Compile Data Set for Download or QSAR
maximum 50k data
Found 239 of kd data for polymerid = 50007196,50006553
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50539553(CHEMBL4644995)
Affinity DataKd:  0.0700nMAssay Description:Binding affinity to Keap1 (unknown origin) by SPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50539550(CHEMBL4643134)
Affinity DataKd:  0.700nMAssay Description:Binding affinity to Keap1 kelch domain (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50539550(CHEMBL4643134)
Affinity DataKd:  0.700nMAssay Description:Binding affinity to Keap1 (unknown origin) by SPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50539551(CHEMBL4633657)
Affinity DataKd:  0.880nMAssay Description:Binding affinity to Keap1 (unknown origin) by SPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50180850(CHEMBL3819587)
Affinity DataKd:  1.30nMAssay Description:Binding affinity to human recombinant N-terminal His6 and Avi-tagged KEAP1 (321 to 609 residues) expressed in baculovirus infected sf9 cells by isoth...More data for this Ligand-Target Pair
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50180850(CHEMBL3819587)
Affinity DataKd:  1.40nMAssay Description:Binding affinity to recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3) by surface plasmon resonance ...More data for this Ligand-Target Pair
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50180850(CHEMBL3819587)
Affinity DataKd:  1.60nMAssay Description:Binding affinity to recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3) assessed as dissociation rate...More data for this Ligand-Target Pair
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50539552(CHEMBL4634531)
Affinity DataKd:  1.90nMAssay Description:Binding affinity to Keap1 (unknown origin) by SPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50519234(CHEMBL4440989)
Affinity DataKd:  2.30nMAssay Description:Binding affinity to recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3) assessed as dissociation rate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50539562(CHEMBL4642419)
Affinity DataKd:  2.70nMAssay Description:Binding affinity to Keap1 (unknown origin) by SPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50006932(CHEMBL3237245)
Affinity DataKd:  3.60nMAssay Description:Binding affinity to biotinylated Keap1 DC domain (unknown origin) by biolayer interferometry assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50262955(CHEMBL4077198)
Affinity DataKd:  4.40nMAssay Description:Binding affinity to recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3) assessed as dissociation rate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50283797(CHEMBL4169002)
Affinity DataKd:  6.20nMAssay Description:Binding affinity to human biotin-labeled Keap1 Kelch domain (322 to 609 residues) expressed in Escherichia coli (DE3) by biolayer interferometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50200466(CHEMBL3913014)
Affinity DataKd:  10nMAssay Description:Binding affinity to Keap1 (unknown origin) Kelch domain by ITC assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50539569(CHEMBL4635041)
Affinity DataKd:  14nMAssay Description:Binding affinity to Keap1 (unknown origin) by SPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50006930(CHEMBL3237244)
Affinity DataKd:  16nMAssay Description:Binding affinity to biotinylated Keap1 DC domain (unknown origin) by biolayer interferometry assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50283797(CHEMBL4169002)
Affinity DataKd:  18nMAssay Description:Binding affinity to human Keap1 Kelch domain (322 to 609 residues) expressed in Escherichia coli (DE3) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50519234(CHEMBL4440989)
Affinity DataKd:  19nMAssay Description:Binding affinity to recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3) by surface plasmon resonance ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50006932(CHEMBL3237245)
Affinity DataKd:  20nMAssay Description:Binding affinity to Keap1 Kelch domain (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50006932(CHEMBL3237245)
Affinity DataKd:  20nMAssay Description:Inhibition of Keap1-Nrf2 (unknown origin) protein-protein interaction by SPR assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50006933(CHEMBL3134422)
Affinity DataKd:  21nMAssay Description:Binding affinity to recombinant human Keap1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21(DE3)pLysS by SPR-based solution com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50539556(CHEMBL4640695)
Affinity DataKd:  21nMAssay Description:Binding affinity to Keap1 (unknown origin) by SPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50283796(CHEMBL4174405)
Affinity DataKd:  21nMAssay Description:Binding affinity to human biotin-labeled Keap1 Kelch domain (322 to 609 residues) expressed in Escherichia coli (DE3) by biolayer interferometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50532963(CHEMBL4545736)
Affinity DataKd:  22nMAssay Description:Binding affinity to human KEAP1 kelch domain (322 to 609 residues) expressed in Escherichia coli Arctic(DE3) cells by biolayer interferometry methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50532963(CHEMBL4545736)
Affinity DataKd:  22nMAssay Description:Binding affinity to human KEAP1 kelch domain (322 to 609 residues) expressed in Escherichia coli Arctic(DE3) cells by biolayer interferometry methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50295169(CHEMBL4177337)
Affinity DataKd:  23nMAssay Description:Binding affinity to human Keap1 (322 to 609 residues) by ITC methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM415709(Ac-LDEETGEFL-OH | US10442759, Compound Nrf2 9mer ...)
Affinity DataKd:  23nMAssay Description:Binding affinity to recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3) by surface plasmon resonance ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM415702(US10442759, Compound I-14)
Affinity DataKd:  24nMAssay Description:Binding affinity to purified Keap1 Kelch domain (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50130558(CHEMBL3632891)
Affinity DataKd:  25nMAssay Description:Binding affinity to the Keap1 (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50200472(CHEMBL3966742)
Affinity DataKd:  26nMAssay Description:Binding affinity to recombinant human Keap1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21(DE3)pLysS by fluorescence polarizat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50006930(CHEMBL3237244)
Affinity DataKd:  26nMAssay Description:Binding affinity to recombinant human Keap1 Kelch domain (321 to 609) expressed in Escherichia coli BL21(DE3)pLysS cells after 30 mins by fluorescenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50262955(CHEMBL4077198)
Affinity DataKd:  26nMAssay Description:Binding affinity to recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3) by surface plasmon resonance ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50547100(CHEMBL4739983)
Affinity DataKd:  26nMAssay Description:Binding affinity to biotinylated human recombinant Keap1 Kelch domain (321 to 609 residues) expressed in Escherichia coli DE3 by biolayer interferome...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50584857(CHEMBL5089816)
Affinity DataKd:  27nMAssay Description:Binding affinity to Keap1 (unknown origin) at R415 assessed as dissociation constant by surface plasmon resonance based direct binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50532965(CHEMBL4476281)
Affinity DataKd:  29nMAssay Description:Binding affinity to human KEAP1 kelch domain (322 to 609 residues) expressed in Escherichia coli Arctic(DE3) cells at 0.05 mM by isothermal titration...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50584861(CHEMBL5082511)
Affinity DataKd:  29nMAssay Description:Binding affinity to Keap1 (unknown origin) at R415 assessed as dissociation constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50532965(CHEMBL4476281)
Affinity DataKd:  29nMAssay Description:Binding affinity to human KEAP1 kelch domain (322 to 609 residues) expressed in Escherichia coli Arctic(DE3) cells at 0.05 mM by isothermal titration...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50584856(CHEMBL5078020)
Affinity DataKd:  29nMAssay Description:Binding affinity to Keap1 (unknown origin) at R415 assessed as dissociation constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50516724(CHEMBL4588743)
Affinity DataKd:  29nMAssay Description:Binding affinity to biotinylated human KEAP1 Kelch domain (322 to 609 residues) by biolayer interferometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50584857(CHEMBL5089816)
Affinity DataKd:  29nMAssay Description:Binding affinity to Keap1 (unknown origin) at R415 assessed as dissociation constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50584860(CHEMBL5077539)
Affinity DataKd:  33nMAssay Description:Binding affinity to Keap1 (unknown origin) at R415 assessed as dissociation constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM304768(3-(3-((1,1-dioxido-3,4-dihydro-2H-benzo[b][1,4,5]o...)
Affinity DataKd:  35nMAssay Description:Binding affinity to human N-terminal His6-tagged KEAP1 Kelch domain (321 to 609 residues) expressed in baculovirus infected Sf9 insect cells by isoth...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50584859(CHEMBL5070465)
Affinity DataKd:  36nMAssay Description:Binding affinity to Keap1 (unknown origin) at R415 assessed as dissociation constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM415702(US10442759, Compound I-14)
Affinity DataKd:  37nMAssay Description:Binding affinity to biotinylated-Keap1 Kelch domain (unknown origin) by biolayer interferometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50584862(CHEMBL5087851)
Affinity DataKd:  37nMAssay Description:Binding affinity to Keap1 (unknown origin) at R415 assessed as dissociation constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50006932(CHEMBL3237245)
Affinity DataKd:  39nMAssay Description:Binding affinity to Keap1 (unknown origin) expressed in Escherichia coli BL21 codon plus cells by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50109368(CHEMBL3601212)
Affinity DataKd:  40nMAssay Description:Inhibition of Keap1-Nrf2 (unknown origin) protein-protein interaction by ITC assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50584822(CHEMBL5092602)
Affinity DataKd:  41nMAssay Description:Binding affinity to Keap1 (unknown origin) at R415 assessed as dissociation constant by surface plasmon resonance based inhibition-in-solution assayMore data for this Ligand-Target Pair
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50584858(CHEMBL5070545)
Affinity DataKd:  43nMAssay Description:Binding affinity to Keap1 (unknown origin) at R415 assessed as dissociation constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50584851(CHEMBL5091126)
Affinity DataKd:  44nMAssay Description:Binding affinity to Keap1 (unknown origin) at R415 assessed as dissociation constant by surface plasmon resonance based inhibition-in-solution assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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