Compile Data Set for Download or QSAR
maximum 50k data
Found 158 Enz. Inhib. hit(s) with Target = 'Cytochrome c'
TargetCytochrome c(Homo sapiens)
Instituto De Qu£Mica Avanzada De Catalu£A

Curated by ChEMBL
LigandPNGBDBM50486083(CHEMBL2203815)
Affinity DataEC50:  1.40E+4nMAssay Description:Inhibition of Apaf-1-caspase 9-cytochrome c-caspase 3 complex in human HEK293 cytosolic extract using afc-DEVD as substrate preincubated for 30 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome c(Homo sapiens)
Instituto De Qu£Mica Avanzada De Catalu£A

Curated by ChEMBL
LigandPNGBDBM50486085(CHEMBL2203816)
Affinity DataEC50:  1.44E+4nMAssay Description:Inhibition of Apaf-1-caspase 9-cytochrome c-caspase 3 complex in human HEK293 cytosolic extract using afc-DEVD as substrate preincubated for 30 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome c(Homo sapiens)
Instituto De Qu£Mica Avanzada De Catalu£A

Curated by ChEMBL
LigandPNGBDBM50486084(CHEMBL252122)
Affinity DataEC50:  1.68E+4nMAssay Description:Inhibition of Apaf-1-caspase 9-cytochrome c-caspase 3 complex in human HEK293 cytosolic extract using afc-DEVD as substrate preincubated for 30 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome c(Homo sapiens)
Instituto De Qu£Mica Avanzada De Catalu£A

Curated by ChEMBL
LigandPNGBDBM50486086(CHEMBL2203814)
Affinity DataEC50:  1.70E+4nMAssay Description:Inhibition of Apaf-1-caspase 9-cytochrome c-caspase 3 complex in human HEK293 cytosolic extract using afc-DEVD as substrate preincubated for 30 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome c(Homo sapiens)
Instituto De Qu£Mica Avanzada De Catalu£A

Curated by ChEMBL
LigandPNGBDBM50486081(CHEMBL2203812)
Affinity DataEC50:  2.39E+4nMAssay Description:Inhibition of Apaf-1-caspase 9-cytochrome c-caspase 3 complex in human HEK293 cytosolic extract using afc-DEVD as substrate preincubated for 30 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome c(Homo sapiens)
Instituto De Qu£Mica Avanzada De Catalu£A

Curated by ChEMBL
LigandPNGBDBM50486082(CHEMBL2203813)
Affinity DataEC50:  2.99E+4nMAssay Description:Inhibition of Apaf-1-caspase 9-cytochrome c-caspase 3 complex in human HEK293 cytosolic extract using afc-DEVD as substrate preincubated for 30 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome c oxidase subunit 2(Homo sapiens (Human))
Dpsr University

Curated by ChEMBL
LigandPNGBDBM50587911(CHEMBL5183049)
Affinity DataKi:  9.46E+4nMAssay Description:Binding affinity to human recombinant COX-2 assessed as inhibition constant preincubated for 5 mins followed by arachidonic acid addition measured ev...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCytochrome c oxidase subunit 2(Homo sapiens (Human))
Dpsr University

Curated by ChEMBL
LigandPNGBDBM13063(4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)benzene-1-sul...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human recombinant cyclooxygenase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome c oxidase subunit 1(Ovis aries)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM13063(4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)benzene-1-sul...)
Affinity DataIC50:  9.62E+4nMAssay Description:Inhibition of ovine cyclooxygenase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome c oxidase subunit 2(Homo sapiens (Human))
Dpsr University

