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Found 26 of ic50 data for polymerid = 50006394
TargetUbiquitin carboxyl-terminal hydrolase 2(Homo sapiens (Human))
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50458422(CHEMBL4216958)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of human USP2a (258 to 605 residues) expressed in Escherichia coli BL21(DE3) using Ub-AMC as substrate incubated for 30 mins measured at 3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Homo sapiens (Human))
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50591324(CHEMBL5185273)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of USP2 (unknown origin) using Ub-Rho measured after 0.5 to 3 hrsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Homo sapiens (Human))
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50591321(CHEMBL5172138)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of USP2 (unknown origin) using Ub-Rho measured after 0.5 to 3 hrsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Homo sapiens (Human))
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50591322(CHEMBL5196686)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of USP2 (unknown origin) using Ub-Rho measured after 0.5 to 3 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Homo sapiens (Human))
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50458415(CHEMBL567508 | EN300-02284)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of human USP2a (258 to 605 residues) expressed in Escherichia coli BL21(DE3) using Ub-AMC as substrate incubated for 30 mins measured at 3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Homo sapiens (Human))
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50514116(CHEMBL4458718)
Affinity DataIC50:  9.70E+3nMAssay Description:Inhibition of USP2 (unknown origin) using Ub-AMC substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Homo sapiens (Human))
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50591323(CHEMBL5173239)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of USP2 (unknown origin) using Ub-Rho measured after 0.5 to 3 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Homo sapiens (Human))
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50538571(CHEMBL4635160)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human GST-tagged USP2 isoform 4 expressed in Escherichia coli assessed as cleavage of Ubiquitin-Rhodamine110-glycine to Ubiquitin and R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Homo sapiens (Human))
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50442907(Acetyl Isogambogic Acid | CHEMBL3039433)
Affinity DataIC50:  1.82E+4nMpH: 7.5 T: 2°CAssay Description:Ubiquitin-7-amino-4-methylcoumarin (Ub-AMC) was generated as previously described.(7) The enzymatic reaction was conducted in fluorometric assay buff...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Homo sapiens (Human))
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM200235(Rifampicin | cid_5381226)
Affinity DataIC50:  2.12E+4nMpH: 7.5 T: 2°CAssay Description:Ubiquitin-7-amino-4-methylcoumarin (Ub-AMC) was generated as previously described.(7) The enzymatic reaction was conducted in fluorometric assay buff...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Homo sapiens (Human))
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM217379(CDDO-Me, 2)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of USP2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Homo sapiens (Human))
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM205457((2R,4aS,6aR,6aS,14aS,14bR)-10-hydroxy-2,4a,6a,6a,9...)
Affinity DataIC50:  2.87E+4nMpH: 7.5 T: 2°CAssay Description:Ubiquitin-7-amino-4-methylcoumarin (Ub-AMC) was generated as previously described.(7) The enzymatic reaction was conducted in fluorometric assay buff...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Homo sapiens (Human))
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50436152(SPONGIACIDIN C)
Affinity DataIC50: >3.16E+4nMAssay Description:Inhibition of core catalytic domain of USP2 (unknown origin) using diubiquitin IQF K4804 as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Homo sapiens (Human))
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50072959(CHEMBL3410535)
Affinity DataIC50:  3.26E+4nMAssay Description:Inhibition of USP2 catalytic domain (unknown origin) expressed in bacteria using Ub-AMC as substrate preincubated for 30 mins before substrate additi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Homo sapiens (Human))
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50458419(CHEMBL4203286)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human USP2a (258 to 605 residues) expressed in Escherichia coli BL21(DE3) using Ub-AMC as substrate incubated for 30 mins measured at 3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Homo sapiens (Human))
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50597468(CHEMBL5184337)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of USP2 (267 to 599 residues) (unknown origin) catalytic domain expressed in Escherichia coli BL21 (DE3) cells using ubiquitin-rhodamine -...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Homo sapiens (Human))
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50269827(CHEMBL4089822)
Affinity DataIC50:  6.61E+4nMAssay Description:Inhibition of recombinant human N-terminal His-tagged USP2 catalytic domain (258 to 605 residues) expressed in Escherichia coli BL21(DE3) using human...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Homo sapiens (Human))
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50242207(CHEMBL455364 | Mangiferin)
Affinity DataIC50:  6.78E+4nMpH: 7.5 T: 2°CAssay Description:Ubiquitin-7-amino-4-methylcoumarin (Ub-AMC) was generated as previously described.(7) The enzymatic reaction was conducted in fluorometric assay buff...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Homo sapiens (Human))
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50458417(CHEMBL4203489)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human USP2a (258 to 605 residues) expressed in Escherichia coli BL21(DE3) using Ub-AMC as substrate incubated for 30 mins measured at 3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Homo sapiens (Human))
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50007788(CHEMBL3233809 | med.21724, Compound 167)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human USP2 using Ub-rhodamine 110 as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Homo sapiens (Human))
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50069762(CHEMBL3182437 | ML323 | US9802904, 87)
Affinity DataIC50: >1.14E+5nMpH: 7.5 T: 2°CAssay Description:Ubiquitin-7-amino-4-methylcoumarin (Ub-AMC) was generated as previously described.(7) The enzymatic reaction was conducted in fluorometric assay buff...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Homo sapiens (Human))
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM65524((-)-Aricine | Heterophylline (VAN) | Quinovatine)
Affinity DataIC50: >1.14E+5nMpH: 7.5 T: 2°CAssay Description:Ubiquitin-7-amino-4-methylcoumarin (Ub-AMC) was generated as previously described.(7) The enzymatic reaction was conducted in fluorometric assay buff...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Homo sapiens (Human))
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50458416(CHEMBL1230155)
Affinity DataIC50:  1.30E+6nMAssay Description:Inhibition of human USP2a (258 to 605 residues) expressed in Escherichia coli BL21(DE3) using Ub-AMC as substrate incubated for 30 mins measured at 3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Homo sapiens (Human))
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50458420(CHEMBL4207620)
Affinity DataIC50: >5.00E+6nMAssay Description:Inhibition of human USP2a (258 to 605 residues) expressed in Escherichia coli BL21(DE3) using Ub-AMC as substrate incubated for 30 mins measured at 3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Homo sapiens (Human))
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50458418(CHEMBL4207578)
Affinity DataIC50: >5.00E+6nMAssay Description:Inhibition of human USP2a (258 to 605 residues) expressed in Escherichia coli BL21(DE3) using Ub-AMC as substrate incubated for 30 mins measured at 3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Homo sapiens (Human))
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50458421(CHEMBL1650269)
Affinity DataIC50: >5.00E+6nMAssay Description:Inhibition of human USP2a (258 to 605 residues) expressed in Escherichia coli BL21(DE3) using Ub-AMC as substrate incubated for 30 mins measured at 3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed