Compile Data Set for Download or QSAR
maximum 50k data
Found 71 of ec50 data for polymerid = 7256
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50096735(CHEMBL2372983 | Compound T140)
Affinity DataEC50:  0.180nMAssay Description:Effective concentration of the compound for antagonistic activity by inhibition of T-tropic strain of HIV-1 through its specific binding to a chemoki...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50506122(CHEMBL4531005)
Affinity DataEC50:  4.5nMAssay Description:Non-competitive insurmountable antagonist activity at human CCR5 expressed in human U2OS cell membranes assessed as pEC50 for CCL3-stimulated [35S]GT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50506124(CHEMBL4544504)
Affinity DataEC50:  5nMAssay Description:Non-competitive insurmountable antagonist activity at human CCR5 expressed in human U2OS cell membranes assessed as EC50 for CCL3-stimulated [35S]GTP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50506124(CHEMBL4544504)
Affinity DataEC50:  5nMAssay Description:Non-competitive insurmountable antagonist activity at human CCR5 expressed in human U2OS cell membranes assessed as pEC50 for CCL3-stimulated [35S]GT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50506122(CHEMBL4531005)
Affinity DataEC50:  5nMAssay Description:Non-competitive insurmountable antagonist activity at human CCR5 expressed in human U2OS cell membranes assessed as EC50 for CCL3-stimulated [35S]GTP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50506124(CHEMBL4544504)
Affinity DataEC50:  6nMAssay Description:Non-competitive insurmountable antagonist activity at human CCR5 expressed in human U2OS cell membranes assessed as EC50 for CCL3-stimulated [35S]GTP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50506124(CHEMBL4544504)
Affinity DataEC50:  6.20nMAssay Description:Non-competitive insurmountable antagonist activity at human CCR5 expressed in human U2OS cell membranes assessed as pEC50 for CCL3-stimulated [35S]GT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50088301((E)-N,N-dimethyl-N-(4-(2-p-tolyl-6,7-dihydro-5H-be...)
Affinity DataEC50:  7nMAssay Description:Inhibition of recombinant CYP1B1 (unknown origin) expressed in supersomes coexpressing NADPH-CYP reductase using 7-ethoxyresorufin as substrate after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50506122(CHEMBL4531005)
Affinity DataEC50:  7.20nMAssay Description:Non-competitive insurmountable antagonist activity at human CCR5 expressed in human U2OS cell membranes assessed as pEC50 for CCL3-stimulated [35S]GT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50506122(CHEMBL4531005)
Affinity DataEC50:  7.20nMAssay Description:Non-competitive insurmountable antagonist activity at human CCR5 expressed in human U2OS cell membranes assessed as pEC50 for CCL3-stimulated [35S]GT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM84321(4-Chloro-N-methyl-N-[2-oxo-2-(4-pyridin-2-yl-piper...)
Affinity DataEC50:  7.46nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50506122(CHEMBL4531005)
Affinity DataEC50:  8nMAssay Description:Non-competitive insurmountable antagonist activity at human CCR5 expressed in human U2OS cell membranes assessed as EC50 for CCL3-stimulated [35S]GTP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50506124(CHEMBL4544504)
Affinity DataEC50:  8.90nMAssay Description:Non-competitive insurmountable antagonist activity at human CCR5 expressed in human U2OS cell membranes assessed as pEC50 for CCL3-stimulated [35S]GT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50506124(CHEMBL4544504)
Affinity DataEC50:  9nMAssay Description:Non-competitive insurmountable antagonist activity at human CCR5 expressed in human U2OS cell membranes assessed as EC50 for CCL3-stimulated [35S]GTP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50506122(CHEMBL4531005)
Affinity DataEC50:  9nMAssay Description:Non-competitive insurmountable antagonist activity at human CCR5 expressed in human U2OS cell membranes assessed as EC50 for CCL3-stimulated [35S]GTP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50252441(CHEMBL4061166)
Affinity DataEC50: >10nMAssay Description:Positive allosteric modulation of human CCR5 expressed in HEK293T cells co-expressing CAMYEL assessed as increase in CCL4-induced inhibition of forsk...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50252444(CHEMBL4095900)
Affinity DataEC50: >10nMAssay Description:Positive allosteric modulation of human CCR5 expressed in HEK293T cells co-expressing CAMYEL assessed as increase in CCL4-induced inhibition of forsk...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50252431(CHEMBL4070869)
Affinity DataEC50: >10nMAssay Description:Positive allosteric modulation of human CCR5 expressed in HEK293T cells co-expressing CAMYEL assessed as increase in CCL4-induced inhibition of forsk...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50252435(CHEMBL4091736)
Affinity DataEC50: >10nMAssay Description:Positive allosteric modulation of human CCR5 expressed in HEK293T cells co-expressing CAMYEL assessed as increase in CCL4-induced inhibition of forsk...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50252442(CHEMBL4089329)
Affinity DataEC50: >10nMAssay Description:Positive allosteric modulation of human CCR5 expressed in HEK293T cells co-expressing CAMYEL assessed as increase in CCL4-induced inhibition of forsk...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50252443(CHEMBL4081457)
Affinity DataEC50: >10nMAssay Description:Positive allosteric modulation of human CCR5 expressed in HEK293T cells co-expressing CAMYEL assessed as increase in CCL4-induced inhibition of forsk...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50252440(CHEMBL4069836)
Affinity DataEC50: >10nMAssay Description:Positive allosteric modulation of human CCR5 expressed in HEK293T cells co-expressing CAMYEL assessed as increase in CCL4-induced inhibition of forsk...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50583789(CHEMBL584744)
Affinity DataEC50:  18nMAssay Description:Inhibition of CCR5-mediated HIV-1 Bal entry in human GHOST CCR5 cells assessed as decrease in viral reverse transcriptase activity by measuring [3H]t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM84339(MLS001167316 | N-[4-[2-(2-pyridin-3-yl-1,3-thiazol...)
Affinity DataEC50:  19.6nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50583784(CHEMBL5074744)
Affinity DataEC50:  93nMAssay Description:Inhibition of CCR5-mediated HIV-1 Bal entry in human GHOST CCR5 cells assessed as decrease in viral reverse transcriptase activity by measuring [3H]t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM84203(4-[[1-oxo-2-(5-phenyl-2-tetrazolyl)ethyl]amino]ben...)
Affinity DataEC50:  123nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM84215(4-[[1-oxo-2-[4-(1-pyrrolidinylsulfonyl)phenoxy]eth...)
Affinity DataEC50:  188nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50401347(CHEMBL99384)
Affinity DataEC50:  1.00E+3nMAssay Description:Allosteric modulation at human CCR5 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as [3H]IP3 turnover by liquid scintillation coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50401347(CHEMBL99384)
Affinity DataEC50:  1.00E+3nMAssay Description:Allosteric modulation at human CCR5 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as [3H]IP3 turnover by liquid scintillation coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50205734(1-(6-thiophen-2-yl-pyridazin-3-yl)-piperidine-4-ca...)
Affinity DataEC50:  1.10E+3nMAssay Description:Agonist activity at CCR5 expressed in CHO-K1 cells in aqeuorin based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50401346(CHEMBL316589 | cid_93149)
Affinity DataEC50:  1.80E+3nMAssay Description:Allosteric modulation at human CCR5 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as [3H]IP3 turnover by liquid scintillation coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50401353(CHEMBL2205809)
Affinity DataEC50:  1.90E+3nMAssay Description:Allosteric modulation at human CCR5 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as [3H]IP3 turnover by liquid scintillation coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50205732(1-(3-diethylamino-propylamino)-3-methyl-2-(2-methy...)
Affinity DataEC50:  1.90E+3nMAssay Description:Agonist activity at CCR5 expressed in CHO-K1 cells in aqeuorin based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50401352(CHEMBL2205810)
Affinity DataEC50:  2.00E+3nMAssay Description:Allosteric modulation at human CCR5 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as [3H]IP3 turnover by liquid scintillation coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50401346(CHEMBL316589 | cid_93149)
Affinity DataEC50:  2.00E+3nMAssay Description:Allosteric modulation at human CCR5 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as [3H]IP3 turnover by liquid scintillation coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50401353(CHEMBL2205809)
Affinity DataEC50:  2.00E+3nMAssay Description:Allosteric modulation at human CCR5 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as [3H]IP3 turnover by liquid scintillation coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50205735(CHEMBL219770 | N-(2-methyl-4-((4-methylpiperazin-1...)
Affinity DataEC50:  2.00E+3nMAssay Description:Agonist activity at CCR5 expressed in CHO-K1 cells in aqeuorin based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50401352(CHEMBL2205810)
Affinity DataEC50:  2.20E+3nMAssay Description:Allosteric modulation at human CCR5 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as [3H]IP3 turnover by liquid scintillation coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50401351(CHEMBL2205807)
Affinity DataEC50:  2.30E+3nMAssay Description:Allosteric modulation at human CCR5 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as [3H]IP3 turnover by liquid scintillation coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50252432(CHEMBL4099473)
Affinity DataEC50:  2.47E+3nMAssay Description:Positive allosteric modulation of human CCR5 expressed in HEK293T cells co-expressing CAMYEL assessed as increase in CCL4-induced inhibition of forsk...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50401348(CHEMBL593442)
Affinity DataEC50:  2.51E+3nMAssay Description:Allosteric modulation at human CCR5 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as [3H]IP3 turnover by liquid scintillation coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50401351(CHEMBL2205807)
Affinity DataEC50:  2.51E+3nMAssay Description:Allosteric modulation at human CCR5 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as [3H]IP3 turnover by liquid scintillation coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50401348(CHEMBL593442)
Affinity DataEC50:  2.60E+3nMAssay Description:Allosteric modulation at human CCR5 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as [3H]IP3 turnover by liquid scintillation coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50205736(2-(4-benzyl-5-(2-(piperidin-1-yl)ethyl)-4H-1,2,4-t...)
Affinity DataEC50:  3.00E+3nMAssay Description:Agonist activity at CCR5 expressed in CHO-K1 cells in aqeuorin based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)
Affinity DataEC50:  4.90E+3nMAssay Description:Allosteric modulation at human CCR5 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as [3H]IP3 turnover by liquid scintillation coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)
Affinity DataEC50:  5.01E+3nMAssay Description:Allosteric modulation at human CCR5 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as [3H]IP3 turnover by liquid scintillation coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50401343(CHEMBL2205801)
Affinity DataEC50:  1.00E+4nMAssay Description:Allosteric modulation at human CCR5 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as [3H]IP3 turnover by liquid scintillation coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50401343(CHEMBL2205801)
Affinity DataEC50:  1.00E+4nMAssay Description:Allosteric modulation at human CCR5 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as [3H]IP3 turnover by liquid scintillation coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50255479(CHEMBL4067429)
Affinity DataEC50: >1.00E+4nMAssay Description:Antagonist activity at TEV protease cleavage site linked GAL4-VP16-fused recombinant human CXCR2 expressed in cells assessed as inhibition of TEV pro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50401350(CHEMBL101165)
Affinity DataEC50:  1.10E+4nMAssay Description:Allosteric modulation at human CCR5 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as [3H]IP3 turnover by liquid scintillation coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 71 total ) | Next | Last >>
Jump to: