Compile Data Set for Download or QSAR
maximum 50k data
Found 30 of ic50 data for polymerid = 49000070,49000071,49000072,49000073,49000076,49000077
Target5-hydroxytryptamine receptor 3A(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM85330(CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...)
Affinity DataIC50:  0.160nMAssay Description:Binding affinity to rat 5HT3A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)
Affinity DataIC50:  0.180nMAssay Description:Binding affinity to rat 5HT3A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50060686(4-(4-Methyl-piperazin-1-yl)-pyrrolo[1,2-a]quinolin...)
Affinity DataIC50:  0.370nMAssay Description:Displacement of [3H]-BRL 43694 from 5-HT3 receptor in rat cortex membrane incubated for 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50081981(4-(4-Benzyl-piperazin-1-yl)-9-methyl-pyrrolo[1,2-a...)
Affinity DataIC50:  8.80nMAssay Description:Displacement of [3H]LY278584 from 5HT3 receptor in rat cortical homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50081974(4-(4-Benzyl-piperazin-1-yl)-7-fluoro-pyrrolo[1,2-a...)
Affinity DataIC50:  13nMAssay Description:Displacement of [3H]LY278584 from 5HT3 receptor in rat cortical homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50304334(3alpha-(1'-Methyl-2'-Indolecarbonyloxy)-tropane | ...)
Affinity DataIC50:  18nMAssay Description:Displacement of [3H]granisectron from 5HT3 receptor in Wistar rat forebrainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50304335(3alpha-(1'-Methyl-2'-Indolecarbonyloxy)-nortropane...)
Affinity DataIC50:  25nMAssay Description:Displacement of [3H]granisectron from 5HT3 receptor in Wistar rat forebrainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50304333(3alpha-(2'-Indolecarbonyloxy)-nortropane | CHEMBL5...)
Affinity DataIC50:  32nMAssay Description:Displacement of [3H]granisectron from 5HT3 receptor in Wistar rat forebrainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(GUINEA PIG)
European Research Centre For Drug Discovery And Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50299660(7-fluoro-4-(4-((3H-imidazol-4-yl)methyl)piperazin-...)
Affinity DataIC50:  270nMAssay Description:Antagonist activity at 5HT3 receptor in spontaneously beating guinea pig right atrium assessed as inhibition of serotonin-induced maximum response by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(GUINEA PIG)
European Research Centre For Drug Discovery And Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50599900(CHEMBL5190788)
Affinity DataIC50:  300nMAssay Description:Antagonist activity at 5-HT3 receptor in guinea-pig ileum assessed as inhibition of 5HT-induced contractionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 3A(GUINEA PIG)
European Research Centre For Drug Discovery And Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50599911(CHEMBL5205697)
Affinity DataIC50:  1.00E+3nMAssay Description:Antagonist activity at 5-HT3 receptor in guinea-pig ileum assessed as inhibition of 5HT-induced contractionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 3A(GUINEA PIG)
European Research Centre For Drug Discovery And Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50599913(CHEMBL5200023)
Affinity DataIC50:  1.00E+3nMAssay Description:Antagonist activity at 5-HT3 receptor in guinea-pig ileum assessed as inhibition of 5HT-induced contractionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 3A(GUINEA PIG)
European Research Centre For Drug Discovery And Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50258292(2-(4-(7-fluoropyrrolo[1,2-a]quinoxalin-4-yl)pipera...)
Affinity DataIC50:  1.88E+3nMAssay Description:Antagonist activity at 5HT3 receptor in spontaneously beating guinea pig right atrium assessed as inhibition of serotonin-induced maximum response by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(GUINEA PIG)
European Research Centre For Drug Discovery And Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50258292(2-(4-(7-fluoropyrrolo[1,2-a]quinoxalin-4-yl)pipera...)
Affinity DataIC50:  1.91E+3nMAssay Description:Antagonist activity at 5HT3 receptor in spontaneously beating guinea pig right atrium assessed as inhibition of serotonin-induced maximum response by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(GUINEA PIG)
European Research Centre For Drug Discovery And Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50299665(7-hydroxy-4-(4-((3H-imidazol-4-yl)methyl)piperazin...)
Affinity DataIC50:  2.63E+3nMAssay Description:Antagonist activity at 5HT3 receptor in spontaneously beating guinea pig right atrium assessed as inhibition of serotonin-induced maximum response by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(GUINEA PIG)
European Research Centre For Drug Discovery And Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50599902(CHEMBL5193798)
Affinity DataIC50:  3.00E+3nMAssay Description:Antagonist activity at 5-HT3 receptor in guinea-pig ileum assessed as inhibition of 5HT-induced contractionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 3A(GUINEA PIG)
European Research Centre For Drug Discovery And Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50599912(CHEMBL5209381)
Affinity DataIC50:  3.00E+3nMAssay Description:Antagonist activity at 5-HT3 receptor in guinea-pig ileum assessed as inhibition of 5HT-induced contractionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 3A(GUINEA PIG)
European Research Centre For Drug Discovery And Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50599907(CHEMBL5195091)
Affinity DataIC50: >3.00E+3nMAssay Description:Antagonist activity at 5-HT3 receptor in guinea-pig ileum assessed as inhibition of 5HT-induced contractionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 3A(GUINEA PIG)
European Research Centre For Drug Discovery And Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50599901(CHEMBL5176374)
Affinity DataIC50: >3.00E+3nMAssay Description:Antagonist activity at 5-HT3 receptor in guinea-pig ileum assessed as inhibition of 5HT-induced contractionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 3A(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50421348(CHEMBL18710)
Affinity DataIC50:  3.98E+3nMAssay Description:In Vitro Binding affinity againist 5-hydroxytryptamine 3 receptor by displacing [3H]-Q-ICS 205-930 from rat cortex homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 3A(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50421347(CHEMBL18928)
Affinity DataIC50:  4.27E+3nMAssay Description:In Vitro Binding affinity againist 5-hydroxytryptamine 3 receptor by displacing [3H]-Q-ICS 205-930 from rat cortex homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 3A(GUINEA PIG)
European Research Centre For Drug Discovery And Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50258431(CHEMBL523716 | [4-(7-Fluoropyrrolo[1,2-a]quinoxali...)
Affinity DataIC50:  5.75E+3nMAssay Description:Antagonist activity at 5HT3 receptor in spontaneously beating guinea pig right atrium assessed as inhibition of serotonin-induced maximum response by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50421346(CHEMBL19114)
Affinity DataIC50:  7.41E+3nMAssay Description:In Vitro Binding affinity againist 5-hydroxytryptamine 3 receptor by displacing [3H]-Q-ICS 205-930 from rat cortex homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 3A(GUINEA PIG)
European Research Centre For Drug Discovery And Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50258432(7-Fluoro-4-[4-(4H-[1,2,4]triazol-3-ylmethyl)-piper...)
Affinity DataIC50:  8.51E+3nMAssay Description:Antagonist activity at 5HT3 receptor in spontaneously beating guinea pig right atrium assessed as inhibition of serotonin-induced maximum response by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(GUINEA PIG)
European Research Centre For Drug Discovery And Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50599910(CHEMBL5196828)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at 5-HT3 receptor in guinea-pig ileum assessed as inhibition of 5HT-induced contractionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 3A(GUINEA PIG)
European Research Centre For Drug Discovery And Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50599917(CHEMBL5172819)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at 5-HT3 receptor in guinea-pig ileum assessed as inhibition of 5HT-induced contractionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 3A(GUINEA PIG)
European Research Centre For Drug Discovery And Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50599906(CHEMBL5173624)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at 5-HT3 receptor in guinea-pig ileum assessed as inhibition of 5HT-induced contractionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 3A(GUINEA PIG)
European Research Centre For Drug Discovery And Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50258294(2-[4-(7-Fluoropyrrolo[1,2-a]quinoxalin-4-yl)-piper...)
Affinity DataIC50:  1.12E+4nMAssay Description:Antagonist activity at 5HT3 receptor in spontaneously beating guinea pig right atrium assessed as inhibition of serotonin-induced maximum response by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(GUINEA PIG)
European Research Centre For Drug Discovery And Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50001884(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Affinity DataIC50:  1.10E+5nMAssay Description:Antagonist activity at 5-HT3 receptor in guinea-pig ileum assessed as inhibition of 5HT-induced contractionMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 3A(GUINEA PIG)
European Research Centre For Drug Discovery And Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50130293(7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...)
Affinity DataIC50:  6.30E+5nMAssay Description:Antagonist activity at 5-HT3 receptor in guinea-pig ileum assessed as inhibition of 5HT-induced contractionMore data for this Ligand-Target Pair
In DepthDetails PubMed