Compile Data Set for Download or QSAR
maximum 50k data
Found 11 of ki data for polymerid = 50007085
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
North-West University

Curated by ChEMBL
LigandPNGBDBM50174181(CHEMBL3809806)
Affinity DataKi:  490nMAssay Description:Mixed type inhibition of Klebsiella pneumoniae metallo-beta-lactamase NDM-1 expressed in Escherichia coli BL21(DE3) cells assessed as hydrolysis of c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
North-West University

Curated by ChEMBL
LigandPNGBDBM50131078(3-formylchromones | 4-Oxo-4H-chromene-3-carbaldehy...)
Affinity DataKi:  580nMAssay Description:Time-dependent inhibition of wild type Klebsiella pneumoniae 6xHis-tagged metallo-beta-lactamase NDM-1 expressed in Escherichia coli BL21 (DE3)pLysSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
North-West University

Curated by ChEMBL
LigandPNGBDBM50174175(CHEMBL3808813)
Affinity DataKi:  630nMAssay Description:Mixed type inhibition of Klebsiella pneumoniae metallo-beta-lactamase NDM-1 expressed in Escherichia coli BL21(DE3) cells assessed as hydrolysis of c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
North-West University

Curated by ChEMBL
LigandPNGBDBM50452815(CHEMBL2005280)
Affinity DataKi:  5.11E+3nMAssay Description:Non-competitive inhibition of NDM1 in Escherichia coli BL21 (DE3) using MEPM substrate incubated for 15 mins by UV spectroscopy based L-B plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
North-West University

Curated by ChEMBL
LigandPNGBDBM50452814(CHEMBL4212352)
Affinity DataKi:  5.63E+3nMAssay Description:Non-competitive inhibition of NDM1 in Escherichia coli BL21 (DE3) using MEPM substrate incubated for 15 mins by UV spectroscopy based L-B plotMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
North-West University

Curated by ChEMBL
LigandPNGBDBM50548231(CHEMBL4753599)
Affinity DataKi:  1.70E+4nMAssay Description:Inhibition of wild type N-terminal His6-tagged Klebsiella pneumoniae NDM-1 expressed in Escherichia coli BL21 assessed as inhibition constant using n...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
North-West University

Curated by ChEMBL
LigandPNGBDBM426626(US10543221, Compound 994942 | US10543221, Formula ...)
Affinity DataKi:  5.50E+4nMAssay Description:Expression and Purification of Beta-Lactamases. For his tag KPC-2 beta-lactamase, bacteria were grown overnight at 30 C with shaking in 50 mL LB brot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
North-West University

Curated by ChEMBL
LigandPNGBDBM50131078(3-formylchromones | 4-Oxo-4H-chromene-3-carbaldehy...)
Affinity DataKi:  7.60E+4nMAssay Description:Time-dependent inhibition of wild type Klebsiella pneumoniae 6xHis-tagged metallo-beta-lactamase NDM-1 expressed in Escherichia coli BL21 (DE3)pLysS ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
North-West University

Curated by ChEMBL
LigandPNGBDBM426620(US10543221, Compound 72588 | US10543221, Formula )
Affinity DataKi:  1.00E+5nMAssay Description:Expression and Purification of Beta-Lactamases. For his tag KPC-2 beta-lactamase, bacteria were grown overnight at 30 C with shaking in 50 mL LB brot...More data for this Ligand-Target Pair
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
North-West University

Curated by ChEMBL
LigandPNGBDBM50129065(CHEMBL3278535)
Affinity DataKi:  1.86E+5nMAssay Description:Competitive inhibition of His-tagged Klebsiella pneumoniae NDM-1 expressed in Escherichia coli BL21-AI cells using imipinem as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
North-West University

Curated by ChEMBL
LigandPNGBDBM50129065(CHEMBL3278535)
Affinity DataKi:  1.86E+5nMAssay Description:Competitive inhibition of His-tagged Klebsiella pneumoniae NDM-1 expressed in Escherichia coli BL21-AI cells using imipinem as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed