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Found 275 Enz. Inhib. hit(s) with Target = '1,3-beta-glucan synthase'
Target1,3-beta-glucan synthase(Candida glabrata)
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50503148(CHEMBL4583809)
Affinity DataEC50:  2.43E+3nMAssay Description:Positive allosteric modulation of GluN2A receptor (unknown origin) expressed in HEK cell assessed as increase in glycine-induced calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida glabrata)
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50503147(CHEMBL4435232)
Affinity DataEC50:  3.20E+3nMAssay Description:Positive allosteric modulation of GluN2A receptor (unknown origin) expressed in xenopus laevis oocytes assessed as increase in glycine-induced channe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase component GSC2(Saccharomyces cerevisiae)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50499726(CHEMBL3742181)
Affinity DataEC50:  4.60E+3nMAssay Description:Induction of dissociation of [3H]-dofetilide from Kv11.1 channel (unknown origin) assessed as dissociation rate expressed in HEK293 cells after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida glabrata)
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50503143(CHEMBL4515734)
Affinity DataEC50:  8.50E+3nMAssay Description:Positive allosteric modulation of GluN2A receptor (unknown origin) expressed in xenopus laevis oocytes assessed as increase in glycine-induced channe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida glabrata)
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50436060(CHEMBL2397100 | US10273214, Example 1390)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of GluN2A receptor (unknown origin) expressed in xenopus laevis oocytes assessed as increase in glycine-induced channe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase component GSC2(Saccharomyces cerevisiae)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50499725(CHEMBL3740963)
Affinity DataEC50:  1.20E+4nMAssay Description:Induction of dissociation of [3H]-dofetilide from Kv11.1 channel (unknown origin) assessed as dissociation rate expressed in HEK293 cells after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida glabrata)
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50503144(CHEBI:35420 | CHEMBL1179605)
Affinity DataEC50:  2.10E+4nMAssay Description:Positive allosteric modulation of GluN2A receptor (unknown origin) expressed in xenopus laevis oocytes assessed as increase in glycine-induced channe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida glabrata)
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50503152(CHEMBL4452216)
Affinity DataEC50:  2.80E+4nMAssay Description:Positive allosteric modulation of GluN2A receptor (unknown origin) expressed in xenopus laevis oocytes assessed as increase in glycine-induced channe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida glabrata)
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50503144(CHEBI:35420 | CHEMBL1179605)
Affinity DataEC50:  3.40E+4nMAssay Description:Positive allosteric modulation of EGFP-fused human GluN2A receptor expressed in HEK293T cells assessed as increase in glycine-induced channel current...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida glabrata)
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50503145(CHEMBL4456824)
Affinity DataEC50:  1.00E+5nMAssay Description:Positive allosteric modulation of GluN2A receptor (unknown origin) expressed in xenopus laevis oocytes assessed as increase in glycine-induced channe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase component GSC2(Saccharomyces cerevisiae)
Leiden University

Curated by ChEMBL
LigandPNGBDBM97255(2-(1-bromanylnaphthalen-2-yl)oxy-N-pyridin-3-yl-et...)
Affinity DataKi:  4.80nMAssay Description:Binding affinity to Kv11.1 channel (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Ucb Pharma

US Patent
LigandPNGBDBM111590(US8624022, OGT4325)
Affinity DataIC50:  8.50E+3nMpH: 8.0 T: 2°CAssay Description:The glucan synthase assay follows the incorporation of tritiated UDP-glucose into acid insoluble β-glucan as catalysed by the glucan synthase ac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Ucb Pharma

US Patent
LigandPNGBDBM111591(US8624022, OGT4355)
Affinity DataIC50:  1.50E+4nMpH: 8.0 T: 2°CAssay Description:The glucan synthase assay follows the incorporation of tritiated UDP-glucose into acid insoluble β-glucan as catalysed by the glucan synthase ac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Ucb Pharma

US Patent
LigandPNGBDBM111592(US8624022, OGT4344)
Affinity DataIC50:  3.40E+4nMpH: 8.0 T: 2°CAssay Description:The glucan synthase assay follows the incorporation of tritiated UDP-glucose into acid insoluble β-glucan as catalysed by the glucan synthase ac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Ucb Pharma

US Patent
LigandPNGBDBM111593(US8624022, OGT4165)
Affinity DataIC50:  2.70E+3nMpH: 8.0 T: 2°CAssay Description:The glucan synthase assay follows the incorporation of tritiated UDP-glucose into acid insoluble β-glucan as catalysed by the glucan synthase ac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Ucb Pharma

US Patent
LigandPNGBDBM111594(US8624022, OGT4154)
Affinity DataIC50:  8.00E+3nMpH: 8.0 T: 2°CAssay Description:The glucan synthase assay follows the incorporation of tritiated UDP-glucose into acid insoluble β-glucan as catalysed by the glucan synthase ac...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Ucb Pharma

US Patent
LigandPNGBDBM111595(US8624022, OGT4155)
Affinity DataIC50:  5.40E+3nMpH: 8.0 T: 2°CAssay Description:The glucan synthase assay follows the incorporation of tritiated UDP-glucose into acid insoluble β-glucan as catalysed by the glucan synthase ac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Ucb Pharma

US Patent
LigandPNGBDBM111596(US8624022, OGT3935)
Affinity DataIC50:  1.20E+4nMpH: 8.0 T: 2°CAssay Description:The glucan synthase assay follows the incorporation of tritiated UDP-glucose into acid insoluble β-glucan as catalysed by the glucan synthase ac...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target1,3-beta-glucan synthase(Neosartorya fumigata (Aspergillus fumigatus))
Ucb Pharma

US Patent
LigandPNGBDBM111590(US8624022, OGT4325)
Affinity DataIC50:  1.56E+4nMpH: 8.0 T: 2°CAssay Description:The glucan synthase assay follows the incorporation of tritiated UDP-glucose into acid insoluble β-glucan as catalysed by the glucan synthase ac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target1,3-beta-glucan synthase(Neosartorya fumigata (Aspergillus fumigatus))
Ucb Pharma

US Patent
LigandPNGBDBM111591(US8624022, OGT4355)
Affinity DataIC50:  2.30E+4nMpH: 8.0 T: 2°CAssay Description:The glucan synthase assay follows the incorporation of tritiated UDP-glucose into acid insoluble β-glucan as catalysed by the glucan synthase ac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target1,3-beta-glucan synthase(Neosartorya fumigata (Aspergillus fumigatus))
Ucb Pharma

US Patent
LigandPNGBDBM111592(US8624022, OGT4344)
Affinity DataIC50:  4.90E+4nMpH: 8.0 T: 2°CAssay Description:The glucan synthase assay follows the incorporation of tritiated UDP-glucose into acid insoluble β-glucan as catalysed by the glucan synthase ac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target1,3-beta-glucan synthase(Neosartorya fumigata (Aspergillus fumigatus))
Ucb Pharma

US Patent
LigandPNGBDBM111593(US8624022, OGT4165)
Affinity DataIC50:  6.20E+3nMpH: 8.0 T: 2°CAssay Description:The glucan synthase assay follows the incorporation of tritiated UDP-glucose into acid insoluble β-glucan as catalysed by the glucan synthase ac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target1,3-beta-glucan synthase(Neosartorya fumigata (Aspergillus fumigatus))
Ucb Pharma

US Patent
LigandPNGBDBM111594(US8624022, OGT4154)
Affinity DataIC50:  5.60E+3nMpH: 8.0 T: 2°CAssay Description:The glucan synthase assay follows the incorporation of tritiated UDP-glucose into acid insoluble β-glucan as catalysed by the glucan synthase ac...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target1,3-beta-glucan synthase(Neosartorya fumigata (Aspergillus fumigatus))
Ucb Pharma

US Patent
LigandPNGBDBM111595(US8624022, OGT4155)
Affinity DataIC50:  5.20E+3nMpH: 8.0 T: 2°CAssay Description:The glucan synthase assay follows the incorporation of tritiated UDP-glucose into acid insoluble β-glucan as catalysed by the glucan synthase ac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target1,3-beta-glucan synthase(Neosartorya fumigata (Aspergillus fumigatus))
Ucb Pharma

US Patent
LigandPNGBDBM111596(US8624022, OGT3935)
Affinity DataIC50:  3.80E+4nMpH: 8.0 T: 2°CAssay Description:The glucan synthase assay follows the incorporation of tritiated UDP-glucose into acid insoluble β-glucan as catalysed by the glucan synthase ac...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Ucb Pharma

US Patent
LigandPNGBDBM50451308(CHEMBL2370657)
Affinity DataIC50:  19nMAssay Description:Inhibition of 1,3-beta-D-glucan synthase (GS) from candida albicansMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Ucb Pharma

US Patent
LigandPNGBDBM50096793(CHEMBL2370666 | macrocyclic lipopeptidolactone der...)
Affinity DataIC50:  6nMAssay Description:Inhibition of 1,3-beta-D-glucan synthase (GS) from candida albicansMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Ucb Pharma

US Patent
LigandPNGBDBM50096794(CHEMBL2370668 | macrocyclic lipopeptidolactone der...)
Affinity DataIC50:  24nMAssay Description:Inhibition of 1,3-beta-D-glucan synthase (GS) from candida albicansMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Ucb Pharma

US Patent
LigandPNGBDBM50096797(CHEMBL2370665 | macrocyclic lipopeptidolactone der...)
Affinity DataIC50:  2nMAssay Description:Inhibition of 1,3-beta-D-glucan synthase (GS) from candida albicansMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Ucb Pharma

US Patent
LigandPNGBDBM50096796(CHEMBL2370667 | macrocyclic lipopeptidolactone der...)
Affinity DataIC50: >520nMAssay Description:Inhibition of 1,3-beta-D-glucan synthase (GS) from candida albicansMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Ucb Pharma

US Patent
LigandPNGBDBM50096798(CHEMBL2370655 | macrocyclic lipopeptidolactone der...)
Affinity DataIC50:  12nMAssay Description:Inhibition of 1,3-beta-D-glucan synthase (GS) from candida albicansMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Ucb Pharma

US Patent
LigandPNGBDBM50096799(CHEMBL2369134 | macrocyclic lipopeptidolactone der...)
Affinity DataIC50:  8nMAssay Description:Inhibition of 1,3-beta-D-glucan synthase (GS) from candida albicansMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Ucb Pharma

US Patent
LigandPNGBDBM50096800(CHEMBL2370652 | macrocyclic lipopeptidolactone der...)
Affinity DataIC50:  20nMAssay Description:Inhibition of 1,3-beta-D-glucan synthase (GS) from candida albicansMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Ucb Pharma

US Patent
LigandPNGBDBM50096802(CHEMBL2370656 | macrocyclic lipopeptidolactone der...)
Affinity DataIC50: >130nMAssay Description:Inhibition of 1,3-beta-D-glucan synthase (GS) from candida albicansMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Ucb Pharma

US Patent
LigandPNGBDBM50096795(CHEMBL2370654 | Macrocyclic lipopeptidolactone der...)
Affinity DataIC50:  5nMAssay Description:Inhibition of 1,3-beta-D-glucan synthase (GS) from candida albicansMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Ucb Pharma

US Patent
LigandPNGBDBM50096801(CHEMBL2370651 | macrocyclic lipopeptidolactone der...)
Affinity DataIC50:  230nMAssay Description:Inhibition of 1,3-beta-D-glucan synthase (GS) from candida albicansMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Ucb Pharma

US Patent
LigandPNGBDBM50096803(CHEMBL2370664 | macrocyclic lipopeptidolactone der...)
Affinity DataIC50:  45nMAssay Description:Inhibition of 1,3-beta-D-glucan synthase (GS) from candida albicansMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Ucb Pharma

US Patent
LigandPNGBDBM50043897(10,12-Dimethyl-tetradecanoic acid [3-(2-carbamoyl-...)
Affinity DataIC50:  70nMAssay Description:Tested for inhibition of Beta-1,3-glucan synthase using a crude membrane of Candida albicans (MY 1208).More data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Ucb Pharma

US Patent
LigandPNGBDBM50285475(1N-[23-[1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl]-20...)
Affinity DataIC50:  9nMAssay Description:Tested for inhibition of Beta-1,3-glucan synthase using a crude membrane of Candida albicans (MY 1208).More data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Ucb Pharma

US Patent
LigandPNGBDBM50285476(10,12-Dimethyl-tetradecanoic acid {11,20,25-trihyd...)
Affinity DataIC50:  80nMAssay Description:Tested for inhibition of Beta-1,3-glucan synthase using a crude membrane of Candida albicans (MY 1208).More data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Ucb Pharma

US Patent
LigandPNGBDBM50285477(1N-{20-[2-(5-carboxycarbamoyl)-1-hydroxyethyl]-2,1...)
Affinity DataIC50:  900nMAssay Description:Tested for inhibition of Beta-1,3-glucan synthase using a crude membrane of Candida albicans (MY 1208).More data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Ucb Pharma

US Patent
LigandPNGBDBM50285478(1N-{20-[2-(6-aminohexylcarbamoyl)-1-hydroxyethyl]-...)
Affinity DataIC50:  38nMAssay Description:Tested for inhibition of Beta-1,3-glucan synthase using a crude membrane of Candida albicans (MY 1208).More data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Ucb Pharma

US Patent
LigandPNGBDBM50285479(10,12-Dimethyl-tetradecanoic acid [6-[1,2-dihydrox...)
Affinity DataIC50:  7nMAssay Description:Tested for inhibition of Beta-1,3-glucan synthase using a crude membrane of Candida albicans (MY 1208).More data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Ucb Pharma

US Patent
LigandPNGBDBM50285480(10,12-Dimethyl-tetradecanoic acid {3-(2-cyano-1-hy...)
Affinity DataIC50:  100nMAssay Description:Tested for inhibition of Beta-1,3-glucan synthase using a crude membrane of Candida albicans (MY 1208).More data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Ucb Pharma

US Patent
LigandPNGBDBM50285481(10,12-Dimethyl-tetradecanoic acid {3-(3-amino-1-hy...)
Affinity DataIC50:  10nMAssay Description:Tested for inhibition of Beta-1,3-glucan synthase using a crude membrane of Candida albicans (MY 1208).More data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Ucb Pharma

US Patent
LigandPNGBDBM50285482(3-{18-(10,12-Dimethyl-tetradecanoylamino)-11,20,25...)
Affinity DataIC50:  400nMAssay Description:Tested for inhibition of Beta-1,3-glucan synthase using a crude membrane of Candida albicans (MY 1208).More data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Ucb Pharma

US Patent
LigandPNGBDBM50285483(10,12-Dimethyl-tetradecanoic acid [3-(3-acetylamin...)
Affinity DataIC50:  300nMAssay Description:Tested for inhibition of Beta-1,3-glucan synthase using a crude membrane of Candida albicans (MY 1208).More data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Ucb Pharma

US Patent
LigandPNGBDBM50285484(10,12-Dimethyl-tetradecanoic acid {3-(1,3-dihydrox...)
Affinity DataIC50:  200nMAssay Description:Tested for inhibition of Beta-1,3-glucan synthase using a crude membrane of Candida albicans (MY 1208).More data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Ucb Pharma

US Patent
LigandPNGBDBM50285485(10,12-Dimethyl-tetradecanoic acid [11,20,25-trihyd...)
Affinity DataIC50:  120nMAssay Description:Tested for inhibition of Beta-1,3-glucan synthase using a crude membrane of Candida albicans (MY 1208).More data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Ucb Pharma

US Patent
LigandPNGBDBM50285486(1N-{20-[2-(5-carboxymethylcarbamoyl)-1-hydroxyethy...)
Affinity DataIC50:  250nMAssay Description:Tested for inhibition of Beta-1,3-glucan synthase using a crude membrane of Candida albicans (MY 1208).More data for this Ligand-Target Pair
In DepthDetails Article
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