Compile Data Set for Download or QSAR
maximum 50k data
Found 12 of ic50 data for polymerid = 50002102
TargetProbable C-C chemokine receptor type 3(Mus musculus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209974(1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-y...)
Affinity DataIC50:  3.60nMAssay Description:Displacement of [125I]eotaxin from BALB/c mouse CCR3 expressed in CHO cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable C-C chemokine receptor type 3(Mus musculus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209974(1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-y...)
Affinity DataIC50:  7nMAssay Description:Antagonist activity at CCR3 assessed as eotaxin-induced chemotaxis in BALB/c mouse eosinophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable C-C chemokine receptor type 3(Mus musculus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50163636(1-((1R,2S)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-y...)
Affinity DataIC50:  10nMAssay Description:Inhibition of eotaxin-induced chemotaxis of mouse eosinophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable C-C chemokine receptor type 3(Mus musculus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50163634(1-((1R,2S)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-y...)
Affinity DataIC50:  20nMAssay Description:Inhibition of eotaxin-induced chemotaxis of mouse eosinophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable C-C chemokine receptor type 3(Mus musculus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50231358(1-((2R,3S)-4-((S)-3-(4-fluorobenzyl)piperidin-1-yl...)
Affinity DataIC50:  31nMAssay Description:Antagonist activity at CCR3 receptor in mouse eosinophil assessed as as inhibition of chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable C-C chemokine receptor type 3(Mus musculus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209971(1-((1R,2S)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-y...)
Affinity DataIC50:  41nMAssay Description:Inhibition of eotaxin-induced chemotaxis of mouse eosinophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable C-C chemokine receptor type 3(Mus musculus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209971(1-((1R,2S)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-y...)
Affinity DataIC50:  41nMAssay Description:Antagonist activity at CCR3 assessed as eotaxin-induced chemotaxis in BALB/c mouse eosinophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable C-C chemokine receptor type 3(Mus musculus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209971(1-((1R,2S)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-y...)
Affinity DataIC50:  54nMAssay Description:Displacement of [125I]eotaxin from BALB/c mouse CCR3 expressed in CHO cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable C-C chemokine receptor type 3(Mus musculus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50297171(CHEMBL551735 | N-{(3R)-1-[(6-Fluoro-2-naphthyl)met...)
Affinity DataIC50:  230nMAssay Description:Inhibition of mouse CCR3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable C-C chemokine receptor type 3(Mus musculus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50098624(1-Cyclooct-1-enylmethyl-4-[(2,7-dichloro-9H-xanthe...)
Affinity DataIC50:  350nMAssay Description:Inhibitory activity against I-Eotaxin induced [Ca2+] response in mouse CCR3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable C-C chemokine receptor type 3(Mus musculus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50098624(1-Cyclooct-1-enylmethyl-4-[(2,7-dichloro-9H-xanthe...)
Affinity DataIC50:  460nMAssay Description:Inhibitory activity against I-Eotaxin alpha binding to mouse CCR3 receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable C-C chemokine receptor type 3(Mus musculus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50264212(CHEMBL519042 | N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of mouse CCR3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed