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Compile Data Set for Download or QSAR

Found 4 hits of ec50 data for polymerid = 50004217,6277   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
20S proteasome chymotrypsin-like


(Homo sapiens (Human))
BDBM50444464
PNG
(CHEMBL192046)
Show SMILES C[C@@]12OC(=O)[C@@]1(NC(=O)[C@@H]2CCCl)[C@@H](O)C1CCCCC1
Show InChI InChI=1S/C15H22ClNO4/c1-14-10(7-8-16)12(19)17-15(14,13(20)21-14)11(18)9-5-3-2-4-6-9/h9-11,18H,2-8H2,1H3,(H,17,19)/t10-,11-,14-,15-/m0/s1
PDB
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PC cid
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Article
PubMed
n/an/an/an/a 10n/an/an/an/a



The Pennsylvania State University

Curated by ChEMBL


Assay Description
Inhibition of chymotrypsin like activity of 20S proteasome in HEK293 cells after 24 hrs by microscopic analysis


Citation and Details
More data for this
Ligand-Target Pair
20S proteasome chymotrypsin-like


(Homo sapiens (Human))
BDBM50444463
PNG
(CHEMBL3092608)
Show SMILES C[C@@]12OC(=O)[C@@]1(NC(=O)[C@@H]2CCCCl)[C@@H](O)C1CCCCC1
Show InChI InChI=1S/C16H24ClNO4/c1-15-11(8-5-9-17)13(20)18-16(15,14(21)22-15)12(19)10-6-3-2-4-7-10/h10-12,19H,2-9H2,1H3,(H,18,20)/t11-,12-,15-,16-/m0/s1
PDB
MMDB

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KEGG

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CHEMBL
PC cid
PC sid
UniChem

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Article
PubMed
n/an/an/an/a 90n/an/an/an/a



The Pennsylvania State University

Curated by ChEMBL


Assay Description
Inhibition of chymotrypsin like activity of 20S proteasome in HEK293 cells after 24 hrs by microscopic analysis


Citation and Details
More data for this
Ligand-Target Pair
20S proteasome chymotrypsin-like


(Homo sapiens (Human))
BDBM50444461
PNG
(CHEMBL3092610)
Show SMILES C[C@@]12OC(=O)[C@@]1(NC(=O)[C@@H]2CCCl)[C@@H](O)Cc1ccccc1
Show InChI InChI=1S/C16H18ClNO4/c1-15-11(7-8-17)13(20)18-16(15,14(21)22-15)12(19)9-10-5-3-2-4-6-10/h2-6,11-12,19H,7-9H2,1H3,(H,18,20)/t11-,12-,15-,16-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

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DrugBank
antibodypedia
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CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/an/an/a 332n/an/an/an/a



The Pennsylvania State University

Curated by ChEMBL


Assay Description
Inhibition of chymotrypsin like activity of 20S proteasome in HEK293 cells after 24 hrs by microscopic analysis


Citation and Details
More data for this
Ligand-Target Pair
20S proteasome chymotrypsin-like


(Homo sapiens (Human))
BDBM50444462
PNG
(CHEMBL3092609)
Show SMILES C[C@@]12OC(=O)[C@@]1(NC(=O)[C@@H]2CCCl)[C@@H](O)C1CC1
Show InChI InChI=1S/C12H16ClNO4/c1-11-7(4-5-13)9(16)14-12(11,10(17)18-11)8(15)6-2-3-6/h6-8,15H,2-5H2,1H3,(H,14,16)/t7-,8-,11-,12-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 360n/an/an/an/a



The Pennsylvania State University

Curated by ChEMBL


Assay Description
Inhibition of chymotrypsin like activity of 20S proteasome in HEK293 cells after 24 hrs by microscopic analysis


Citation and Details
More data for this
Ligand-Target Pair