TargetCaspase-1/Caspase-10/Caspase-14/Caspase-2/Caspase-3/Caspase-4/Caspase-5/Caspase-6/Caspase-7/Caspase-8/Caspase-9/Inactive caspase-12(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataEC50: 16nMAssay Description:Activation of caspase cascade in human T47D cells using N-(Ac-DEVD)-N'-ethoxycarbonyl-R110 fluorogenic substrate incubated for 48 hrs by fluorescent ...More data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+3nMAssay Description:Inhibition of human recombinant caspase 1 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+3nMAssay Description:Inhibition of human recombinant caspase 1 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+3nMAssay Description:Inhibition of human recombinant caspase 1 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+3nMAssay Description:Inhibition of human recombinant caspase 1 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+3nMAssay Description:Inhibition of human recombinant caspase 1 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+3nMAssay Description:Inhibition of human recombinant caspase 1 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+3nMAssay Description:Inhibition of human recombinant caspase 1 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+3nMAssay Description:Inhibition of human recombinant caspase 1 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+3nMAssay Description:Inhibition of human recombinant caspase 1 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+3nMAssay Description:Inhibition of human recombinant caspase 1 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+3nMAssay Description:Inhibition of human recombinant caspase 1 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+3nMAssay Description:Inhibition of human recombinant caspase 1 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+3nMAssay Description:Inhibition of human recombinant caspase 1 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+3nMAssay Description:Inhibition of human recombinant caspase 1 assessed as accumulation of 7-amino-4-methylcoumarin substrateMore data for this Ligand-Target Pair
Affinity DataKi: 0.150nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
Affinity DataKi: 0.150nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
Affinity DataKi: 0.370nMAssay Description:Inhibition of human recombinant IL-1 beta converting enzymeMore data for this Ligand-Target Pair
Affinity DataKi: 0.370nMAssay Description:The binding affinity against IL-1 beta converting enzymeChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.580nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
Affinity DataKi: 0.760nMAssay Description:Inhibition of human recombinant IL-1 beta converting enzymeMore data for this Ligand-Target Pair
Affinity DataKi: 0.760nMAssay Description:The compound was tested for inhibition of IL-1 beta converting enzyme in whole human blood.More data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibition of caspase 1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.850nMAssay Description:Inhibition of human recombinant IL-1 beta converting enzymeMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
Affinity DataKi: 0.950nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Reversible Inhibition constants of the compound against IL-1 beta converting enzyme (ICE)More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Reversible Inhibition constants of the compound against IL-1 beta converting enzyme (ICE)More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibition of human recombinant IL-1 beta converting enzymeMore data for this Ligand-Target Pair
Affinity DataKi: 1.26nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
Affinity DataKi: 1.29nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:The binding affinity against IL-1 beta converting enzymeChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 1.31nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Inhibition of human recombinant IL-1 beta converting enzymeMore data for this Ligand-Target Pair
Affinity DataKi: 1.81nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair