Compile Data Set for Download or QSAR
maximum 50k data
Found 1056 of ic50 data for polymerid = 2129,9124
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Warwick

Curated by ChEMBL
LigandPNGBDBM50149598(CHEMBL3770679)
Affinity DataIC50:  0.0295nMAssay Description:Agonist activity at human Adenosine A1 receptor transfected in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP production after 30 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Warwick

Curated by ChEMBL
LigandPNGBDBM474233(5-[5-amino-7-(4-fluorophenyl)-2-[(3-fluoropyrid in...)
Affinity DataIC50:  0.100nMAssay Description:Binding affinity and specificities of the compounds against different subtype of human adenosine receptors (hA1, hA2A, hA2B and hA3) were characteriz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Warwick

Curated by ChEMBL
LigandPNGBDBM474233(5-[5-amino-7-(4-fluorophenyl)-2-[(3-fluoropyrid in...)
Affinity DataIC50:  0.100nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Warwick

Curated by ChEMBL
LigandPNGBDBM50375517(CHEMBL411245)
Affinity DataIC50:  0.120nMAssay Description:Agonist activity at adenosine A1 receptor assessed as inhibition of isoproterenol-stimulated cAMP accumulation in DDT1MF-2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Warwick

Curated by ChEMBL
LigandPNGBDBM50517299(CHEMBL4533718)
Affinity DataIC50:  0.140nMAssay Description:Agonist activity at human A1A adenosine receptor expressed in HEK cells assessed as inhibition of forskolin-stimulated cAMP production after 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Warwick

Curated by ChEMBL
LigandPNGBDBM474222(5-(5-amino-2-(2,6-difluorobenzyl)-7-(4- fluorophen...)
Affinity DataIC50:  0.200nMAssay Description:Binding affinity and specificities of the compounds against different subtype of human adenosine receptors (hA1, hA2A, hA2B and hA3) were characteriz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Warwick

Curated by ChEMBL
LigandPNGBDBM474222(5-(5-amino-2-(2,6-difluorobenzyl)-7-(4- fluorophen...)
Affinity DataIC50:  0.200nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Warwick

Curated by ChEMBL
LigandPNGBDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)
Affinity DataIC50:  0.209nMAssay Description:Agonist activity at human Adenosine A1 receptor transfected in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP production after 30 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Janssen Research Foundation

Curated by ChEMBL
LigandPNGBDBM50403738(CHEMBL351483)
Affinity DataIC50:  0.214nMAssay Description:Binding affinity at human Alpha-2A adrenergic receptor in CHO cells by [3H]rauwolscine (1 nM) displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Janssen Research Foundation

Curated by ChEMBL
LigandPNGBDBM50403753(CHEMBL162682)
Affinity DataIC50:  0.240nMAssay Description:Binding affinity at human Alpha-2A adrenergic receptor in CHO cells by [3H]rauwolscine (1 nM) displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Janssen Research Foundation

Curated by ChEMBL
LigandPNGBDBM50403755(CHEMBL163190)
Affinity DataIC50:  0.288nMAssay Description:Binding affinity at human Alpha-2A adrenergic receptor in CHO cells by [3H]rauwolscine (1 nM) displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Janssen Research Foundation

Curated by ChEMBL
LigandPNGBDBM50403745(CHEMBL162490)
Affinity DataIC50:  0.295nMAssay Description:Binding affinity at human Alpha-2A adrenergic receptor in CHO cells by [3H]rauwolscine (1 nM) displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Warwick

Curated by ChEMBL
LigandPNGBDBM50375516(CHEMBL258759)
Affinity DataIC50:  0.300nMAssay Description:Agonist activity at adenosine A1 receptor assessed as inhibition of isoproterenol-stimulated cAMP accumulation in DDT1MF-2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Janssen Research Foundation

Curated by ChEMBL
LigandPNGBDBM50403748(CHEMBL162232)
Affinity DataIC50:  0.339nMAssay Description:Binding affinity at human Alpha-2A adrenergic receptor in CHO cells by [3H]rauwolscine (1 nM) displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Janssen Research Foundation

Curated by ChEMBL
LigandPNGBDBM50403752(CHEMBL162370)
Affinity DataIC50:  0.347nMAssay Description:Binding affinity at human Alpha-2A adrenergic receptor in CHO cells by [3H]rauwolscine (1 nM) displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Janssen Research Foundation

Curated by ChEMBL
LigandPNGBDBM50403740(CHEMBL165350)
Affinity DataIC50:  0.355nMAssay Description:Binding affinity at human Alpha-2A adrenergic receptor in CHO cells by [3H]rauwolscine (1 nM) displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Warwick

Curated by ChEMBL
LigandPNGBDBM50385957(CHEMBL2042297)
Affinity DataIC50:  0.360nMAssay Description:Agonist activity at human adenosine A1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Warwick

Curated by ChEMBL
LigandPNGBDBM50149597(CHEMBL3771184)
Affinity DataIC50:  0.398nMAssay Description:Agonist activity at human Adenosine A1 receptor transfected in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP production after 30 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Janssen Research Foundation

Curated by ChEMBL
LigandPNGBDBM50403742(CHEMBL165796)
Affinity DataIC50:  0.447nMAssay Description:Binding affinity at human Alpha-2A adrenergic receptor in CHO cells by [3H]rauwolscine (1 nM) displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Warwick

Curated by ChEMBL
LigandPNGBDBM21173(1,3-dipropyl-8-cyclopentylxanthine | 8-cyclopentyl...)
Affinity DataIC50:  0.5nMAssay Description:Displacement of [3H]DPCPX from human recombinant adenosine receptor A1 expressed in CHO cells measured after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Warwick

Curated by ChEMBL
LigandPNGBDBM21173(1,3-dipropyl-8-cyclopentylxanthine | 8-cyclopentyl...)
Affinity DataIC50:  0.5nMAssay Description:Displacement of [3H]DPCPX from human recombinant adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Warwick

Curated by ChEMBL
LigandPNGBDBM50085658((2R,3R,4S,5R)-2-(2-Chloro-6-cyclopentylamino-purin...)
Affinity DataIC50:  0.501nMAssay Description:Agonist activity at human Adenosine A1 receptor transfected in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP production after 30 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Janssen Research Foundation

Curated by ChEMBL
LigandPNGBDBM50403744(LUSAPERIDONE)
Affinity DataIC50:  0.550nMAssay Description:Binding affinity at human Alpha-2A adrenergic receptor in CHO cells by [3H]rauwolscine (1 nM) displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Janssen Research Foundation

Curated by ChEMBL
LigandPNGBDBM50403739(CHEMBL163247)
Affinity DataIC50:  0.589nMAssay Description:Binding affinity at human Alpha-2A adrenergic receptor in CHO cells by [3H]rauwolscine (1 nM) displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Warwick

Curated by ChEMBL
LigandPNGBDBM50327343(2-(4-(8-fluoroquinoxalin-6-yl)-3-methyl-1-o-tolyl-...)
Affinity DataIC50:  0.600nMAssay Description:Antagonist activity at adenosine A1 receptor by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Janssen Research Foundation

Curated by ChEMBL
LigandPNGBDBM50403750(CHEMBL351200)
Affinity DataIC50:  0.603nMAssay Description:Binding affinity at human Alpha-2A adrenergic receptor in CHO cells by [3H]rauwolscine (1 nM) displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Warwick

Curated by ChEMBL
LigandPNGBDBM392076(US10301272, Example 7/9)
Affinity DataIC50:  0.610nMAssay Description:Displacement of [3H]-DPCPX from human recombinant adenosine A1 receptor after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Warwick

Curated by ChEMBL
LigandPNGBDBM50149594(CHEMBL3771208)
Affinity DataIC50:  0.676nMAssay Description:Agonist activity at human Adenosine A1 receptor transfected in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP production after 30 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Janssen Research Foundation

Curated by ChEMBL
LigandPNGBDBM50403747(CHEMBL162826)
Affinity DataIC50:  0.692nMAssay Description:Binding affinity at human Alpha-2A adrenergic receptor in CHO cells by [3H]rauwolscine (1 nM) displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Warwick

Curated by ChEMBL
LigandPNGBDBM474230(5-(5-amino-7-(4-fluorophenyl)-2-((3-fluoropyrid in...)
Affinity DataIC50:  0.800nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Warwick

Curated by ChEMBL
LigandPNGBDBM474237(5-(5-amino-7-(3-chlorophenyl)-2-((3-fluoropyrid in...)
Affinity DataIC50:  0.800nMAssay Description:Binding affinity and specificities of the compounds against different subtype of human adenosine receptors (hA1, hA2A, hA2B and hA3) were characteriz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Warwick

Curated by ChEMBL
LigandPNGBDBM474237(5-(5-amino-7-(3-chlorophenyl)-2-((3-fluoropyrid in...)
Affinity DataIC50:  0.800nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Warwick

Curated by ChEMBL
LigandPNGBDBM474230(5-(5-amino-7-(4-fluorophenyl)-2-((3-fluoropyrid in...)
Affinity DataIC50:  0.800nMAssay Description:Binding affinity and specificities of the compounds against different subtype of human adenosine receptors (hA1, hA2A, hA2B and hA3) were characteriz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Janssen Research Foundation

Curated by ChEMBL
LigandPNGBDBM50403754(CHEMBL164612)
Affinity DataIC50:  0.891nMAssay Description:Binding affinity at human Alpha-2A adrenergic receptor in CHO cells by [3H]rauwolscine (1 nM) displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Warwick

Curated by ChEMBL
LigandPNGBDBM50375515(CHEMBL410288)
Affinity DataIC50:  0.900nMAssay Description:Agonist activity at adenosine A1 receptor assessed as inhibition of isoproterenol-stimulated cAMP accumulation in DDT1MF-2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Warwick

Curated by ChEMBL
LigandPNGBDBM479527(3-amino-5-(4-fluorophenyl)-6-(3- methyl-3H-benzo[d...)
Affinity DataIC50:  0.900nMAssay Description:Binding affinity and specificalities of the compounds against different subtype of human adenosine receptors (hA1, hA2a, hA2b, and hA3) were characte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Warwick

Curated by ChEMBL
LigandPNGBDBM479527(3-amino-5-(4-fluorophenyl)-6-(3- methyl-3H-benzo[d...)
Affinity DataIC50:  0.900nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Warwick

Curated by ChEMBL
LigandPNGBDBM474221(8-(2,6-dimethylpyridin-4-yl)-7-(4-fluoropheny1)- 2...)
Affinity DataIC50:  1.10nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Warwick

Curated by ChEMBL
LigandPNGBDBM474221(8-(2,6-dimethylpyridin-4-yl)-7-(4-fluoropheny1)- 2...)
Affinity DataIC50:  1.10nMAssay Description:Binding affinity and specificities of the compounds against different subtype of human adenosine receptors (hA1, hA2A, hA2B and hA3) were characteriz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Warwick

Curated by ChEMBL
LigandPNGBDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)
Affinity DataIC50:  1.10nMAssay Description:Antagonist activity at wild type A1R (unknown origin) expressed in CHO-K1 cells assessed as inhibition of NECA reduced forskolin stimulated cAMP accu...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Janssen Research Foundation

Curated by ChEMBL
LigandPNGBDBM50403746(CHEMBL162147)
Affinity DataIC50:  1.20nMAssay Description:Binding affinity at human Alpha-2A adrenergic receptor in CHO cells by [3H]rauwolscine (1 nM) displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Warwick

Curated by ChEMBL
LigandPNGBDBM50085658((2R,3R,4S,5R)-2-(2-Chloro-6-cyclopentylamino-purin...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of cAMP formation in CHO cells expressing adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Warwick

Curated by ChEMBL
LigandPNGBDBM50327327(2-(4-(4-fluorophenyl)-3-methyl-1-o-tolyl-1H-pyrazo...)
Affinity DataIC50:  1.39nMAssay Description:Antagonist activity at adenosine A1 receptor by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Warwick

Curated by ChEMBL
LigandPNGBDBM474238(5-(5-amino-2-((3-fluoropyridin-2-yl)methyl)-7- (3-...)
Affinity DataIC50:  1.40nMAssay Description:Binding affinity and specificities of the compounds against different subtype of human adenosine receptors (hA1, hA2A, hA2B and hA3) were characteriz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Warwick

Curated by ChEMBL
LigandPNGBDBM474238(5-(5-amino-2-((3-fluoropyridin-2-yl)methyl)-7- (3-...)
Affinity DataIC50:  1.40nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Warwick

Curated by ChEMBL
LigandPNGBDBM50591171(CHEMBL5174600)
Affinity DataIC50:  1.40nMAssay Description:Antagonist activity at wild type A1R (unknown origin) expressed in CHO-K1 cells assessed as inhibition of NECA reduced forskolin stimulated cAMP accu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Warwick

Curated by ChEMBL
LigandPNGBDBM474234(5-(5-amino-2-((3-fluoropyridin-2-yl)methyl)-7- (4-...)
Affinity DataIC50:  1.70nMAssay Description:Binding affinity and specificities of the compounds against different subtype of human adenosine receptors (hA1, hA2A, hA2B and hA3) were characteriz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Janssen Research Foundation

Curated by ChEMBL
LigandPNGBDBM50403749(CHEMBL165181)
Affinity DataIC50:  1.70nMAssay Description:Binding affinity at human Alpha-2A adrenergic receptor in CHO cells by [3H]rauwolscine (1 nM) displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Warwick

Curated by ChEMBL
LigandPNGBDBM474234(5-(5-amino-2-((3-fluoropyridin-2-yl)methyl)-7- (4-...)
Affinity DataIC50:  1.70nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Warwick

Curated by ChEMBL
LigandPNGBDBM50225877((2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-((R)-tetrahyd...)
Affinity DataIC50:  1.90nMAssay Description:Agonist activity at adenosine A1 receptor expressed in DDT1 MF2 cells assessed as inhibition of (-)-isoproterenol-stimulated cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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