,278,279)(H,280,281)(H,320,321)(H4,215,216,219)(H4,217,218,220)/t106-,107-,108-,109-,110-,111-,112-,113-,114+,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,159-,160-,161-,162-,163-,164-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 9.40n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro effective concentration for mouse corticotropin releasing factor 2 receptor


J Med Chem 48: 262-5 (2005)

More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 2


(Mus musculus)
BDBM50158961
PNG
(CHEMBL263862 | Sauvagine derivative)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H]1CCC(=O)N1)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)C(O)=O
Show InChI InChI=1S/C208H349N55O61S/c1-29-109(20)162(255-183(300)131(68-76-159(279)280)241-200(317)163(110(21)30-2)256-184(301)132(77-87-325-28)239-175(292)121(55-40-44-81-212)228-176(293)122(56-45-82-222-207(218)219)232-185(302)133(88-102(6)7)244-188(305)136(91-105(12)13)247-191(308)139(95-117-50-35-34-36-51-117)248-190(307)138(93-107(16)17)251-197(314)146-58-47-85-262(146)204(321)144(94-108(18)19)253-194(311)142(98-160(281)282)252-201(318)164(111(22)31-3)257-196(313)145(101-264)254-202(319)165(112(23)32-4)258-198(315)147-59-48-86-263(147)205(322)148-60-49-84-261(148)155(272)100-224-170(287)124-64-72-154(271)227-124)199(316)240-130(67-75-158(277)278)182(299)231-119(53-38-42-79-210)173(290)236-127(63-71-151(215)268)179(296)238-129(66-74-157(275)276)181(298)230-120(54-39-43-80-211)174(291)237-128(65-73-156(273)274)180(297)229-118(52-37-41-78-209)172(289)235-126(62-70-150(214)267)178(295)234-125(61-69-149(213)266)171(288)226-114(25)168(285)225-115(26)169(286)242-140(96-152(216)269)193(310)249-141(97-153(217)270)192(309)233-123(57-46-83-223-208(220)221)177(294)243-134(89-103(8)9)186(303)245-135(90-104(10)11)187(304)246-137(92-106(14)15)189(306)250-143(99-161(283)284)195(312)260-167(116(27)265)203(320)259-166(206(323)324)113(24)33-5/h34-36,50-51,102-116,118-148,162-167,264-265H,29-33,37-49,52-101,209-212H2,1-28H3,(H2,213,266)(H2,214,267)(H2,215,268)(H2,216,269)(H2,217,270)(H,224,287)(H,225,285)(H,226,288)(H,227,271)(H,228,293)(H,229,297)(H,230,298)(H,231,299)(H,232,302)(H,233,309)(H,234,295)(H,235,289)(H,236,290)(H,237,291)(H,238,296)(H,239,292)(H,240,316)(H,241,317)(H,242,286)(H,243,294)(H,244,305)(H,245,303)(H,246,304)(H,247,308)(H,248,307)(H,249,310)(H,250,306)(H,251,314)(H,252,318)(H,253,311)(H,254,319)(H,255,300)(H,256,301)(H,257,313)(H,258,315)(H,259,320)(H,260,312)(H,273,274)(H,275,276)(H,277,278)(H,279,280)(H,281,282)(H,283,284)(H,323,324)(H4,218,219,222)(H4,220,221,223)/t109-,110-,111-,112-,113-,114-,115-,116+,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,162-,163-,164-,165-,166-,167-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 10n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro effective concentration for mouse corticotropin releasing factor 2 receptor


J Med Chem 48: 262-5 (2005)

More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 2


(Mus musculus)
BDBM50158998
PNG
(CHEMBL414711 | Sauvagine derivative)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H]1CCC(=O)N1)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)C(O)=O
Show InChI InChI=1S/C204H347N55O63S/c1-29-105(20)158(251-180(299)127(64-73-155(277)278)238-196(315)159(106(21)30-2)252-181(300)128(74-84-323-28)236-171(290)116(50-37-41-78-208)224-172(291)117(51-42-79-218-203(214)215)228-182(301)129(85-98(6)7)242-185(304)131(87-100(10)11)241-179(298)125(62-71-153(273)274)235-183(302)134(90-103(16)17)247-193(312)141-53-44-82-258(141)200(319)139(91-104(18)19)249-190(309)137(94-156(279)280)248-197(316)160(107(22)31-3)253-192(311)140(97-260)250-198(317)161(108(23)32-4)254-194(313)142-54-45-83-259(142)201(320)143-55-46-81-257(143)150(268)96-220-166(285)119-59-68-149(267)223-119)195(314)237-126(63-72-154(275)276)178(297)227-114(48-35-39-76-206)169(288)232-122(58-67-146(211)264)175(294)234-124(61-70-152(271)272)177(296)226-115(49-36-40-77-207)170(289)233-123(60-69-151(269)270)176(295)225-113(47-34-38-75-205)168(287)231-121(57-66-145(210)263)174(293)230-120(56-65-144(209)262)167(286)222-110(25)164(283)221-111(26)165(284)239-135(92-147(212)265)189(308)245-136(93-148(213)266)188(307)229-118(52-43-80-219-204(216)217)173(292)240-130(86-99(8)9)184(303)243-132(88-101(12)13)186(305)244-133(89-102(14)15)187(306)246-138(95-157(281)282)191(310)256-163(112(27)261)199(318)255-162(202(321)322)109(24)33-5/h98-143,158-163,260-261H,29-97,205-208H2,1-28H3,(H2,209,262)(H2,210,263)(H2,211,264)(H2,212,265)(H2,213,266)(H,220,285)(H,221,283)(H,222,286)(H,223,267)(H,224,291)(H,225,295)(H,226,296)(H,227,297)(H,228,301)(H,229,307)(H,230,293)(H,231,287)(H,232,288)(H,233,289)(H,234,294)(H,235,302)(H,236,290)(H,237,314)(H,238,315)(H,239,284)(H,240,292)(H,241,298)(H,242,304)(H,243,303)(H,244,305)(H,245,308)(H,246,306)(H,247,312)(H,248,316)(H,249,309)(H,250,317)(H,251,299)(H,252,300)(H,253,311)(H,254,313)(H,255,318)(H,256,310)(H,269,270)(H,271,272)(H,273,274)(H,275,276)(H,277,278)(H,279,280)(H,281,282)(H,321,322)(H4,214,215,218)(H4,216,217,219)/t105-,106-,107-,108-,109-,110-,111-,112+,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,158-,159-,160-,161-,162-,163-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 11n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro effective concentration for mouse corticotropin releasing factor 2 receptor


J Med Chem 48: 262-5 (2005)

More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 2


(Mus musculus)
BDBM50158966
PNG
(CHEMBL429403 | Sauvagine derivative)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H]1CCC(=O)N1)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)C(O)=O
Show InChI InChI=1S/C207H346N56O63S/c1-27-106(18)161(255-183(303)130(66-75-158(281)282)242-199(319)162(107(19)28-2)256-184(304)131(76-86-327-26)239-174(294)119(48-35-39-80-211)228-175(295)120(49-40-81-222-206(218)219)232-185(305)132(87-100(6)7)245-188(308)135(90-103(12)13)248-190(310)137(93-114-54-56-115(266)57-55-114)249-182(302)126(61-70-150(215)270)240-196(316)144-51-42-84-262(144)203(323)142(92-105(16)17)253-193(313)140(96-159(283)284)252-200(320)163(108(20)29-3)257-195(315)143(99-264)254-201(321)164(109(21)30-4)258-197(317)145-52-43-85-263(145)204(324)146-53-44-83-261(146)154(274)98-224-169(289)122-62-71-153(273)227-122)198(318)241-129(65-74-157(279)280)181(301)231-117(46-33-37-78-209)172(292)236-125(60-69-149(214)269)178(298)238-128(64-73-156(277)278)180(300)230-118(47-34-38-79-210)173(293)237-127(63-72-155(275)276)179(299)229-116(45-32-36-77-208)171(291)235-124(59-68-148(213)268)177(297)234-123(58-67-147(212)267)170(290)226-111(23)167(287)225-112(24)168(288)243-138(94-151(216)271)192(312)250-139(95-152(217)272)191(311)233-121(50-41-82-223-207(220)221)176(296)244-133(88-101(8)9)186(306)246-134(89-102(10)11)187(307)247-136(91-104(14)15)189(309)251-141(97-160(285)286)194(314)260-166(113(25)265)202(322)259-165(205(325)326)110(22)31-5/h54-57,100-113,116-146,161-166,264-266H,27-53,58-99,208-211H2,1-26H3,(H2,212,267)(H2,213,268)(H2,214,269)(H2,215,270)(H2,216,271)(H2,217,272)(H,224,289)(H,225,287)(H,226,290)(H,227,273)(H,228,295)(H,229,299)(H,230,300)(H,231,301)(H,232,305)(H,233,311)(H,234,297)(H,235,291)(H,236,292)(H,237,293)(H,238,298)(H,239,294)(H,240,316)(H,241,318)(H,242,319)(H,243,288)(H,244,296)(H,245,308)(H,246,306)(H,247,307)(H,248,310)(H,249,302)(H,250,312)(H,251,309)(H,252,320)(H,253,313)(H,254,321)(H,255,303)(H,256,304)(H,257,315)(H,258,317)(H,259,322)(H,260,314)(H,275,276)(H,277,278)(H,279,280)(H,281,282)(H,283,284)(H,285,286)(H,325,326)(H4,218,219,222)(H4,220,221,223)/t106-,107-,108-,109-,110-,111-,112-,113+,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,161-,162-,163-,164-,165-,166-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 11n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro effective concentration for mouse corticotropin releasing factor 2 receptor


J Med Chem 48: 262-5 (2005)

More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 2


(Mus musculus)
BDBM50158975
PNG
(CHEMBL410814 | Sauvagine derivative)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1cccc2ccccc12)NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H]1CCC(=O)N1)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)C(O)=O
Show InChI InChI=1S/C209H345N55O61S/c1-28-108(18)163(256-185(302)133(69-77-160(280)281)243-201(318)164(109(19)29-2)257-186(303)134(78-88-326-27)241-177(294)123(56-38-42-82-213)230-178(295)124(57-44-83-223-208(219)220)234-187(304)135(89-102(6)7)247-190(307)138(92-105(12)13)250-192(309)140(95-118-51-43-50-117-49-33-34-52-119(117)118)244-171(288)115(25)228-198(315)147-59-46-86-263(147)205(322)145(94-107(16)17)254-195(312)143(98-161(282)283)253-202(319)165(110(20)30-3)258-197(314)146(101-265)255-203(320)166(111(21)31-4)259-199(316)148-60-47-87-264(148)206(323)149-61-48-85-262(149)156(273)100-225-172(289)126-65-73-155(272)229-126)200(317)242-132(68-76-159(278)279)184(301)233-121(54-36-40-80-211)175(292)238-129(64-72-152(216)269)181(298)240-131(67-75-158(276)277)183(300)232-122(55-37-41-81-212)176(293)239-130(66-74-157(274)275)182(299)231-120(53-35-39-79-210)174(291)237-128(63-71-151(215)268)180(297)236-127(62-70-150(214)267)173(290)227-113(23)169(286)226-114(24)170(287)245-141(96-153(217)270)194(311)251-142(97-154(218)271)193(310)235-125(58-45-84-224-209(221)222)179(296)246-136(90-103(8)9)188(305)248-137(91-104(10)11)189(306)249-139(93-106(14)15)191(308)252-144(99-162(284)285)196(313)261-168(116(26)266)204(321)260-167(207(324)325)112(22)32-5/h33-34,43,49-52,102-116,120-149,163-168,265-266H,28-32,35-42,44-48,53-101,210-213H2,1-27H3,(H2,214,267)(H2,215,268)(H2,216,269)(H2,217,270)(H2,218,271)(H,225,289)(H,226,286)(H,227,290)(H,228,315)(H,229,272)(H,230,295)(H,231,299)(H,232,300)(H,233,301)(H,234,304)(H,235,310)(H,236,297)(H,237,291)(H,238,292)(H,239,293)(H,240,298)(H,241,294)(H,242,317)(H,243,318)(H,244,288)(H,245,287)(H,246,296)(H,247,307)(H,248,305)(H,249,306)(H,250,309)(H,251,311)(H,252,308)(H,253,319)(H,254,312)(H,255,320)(H,256,302)(H,257,303)(H,258,314)(H,259,316)(H,260,321)(H,261,313)(H,274,275)(H,276,277)(H,278,279)(H,280,281)(H,282,283)(H,284,285)(H,324,325)(H4,219,220,223)(H4,221,222,224)/t108-,109-,110-,111-,112-,113-,114-,115-,116+,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,149-,163-,164-,165-,166-,167-,168-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 13n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro effective concentration for mouse corticotropin releasing factor 2 receptor


J Med Chem 48: 262-5 (2005)

More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 2


(Mus musculus)
BDBM50158958
PNG
(CHEMBL439102 | Sauvagine derivative)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H]1CCC(=O)N1)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)C(O)=O
Show InChI InChI=1S/C208H349N55O61S/c1-29-108(19)161(254-183(300)131(69-77-158(279)280)241-199(316)162(109(20)30-2)255-184(301)132(78-88-325-28)239-175(292)121(56-41-45-82-212)228-176(293)122(57-46-83-222-207(218)219)232-185(302)133(89-102(7)8)244-188(305)136(92-105(13)14)247-190(307)138(95-117-51-36-35-37-52-117)250-201(318)164(111(22)32-4)257-196(313)145-59-48-86-262(145)204(321)143(94-107(17)18)252-193(310)141(98-159(281)282)251-200(317)163(110(21)31-3)256-195(312)144(101-264)253-202(319)165(112(23)33-5)258-197(314)146-60-49-87-263(146)205(322)147-61-50-85-261(147)154(272)100-224-170(287)124-65-73-153(271)227-124)198(315)240-130(68-76-157(277)278)182(299)231-119(54-39-43-80-210)173(290)236-127(64-72-150(215)268)179(296)238-129(67-75-156(275)276)181(298)230-120(55-40-44-81-211)174(291)237-128(66-74-155(273)274)180(297)229-118(53-38-42-79-209)172(289)235-126(63-71-149(214)267)178(295)234-125(62-70-148(213)266)171(288)226-114(25)168(285)225-115(26)169(286)242-139(96-151(216)269)192(309)248-140(97-152(217)270)191(308)233-123(58-47-84-223-208(220)221)177(294)243-134(90-103(9)10)186(303)245-135(91-104(11)12)187(304)246-137(93-106(15)16)189(306)249-142(99-160(283)284)194(311)260-167(116(27)265)203(320)259-166(206(323)324)113(24)34-6/h35-37,51-52,102-116,118-147,161-167,264-265H,29-34,38-50,53-101,209-212H2,1-28H3,(H2,213,266)(H2,214,267)(H2,215,268)(H2,216,269)(H2,217,270)(H,224,287)(H,225,285)(H,226,288)(H,227,271)(H,228,293)(H,229,297)(H,230,298)(H,231,299)(H,232,302)(H,233,308)(H,234,295)(H,235,289)(H,236,290)(H,237,291)(H,238,296)(H,239,292)(H,240,315)(H,241,316)(H,242,286)(H,243,294)(H,244,305)(H,245,303)(H,246,304)(H,247,307)(H,248,309)(H,249,306)(H,250,318)(H,251,317)(H,252,310)(H,253,319)(H,254,300)(H,255,301)(H,256,312)(H,257,313)(H,258,314)(H,259,320)(H,260,311)(H,273,274)(H,275,276)(H,277,278)(H,279,280)(H,281,282)(H,283,284)(H,323,324)(H4,218,219,222)(H4,220,221,223)/t108-,109-,110-,111-,112-,113-,114-,115-,116+,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,161-,162-,163-,164-,165-,166-,167-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 13n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro effective concentration for mouse corticotropin releasing factor 2 receptor


J Med Chem 48: 262-5 (2005)

More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 2


(Homo sapiens (Human))
BDBM50087704
PNG
(CHEMBL265635 | r/h-CRF(SEEPPISLDLTFHLLREVLEMARAEQL...)
Show InChI InChI=1S/C208H344N60O63S2/c1-30-106(20)161(165(215)291)263-202(328)163(108(22)32-3)264-184(310)129(58-67-157(285)286)243-182(308)131(70-78-333-29)246-187(313)134(80-99(6)7)250-176(302)118(45-36-37-71-209)237-174(300)120(47-39-73-225-207(218)219)239-194(320)143(89-152(214)276)256-197(323)145(94-270)260-193(319)141(87-115-91-222-96-227-115)248-169(295)112(26)230-172(298)122(51-60-149(211)273)240-177(303)123(52-61-150(212)274)234-168(294)111(25)232-185(311)133(79-98(4)5)249-181(307)124(53-62-151(213)275)241-178(304)125(54-63-153(277)278)235-167(293)110(24)229-171(297)119(46-38-72-224-206(216)217)233-166(292)109(23)231-173(299)130(69-77-332-28)245-179(305)127(56-65-155(281)282)244-188(314)138(84-103(14)15)258-200(326)160(105(18)19)262-183(309)128(57-66-156(283)284)242-175(301)121(48-40-74-226-208(220)221)238-186(312)135(81-100(8)9)251-189(315)136(82-101(10)11)252-192(318)142(88-116-92-223-97-228-116)255-191(317)140(86-114-43-34-33-35-44-114)259-203(329)164(113(27)272)266-196(322)139(85-104(16)17)253-195(321)144(90-159(289)290)257-190(316)137(83-102(12)13)254-198(324)146(95-271)261-201(327)162(107(21)31-2)265-199(325)147-49-41-75-267(147)205(331)148-50-42-76-268(148)204(330)132(59-68-158(287)288)247-180(306)126(55-64-154(279)280)236-170(296)117(210)93-269/h33-35,43-44,91-92,96-113,117-148,160-164,269-272H,30-32,36-42,45-90,93-95,209-210H2,1-29H3,(H2,211,273)(H2,212,274)(H2,213,275)(H2,214,276)(H2,215,291)(H,222,227)(H,223,228)(H,229,297)(H,230,298)(H,231,299)(H,232,311)(H,233,292)(H,234,294)(H,235,293)(H,236,296)(H,237,300)(H,238,312)(H,239,320)(H,240,303)(H,241,304)(H,242,301)(H,243,308)(H,244,314)(H,245,305)(H,246,313)(H,247,306)(H,248,295)(H,249,307)(H,250,302)(H,251,315)(H,252,318)(H,253,321)(H,254,324)(H,255,317)(H,256,323)(H,257,316)(H,258,326)(H,259,329)(H,260,319)(H,261,327)(H,262,309)(H,263,328)(H,264,310)(H,265,325)(H,266,322)(H,277,278)(H,279,280)(H,281,282)(H,283,284)(H,285,286)(H,287,288)(H,289,290)(H4,216,217,224)(H4,218,219,225)(H4,220,221,226)/t106-,107-,108-,109+,110+,111-,112-,113?,117-,118-,119-,120-,121-,122+,123-,124-,125-,126-,127-,128-,129-,130-,131-,132+,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148+,160-,161-,162-,163-,164-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/an/an/a 13.2n/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
Activity of peptidic agonists on h-CRF2-alpha receptor using agonist-stimulated adenylate cyclase assay


J Med Chem 43: 1641-60 (2000)

More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 2


(Mus musculus)
BDBM50158968
PNG
(CHEMBL427611 | Sauvagine derivative)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1cccc2ccccc12)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H]1CCC(=O)N1)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)C(O)=O
Show InChI InChI=1S/C211H348N56O62S/c1-27-109(18)165(259-187(306)134(69-78-162(284)285)246-203(322)166(110(19)28-2)260-188(307)135(79-89-330-26)243-178(297)123(55-37-41-83-215)232-179(298)124(56-43-84-226-210(222)223)236-189(308)136(90-103(6)7)249-192(311)139(93-106(12)13)252-194(313)141(96-118-50-42-49-117-48-32-33-51-119(117)118)253-186(305)130(64-73-154(219)273)244-200(319)148-58-45-87-266(148)207(326)146(95-108(16)17)257-197(316)144(99-163(286)287)256-204(323)167(111(20)29-3)261-199(318)147(102-268)258-205(324)168(112(21)30-4)262-201(320)149-59-46-88-267(149)208(327)150-60-47-86-265(150)158(277)101-228-173(292)126-65-74-157(276)231-126)202(321)245-133(68-77-161(282)283)185(304)235-121(53-35-39-81-213)176(295)240-129(63-72-153(218)272)182(301)242-132(67-76-160(280)281)184(303)234-122(54-36-40-82-214)177(296)241-131(66-75-159(278)279)183(302)233-120(52-34-38-80-212)175(294)239-128(62-71-152(217)271)181(300)238-127(61-70-151(216)270)174(293)230-114(23)171(290)229-115(24)172(291)247-142(97-155(220)274)196(315)254-143(98-156(221)275)195(314)237-125(57-44-85-227-211(224)225)180(299)248-137(91-104(8)9)190(309)250-138(92-105(10)11)191(310)251-140(94-107(14)15)193(312)255-145(100-164(288)289)198(317)264-170(116(25)269)206(325)263-169(209(328)329)113(22)31-5/h32-33,42,48-51,103-116,120-150,165-170,268-269H,27-31,34-41,43-47,52-102,212-215H2,1-26H3,(H2,216,270)(H2,217,271)(H2,218,272)(H2,219,273)(H2,220,274)(H2,221,275)(H,228,292)(H,229,290)(H,230,293)(H,231,276)(H,232,298)(H,233,302)(H,234,303)(H,235,304)(H,236,308)(H,237,314)(H,238,300)(H,239,294)(H,240,295)(H,241,296)(H,242,301)(H,243,297)(H,244,319)(H,245,321)(H,246,322)(H,247,291)(H,248,299)(H,249,311)(H,250,309)(H,251,310)(H,252,313)(H,253,305)(H,254,315)(H,255,312)(H,256,323)(H,257,316)(H,258,324)(H,259,306)(H,260,307)(H,261,318)(H,262,320)(H,263,325)(H,264,317)(H,278,279)(H,280,281)(H,282,283)(H,284,285)(H,286,287)(H,288,289)(H,328,329)(H4,222,223,226)(H4,224,225,227)/t109-,110-,111-,112-,113-,114-,115-,116+,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,149-,150-,165-,166-,167-,168-,169-,170-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 14n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro effective concentration for mouse corticotropin releasing factor 2 receptor


J Med Chem 48: 262-5 (2005)

More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 2


(Mus musculus)
BDBM50158955
PNG
(CHEMBL414568 | Sauvagine derivative)
Show InChI InChI=1S/C208H346N56O62S/c1-28-106(18)161(255-183(302)131(66-74-158(281)282)242-199(318)162(107(19)29-2)256-184(303)132(75-85-327-27)240-175(294)121(53-38-42-79-212)229-176(295)122(54-43-80-222-207(218)219)233-185(304)133(86-100(6)7)245-188(307)136(89-103(12)13)248-190(309)138(92-115-97-224-117-49-34-33-48-116(115)117)251-202(321)166(113(25)266)261-197(316)145-56-45-83-263(145)204(323)143(91-105(16)17)253-193(312)141(95-159(283)284)252-200(319)163(108(20)30-3)257-195(314)144(99-265)254-201(320)164(109(21)31-4)258-196(315)146-57-46-84-264(146)205(324)147-58-47-82-262(147)154(274)98-225-170(289)124-62-70-153(273)228-124)198(317)241-130(65-73-157(279)280)182(301)232-119(51-36-40-77-210)173(292)237-127(61-69-150(215)270)179(298)239-129(64-72-156(277)278)181(300)231-120(52-37-41-78-211)174(293)238-128(63-71-155(275)276)180(299)230-118(50-35-39-76-209)172(291)236-126(60-68-149(214)269)178(297)235-125(59-67-148(213)268)171(290)227-111(23)168(287)226-112(24)169(288)243-139(93-151(216)271)192(311)249-140(94-152(217)272)191(310)234-123(55-44-81-223-208(220)221)177(296)244-134(87-101(8)9)186(305)246-135(88-102(10)11)187(306)247-137(90-104(14)15)189(308)250-142(96-160(285)286)194(313)260-167(114(26)267)203(322)259-165(206(325)326)110(22)32-5/h33-34,48-49,97,100-114,118-147,161-167,224,265-267H,28-32,35-47,50-96,98-99,209-212H2,1-27H3,(H2,213,268)(H2,214,269)(H2,215,270)(H2,216,271)(H2,217,272)(H,225,289)(H,226,287)(H,227,290)(H,228,273)(H,229,295)(H,230,299)(H,231,300)(H,232,301)(H,233,304)(H,234,310)(H,235,297)(H,236,291)(H,237,292)(H,238,293)(H,239,298)(H,240,294)(H,241,317)(H,242,318)(H,243,288)(H,244,296)(H,245,307)(H,246,305)(H,247,306)(H,248,309)(H,249,311)(H,250,308)(H,251,321)(H,252,319)(H,253,312)(H,254,320)(H,255,302)(H,256,303)(H,257,314)(H,258,315)(H,259,322)(H,260,313)(H,261,316)(H,275,276)(H,277,278)(H,279,280)(H,281,282)(H,283,284)(H,285,286)(H,325,326)(H4,218,219,222)(H4,220,221,223)/t106-,107-,108-,109-,110-,111-,112-,113+,114+,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,161-,162-,163-,164-,165-,166-,167-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 15n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro effective concentration for mouse corticotropin releasing factor 2 receptor


J Med Chem 48: 262-5 (2005)

More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 2


(Mus musculus)
BDBM50158970
PNG
(CHEMBL441564 | Sauvagine derivative)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H]1CCC(=O)N1)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)C(O)=O
Show InChI InChI=1S/C205H351N55O61S/c1-31-105(20)157(250-180(297)128(67-75-154(276)277)238-195(312)158(106(21)32-2)251-181(298)129(76-86-322-30)236-172(289)118(54-41-45-80-209)225-173(290)119(55-46-81-219-204(215)216)229-182(299)130(87-99(8)9)241-186(303)134(91-103(16)17)246-197(314)161(109(24)35-5)255-199(316)162(110(25)36-6)254-192(309)141-57-48-84-259(141)201(318)139(92-104(18)19)248-189(306)137(95-155(278)279)247-196(313)159(107(22)33-3)252-191(308)140(98-261)249-198(315)160(108(23)34-4)253-193(310)142-58-49-85-260(142)202(319)143-59-50-83-258(143)150(269)97-221-167(284)121-63-71-149(268)224-121)194(311)237-127(66-74-153(274)275)179(296)228-116(52-39-43-78-207)170(287)233-124(62-70-146(212)265)176(293)235-126(65-73-152(272)273)178(295)227-117(53-40-44-79-208)171(288)234-125(64-72-151(270)271)177(294)226-115(51-38-42-77-206)169(286)232-123(61-69-145(211)264)175(292)231-122(60-68-144(210)263)168(285)223-112(27)165(282)222-113(28)166(283)239-135(93-147(213)266)188(305)244-136(94-148(214)267)187(304)230-120(56-47-82-220-205(217)218)174(291)240-131(88-100(10)11)183(300)242-132(89-101(12)13)184(301)243-133(90-102(14)15)185(302)245-138(96-156(280)281)190(307)257-164(114(29)262)200(317)256-163(203(320)321)111(26)37-7/h99-143,157-164,261-262H,31-98,206-209H2,1-30H3,(H2,210,263)(H2,211,264)(H2,212,265)(H2,213,266)(H2,214,267)(H,221,284)(H,222,282)(H,223,285)(H,224,268)(H,225,290)(H,226,294)(H,227,295)(H,228,296)(H,229,299)(H,230,304)(H,231,292)(H,232,286)(H,233,287)(H,234,288)(H,235,293)(H,236,289)(H,237,311)(H,238,312)(H,239,283)(H,240,291)(H,241,303)(H,242,300)(H,243,301)(H,244,305)(H,245,302)(H,246,314)(H,247,313)(H,248,306)(H,249,315)(H,250,297)(H,251,298)(H,252,308)(H,253,310)(H,254,309)(H,255,316)(H,256,317)(H,257,307)(H,270,271)(H,272,273)(H,274,275)(H,276,277)(H,278,279)(H,280,281)(H,320,321)(H4,215,216,219)(H4,217,218,220)/t105-,106-,107-,108-,109-,110-,111-,112-,113-,114+,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,157-,158-,159-,160-,161-,162-,163-,164-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 15n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro effective concentration for mouse corticotropin releasing factor 2 receptor


J Med Chem 48: 262-5 (2005)

More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 2


(Mus musculus)
BDBM50158969
PNG
(CHEMBL428975 | Sauvagine derivative)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H]1CCC(=O)N1)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)C(O)=O
Show InChI InChI=1S/C205H351N55O61S/c1-31-106(21)158(251-180(297)128(66-74-155(276)277)238-196(313)159(107(22)32-2)252-181(298)129(75-85-322-30)236-172(289)118(53-40-44-79-209)225-173(290)119(54-45-80-219-204(215)216)229-182(299)130(86-99(7)8)241-184(301)133(89-102(13)14)244-187(304)135(91-104(17)18)247-198(315)161(109(24)34-4)254-193(310)142-56-47-83-259(142)201(318)140(92-105(19)20)249-190(307)138(95-156(278)279)248-197(314)160(108(23)33-3)253-192(309)141(98-261)250-199(316)162(110(25)35-5)255-194(311)143-57-48-84-260(143)202(319)144-58-49-82-258(144)151(269)97-221-167(284)121-62-70-150(268)224-121)195(312)237-127(65-73-154(274)275)179(296)228-116(51-38-42-77-207)170(287)233-124(61-69-147(212)265)176(293)235-126(64-72-153(272)273)178(295)227-117(52-39-43-78-208)171(288)234-125(63-71-152(270)271)177(294)226-115(50-37-41-76-206)169(286)232-123(60-68-146(211)264)175(292)231-122(59-67-145(210)263)168(285)223-112(27)165(282)222-113(28)166(283)239-136(93-148(213)266)189(306)245-137(94-149(214)267)188(305)230-120(55-46-81-220-205(217)218)174(291)240-131(87-100(9)10)183(300)242-132(88-101(11)12)185(302)243-134(90-103(15)16)186(303)246-139(96-157(280)281)191(308)257-164(114(29)262)200(317)256-163(203(320)321)111(26)36-6/h99-144,158-164,261-262H,31-98,206-209H2,1-30H3,(H2,210,263)(H2,211,264)(H2,212,265)(H2,213,266)(H2,214,267)(H,221,284)(H,222,282)(H,223,285)(H,224,268)(H,225,290)(H,226,294)(H,227,295)(H,228,296)(H,229,299)(H,230,305)(H,231,292)(H,232,286)(H,233,287)(H,234,288)(H,235,293)(H,236,289)(H,237,312)(H,238,313)(H,239,283)(H,240,291)(H,241,301)(H,242,300)(H,243,302)(H,244,304)(H,245,306)(H,246,303)(H,247,315)(H,248,314)(H,249,307)(H,250,316)(H,251,297)(H,252,298)(H,253,309)(H,254,310)(H,255,311)(H,256,317)(H,257,308)(H,270,271)(H,272,273)(H,274,275)(H,276,277)(H,278,279)(H,280,281)(H,320,321)(H4,215,216,219)(H4,217,218,220)/t106-,107-,108-,109-,110-,111-,112-,113-,114+,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,158-,159-,160-,161-,162-,163-,164-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 16n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro effective concentration for mouse corticotropin releasing factor 2 receptor


J Med Chem 48: 262-5 (2005)

More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 2


(Mus musculus)
BDBM50158991
PNG
(CHEMBL438210 | Sauvagine derivative)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1cccc2ccccc12)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H]1CCC(=O)N1)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)C(O)=O
Show InChI InChI=1S/C212H351N55O61S/c1-29-110(19)165(258-187(304)135(71-79-162(283)284)245-203(320)166(111(20)30-2)259-188(305)136(80-90-329-28)243-179(296)125(58-40-44-84-216)232-180(297)126(59-46-85-226-211(222)223)236-189(306)137(91-104(7)8)248-192(309)140(94-107(13)14)251-194(311)142(97-120-53-45-52-119-51-35-36-54-121(119)120)254-205(322)168(113(22)32-4)261-200(317)149-61-48-88-266(149)208(325)147(96-109(17)18)256-197(314)145(100-163(285)286)255-204(321)167(112(21)31-3)260-199(316)148(103-268)257-206(323)169(114(23)33-5)262-201(318)150-62-49-89-267(150)209(326)151-63-50-87-265(151)158(276)102-228-174(291)128-67-75-157(275)231-128)202(319)244-134(70-78-161(281)282)186(303)235-123(56-38-42-82-214)177(294)240-131(66-74-154(219)272)183(300)242-133(69-77-160(279)280)185(302)234-124(57-39-43-83-215)178(295)241-132(68-76-159(277)278)184(301)233-122(55-37-41-81-213)176(293)239-130(65-73-153(218)271)182(299)238-129(64-72-152(217)270)175(292)230-116(25)172(289)229-117(26)173(290)246-143(98-155(220)273)196(313)252-144(99-156(221)274)195(312)237-127(60-47-86-227-212(224)225)181(298)247-138(92-105(9)10)190(307)249-139(93-106(11)12)191(308)250-141(95-108(15)16)193(310)253-146(101-164(287)288)198(315)264-171(118(27)269)207(324)263-170(210(327)328)115(24)34-6/h35-36,45,51-54,104-118,122-151,165-171,268-269H,29-34,37-44,46-50,55-103,213-216H2,1-28H3,(H2,217,270)(H2,218,271)(H2,219,272)(H2,220,273)(H2,221,274)(H,228,291)(H,229,289)(H,230,292)(H,231,275)(H,232,297)(H,233,301)(H,234,302)(H,235,303)(H,236,306)(H,237,312)(H,238,299)(H,239,293)(H,240,294)(H,241,295)(H,242,300)(H,243,296)(H,244,319)(H,245,320)(H,246,290)(H,247,298)(H,248,309)(H,249,307)(H,250,308)(H,251,311)(H,252,313)(H,253,310)(H,254,322)(H,255,321)(H,256,314)(H,257,323)(H,258,304)(H,259,305)(H,260,316)(H,261,317)(H,262,318)(H,263,324)(H,264,315)(H,277,278)(H,279,280)(H,281,282)(H,283,284)(H,285,286)(H,287,288)(H,327,328)(H4,222,223,226)(H4,224,225,227)/t110-,111-,112-,113-,114-,115-,116-,117-,118+,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,149-,150-,151-,165-,166-,167-,168-,169-,170-,171-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 16n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro effective concentration for mouse corticotropin releasing factor 2 receptor


J Med Chem 48: 262-5 (2005)

More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 2


(Mus musculus)
BDBM50158976
PNG
(CHEMBL429243 | Sauvagine derivative)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H]1CCC(=O)N1)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)C(O)=O
Show InChI InChI=1S/C206H345N55O63S/c1-28-105(18)159(252-181(300)129(66-74-156(279)280)239-197(316)160(106(19)29-2)253-182(301)130(75-85-325-27)237-173(292)119(49-36-40-79-210)226-174(293)120(50-41-80-220-205(216)217)230-183(302)131(86-99(6)7)242-186(305)134(89-102(12)13)245-188(307)136(92-114-55-57-115(265)58-56-114)248-200(319)164(112(25)263)258-195(314)143-52-43-83-260(143)202(321)141(91-104(16)17)250-191(310)139(95-157(281)282)249-198(317)161(107(20)30-3)254-193(312)142(98-262)251-199(318)162(108(21)31-4)255-194(313)144-53-44-84-261(144)203(322)145-54-45-82-259(145)152(272)97-222-168(287)122-62-70-151(271)225-122)196(315)238-128(65-73-155(277)278)180(299)229-117(47-34-38-77-208)171(290)234-125(61-69-148(213)268)177(296)236-127(64-72-154(275)276)179(298)228-118(48-35-39-78-209)172(291)235-126(63-71-153(273)274)178(297)227-116(46-33-37-76-207)170(289)233-124(60-68-147(212)267)176(295)232-123(59-67-146(211)266)169(288)224-110(23)166(285)223-111(24)167(286)240-137(93-149(214)269)190(309)246-138(94-150(215)270)189(308)231-121(51-42-81-221-206(218)219)175(294)241-132(87-100(8)9)184(303)243-133(88-101(10)11)185(304)244-135(90-103(14)15)187(306)247-140(96-158(283)284)192(311)257-165(113(26)264)201(320)256-163(204(323)324)109(22)32-5/h55-58,99-113,116-145,159-165,262-265H,28-54,59-98,207-210H2,1-27H3,(H2,211,266)(H2,212,267)(H2,213,268)(H2,214,269)(H2,215,270)(H,222,287)(H,223,285)(H,224,288)(H,225,271)(H,226,293)(H,227,297)(H,228,298)(H,229,299)(H,230,302)(H,231,308)(H,232,295)(H,233,289)(H,234,290)(H,235,291)(H,236,296)(H,237,292)(H,238,315)(H,239,316)(H,240,286)(H,241,294)(H,242,305)(H,243,303)(H,244,304)(H,245,307)(H,246,309)(H,247,306)(H,248,319)(H,249,317)(H,250,310)(H,251,318)(H,252,300)(H,253,301)(H,254,312)(H,255,313)(H,256,320)(H,257,311)(H,258,314)(H,273,274)(H,275,276)(H,277,278)(H,279,280)(H,281,282)(H,283,284)(H,323,324)(H4,216,217,220)(H4,218,219,221)/t105-,106-,107-,108-,109-,110-,111-,112+,113+,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,159-,160-,161-,162-,163-,164-,165-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 18n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro effective concentration for mouse corticotropin releasing factor 2 receptor


J Med Chem 48: 262-5 (2005)

More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 2


(Mus musculus)
BDBM50158987
PNG
(CHEMBL439887 | Sauvagine derivative)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H]1CCC(=O)N1)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)C(O)=O
Show InChI InChI=1S/C203H347N55O62S/c1-30-103(19)155(248-178(296)126(65-73-152(275)276)236-193(311)156(104(20)31-2)249-179(297)127(74-84-321-29)234-170(288)116(52-39-43-78-207)223-171(289)117(53-44-79-217-202(213)214)227-180(298)128(85-97(7)8)239-184(302)132(89-101(15)16)244-195(313)159(107(23)34-5)252-197(315)162(112(28)261)255-191(309)139-55-46-82-257(139)199(317)137(90-102(17)18)246-187(305)135(93-153(277)278)245-194(312)157(105(21)32-3)250-189(307)138(96-259)247-196(314)158(106(22)33-4)251-190(308)140-56-47-83-258(140)200(318)141-57-48-81-256(141)148(268)95-219-165(283)119-61-69-147(267)222-119)192(310)235-125(64-72-151(273)274)177(295)226-114(50-37-41-76-205)168(286)231-122(60-68-144(210)264)174(292)233-124(63-71-150(271)272)176(294)225-115(51-38-42-77-206)169(287)232-123(62-70-149(269)270)175(293)224-113(49-36-40-75-204)167(285)230-121(59-67-143(209)263)173(291)229-120(58-66-142(208)262)166(284)221-109(25)163(281)220-110(26)164(282)237-133(91-145(211)265)186(304)242-134(92-146(212)266)185(303)228-118(54-45-80-218-203(215)216)172(290)238-129(86-98(9)10)181(299)240-130(87-99(11)12)182(300)241-131(88-100(13)14)183(301)243-136(94-154(279)280)188(306)254-161(111(27)260)198(316)253-160(201(319)320)108(24)35-6/h97-141,155-162,259-261H,30-96,204-207H2,1-29H3,(H2,208,262)(H2,209,263)(H2,210,264)(H2,211,265)(H2,212,266)(H,219,283)(H,220,281)(H,221,284)(H,222,267)(H,223,289)(H,224,293)(H,225,294)(H,226,295)(H,227,298)(H,228,303)(H,229,291)(H,230,285)(H,231,286)(H,232,287)(H,233,292)(H,234,288)(H,235,310)(H,236,311)(H,237,282)(H,238,290)(H,239,302)(H,240,299)(H,241,300)(H,242,304)(H,243,301)(H,244,313)(H,245,312)(H,246,305)(H,247,314)(H,248,296)(H,249,297)(H,250,307)(H,251,308)(H,252,315)(H,253,316)(H,254,306)(H,255,309)(H,269,270)(H,271,272)(H,273,274)(H,275,276)(H,277,278)(H,279,280)(H,319,320)(H4,213,214,217)(H4,215,216,218)/t103-,104-,105-,106-,107-,108-,109-,110-,111+,112+,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,155-,156-,157-,158-,159-,160-,161-,162-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 19n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro effective concentration for mouse corticotropin releasing factor 2 receptor


J Med Chem 48: 262-5 (2005)

More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 2


(Mus musculus)
BDBM50159004
PNG
(CHEMBL441929 | Sauvagine derivative)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H]1CCC(=O)N1)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)C(O)=O
Show InChI InChI=1S/C206H345N55O62S/c1-28-106(18)159(252-181(299)129(67-75-156(278)279)239-197(315)160(107(19)29-2)253-182(300)130(76-86-324-27)237-173(291)119(54-39-43-80-210)226-174(292)120(55-44-81-220-205(216)217)230-183(301)131(87-100(6)7)242-186(304)134(90-103(12)13)245-188(306)136(93-115-49-34-33-35-50-115)248-200(318)164(113(25)263)258-195(313)143-57-46-84-260(143)202(320)141(92-105(16)17)250-191(309)139(96-157(280)281)249-198(316)161(108(20)30-3)254-193(311)142(99-262)251-199(317)162(109(21)31-4)255-194(312)144-58-47-85-261(144)203(321)145-59-48-83-259(145)152(271)98-222-168(286)122-63-71-151(270)225-122)196(314)238-128(66-74-155(276)277)180(298)229-117(52-37-41-78-208)171(289)234-125(62-70-148(213)267)177(295)236-127(65-73-154(274)275)179(297)228-118(53-38-42-79-209)172(290)235-126(64-72-153(272)273)178(296)227-116(51-36-40-77-207)170(288)233-124(61-69-147(212)266)176(294)232-123(60-68-146(211)265)169(287)224-111(23)166(284)223-112(24)167(285)240-137(94-149(214)268)190(308)246-138(95-150(215)269)189(307)231-121(56-45-82-221-206(218)219)175(293)241-132(88-101(8)9)184(302)243-133(89-102(10)11)185(303)244-135(91-104(14)15)187(305)247-140(97-158(282)283)192(310)257-165(114(26)264)201(319)256-163(204(322)323)110(22)32-5/h33-35,49-50,100-114,116-145,159-165,262-264H,28-32,36-48,51-99,207-210H2,1-27H3,(H2,211,265)(H2,212,266)(H2,213,267)(H2,214,268)(H2,215,269)(H,222,286)(H,223,284)(H,224,287)(H,225,270)(H,226,292)(H,227,296)(H,228,297)(H,229,298)(H,230,301)(H,231,307)(H,232,294)(H,233,288)(H,234,289)(H,235,290)(H,236,295)(H,237,291)(H,238,314)(H,239,315)(H,240,285)(H,241,293)(H,242,304)(H,243,302)(H,244,303)(H,245,306)(H,246,308)(H,247,305)(H,248,318)(H,249,316)(H,250,309)(H,251,317)(H,252,299)(H,253,300)(H,254,311)(H,255,312)(H,256,319)(H,257,310)(H,258,313)(H,272,273)(H,274,275)(H,276,277)(H,278,279)(H,280,281)(H,282,283)(H,322,323)(H4,216,217,220)(H4,218,219,221)/t106-,107-,108-,109-,110-,111-,112-,113+,114+,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,159-,160-,161-,162-,163-,164-,165-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 19n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro effective concentration for mouse corticotropin releasing factor 2 receptor


J Med Chem 48: 262-5 (2005)

More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 2


(Mus musculus)
BDBM50158959
PNG
(CHEMBL429719 | Sauvagine derivative)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H]1CCC(=O)N1)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)C(O)=O
Show InChI InChI=1S/C205H343N55O62S/c1-28-105(18)159(252-181(299)129(66-74-156(277)278)239-197(315)160(106(19)29-2)253-182(300)130(75-85-323-27)237-173(291)119(49-36-40-79-209)226-174(292)120(50-41-80-219-204(215)216)230-183(301)131(86-99(6)7)243-186(304)134(89-102(12)13)246-188(306)136(92-114-55-57-115(263)58-56-114)240-167(285)112(25)224-194(312)143-52-43-83-259(143)201(319)141(91-104(16)17)250-191(309)139(95-157(279)280)249-198(316)161(107(20)30-3)254-193(311)142(98-261)251-199(317)162(108(21)31-4)255-195(313)144-53-44-84-260(144)202(320)145-54-45-82-258(145)152(270)97-221-168(286)122-62-70-151(269)225-122)196(314)238-128(65-73-155(275)276)180(298)229-117(47-34-38-77-207)171(289)234-125(61-69-148(212)266)177(295)236-127(64-72-154(273)274)179(297)228-118(48-35-39-78-208)172(290)235-126(63-71-153(271)272)178(296)227-116(46-33-37-76-206)170(288)233-124(60-68-147(211)265)176(294)232-123(59-67-146(210)264)169(287)223-110(23)165(283)222-111(24)166(284)241-137(93-149(213)267)190(308)247-138(94-150(214)268)189(307)231-121(51-42-81-220-205(217)218)175(293)242-132(87-100(8)9)184(302)244-133(88-101(10)11)185(303)245-135(90-103(14)15)187(305)248-140(96-158(281)282)192(310)257-164(113(26)262)200(318)256-163(203(321)322)109(22)32-5/h55-58,99-113,116-145,159-164,261-263H,28-54,59-98,206-209H2,1-27H3,(H2,210,264)(H2,211,265)(H2,212,266)(H2,213,267)(H2,214,268)(H,221,286)(H,222,283)(H,223,287)(H,224,312)(H,225,269)(H,226,292)(H,227,296)(H,228,297)(H,229,298)(H,230,301)(H,231,307)(H,232,294)(H,233,288)(H,234,289)(H,235,290)(H,236,295)(H,237,291)(H,238,314)(H,239,315)(H,240,285)(H,241,284)(H,242,293)(H,243,304)(H,244,302)(H,245,303)(H,246,306)(H,247,308)(H,248,305)(H,249,316)(H,250,309)(H,251,317)(H,252,299)(H,253,300)(H,254,311)(H,255,313)(H,256,318)(H,257,310)(H,271,272)(H,273,274)(H,275,276)(H,277,278)(H,279,280)(H,281,282)(H,321,322)(H4,215,216,219)(H4,217,218,220)/t105-,106-,107-,108-,109-,110-,111-,112-,113+,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,159-,160-,161-,162-,163-,164-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 20n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro effective concentration for mouse corticotropin releasing factor 2 receptor


J Med Chem 48: 262-5 (2005)

More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 2


(Mus musculus)
BDBM50159003
PNG
(CHEMBL409626 | Sauvagine derivative)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H]1CCC(=O)N1)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)C(O)=O
Show InChI InChI=1S/C203H347N55O62S/c1-30-104(20)156(249-178(296)126(64-72-153(275)276)236-194(312)157(105(21)31-2)250-179(297)127(73-83-321-29)234-170(288)116(51-38-42-77-207)223-171(289)117(52-43-78-217-202(213)214)227-180(298)128(84-97(6)7)239-182(300)131(87-100(12)13)242-185(303)133(89-102(16)17)245-197(315)161(111(27)260)255-192(310)140-54-45-81-257(140)199(317)138(90-103(18)19)247-188(306)136(93-154(277)278)246-195(313)158(106(22)32-3)251-190(308)139(96-259)248-196(314)159(107(23)33-4)252-191(309)141-55-46-82-258(141)200(318)142-56-47-80-256(142)149(268)95-219-165(283)119-60-68-148(267)222-119)193(311)235-125(63-71-152(273)274)177(295)226-114(49-36-40-75-205)168(286)231-122(59-67-145(210)264)174(292)233-124(62-70-151(271)272)176(294)225-115(50-37-41-76-206)169(287)232-123(61-69-150(269)270)175(293)224-113(48-35-39-74-204)167(285)230-121(58-66-144(209)263)173(291)229-120(57-65-143(208)262)166(284)221-109(25)163(281)220-110(26)164(282)237-134(91-146(211)265)187(305)243-135(92-147(212)266)186(304)228-118(53-44-79-218-203(215)216)172(290)238-129(85-98(8)9)181(299)240-130(86-99(10)11)183(301)241-132(88-101(14)15)184(302)244-137(94-155(279)280)189(307)254-162(112(28)261)198(316)253-160(201(319)320)108(24)34-5/h97-142,156-162,259-261H,30-96,204-207H2,1-29H3,(H2,208,262)(H2,209,263)(H2,210,264)(H2,211,265)(H2,212,266)(H,219,283)(H,220,281)(H,221,284)(H,222,267)(H,223,289)(H,224,293)(H,225,294)(H,226,295)(H,227,298)(H,228,304)(H,229,291)(H,230,285)(H,231,286)(H,232,287)(H,233,292)(H,234,288)(H,235,311)(H,236,312)(H,237,282)(H,238,290)(H,239,300)(H,240,299)(H,241,301)(H,242,303)(H,243,305)(H,244,302)(H,245,315)(H,246,313)(H,247,306)(H,248,314)(H,249,296)(H,250,297)(H,251,308)(H,252,309)(H,253,316)(H,254,307)(H,255,310)(H,269,270)(H,271,272)(H,273,274)(H,275,276)(H,277,278)(H,279,280)(H,319,320)(H4,213,214,217)(H4,215,216,218)/t104-,105-,106-,107-,108-,109-,110-,111+,112+,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,156-,157-,158-,159-,160-,161-,162-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 21n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro effective concentration for mouse corticotropin releasing factor 2 receptor


J Med Chem 48: 262-5 (2005)

More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 2


(Mus musculus)
BDBM50158984
PNG
(CHEMBL427792 | Sauvagine derivative)
Show InChI InChI=1S/C204H344N58O62S/c1-27-104(18)158(254-180(301)127(62-71-155(279)280)241-196(317)159(105(19)28-2)255-181(302)128(72-82-325-26)239-171(292)116(48-35-39-76-208)227-172(293)117(49-40-77-220-203(215)216)231-182(303)129(83-98(6)7)245-184(305)131(85-100(10)11)244-179(300)123(57-66-147(212)268)238-187(308)134(89-112-94-219-97-223-112)250-193(314)141-51-42-80-261(141)200(321)139(88-103(16)17)252-190(311)137(92-156(281)282)251-197(318)160(106(20)29-3)256-192(313)140(96-263)253-198(319)161(107(21)30-4)257-194(315)142-52-43-81-262(142)201(322)143-53-44-79-260(143)151(272)95-222-166(287)119-58-67-150(271)226-119)195(316)240-126(61-70-154(277)278)178(299)230-114(46-33-37-74-206)169(290)235-122(56-65-146(211)267)175(296)237-125(60-69-153(275)276)177(298)229-115(47-34-38-75-207)170(291)236-124(59-68-152(273)274)176(297)228-113(45-32-36-73-205)168(289)234-121(55-64-145(210)266)174(295)233-120(54-63-144(209)265)167(288)225-109(23)164(285)224-110(24)165(286)242-135(90-148(213)269)189(310)248-136(91-149(214)270)188(309)232-118(50-41-78-221-204(217)218)173(294)243-130(84-99(8)9)183(304)246-132(86-101(12)13)185(306)247-133(87-102(14)15)186(307)249-138(93-157(283)284)191(312)259-163(111(25)264)199(320)258-162(202(323)324)108(22)31-5/h94,97-111,113-143,158-163,263-264H,27-93,95-96,205-208H2,1-26H3,(H2,209,265)(H2,210,266)(H2,211,267)(H2,212,268)(H2,213,269)(H2,214,270)(H,219,223)(H,222,287)(H,224,285)(H,225,288)(H,226,271)(H,227,293)(H,228,297)(H,229,298)(H,230,299)(H,231,303)(H,232,309)(H,233,295)(H,234,289)(H,235,290)(H,236,291)(H,237,296)(H,238,308)(H,239,292)(H,240,316)(H,241,317)(H,242,286)(H,243,294)(H,244,300)(H,245,305)(H,246,304)(H,247,306)(H,248,310)(H,249,307)(H,250,314)(H,251,318)(H,252,311)(H,253,319)(H,254,301)(H,255,302)(H,256,313)(H,257,315)(H,258,320)(H,259,312)(H,273,274)(H,275,276)(H,277,278)(H,279,280)(H,281,282)(H,283,284)(H,323,324)(H4,215,216,220)(H4,217,218,221)/t104-,105-,106-,107-,108-,109-,110-,111+,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,158-,159-,160-,161-,162-,163-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 21n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro effective concentration for mouse corticotropin releasing factor 2 receptor


J Med Chem 48: 262-5 (2005)

More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 2


(Mus musculus)
BDBM50158957
PNG
(CHEMBL411961 | Sauvagine derivative)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H]1CCC(=O)N1)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)C(O)=O
Show InChI InChI=1S/C208H349N55O62S/c1-29-107(19)161(254-183(301)131(68-76-158(280)281)241-199(317)162(108(20)30-2)255-184(302)132(77-87-326-28)239-175(293)121(51-38-42-81-212)228-176(294)122(52-43-82-222-207(218)219)232-185(303)133(88-101(7)8)244-188(306)136(91-104(13)14)247-190(308)138(94-116-57-59-117(266)60-58-116)250-201(319)164(110(22)32-4)257-196(314)145-54-45-85-262(145)204(322)143(93-106(17)18)252-193(311)141(97-159(282)283)251-200(318)163(109(21)31-3)256-195(313)144(100-264)253-202(320)165(111(23)33-5)258-197(315)146-55-46-86-263(146)205(323)147-56-47-84-261(147)154(273)99-224-170(288)124-64-72-153(272)227-124)198(316)240-130(67-75-157(278)279)182(300)231-119(49-36-40-79-210)173(291)236-127(63-71-150(215)269)179(297)238-129(66-74-156(276)277)181(299)230-120(50-37-41-80-211)174(292)237-128(65-73-155(274)275)180(298)229-118(48-35-39-78-209)172(290)235-126(62-70-149(214)268)178(296)234-125(61-69-148(213)267)171(289)226-113(25)168(286)225-114(26)169(287)242-139(95-151(216)270)192(310)248-140(96-152(217)271)191(309)233-123(53-44-83-223-208(220)221)177(295)243-134(89-102(9)10)186(304)245-135(90-103(11)12)187(305)246-137(92-105(15)16)189(307)249-142(98-160(284)285)194(312)260-167(115(27)265)203(321)259-166(206(324)325)112(24)34-6/h57-60,101-115,118-147,161-167,264-266H,29-56,61-100,209-212H2,1-28H3,(H2,213,267)(H2,214,268)(H2,215,269)(H2,216,270)(H2,217,271)(H,224,288)(H,225,286)(H,226,289)(H,227,272)(H,228,294)(H,229,298)(H,230,299)(H,231,300)(H,232,303)(H,233,309)(H,234,296)(H,235,290)(H,236,291)(H,237,292)(H,238,297)(H,239,293)(H,240,316)(H,241,317)(H,242,287)(H,243,295)(H,244,306)(H,245,304)(H,246,305)(H,247,308)(H,248,310)(H,249,307)(H,250,319)(H,251,318)(H,252,311)(H,253,320)(H,254,301)(H,255,302)(H,256,313)(H,257,314)(H,258,315)(H,259,321)(H,260,312)(H,274,275)(H,276,277)(H,278,279)(H,280,281)(H,282,283)(H,284,285)(H,324,325)(H4,218,219,222)(H4,220,221,223)/t107-,108-,109-,110-,111-,112-,113-,114-,115+,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,161-,162-,163-,164-,165-,166-,167-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 22n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro effective concentration for mouse corticotropin releasing factor 2 receptor


J Med Chem 48: 262-5 (2005)

More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 2


(Mus musculus)
BDBM50158988
PNG
(CHEMBL412296 | Sauvagine derivative)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H]1CCC(=O)N1)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)C(O)=O
Show InChI InChI=1S/C201H343N55O61S/c1-29-104(20)156(248-178(295)125(63-71-153(273)274)236-193(310)157(105(21)30-2)249-179(296)126(72-82-318-28)234-170(287)115(50-37-41-76-205)223-171(288)116(51-42-77-215-200(211)212)227-181(298)129(85-99(10)11)239-180(297)128(84-98(8)9)222-148(265)94-217-165(282)127(83-97(6)7)244-190(307)139-53-44-80-255(139)197(314)137(89-103(18)19)246-187(304)135(92-154(275)276)245-194(311)158(106(22)31-3)250-189(306)138(96-257)247-195(312)159(107(23)32-4)251-191(308)140-54-45-81-256(140)198(315)141-55-46-79-254(141)149(266)95-218-164(281)118-59-67-147(264)221-118)192(309)235-124(62-70-152(271)272)177(294)226-113(48-35-39-74-203)168(285)231-121(58-66-144(208)261)174(291)233-123(61-69-151(269)270)176(293)225-114(49-36-40-75-204)169(286)232-122(60-68-150(267)268)175(292)224-112(47-34-38-73-202)167(284)230-120(57-65-143(207)260)173(290)229-119(56-64-142(206)259)166(283)220-109(25)162(279)219-110(26)163(280)237-133(90-145(209)262)186(303)242-134(91-146(210)263)185(302)228-117(52-43-78-216-201(213)214)172(289)238-130(86-100(12)13)182(299)240-131(87-101(14)15)183(300)241-132(88-102(16)17)184(301)243-136(93-155(277)278)188(305)253-161(111(27)258)196(313)252-160(199(316)317)108(24)33-5/h97-141,156-161,257-258H,29-96,202-205H2,1-28H3,(H2,206,259)(H2,207,260)(H2,208,261)(H2,209,262)(H2,210,263)(H,217,282)(H,218,281)(H,219,279)(H,220,283)(H,221,264)(H,222,265)(H,223,288)(H,224,292)(H,225,293)(H,226,294)(H,227,298)(H,228,302)(H,229,290)(H,230,284)(H,231,285)(H,232,286)(H,233,291)(H,234,287)(H,235,309)(H,236,310)(H,237,280)(H,238,289)(H,239,297)(H,240,299)(H,241,300)(H,242,303)(H,243,301)(H,244,307)(H,245,311)(H,246,304)(H,247,312)(H,248,295)(H,249,296)(H,250,306)(H,251,308)(H,252,313)(H,253,305)(H,267,268)(H,269,270)(H,271,272)(H,273,274)(H,275,276)(H,277,278)(H,316,317)(H4,211,212,215)(H4,213,214,216)/t104-,105-,106-,107-,108-,109-,110-,111+,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,156-,157-,158-,159-,160-,161-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 22n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro effective concentration for mouse corticotropin releasing factor 2 receptor


J Med Chem 48: 262-5 (2005)

More data for this
Ligand-Target Pair
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