Compile Data Set for Download or QSAR
maximum 50k data
Found 249 of ic50 data for polymerid = 1808
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Colorado Mesa University

Curated by ChEMBL
LigandPNGBDBM50267199(CHEMBL4079583)
Affinity DataIC50:  100nMAssay Description:Inhibition of human MetAP1More data for this Ligand-Target Pair
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Colorado Mesa University

Curated by ChEMBL
LigandPNGBDBM50435227(CHEMBL2392772)
Affinity DataIC50:  360nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Colorado Mesa University

Curated by ChEMBL
LigandPNGBDBM17589((2S,3R)-3-amino-5-(ethylsulfanyl)-2-hydroxy-N-[(1S...)
Affinity DataIC50:  370nMAssay Description:Inhibitory activity against human methionine aminopeptidase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Colorado Mesa University

Curated by ChEMBL
LigandPNGBDBM17589((2S,3R)-3-amino-5-(ethylsulfanyl)-2-hydroxy-N-[(1S...)
Affinity DataIC50:  370nMpH: 7.4 T: 2°CAssay Description:A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase activity by monitoring the production of free methionine with L...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Colorado Mesa University

Curated by ChEMBL
LigandPNGBDBM17847(CHEMBL327579 | pyridine-2-carboxylic acid inhibito...)
Affinity DataIC50:  400nMAssay Description:Inhibition of human MetAP1More data for this Ligand-Target Pair
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Colorado Mesa University

Curated by ChEMBL
LigandPNGBDBM50435224(CHEMBL2392893)
Affinity DataIC50:  600nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Colorado Mesa University

Curated by ChEMBL
LigandPNGBDBM50435217(CHEMBL2392900)
Affinity DataIC50:  600nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Colorado Mesa University

Curated by ChEMBL
LigandPNGBDBM50267193(CHEMBL4078211)
Affinity DataIC50:  700nMAssay Description:Inhibition of human MetAP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Colorado Mesa University

Curated by ChEMBL
LigandPNGBDBM50433375(CHEMBL472879 | GNF-Pf-359)
Affinity DataIC50:  700nMAssay Description:Inhibition of HuMetAP1 using Met-Pro-pNA as substrate by spectrophotometer based analysisMore data for this Ligand-Target Pair
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Colorado Mesa University

Curated by ChEMBL
LigandPNGBDBM50295174(Bengamide A | CHEMBL256279)
Affinity DataIC50:  700nMAssay Description:Inhibition of human MetAP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Colorado Mesa University

Curated by ChEMBL
LigandPNGBDBM50435219(CHEMBL2392898)
Affinity DataIC50:  800nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Colorado Mesa University

Curated by ChEMBL
LigandPNGBDBM50435218(CHEMBL2392899)
Affinity DataIC50:  800nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Colorado Mesa University

Curated by ChEMBL
LigandPNGBDBM50435226(CHEMBL2392891)
Affinity DataIC50:  800nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Colorado Mesa University

Curated by ChEMBL
LigandPNGBDBM50433375(CHEMBL472879 | GNF-Pf-359)
Affinity DataIC50:  860nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Colorado Mesa University

Curated by ChEMBL
LigandPNGBDBM50435229(CHEMBL2392771)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Colorado Mesa University

Curated by ChEMBL
LigandPNGBDBM50497538(CHEMBL3337748)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of N-terminal poly-His-tagged human MetAP-1 expressed in Escherichia coli BL21(DE3) incubated for 30 mins before MGMM substrate addition b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Colorado Mesa University

Curated by ChEMBL
LigandPNGBDBM50435225(CHEMBL2392892)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Colorado Mesa University

Curated by ChEMBL
LigandPNGBDBM50435223(CHEMBL2392894)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Colorado Mesa University

Curated by ChEMBL
LigandPNGBDBM50435228(CHEMBL460432)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Colorado Mesa University

Curated by ChEMBL
LigandPNGBDBM50435220(CHEMBL2392897)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Colorado Mesa University

Curated by ChEMBL
LigandPNGBDBM50141738((2S,3R)-3-Amino-5-ethylsulfanyl-2-hydroxy-pentanoi...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibitory activity against human methionine aminopeptidase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Colorado Mesa University

Curated by ChEMBL
LigandPNGBDBM50141691((1S,2R)-3-Amino-5-ethylsulfanyl-2-hydroxy-pentanoi...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibitory activity against human methionine aminopeptidase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Colorado Mesa University

Curated by ChEMBL
LigandPNGBDBM50435222(CHEMBL2392895)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Colorado Mesa University

Curated by ChEMBL
LigandPNGBDBM50141693((S)-3-Amino-2-hydroxy-4-isobutylsulfanyl-N-phenoxy...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibitory activity against human methionine aminopeptidase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Colorado Mesa University

Curated by ChEMBL
LigandPNGBDBM17847(CHEMBL327579 | pyridine-2-carboxylic acid inhibito...)
Affinity DataIC50:  1.50E+3nMpH: 7.5 T: 2°CAssay Description:The MetAP reaction with Co2+ as a cofactor is coupled to a prolyl aminopeptidase (ProAP) using Met-Pro-p-nitroanilide as substrate. MetAP-catalyzed c...More data for this Ligand-Target Pair
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Colorado Mesa University

Curated by ChEMBL
LigandPNGBDBM50435231(CHEMBL2392769)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Colorado Mesa University

Curated by ChEMBL
LigandPNGBDBM50141746((S)-3-Amino-2-hydroxy-N-((S)-1-naphthalen-1-yl-eth...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibitory activity against human methionine aminopeptidase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Colorado Mesa University

Curated by ChEMBL
LigandPNGBDBM50435221(CHEMBL2392896)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Colorado Mesa University

Curated by ChEMBL
LigandPNGBDBM50141713((S)-3-Amino-2-hydroxy-N-phenoxy-4-propylsulfanyl-b...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibitory activity against human methionine aminopeptidase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Colorado Mesa University

Curated by ChEMBL
LigandPNGBDBM68281(Bengamide A)
Affinity DataIC50:  1.90E+3nMAssay Description:The determined effects of seven bengamide analogs on the enzymatic activity of both recombinated human MetAP1 and MetAP2 in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Colorado Mesa University

Curated by ChEMBL
LigandPNGBDBM17847(CHEMBL327579 | pyridine-2-carboxylic acid inhibito...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of methionine aminopeptidase 1More data for this Ligand-Target Pair
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Colorado Mesa University

Curated by ChEMBL
LigandPNGBDBM50295174(Bengamide A | CHEMBL256279)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of methionine aminopeptidase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Colorado Mesa University

Curated by ChEMBL
LigandPNGBDBM50433377(CHEMBL2375628)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Colorado Mesa University

Curated by ChEMBL
LigandPNGBDBM17590((2S,3S)-3-amino-2-hydroxy-4-[(2-methylpropyl)sulfa...)
Affinity DataIC50:  2.20E+3nMpH: 7.4 T: 2°CAssay Description:A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase activity by monitoring the production of free methionine with L...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Colorado Mesa University

Curated by ChEMBL
LigandPNGBDBM17590((2S,3S)-3-amino-2-hydroxy-4-[(2-methylpropyl)sulfa...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibitory activity against human methionine aminopeptidase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Colorado Mesa University

Curated by ChEMBL
LigandPNGBDBM68286(Bengamide N | Bengamide O)
Affinity DataIC50:  2.70E+3nMAssay Description:The determined effects of seven bengamide analogs on the enzymatic activity of both recombinated human MetAP1 and MetAP2 in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Colorado Mesa University

Curated by ChEMBL
LigandPNGBDBM17849(3-(2,2-dimethylpropanamido)-N-(1,3-thiazol-2-yl)py...)
Affinity DataIC50:  2.90E+3nMpH: 7.5 T: 2°CAssay Description:The MetAP reaction with Co2+ as a cofactor is coupled to a prolyl aminopeptidase (ProAP) using Met-Pro-p-nitroanilide as substrate. MetAP-catalyzed c...More data for this Ligand-Target Pair
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Colorado Mesa University

Curated by ChEMBL
LigandPNGBDBM50295173(Bengamide O | CHEMBL539894)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of methionine aminopeptidase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Colorado Mesa University

Curated by ChEMBL
LigandPNGBDBM50267195(CHEMBL4061080)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human MetAP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Colorado Mesa University

Curated by ChEMBL
LigandPNGBDBM50497521(CHEMBL3337749)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of N-terminal poly-His-tagged human MetAP-1 expressed in Escherichia coli BL21(DE3) incubated for 30 mins before MGMM substrate addition b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Colorado Mesa University

Curated by ChEMBL
LigandPNGBDBM17850(3-(3-phenylpropanamido)-N-(1,3-thiazol-2-yl)pyridi...)
Affinity DataIC50:  3.50E+3nMpH: 7.5 T: 2°CAssay Description:The MetAP reaction with Co2+ as a cofactor is coupled to a prolyl aminopeptidase (ProAP) using Met-Pro-p-nitroanilide as substrate. MetAP-catalyzed c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Colorado Mesa University

Curated by ChEMBL
LigandPNGBDBM50497528(CHEMBL3337742)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of N-terminal poly-His-tagged human MetAP-1 expressed in Escherichia coli BL21(DE3) incubated for 30 mins before MGMM substrate addition b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Colorado Mesa University

Curated by ChEMBL
LigandPNGBDBM50398199(CHEMBL1738934)
Affinity DataIC50:  3.59E+3nMAssay Description:Inhibition of Mn(II) form of human methionine aminopeptidase1 expressed in Escherichia coli at 100 mMMore data for this Ligand-Target Pair
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Colorado Mesa University

Curated by ChEMBL
LigandPNGBDBM50435237(CHEMBL2392764)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Colorado Mesa University

Curated by ChEMBL
LigandPNGBDBM50141708((R)-3-Amino-2-hydroxy-5-isopropylsulfanyl-pentanoi...)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibitory activity against human methionine aminopeptidase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Colorado Mesa University

Curated by ChEMBL
LigandPNGBDBM50141697(3-Amino-2-(S)-hydroxy-4-propylsulfanyl-butyric aci...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibitory activity against human methionine aminopeptidase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Colorado Mesa University

Curated by ChEMBL
LigandPNGBDBM50398196(CHEMBL2181034)
Affinity DataIC50:  5.14E+3nMAssay Description:Inhibition of Mn(II) form of human methionine aminopeptidase1 expressed in Escherichia coli at 100 mMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Colorado Mesa University

Curated by ChEMBL
LigandPNGBDBM50141699((2S,3R)-3-Amino-4-cyclohexyl-2-hydroxy-N-(1-naphth...)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibitory activity against human methionine aminopeptidase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Colorado Mesa University

Curated by ChEMBL
LigandPNGBDBM68285(Bengamide M)
Affinity DataIC50:  5.40E+3nMAssay Description:The determined effects of seven bengamide analogs on the enzymatic activity of both recombinated human MetAP1 and MetAP2 in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Colorado Mesa University

Curated by ChEMBL
LigandPNGBDBM50398197(CHEMBL1738933)
Affinity DataIC50:  5.58E+3nMAssay Description:Inhibition of Mn(II) form of human methionine aminopeptidase1 expressed in Escherichia coli at 100 mMMore data for this Ligand-Target Pair
Displayed 1 to 50 (of 249 total ) | Next | Last >>
Jump to: