Compile Data Set for Download or QSAR
maximum 50k data
Found 193 of ic50 data for polymerid = 49000738
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM50558766(CHEMBL4751065)
Affinity DataIC50:  2.5nMAssay Description:Antagonist activity at human recombinant mGlu3 stably expressed in golden hamster AV12 cell membrane co-expressing Galpha15 assessed as assessed as r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM50062522((1S,2S)-2-((S)-1-amino-1-carboxy-2-(9H-xanthen-9-y...)
Affinity DataIC50:  2.80nMAssay Description:Antagonist activity at human recombinant mGlu3 stably expressed in golden hamster AV12 cell membrane co-expressing Galpha15 assessed as assessed as r...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM446832((1R,2R,3R,5R,6R)-2-amino-6-fluoro-3-[(2-oxo-1,2- d...)
Affinity DataIC50:  4.35nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM446712((1R,2R,3R,5R,6R)-2-amino-6-fluoro-3-[(1R)-1-(4- fl...)
Affinity DataIC50:  5.04nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM50558766(CHEMBL4751065)
Affinity DataIC50:  6.20nMAssay Description:Antagonist activity at human recombinant mGlu3 receptor stably expressed in golden hamster AV12 cells co-expressing rat EAAT1 assessed as reduction i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM50434133(CHEMBL2381643)
Affinity DataIC50:  6.30nMAssay Description:Agonist activity at mGlu3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM50062522((1S,2S)-2-((S)-1-amino-1-carboxy-2-(9H-xanthen-9-y...)
Affinity DataIC50:  7.70nMAssay Description:Antagonist activity at human recombinant mGlu3 receptor stably expressed in golden hamster AV12 cells co-expressing rat EAAT1 assessed as reduction i...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM50062522((1S,2S)-2-((S)-1-amino-1-carboxy-2-(9H-xanthen-9-y...)
Affinity DataIC50:  10nMAssay Description:Effect on 1S,3R-ACPD-induced inhibition of forskolin stimulated cyclic-AMP in RGT cells expressing human Metabotropic glutamate receptor 3More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM50434132(CHEMBL2381642)
Affinity DataIC50:  11nMAssay Description:Agonist activity at mGlu3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM50558769(CHEMBL4746125)
Affinity DataIC50:  12nMAssay Description:Antagonist activity at human recombinant mGlu3 receptor stably expressed in golden hamster AV12 cells co-expressing rat EAAT1 assessed as reduction i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM446818((1R,2R,3R,5R,6R)-2-amino-3-[(5-chloropyridin-2- yl...)
Affinity DataIC50:  12.4nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM50062522((1S,2S)-2-((S)-1-amino-1-carboxy-2-(9H-xanthen-9-y...)
Affinity DataIC50:  14nMAssay Description:Antagonist activity at human mGLUR3 expressed in RGT cells assessed as inhibition of (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid-induced inhibi...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM50204259(CHEMBL3913414)
Affinity DataIC50:  14nMAssay Description:Antagonist activity at recombinant human mGlu3 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM446701(US10689327, Compound (II)-2)
Affinity DataIC50:  14.8nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM446836((1S,2R,3R,5R,6S)-2-amino-3-[(3,4- difluorophenyl)m...)
Affinity DataIC50:  15.2nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM50279772(2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)-ethyl]-cy...)
Affinity DataIC50:  16nMAssay Description:Ability to block 1S,3R-ACPD-induced inhibition of forskolin stimulated cyclic-AMP in non-neuronal cell line expressing human Metabotropic glutamate r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM50558768(CHEMBL4759992)
Affinity DataIC50:  16nMAssay Description:Antagonist activity at human recombinant mGlu3 receptor stably expressed in golden hamster AV12 cells co-expressing rat EAAT1 assessed as reduction i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM50204267(CHEMBL3939492)
Affinity DataIC50:  21nMAssay Description:Antagonist activity at recombinant human mGlu3 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM50151435((1R,2R,3R,5R,6R)-2-Amino-3-(3,4-dichloro-benzyloxy...)
Affinity DataIC50:  24nMAssay Description:Antagonist activity at mGLUR3 expressed in CHO cells assessed as inhibition of glutamate-induced inhibition of forskolin-stimulated cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM50204261(CHEMBL3969063)
Affinity DataIC50:  24nMAssay Description:Antagonist activity at recombinant human mGlu3 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM50558774(CHEMBL4780402)
Affinity DataIC50:  27nMAssay Description:Antagonist activity at human recombinant mGlu3 receptor stably expressed in golden hamster AV12 cells co-expressing rat EAAT1 assessed as reduction i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM50056272((1S,2S,5R,6S)-2-Amino-bicyclo[3.1.0]hexane-2,6-dic...)
Affinity DataIC50:  28nMAssay Description:Agonist activity at mGlu3 (unknown origin)More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM50204256(CHEMBL3948272)
Affinity DataIC50:  30nMAssay Description:Antagonist activity at recombinant human mGlu3 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM446784((1R,2R,3R,5R,6R)-2-amino-3-[(6-chloropyridin-2- yl...)
Affinity DataIC50:  32.3nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM446699(US10689327, Compound (II)-1)
Affinity DataIC50:  36.4nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM50204268(CHEMBL3977508)
Affinity DataIC50:  39nMAssay Description:Antagonist activity at recombinant human mGlu3 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM50558775(CHEMBL4776989)
Affinity DataIC50:  42nMAssay Description:Antagonist activity at human recombinant mGlu3 receptor stably expressed in golden hamster AV12 cells co-expressing rat EAAT1 assessed as reduction i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM50204257(CHEMBL3947221)
Affinity DataIC50:  46nMAssay Description:Antagonist activity at recombinant human mGlu3 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM446817((1R,2R,3R,5R,6R)-2-amino-3-[(6-chloropyridin-3- yl...)
Affinity DataIC50:  50.6nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM50204258(CHEMBL3933829)
Affinity DataIC50:  54nMAssay Description:Antagonist activity at recombinant human mGlu3 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM446828((1R,2R,3R,5R,6R)-2-amino-6-fluoro-3-[(4- methylphe...)
Affinity DataIC50:  54.4nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM50558772(CHEMBL4748699)
Affinity DataIC50:  57nMAssay Description:Antagonist activity at human recombinant mGlu3 receptor stably expressed in golden hamster AV12 cells co-expressing rat EAAT1 assessed as reduction i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM446857(US10689327, Compound (II)-15)
Affinity DataIC50:  60.5nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM50558773(CHEMBL4757159)
Affinity DataIC50:  61nMAssay Description:Antagonist activity at human recombinant mGlu3 receptor stably expressed in golden hamster AV12 cells co-expressing rat EAAT1 assessed as reduction i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM50558771(CHEMBL4760856)
Affinity DataIC50:  62nMAssay Description:Antagonist activity at human recombinant mGlu3 receptor stably expressed in golden hamster AV12 cells co-expressing rat EAAT1 assessed as reduction i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM50204266(CHEMBL3961306)
Affinity DataIC50:  71nMAssay Description:Antagonist activity at recombinant human mGlu3 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM446739((1R,2R,3R,5R,6R)-2-amino-6-fluoro-3-[(3- fluorophe...)
Affinity DataIC50:  75.5nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM50204253(CHEMBL3956934)
Affinity DataIC50:  76nMAssay Description:Antagonist activity at recombinant human mGlu3 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM50408697(CHEMBL2112634)
Affinity DataIC50:  80nMAssay Description:Effect on 1S,3R-ACPD-induced inhibition of forskolin stimulated cyclic-AMP in RGT cells expressing human Metabotropic glutamate receptor 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM50062520((1S,2S)-2-((R)-1-Amino-1-carboxy-3-m-tolyl-propyl)...)
Affinity DataIC50:  80nMAssay Description:Effect on 1S,3R-ACPD-induced inhibition of forskolin stimulated cyclic-AMP in RGT cells expressing human Metabotropic glutamate receptor 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM50204270(CHEMBL3918170)
Affinity DataIC50:  83nMAssay Description:Antagonist activity at recombinant human mGlu3 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM50204255(CHEMBL3927108)
Affinity DataIC50:  85nMAssay Description:Antagonist activity at recombinant human mGlu3 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM50121652(CHEMBL3616851)
Affinity DataIC50:  95nMAssay Description:Antagonist activity at human recombinant mGlu3 receptor expressed in AV12 cells assessed as inhibition of glutamate-stimulated Ca2+ mobilization afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM50151462((1R,2R,3R,5R,6R)-2-Amino-3-cyclopentyloxy-6-fluoro...)
Affinity DataIC50:  97.6nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM50204253(CHEMBL3956934)
Affinity DataIC50:  110nMAssay Description:Antagonist activity at human recombinant mGlu3 receptor stably expressed in golden hamster AV12 cells co-expressing rat EAAT1 assessed as reduction i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM50204264(CHEMBL3890112)
Affinity DataIC50:  127nMAssay Description:Antagonist activity at recombinant human mGlu3 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM50204260(CHEMBL3971347)
Affinity DataIC50:  145nMAssay Description:Antagonist activity at recombinant human mGlu3 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM50204269(CHEMBL3909237)
Affinity DataIC50:  153nMAssay Description:Antagonist activity at recombinant human mGlu3 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM50121651(CHEMBL3616850)
Affinity DataIC50:  154nMAssay Description:Antagonist activity at human recombinant mGlu3 receptor expressed in AV12 cells assessed as inhibition of glutamate-stimulated Ca2+ mobilization afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM50062534((S)-2-[(R)-1-Amino-1-carboxy-3-(3-methoxy-phenyl)-...)
Affinity DataIC50:  160nMAssay Description:Effect on 1S,3R-ACPD-induced inhibition of forskolin stimulated cyclic-AMP in RGT cells expressing human Metabotropic glutamate receptor 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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