Compile Data Set for Download or QSAR
maximum 50k data
Found 358 of ic50 data for polymerid = 759
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Irm

US Patent
LigandPNGBDBM103511(US8546370, 17)
Affinity DataIC50:  1nMAssay Description:Homogenous time-resolved fluorescence assay using Syk enzyme.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Irm

US Patent
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of N-terminal GST-fused human recombinant full length ZAP70 (1 to 619 residues) expressed in baculovirus-infected Sf21 cells using FAM-22 ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Irm

US Patent
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of ZAP70 (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Irm

US Patent
LigandPNGBDBM103519(US8546370, 164)
Affinity DataIC50:  2nMAssay Description:Homogenous time-resolved fluorescence assay using Syk enzyme.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Irm

US Patent
LigandPNGBDBM103512(US8546370, 83)
Affinity DataIC50:  3nMAssay Description:Homogenous time-resolved fluorescence assay using Syk enzyme.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Irm

US Patent
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of human ZAP70 using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Irm

US Patent
LigandPNGBDBM50075735(CHEMBL3415583)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of GST-fused Zap70 (unknown origin) expressed in insect SF9 cells using biotin-EQEDEPEGDYFEWLE-CONH2 as substrate preincubated for 10 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Irm

US Patent
LigandPNGBDBM50075735(CHEMBL3415583)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of LCK activated GST-fused ZAP70 (unknown origin) expressed in fall armyworm sf9 cells preincubated for 10 mins followed by biotin-EQEDEPE...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Irm

US Patent
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  7.40nMAssay Description:Inhibition of human ZAP70 using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Irm

US Patent
LigandPNGBDBM50083639(CHEMBL112346 | {4-[6-((S)-3-Ethyl-piperazin-1-yl)-...)
Affinity DataIC50:  8nMAssay Description:Inhibition of Zeta-chain (TCR) associated protein kinase 70 kDa phosphorylation of polyGly-Tyr.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Irm

US Patent
LigandPNGBDBM103522(US8546370, 190)
Affinity DataIC50:  8nMAssay Description:Homogenous time-resolved fluorescence assay using Syk enzyme.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Irm

US Patent
LigandPNGBDBM103524(US8546370, 304)
Affinity DataIC50:  8nMAssay Description:Homogenous time-resolved fluorescence assay using Syk enzyme.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Irm

US Patent
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  8.60nMAssay Description:Inhibition of ZAP70 using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence microplate...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Irm

US Patent
LigandPNGBDBM103512(US8546370, 83)
Affinity DataIC50:  9nMAssay Description:Homogenous time-resolved fluorescence assay using Syk enzyme.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Irm

US Patent
LigandPNGBDBM50300382(4-(4-(5-chloro-4-(2-(propylsulfonyl)phenylamino)py...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human GST-fused ZAP-70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Irm

US Patent
LigandPNGBDBM50442759(CHEMBL2443138)
Affinity DataIC50: >10nMAssay Description:Inhibition of ZAP70 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Irm

US Patent
LigandPNGBDBM50300401(2-(5-bromo-2-(2,3-dihydro-1H-inden-4-ylamino)pyrim...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human GST-fused ZAP-70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Irm

US Patent
LigandPNGBDBM50442757(CHEMBL2443026)
Affinity DataIC50: >10nMAssay Description:Inhibition of ZAP70 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Irm

US Patent
LigandPNGBDBM50442758(CHEMBL2443139)
Affinity DataIC50: >10nMAssay Description:Inhibition of ZAP70 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Irm

US Patent
LigandPNGBDBM50442760(CHEMBL2443044)
Affinity DataIC50: >10nMAssay Description:Inhibition of ZAP70 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Irm

US Patent
LigandPNGBDBM50083638((S)-4-(6-(3-methylpiperazin-1-yl)pyridin-3-yl)-N-(...)
Affinity DataIC50:  11nMAssay Description:Inhibition of Zeta-chain (TCR) associated protein kinase 70 kDa phosphorylation of polyGly-Tyr.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Irm

US Patent
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  12.4nMAssay Description:Inhibition of human ZAP70 using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Irm

US Patent
LigandPNGBDBM50013165(CHEMBL3262616)
Affinity DataIC50:  14nMAssay Description:Inhibition of ZAP70 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Irm

US Patent
LigandPNGBDBM50013170(CHEMBL3262622)
Affinity DataIC50:  18nMAssay Description:Inhibition of ZAP70 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Irm

US Patent
LigandPNGBDBM103521(US8546370, 183)
Affinity DataIC50:  24nMAssay Description:Homogenous time-resolved fluorescence assay using Syk enzyme.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Irm

US Patent
LigandPNGBDBM50083649(CHEMBL112518 | {4-[6-(3-Methyl-piperazin-1-yl)-pyr...)
Affinity DataIC50:  26nMAssay Description:Inhibition of Zeta-chain (TCR) associated protein kinase 70 kDa phosphorylation of polyGly-Tyr.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Irm

US Patent
LigandPNGBDBM50069336(CHEMBL439120 | NELNLGRREE | NQLPpYNELNLGRREEpYDVLD)
Affinity DataIC50:  30nMAssay Description:Antagonistic activity against SH2 domain of Zeta-chain (TCR) associated protein kinase, ZAP-70More data for this Ligand-Target Pair
In DepthDetails Article
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Irm

US Patent
LigandPNGBDBM50069336(CHEMBL439120 | NELNLGRREE | NQLPpYNELNLGRREEpYDVLD)
Affinity DataIC50:  30nMAssay Description:Inhibition of binding to human ZAP-70 SH2 domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Irm

US Patent
LigandPNGBDBM50083640(CHEMBL112172 | [4-(6-[1,4]Diazepan-1-yl-pyridin-3-...)
Affinity DataIC50:  31nMAssay Description:Inhibition of Zeta-chain (TCR) associated protein kinase 70 kDa phosphorylation of polyGly-Tyr.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Irm

US Patent
LigandPNGBDBM103530(US8546370, 643)
Affinity DataIC50:  31nMAssay Description:Homogenous time-resolved fluorescence assay using Syk enzyme.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Irm

US Patent
LigandPNGBDBM50013162(CHEMBL3262357)
Affinity DataIC50:  33nMAssay Description:Inhibition of ZAP70 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Irm

US Patent
LigandPNGBDBM50300383(4-(4-(5-chloro-4-(2-(propylsulfonyl)phenylamino)py...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human GST-fused ZAP-70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Irm

US Patent
LigandPNGBDBM50274757(5-((1S,2R)-2-Aminocyclohexylamino)-7-(3,5-dimethox...)
Affinity DataIC50:  41nMAssay Description:Inhibition of human ZAP70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Irm

US Patent
LigandPNGBDBM60665(BDBM50249542 | US9145414, R406 | US9212178, R406)
Affinity DataIC50:  42nMAssay Description:Inhibition of ZAP70 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Irm

US Patent
LigandPNGBDBM103517(US8546370, 130)
Affinity DataIC50:  44nMAssay Description:Homogenous time-resolved fluorescence assay using Syk enzyme.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Irm

US Patent
LigandPNGBDBM50083648(CHEMBL420672 | {4-[6-(4-Methyl-piperazin-1-yl)-pyr...)
Affinity DataIC50:  46nMAssay Description:Inhibition of Zeta-chain (TCR) associated protein kinase 70 kDa phosphorylation of polyGly-Tyr.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Irm

US Patent
LigandPNGBDBM103529(US8546370, 637)
Affinity DataIC50:  46nMAssay Description:Homogenous time-resolved fluorescence assay using Syk enzyme.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Irm

US Patent
LigandPNGBDBM50013169(CHEMBL3262620)
Affinity DataIC50:  47nMAssay Description:Inhibition of ZAP70 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Irm

US Patent
LigandPNGBDBM26429((2E)-3-{4-[({8-carbamoyl-7-[(3,5-dimethoxyphenyl)a...)
Affinity DataIC50:  47nMpH: 7.6 T: 2°CAssay Description:A coupled spectrophotometric assay was used wherein ADP generated by ZAP-70 kinase was converted to ATP by pyruvate kinase (PK), with concomitant pro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Irm

US Patent
LigandPNGBDBM103532(US8546370, 1124)
Affinity DataIC50:  48nMAssay Description:Homogenous time-resolved fluorescence assay using Syk enzyme.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Irm

US Patent
LigandPNGBDBM50300384(2-(5-chloro-2-(4-(3-(dimethylamino)-2,2-dimethylpr...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human GST-fused ZAP-70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Irm

US Patent
LigandPNGBDBM50059889((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...)
Affinity DataIC50:  53nMAssay Description:Inhibition of human ZAP70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Irm

US Patent
LigandPNGBDBM50059889((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...)
Affinity DataIC50:  53nMAssay Description:Inhibition of human ZAP70More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Irm

US Patent
LigandPNGBDBM50083644(CHEMBL322066 | [4-(6-Piperazin-1-yl-pyridin-3-yl)-...)
Affinity DataIC50:  54nMAssay Description:Inhibition of Zeta-chain (TCR) associated protein kinase 70 kDa phosphorylation of polyGly-Tyr.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Irm

US Patent
LigandPNGBDBM50570681(CHEMBL4870513)
Affinity DataIC50:  55nMAssay Description:Inhibition of N-terminal GST-fused human recombinant full length ZAP70 (1 to 619 residues) expressed in baculovirus-infected Sf21 cells using FAM-22 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Irm

US Patent
LigandPNGBDBM103510(US8546370, 11)
Affinity DataIC50:  58nMAssay Description:Homogenous time-resolved fluorescence assay using Syk enzyme.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Irm

US Patent
LigandPNGBDBM50400047(BIIB-057 | CHEMBL2177736 | US9579320, Example 87)
Affinity DataIC50:  60nMAssay Description:Inhibition of ZAP70 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Irm

US Patent
LigandPNGBDBM50400047(BIIB-057 | CHEMBL2177736 | US9579320, Example 87)
Affinity DataIC50:  68nMAssay Description:Inhibition of human ZAP70More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Irm

US Patent
LigandPNGBDBM50300385(2-(5-bromo-2-(3-(dimethylamino)-2-methylphenylamin...)
Affinity DataIC50:  70nMAssay Description:Inhibition of human GST-fused ZAP-70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Irm

US Patent
LigandPNGBDBM50013160(CHEMBL3262355)
Affinity DataIC50:  74nMAssay Description:Inhibition of ZAP70 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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