Compile Data Set for Download or QSAR
maximum 50k data
Found 32 of ic50 data for polymerid = 2891,4871,4872,50000911,50001287
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50011477(ALBACONAZOLE | UR-9825)
Affinity DataIC50:  1nMAssay Description:Inhibition of Trypanosoma cruzi Sterol 14-alpha demethylaseMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Panjab University

Curated by ChEMBL
LigandPNGBDBM8610(1-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imi...)
Affinity DataIC50:  14nMAssay Description:Inhibition of recombinant Trypanosoma cruzi Tulahuen strain CYP51 expressed in Escherichia coli JM109More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50545214(CHEMBL4633298)
Affinity DataIC50:  41nMAssay Description:Inhibition of Trypanosoma cruzi CYP51More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLanosterol 14-alpha demethylase(Rattus norvegicus)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)
Affinity DataIC50:  47nMAssay Description:Inhibition of Progesterone 21-hydroxylase cytochrome P450 21More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50181473(4-(4-(4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)met...)
Affinity DataIC50:  48nMAssay Description:Inhibition of recombinant Trypanosoma cruzi Tulahuen CYP51 expressed in Escherichia coli JM109 cell membranes assessed as inhibition of microbe growt...More data for this Ligand-Target Pair
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50545214(CHEMBL4633298)
Affinity DataIC50:  52nMAssay Description:Inhibition of Trypanosoma cruzi CYP51More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50545214(CHEMBL4633298)
Affinity DataIC50:  52nMAssay Description:Inhibition of Trypanosoma cruzi CYP51More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50545219(CHEMBL4646274)
Affinity DataIC50:  53nMAssay Description:Inhibition of Trypanosoma cruzi CYP51More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50545216(CHEMBL4638031)
Affinity DataIC50:  77nMAssay Description:Inhibition of Trypanosoma cruzi CYP51More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50458303(CHEMBL4208391)
Affinity DataIC50:  100nMAssay Description:Inhibition of recombinant Trypanosoma cruzi Tulahuen CYP51 expressed in Escherichia coli JM109 cell membranes assessed as inhibition of microbe growt...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol 14-alpha demethylase(Rattus norvegicus)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)
Affinity DataIC50:  119nMAssay Description:Inhibition of lanosterol 14 alpha-demethylase cytochrome P450 51AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol 14-alpha demethylase(Rattus norvegicus)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50046560(17-(1,5-Dimethyl-hexyl)-14-(1-hydroxy-ethyl)-4,4,1...)
Affinity DataIC50:  300nMAssay Description:Inhibition rat liver microsome cytochrome P450DMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Panjab University

Curated by ChEMBL
LigandPNGBDBM25817(2-(2,4-difluorophenyl)-1,3-bis(1H-1,2,4-triazol-1-...)
Affinity DataIC50:  880nMAssay Description:Inhibition of recombinant Trypanosoma cruzi Tulahuen CYP51 expressed in Escherichia coli JM109 cell membranes assessed as inhibition of microbe growt...More data for this Ligand-Target Pair
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50181473(4-(4-(4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)met...)
Affinity DataIC50:  880nMAssay Description:Inhibition of recombinant Trypanosoma cruzi Tulahuen strain CYP51 expressed in Escherichia coli JM109More data for this Ligand-Target Pair
TargetLanosterol 14-alpha demethylase(Rattus norvegicus)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50004441((2R,4R)-ketoconazole | 1-acetyl-4-(4-{[(2R,4R)-2-(...)
Affinity DataIC50:  1.37E+3nMAssay Description:Inhibition of lanosterol 14 alpha-demethylase cytochrome P450 51AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol 14-alpha demethylase(Rattus norvegicus)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50004442((2S,4S)-ketoconazole | 1-acetyl-4-(4-{[(2S,4S)-2-(...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of lanosterol 14 alpha-demethylase cytochrome P450 51AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol 14-alpha demethylase(Rattus norvegicus)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50046560(17-(1,5-Dimethyl-hexyl)-14-(1-hydroxy-ethyl)-4,4,1...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition rat liver microsome cytochrome P450DMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol 14-alpha demethylase(Rattus norvegicus)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50046560(17-(1,5-Dimethyl-hexyl)-14-(1-hydroxy-ethyl)-4,4,1...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition rat liver microsome cytochrome P450DMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol 14-alpha demethylase(Rattus norvegicus)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50046561(1-[17-(1,5-Dimethyl-hexyl)-3-hydroxy-4,4,10,13-tet...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition rat liver microsome cytochrome P450DMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50545213(CHEMBL4637098)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of Trypanosoma cruzi CYP51More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbon storage regulator(Escherichia coli (strain K12))
Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50596605(CHEMBL5201187)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of 5'-AGACAAGGAUGU[flc] mRNA binding to biotinylated His6-tagged Escherichia coli CsrA measured by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCarbon storage regulator(Escherichia coli (strain K12))
Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50596603(CHEMBL5174765)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of 5'-AGACAAGGAUGU[flc] mRNA binding to biotinylated His6-tagged Escherichia coli CsrA measured by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCarbon storage regulator(Escherichia coli (strain K12))
Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50596604(CHEMBL5190066)
Affinity DataIC50:  6.80E+3nMAssay Description:Inhibition of 5'-AGACAAGGAUGU[flc] mRNA binding to biotinylated His6-tagged Escherichia coli CsrA measured by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLanosterol 14-alpha demethylase(Rattus norvegicus)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50046561(1-[17-(1,5-Dimethyl-hexyl)-3-hydroxy-4,4,10,13-tet...)
Affinity DataIC50:  9.10E+3nMAssay Description:Inhibition rat liver microsome cytochrome P450DMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50463655(CHEMBL546608 | TCMDC-124726)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi CYP51More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbon storage regulator(Escherichia coli (strain K12))
Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50596606(CHEMBL5203462)
Affinity DataIC50:  4.81E+4nMAssay Description:Inhibition of 5'-AGACAAGGAUGU[flc] mRNA binding to biotinylated His6-tagged Escherichia coli CsrA measured by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50510996(CHEMBL3105168)
Affinity DataIC50:  4.90E+4nMAssay Description:Inhibition of Trypanosoma cruzi Tulahuen C4 CYP51 expressed in Escherichia coli HMS174 using [3H]-sterol as substrate in presence of NADPH by reverse...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbon storage regulator(Escherichia coli (strain K12))
Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50596607(CHEMBL5184463)
Affinity DataIC50:  5.16E+4nMAssay Description:Inhibition of 5'-AGACAAGGAUGU[flc] mRNA binding to biotinylated His6-tagged Escherichia coli CsrA measured by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLanosterol 14-alpha demethylase(Rattus norvegicus)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50213698((1R,3aS,3bR,5aS,7S,9aS,9bS,11aR,E)-3,10-dihydroxy-...)
Affinity DataIC50:  5.50E+4nMAssay Description:Inhibition of rat liver LDMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbon storage regulator(Escherichia coli (strain K12))
Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50596608(CHEMBL5183553)
Affinity DataIC50:  8.34E+4nMAssay Description:Inhibition of 5'-AGACAAGGAUGU[flc] mRNA binding to biotinylated His6-tagged Escherichia coli CsrA measured by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCarbon storage regulator(Escherichia coli (strain K12))
Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50596602(CHEMBL5192634)
Affinity DataIC50:  1.82E+5nMAssay Description:Inhibition of 5'-AGACAAGGAUGU[flc] mRNA binding to biotinylated His6-tagged Escherichia coli CsrA measured by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50510997(CHEMBL4448813)
Affinity DataIC50:  4.87E+5nMAssay Description:Inhibition of Trypanosoma cruzi Tulahuen C4 CYP51 expressed in Escherichia coli HMS174 using [3H]-sterol as substrate in presence of NADPH by reverse...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed