Compile Data Set for Download or QSAR
maximum 50k data
Found 91 of ki data for polymerid = 50001107,50001875,9427
TargetMaltase-glucoamylase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291029((2R,3R,4R,5S)-2-Hydroxymethyl-1-((E)-3-trimethylsi...)
Affinity DataKi:  2.30nMAssay Description:In vitro inhibition constant against rat small intestinal glucoamylaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMaltase-glucoamylase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291026((2R,3R,4R,5S)-1-[(E)-3-(Dimethyl-phenyl-silanyl)-a...)
Affinity DataKi:  4nMAssay Description:In vitro inhibition constant against rat small intestinal glucoamylaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM50583383(CHEMBL5028005 | US20230339856, Compound (IIb3))
Affinity DataKi:  4.70nMAssay Description:Inhibition of human GAA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 min followed by substrate addition and me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM50583382(CHEMBL5028265)
Affinity DataKi:  6.10nMAssay Description:Inhibition of human GAA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 min followed by substrate addition and me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Homo sapiens (Human))
Simon Fraser University

Curated by ChEMBL
LigandPNGBDBM50327504(1,4-Dideoxy-1,4-[[2S,3S,4R,5S]-2,4,5,6-tetrahydrox...)
Affinity DataKi:  7nMAssay Description:Inhibition of human recombinant C-terminal Sucrase-isomaltase by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291020((2R,3R,4R,5S)-1-[3-(Dimethyl-phenyl-silanyl)-propy...)
Affinity DataKi:  10nMAssay Description:In vitro inhibition constant against rat small intestinal glucoamylaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMaltase-glucoamylase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50327503((1R,2R,3S,4S)-3,4-dihydroxy-2-(hydroxymethyl)-1-((...)
Affinity DataKi:  15nMAssay Description:Inhibition of human recombinant N-terminal domain of maltase-glucoamylase after 60 mins by glucose oxidase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM50583381(CHEMBL5029066 | US20230339856, Compound (IIb1))
Affinity DataKi:  19nMAssay Description:Inhibition of human GAA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 min followed by substrate addition and me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50330961((2R,3S,4S)-1-((2S,3S,4R,5R,6S)-2,3,4,5,6,7-hexahyd...)
Affinity DataKi:  20nMAssay Description:Inhibition of human recombinant N-terminal subunit of maltase-glucoamylase after 60 mins by glucose oxidase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291027((2R,3R,4R,5S)-2-Hydroxymethyl-1-(4-trimethylsilany...)
Affinity DataKi:  28nMAssay Description:In vitro inhibition constant against rat small intestinal glucoamylaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMaltase-glucoamylase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50330954(CHEMBL1276973 | de-O-sulfonated kotalanol)
Affinity DataKi:  30nMAssay Description:Inhibition of human recombinant N-terminal subunit of maltase-glucoamylase after 60 mins by glucose oxidase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Homo sapiens (Human))
Simon Fraser University

Curated by ChEMBL
LigandPNGBDBM50327504(1,4-Dideoxy-1,4-[[2S,3S,4R,5S]-2,4,5,6-tetrahydrox...)
Affinity DataKi:  35nMAssay Description:Inhibition of human recombinant N-terminal Sucrase-isomaltase by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM50583380(CHEMBL5027974)
Affinity DataKi:  37nMAssay Description:Inhibition of human GAA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 min followed by substrate addition and me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50327502((1R,2R,3S,4S)-3,4-dihydroxy-2-(hydroxymethyl)-1-((...)
Affinity DataKi:  43nMAssay Description:Inhibition of human N-terminal maltase-glucoamylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50327502((1R,2R,3S,4S)-3,4-dihydroxy-2-(hydroxymethyl)-1-((...)
Affinity DataKi:  43nMAssay Description:Inhibition of human recombinant N-terminal domain of maltase-glucoamylase after 60 mins by glucose oxidase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291031((2R,3R,4R,5S)-2-Hydroxymethyl-1-(3-trimethylsilany...)
Affinity DataKi:  50nMAssay Description:In vitro inhibition constant against rat small intestinal glucoamylaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM50583379(CHEMBL5028138 | US20230339856, Compound (IIb))
Affinity DataKi:  59nMAssay Description:Inhibition of human GAA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 min followed by substrate addition and me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM18353((2R,3R,4R,5S)-2-(hydroxymethyl)-1-methylpiperidine...)
Affinity DataKi:  59nMAssay Description:Inhibition of human GAA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 min followed by substrate addition and me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM18351((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)
Affinity DataKi:  59nMAssay Description:Inhibition of human GAA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 min followed by substrate addition and me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50330960((2R,3R,4R)-1-((2R,3R,4S,5R,6S)-2,3,4,5,6,7-hexahyd...)
Affinity DataKi:  60nMAssay Description:Inhibition of human recombinant N-terminal subunit of maltase-glucoamylase after 60 mins by glucose oxidase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291034((2R,3R,4R,5S)-2-Hydroxymethyl-1-(5-trimethylsilany...)
Affinity DataKi:  70nMAssay Description:In vitro inhibition constant against rat small intestinal glucoamylaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMaltase-glucoamylase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50330959(CHEMBL1277153)
Affinity DataKi:  80nMAssay Description:Inhibition of human recombinant N-terminal subunit of maltase-glucoamylase after 60 mins by glucose oxidase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291023((2R,3R,4R,5S)-1-[(E)-3-(tert-Butyl-dimethyl-silany...)
Affinity DataKi:  87nMAssay Description:In vitro inhibition constant against rat small intestinal glucoamylaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM50335398(CHEMBL1651551 | N-Heptyl-1-deoxynojirimycin)
Affinity DataKi:  95nMAssay Description:Inhibition of human GAA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 min followed by substrate addition and me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50316180((1S,2R,3S,4S)-1-{(1S)-2-[(2R,3S,4S)-3,4-dihydroxy-...)
Affinity DataKi:  100nMAssay Description:Inhibition of recombinant human maltase glucoamylase N-terminal catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Homo sapiens (Human))
Simon Fraser University

Curated by ChEMBL
LigandPNGBDBM50327502((1R,2R,3S,4S)-3,4-dihydroxy-2-(hydroxymethyl)-1-((...)
Affinity DataKi:  103nMAssay Description:Inhibition of human recombinant C-terminal Sucrase-isomaltase by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291021((2R,3R,4R,5S)-2-Hydroxymethyl-1-(4-trimethylsilany...)
Affinity DataKi:  120nMAssay Description:In vitro inhibition constant against rat small intestinal glucoamylaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMaltase-glucoamylase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50316181((1S,2R,3S,4R)-1-{(1S)-2-[(2R,3S,4S)-3,4-dihydroxy-...)
Affinity DataKi:  130nMAssay Description:Inhibition of recombinant human maltase glucoamylase N-terminal catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM18356((2R,3R,4R,5S)-1-hexyl-2-(hydroxymethyl)piperidine-...)
Affinity DataKi:  130nMAssay Description:Inhibition of human GAA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 min followed by substrate addition and me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM18351((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)
Affinity DataKi:  150nMAssay Description:Tested in vitro for the inhibition constant against human lysosomal alpha-glucosidaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMaltase-glucoamylase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50327501(CHEMBL1258528 | ponkoranol)
Affinity DataKi:  170nMAssay Description:Inhibition of human recombinant N-terminal domain of maltase-glucoamylase after 60 mins by glucose oxidase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50316179((1S,2R,3R,4S)-1-{(1S)-2-[(2R,3S,4S)-3,4-dihydroxy-...)
Affinity DataKi:  190nMAssay Description:Inhibition of recombinant human maltase glucoamylase N-terminal catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50330955((1S,2S)-3-[(2R,3S,4S)-3,4-dihydroxy-2-(hydroxymeth...)
Affinity DataKi:  190nMAssay Description:Inhibition of recombinant human maltase-glucoamylase using p-nitrophenyl-alpha-D-glucopyranoside as substrate incubated for 35 mins by microtiter pla...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50316179((1S,2R,3R,4S)-1-{(1S)-2-[(2R,3S,4S)-3,4-dihydroxy-...)
Affinity DataKi:  190nMAssay Description:Inhibition of human recombinant N-terminal subunit of maltase-glucoamylase after 60 mins by glucose oxidase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50316178(1,4-Dideoxy-1,4-[[2S,3S,4R,5R,6R-2,4,5,6,7-pentahy...)
Affinity DataKi:  200nMAssay Description:Inhibition of recombinant human maltase glucoamylase N-terminal catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM18355((2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-...)
Affinity DataKi:  200nMAssay Description:Inhibition of human GAA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 min followed by substrate addition and me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM50335399(CHEMBL1651549 | N-Pentyl-1-deoxynojirimycin)
Affinity DataKi:  210nMAssay Description:Inhibition of human GAA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 min followed by substrate addition and me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM50583384(CHEMBL5080975)
Affinity DataKi:  210nMAssay Description:Inhibition of human GAA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 min followed by substrate addition and me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Homo sapiens (Human))
Simon Fraser University

Curated by ChEMBL
LigandPNGBDBM50327502((1R,2R,3S,4S)-3,4-dihydroxy-2-(hydroxymethyl)-1-((...)
Affinity DataKi:  302nMAssay Description:Inhibition of human recombinant N-terminal Sucrase-isomaltase by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM18354((2R,3R,4R,5S)-2-(hydroxymethyl)-1-propylpiperidine...)
Affinity DataKi:  360nMAssay Description:Inhibition of human GAA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 min followed by substrate addition and me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM18353((2R,3R,4R,5S)-2-(hydroxymethyl)-1-methylpiperidine...)
Affinity DataKi:  420nMAssay Description:Tested in vitro for the inhibition constant against human lysosomal alpha-glucosidaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMaltase-glucoamylase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50408432(CHEMBL2115215)
Affinity DataKi:  450nMAssay Description:Compound was tested for binding affinity against alpha-glucosidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50327504(1,4-Dideoxy-1,4-[[2S,3S,4R,5S]-2,4,5,6-tetrahydrox...)
Affinity DataKi:  500nMAssay Description:Inhibition of human N-terminal maltase-glucoamylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50327504(1,4-Dideoxy-1,4-[[2S,3S,4R,5S]-2,4,5,6-tetrahydrox...)
Affinity DataKi:  500nMAssay Description:Inhibition of human recombinant N-terminal maltase-glucoamylase by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50327504(1,4-Dideoxy-1,4-[[2S,3S,4R,5S]-2,4,5,6-tetrahydrox...)
Affinity DataKi:  500nMAssay Description:Inhibition of human recombinant N-terminal domain of maltase-glucoamylase after 60 mins by glucose oxidase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291028((2R,3R,4R,5S)-1-(Dimethyl-propyl-silanylmethyl)-2-...)
Affinity DataKi:  900nMAssay Description:In vitro inhibition constant against rat small intestinal glucoamylaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMaltase-glucoamylase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50330955((1S,2S)-3-[(2R,3S,4S)-3,4-dihydroxy-2-(hydroxymeth...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of human recombinant N-terminal subunit of maltase-glucoamylase after 60 mins by glucose oxidase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50242271((2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of human recombinant N-terminal subunit of maltase-glucoamylase after 60 mins by glucose oxidase assayMore data for this Ligand-Target Pair
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM50291029((2R,3R,4R,5S)-2-Hydroxymethyl-1-((E)-3-trimethylsi...)
Affinity DataKi:  1.00E+3nMAssay Description:Tested in vitro for the inhibition constant against human lysosomal alpha-glucosidaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMaltase-glucoamylase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291032((2R,3R,4R,5S)-2-Hydroxymethyl-1-(3-trimethylsilany...)
Affinity DataKi:  1.00E+3nMAssay Description:In vitro inhibition constant against rat small intestinal glucoamylaseMore data for this Ligand-Target Pair
In DepthDetails Article
Displayed 1 to 50 (of 91 total ) | Next | Last >>
Jump to: