TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataKd: 0.00500nMAssay Description:Displacement of ARC-1063 fluorescent probe from recombinant human PKAC-alpha assessed as dissociation equilibrium constant preincubated for 1 hr foll...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit beta(Homo sapiens (Human))
Cha University
Curated by ChEMBL
Cha University
Curated by ChEMBL
Affinity DataKd: 0.0130nMAssay Description:Binding affinity to human wild-type PKAc beta assessed as dissociation constantMore data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataKd: 0.0190nMAssay Description:Displacement of ARC-1063 fluorescent probe from recombinant human PKAC-alpha assessed as dissociation equilibrium constant preincubated for 1 hr foll...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataKd: 0.0420nMAssay Description:Displacement of mAb(D38C6)-BTN from human recombinant PKAc alpha incubated for 15 mins by microplate reader assayMore data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Mus musculus (mouse))
University Of Tartu
University Of Tartu
Affinity DataKd: 0.5nMpH: 7.5 T: 2°CAssay Description:The assay is based on the kinase-bound labeled fluorescent probe can be displaced by competitive inhibitors, which can be registered by measurement o...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Mus musculus (mouse))
University Of Tartu
University Of Tartu
Affinity DataKd: <0.5nMpH: 7.5 T: 2°CAssay Description:The assay is based on the kinase-bound labeled fluorescent probe can be displaced by competitive inhibitors, which can be registered by measurement o...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataKd: 0.630nMAssay Description:Displacement of ARC-1063 fluorescent probe from recombinant human PKAC-alpha assessed as dissociation equilibrium constant preincubated for 1 hr foll...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Mus musculus (mouse))
University Of Tartu
University Of Tartu
Affinity DataKd: 1.80nMpH: 7.5 T: 2°CAssay Description:The assay is based on the kinase-bound labeled fluorescent probe can be displaced by competitive inhibitors, which can be registered by measurement o...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataKd: 3.90nMAssay Description:Binding affinity to PKAalpha (unknown origin) using Lys-Arg-Thr-Leu-Arg-Arg as substrate after 8 mins in presence of [gamma-32P]ATP by liquid scintil...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataKd: 4.10nMpH: 7.5Assay Description:All measurements were performed in HEPES (50 mm, pH 7.5) containing NaCl (150 mm), Tween-20 (0.005%) and DTT (5 mm) according to a previously publish...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataKd: 4.20nMAssay Description:Displacement of ARC-1063 fluorescent probe from recombinant human PKAC-alpha assessed as dissociation equilibrium constant preincubated for 1 hr foll...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Mus musculus (mouse))
University Of Tartu
University Of Tartu
Affinity DataKd: 5.80nMpH: 7.5 T: 2°CAssay Description:The assay is based on the kinase-bound labeled fluorescent probe can be displaced by competitive inhibitors, which can be registered by measurement o...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Mus musculus (mouse))
University Of Tartu
University Of Tartu
Affinity DataKd: 7.60nMpH: 7.5 T: 2°CAssay Description:The assay is based on the kinase-bound labeled fluorescent probe can be displaced by competitive inhibitors, which can be registered by measurement o...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Mus musculus (mouse))
University Of Tartu
University Of Tartu
Affinity DataKd: 8.70nMpH: 7.5 T: 2°CAssay Description:The assay is based on the kinase-bound labeled fluorescent probe can be displaced by competitive inhibitors, which can be registered by measurement o...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Mus musculus (mouse))
University Of Tartu
University Of Tartu
Affinity DataKd: 9.5nMpH: 7.5 T: 2°CAssay Description:The assay is based on the kinase-bound labeled fluorescent probe can be displaced by competitive inhibitors, which can be registered by measurement o...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataKd: 9.60nMpH: 7.5Assay Description:All measurements were performed in HEPES (50 mm, pH 7.5) containing NaCl (150 mm), Tween-20 (0.005%) and DTT (5 mm) according to a previously publish...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Mus musculus (mouse))
University Of Tartu
University Of Tartu
Affinity DataKd: 12.6nMpH: 7.5 T: 2°CAssay Description:The assay is based on the kinase-bound labeled fluorescent probe can be displaced by competitive inhibitors, which can be registered by measurement o...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit beta(Homo sapiens (Human))
Cha University
Curated by ChEMBL
Cha University
Curated by ChEMBL
Affinity DataKd: 13nMAssay Description:Binding constant for PKAC-beta kinase domainMore data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataKd: 19nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataKd: 19nMAssay Description:Binding constant for PKAC-alpha kinase domainMore data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataKd: 19nMAssay Description:Binding constant for PKAC-alpha kinase domainMore data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataKd: 19nMAssay Description:Binding constant for PKAC-alpha kinase domainMore data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Mus musculus (mouse))
University Of Tartu
University Of Tartu
Affinity DataKd: 23nMpH: 7.5 T: 2°CAssay Description:The assay is based on the kinase-bound labeled fluorescent probe can be displaced by competitive inhibitors, which can be registered by measurement o...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit beta(Homo sapiens (Human))
Cha University
Curated by ChEMBL
Cha University
Curated by ChEMBL
Affinity DataKd: 29nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit beta(Homo sapiens (Human))
Cha University
Curated by ChEMBL
Cha University
Curated by ChEMBL
Affinity DataKd: 29nMAssay Description:Binding constant for PKAC-beta kinase domainMore data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit beta(Homo sapiens (Human))
Cha University
Curated by ChEMBL
Cha University
Curated by ChEMBL
Affinity DataKd: 29nMAssay Description:Binding constant for full-length PKAC-betaMore data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataKd: 42nMAssay Description:Binding affinity to recombinant human full length N-terminal GST-tagged PRKACA expressed in baculovirus expression system using kemptide as substrate...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataKd: 52nMpH: 7.5Assay Description:All measurements were performed in HEPES (50 mm, pH 7.5) containing NaCl (150 mm), Tween-20 (0.005%) and DTT (5 mm) according to a previously publish...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataKd: 56nMAssay Description:Binding constant for PKAC-alpha kinase domainMore data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit beta(Homo sapiens (Human))
Cha University
Curated by ChEMBL
Cha University
Curated by ChEMBL
Affinity DataKd: 64nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged PRKACB (unknown origin) expressed in baculovirus infected Sf9 insect cells...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit beta(Homo sapiens (Human))
Cha University
Curated by ChEMBL
Cha University
Curated by ChEMBL
Affinity DataKd: 66nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged PRKACB (unknown origin) expressed in baculovirus infected Sf9 insect cells...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Mus musculus (mouse))
University Of Tartu
University Of Tartu
Affinity DataKd: 83nMpH: 7.5 T: 2°CAssay Description:The assay is based on the kinase-bound labeled fluorescent probe can be displaced by competitive inhibitors, which can be registered by measurement o...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit beta(Homo sapiens (Human))
Cha University
Curated by ChEMBL
Cha University
Curated by ChEMBL
Affinity DataKd: 90nMAssay Description:Binding constant for PKAC-beta kinase domainMore data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataKd: 94nMpH: 7.5Assay Description:All measurements were performed in HEPES (50 mm, pH 7.5) containing NaCl (150 mm), Tween-20 (0.005%) and DTT (5 mm) according to a previously publish...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Mus musculus (mouse))
University Of Tartu
University Of Tartu
Affinity DataKd: 95.4nMpH: 7.5 T: 2°CAssay Description:The assay is based on the kinase-bound labeled fluorescent probe can be displaced by competitive inhibitors, which can be registered by measurement o...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataKd: 116nMAssay Description:Binding affinity to recombinant human full length N-terminal GST-tagged PRKACA expressed in baculovirus expression system using kemptide as substrate...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit beta(Homo sapiens (Human))
Cha University
Curated by ChEMBL
Cha University
Curated by ChEMBL
Affinity DataKd: 160nMAssay Description:Binding constant for PKAC-beta kinase domainMore data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit beta(Homo sapiens (Human))
Cha University
Curated by ChEMBL
Cha University
Curated by ChEMBL
Affinity DataKd: 160nMAssay Description:Binding affinity to PKAC-betaMore data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataKd: 220nMAssay Description:Binding constant for PKAC-alpha kinase domainMore data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit beta(Homo sapiens (Human))
Cha University
Curated by ChEMBL
Cha University
Curated by ChEMBL
Affinity DataKd: 240nMAssay Description:Binding constant for full-length PKAC-betaMore data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit beta(Homo sapiens (Human))
Cha University
Curated by ChEMBL
Cha University
Curated by ChEMBL
Affinity DataKd: 240nMAssay Description:Binding constant for PKAC-beta kinase domainMore data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit beta(Homo sapiens (Human))
Cha University
Curated by ChEMBL
Cha University
Curated by ChEMBL
Affinity DataKd: 240nMAssay Description:Binding affinity to PKAC-betaMore data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit beta(Homo sapiens (Human))
Cha University
Curated by ChEMBL
Cha University
Curated by ChEMBL
Affinity DataKd: 240nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Mus musculus (mouse))
University Of Tartu
University Of Tartu
Affinity DataKd: 247nMpH: 7.5 T: 2°CAssay Description:The assay is based on the kinase-bound labeled fluorescent probe can be displaced by competitive inhibitors, which can be registered by measurement o...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Mus musculus (mouse))
University Of Tartu
University Of Tartu
Affinity DataKd: 249nMpH: 7.5 T: 2°CAssay Description:The assay is based on the kinase-bound labeled fluorescent probe can be displaced by competitive inhibitors, which can be registered by measurement o...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit beta(Homo sapiens (Human))
Cha University
Curated by ChEMBL
Cha University
Curated by ChEMBL
Affinity DataKd: 260nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit beta(Homo sapiens (Human))
Cha University
Curated by ChEMBL
Cha University
Curated by ChEMBL
Affinity DataKd: 260nMAssay Description:Binding constant for PKAC-beta kinase domainMore data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit beta(Homo sapiens (Human))
Cha University
Curated by ChEMBL
Cha University
Curated by ChEMBL
Affinity DataKd: 260nMAssay Description:Binding constant for full-length PKAC-betaMore data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Mus musculus (mouse))
University Of Tartu
University Of Tartu
Affinity DataKd: 319nMpH: 7.5 T: 2°CAssay Description:The assay is based on the kinase-bound labeled fluorescent probe can be displaced by competitive inhibitors, which can be registered by measurement o...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataKd: 330nMAssay Description:Binding constant for PKAC-alpha kinase domainMore data for this Ligand-Target Pair