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Compile Data Set for Download or QSAR

Found 5 hits of ec50 data for polymerid = 50002849,9680   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
alpha-1 Nicotinic AChR


(Homo sapiens (Human))
BDBM50049756
PNG
(3-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-pyridine |...)
Show SMILES CN1CCC[C@H]1COc1cccnc1
Show InChI InChI=1S/C11H16N2O/c1-13-7-3-4-10(13)9-14-11-5-2-6-12-8-11/h2,5-6,8,10H,3-4,7,9H2,1H3/t10-/m0/s1
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n/an/an/an/a 3.40E+4n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested for functional activity against alpha1 neuronal nicotinic acetylcholine receptor(nAChR) expressed in TE671 cells using isotopic rubidium efflu...


Citation and Details
More data for this
Ligand-Target Pair
alpha-1 Nicotinic AChR


(Homo sapiens (Human))
BDBM50290628
PNG
(2-((S)-1-Methyl-pyrrolidin-2-yl)-furo[3,2-b]pyridi...)
Show SMILES CN1CCC[C@H]1c1cc2ncccc2o1
Show InChI InChI=1S/C12H14N2O/c1-14-7-3-4-10(14)12-8-9-11(15-12)5-2-6-13-9/h2,5-6,8,10H,3-4,7H2,1H3/t10-/m0/s1
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n/an/an/an/a>1.00E+5n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested for functional activity against alpha1 neuronal nicotinic acetylcholine receptor(nAChR) expressed in TE671 cells using isotopic rubidium efflu...


Citation and Details
More data for this
Ligand-Target Pair
alpha-1 Nicotinic AChR


(Homo sapiens (Human))
BDBM82070
PNG
(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Show SMILES CN1CCC[C@H]1c1cccnc1
Show InChI InChI=1S/C10H14N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2,4,6,8,10H,3,5,7H2,1H3/t10-/m0/s1
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KEGG
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PDB
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Article
n/an/an/an/a 1.80E+5n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested for functional activity against alpha1 neuronal nicotinic acetylcholine receptor(nAChR) expressed in TE671 cells using isotopic rubidium efflu...


Citation and Details
More data for this
Ligand-Target Pair
alpha-1 Nicotinic AChR


(Homo sapiens (Human))
BDBM50035398
PNG
((S)-1-Methyl-2-(3-methyl-isoxazol-5-yl)-pyrrolidin...)
Show SMILES CN1CCC[C@H]1c1cc(C)no1
Show InChI InChI=1S/C9H14N2O/c1-7-6-9(12-10-7)8-4-3-5-11(8)2/h6,8H,3-5H2,1-2H3/t8-/m0/s1
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Article
n/an/an/an/a 4.11E+5n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested for functional activity against alpha1 neuronal nicotinic acetylcholine receptor(nAChR) expressed in TE671 cells using isotopic rubidium efflu...


Citation and Details
More data for this
Ligand-Target Pair
alpha-1 Nicotinic AChR


(Homo sapiens (Human))
BDBM50290629
PNG
((S)-2-Pyrrolidin-2-yl-furo[3,2-b]pyridine | CHEMBL...)
Show SMILES C1CN[C@@H](C1)c1cc2ncccc2o1
Show InChI InChI=1S/C11H12N2O/c1-3-8(12-5-1)11-7-9-10(14-11)4-2-6-13-9/h2,4,6-8,12H,1,3,5H2/t8-/m0/s1
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Article
n/an/an/an/a>1.00E+6n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested for functional activity against neuronal nicotinic acetylcholine receptor(nAChR) expressed in K177 cells using isotopic rubidium efflux assay.


Citation and Details
More data for this
Ligand-Target Pair