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Compile Data Set for Download or QSAR

Found 4 hits of ec50 data for polymerid = 50006043   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Axin-2


(Homo sapiens)
BDBM50318567
PNG
(2-(4-(Trifluoromethyl)phenyl)-7,8-dihydro-5H-thiop...)
Show SMILES FC(F)(F)c1ccc(cc1)-c1nc2CCSCc2c(=O)[nH]1
Show InChI InChI=1S/C14H11F3N2OS/c15-14(16,17)9-3-1-8(2-4-9)12-18-11-5-6-21-7-10(11)13(20)19-12/h1-4H,5-7H2,(H,18,19,20)
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n/an/an/an/a 371n/an/an/an/a



Novartis Institutes for Biomedical Research

Curated by ChEMBL


Assay Description
Stabilization of Axin2 in human SW480 cells after 24 hrs by sandwich ELISA


J Med Chem 55: 1127-36 (2012)

More data for this
Ligand-Target Pair
Axin-2


(Homo sapiens)
BDBM50380595
PNG
(CHEMBL1867804)
Show SMILES COc1ccc(cc1)-n1c(C)nnc1SCc1nc(no1)-c1ccc(OC)c(OC)c1
Show InChI InChI=1S/C21H21N5O4S/c1-13-23-24-21(26(13)15-6-8-16(27-2)9-7-15)31-12-19-22-20(25-30-19)14-5-10-17(28-3)18(11-14)29-4/h5-11H,12H2,1-4H3
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n/an/an/an/a 375n/an/an/an/a



Novartis Institutes for Biomedical Research

Curated by ChEMBL


Assay Description
Stabilization of Axin2 in human SW480 cells after 24 hrs by sandwich ELISA


J Med Chem 55: 1127-36 (2012)

More data for this
Ligand-Target Pair
Axin-2


(Homo sapiens)
BDBM50380592
PNG
(CHEMBL1552719)
Show SMILES COc1ccc(cc1)-n1c(SCc2nc(no2)-c2ccc(C)cc2)nnc1-c1ccncc1
Show InChI InChI=1S/C24H20N6O2S/c1-16-3-5-17(6-4-16)22-26-21(32-29-22)15-33-24-28-27-23(18-11-13-25-14-12-18)30(24)19-7-9-20(31-2)10-8-19/h3-14H,15H2,1-2H3
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PubMed
n/an/an/an/a 566n/an/an/an/a



Novartis Institutes for Biomedical Research

Curated by ChEMBL


Assay Description
Stabilization of Axin2 in human SW480 cells after 24 hrs by sandwich ELISA


J Med Chem 55: 1127-36 (2012)

More data for this
Ligand-Target Pair
Axin-2


(Homo sapiens)
BDBM50380590
PNG
(CHEMBL1898239)
Show SMILES COc1ccc(cc1)-c1noc(CSc2nnc(C)n2-c2ccc(OC)cc2)n1
Show InChI InChI=1S/C20H19N5O3S/c1-13-22-23-20(25(13)15-6-10-17(27-3)11-7-15)29-12-18-21-19(24-28-18)14-4-8-16(26-2)9-5-14/h4-11H,12H2,1-3H3
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PC cid
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UniChem

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Article
PubMed
n/an/an/an/a 709n/an/an/an/a



Novartis Institutes for Biomedical Research

Curated by ChEMBL


Assay Description
Stabilization of Axin2 in human SW480 cells after 24 hrs by sandwich ELISA


J Med Chem 55: 1127-36 (2012)

More data for this
Ligand-Target Pair