Curated by ChEMBL
LigandPNGBDBM50229774(CHEMBL254418 | N-Hydroxy-4-(5-methyl-3-phenylisoxa...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human recombinant cyclooxygenase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome c oxidase subunit 1(Ovis aries)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50229774(CHEMBL254418 | N-Hydroxy-4-(5-methyl-3-phenylisoxa...)
Affinity DataIC50:  1.57E+5nMAssay Description:Inhibition of ovine cyclooxygenase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome c oxidase subunit 1(Ovis aries)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50326826(2-(4-acetamido)phenyl)-8-benzoyl-quinoline-4-carbo...)
Affinity DataIC50:  9.20E+3nMAssay Description:Inhibition of sheep COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome c oxidase subunit 2(Ovis aries)
Shahid Beheshti University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50326826(2-(4-acetamido)phenyl)-8-benzoyl-quinoline-4-carbo...)
Affinity DataIC50:  80nMAssay Description:Inhibition of sheep COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome c oxidase subunit 1(Ovis aries)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50326827(2-(4-acetamido)phenyl)-6-benzoyl-quinoline-4-carbo...)
Affinity DataIC50:  2.18E+4nMAssay Description:Inhibition of sheep COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome c oxidase subunit 2(Ovis aries)
Shahid Beheshti University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50326827(2-(4-acetamido)phenyl)-6-benzoyl-quinoline-4-carbo...)
Affinity DataIC50:  85nMAssay Description:Inhibition of sheep COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome c oxidase subunit 1(Ovis aries)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50326828(8-benzoyl-2-(4-(methylsulfonyl)phenyl)quinoline-4-...)
Affinity DataIC50:  1.59E+4nMAssay Description:Inhibition of sheep COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome c oxidase subunit 2(Ovis aries)
Shahid Beheshti University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50326828(8-benzoyl-2-(4-(methylsulfonyl)phenyl)quinoline-4-...)
Affinity DataIC50:  69nMAssay Description:Inhibition of sheep COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome c oxidase subunit 1(Ovis aries)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50326829(6-benzoyl-2-(4-(methylsulfonyl)phenyl)quinoline-4-...)
Affinity DataIC50:  2.44E+4nMAssay Description:Inhibition of sheep COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome c oxidase subunit 2(Ovis aries)
Shahid Beheshti University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50326829(6-benzoyl-2-(4-(methylsulfonyl)phenyl)quinoline-4-...)
Affinity DataIC50:  77nMAssay Description:Inhibition of sheep COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome c oxidase subunit 1(Ovis aries)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50326830(2-(4-azido)phenyl)-8-benzoyl-quinoline-4-carboxyli...)
Affinity DataIC50:  6.56E+4nMAssay Description:Inhibition of sheep COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome c oxidase subunit 2(Ovis aries)
Shahid Beheshti University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50326830(2-(4-azido)phenyl)-8-benzoyl-quinoline-4-carboxyli...)
Affinity DataIC50:  57nMAssay Description:Inhibition of sheep COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome c oxidase subunit 1(Ovis aries)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50326831(2-(4-azido)phenyl)-6-benzoyl-quinoline-4-carboxyli...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of sheep COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome c oxidase subunit 2(Ovis aries)
Shahid Beheshti University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50326831(2-(4-azido)phenyl)-6-benzoyl-quinoline-4-carboxyli...)
Affinity DataIC50:  77nMAssay Description:Inhibition of sheep COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome c oxidase subunit 1(Ovis aries)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50300870(2-(4-(methylsulfonyl)phenyl)-quinoline-4-carboxyli...)
Affinity DataIC50:  1.34E+4nMAssay Description:Inhibition of sheep COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome c oxidase subunit 2(Ovis aries)
Shahid Beheshti University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50300870(2-(4-(methylsulfonyl)phenyl)-quinoline-4-carboxyli...)
Affinity DataIC50:  91nMAssay Description:Inhibition of sheep COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome c oxidase subunit 1(Ovis aries)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  2.43E+4nMAssay Description:Inhibition of sheep COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome c oxidase subunit 2(Ovis aries)
Shahid Beheshti University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  60nMAssay Description:Inhibition of sheep COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome c oxidase subunit 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50343721(3-(4-(4-(2-fluoro-4-methylphenyl)-5-(4-methoxyphen...)
Affinity DataIC50:  130nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome c oxidase subunit 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50343722(3-(4-(5-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-4-(2...)
Affinity DataIC50:  240nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome c oxidase subunit NDUFA4(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50172374(2,2-Dimethyl-6-[1-(3,4,5-trimethoxy-benzyl)-vinyl]...)
Affinity DataIC50:  18nMAssay Description:Inhibitory concentration against NADH ubiquinone oxidoreductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome c oxidase subunit NDUFA4(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50172381(2,2-Dimethyl-2H-chromene-6-carboxylic acid 3,4,5-t...)
Affinity DataIC50:  55nMAssay Description:Inhibitory concentration against NADH ubiquinone oxidoreductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome c oxidase subunit NDUFA4(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50172374(2,2-Dimethyl-6-[1-(3,4,5-trimethoxy-benzyl)-vinyl]...)
Affinity DataIC50:  18nMAssay Description:Inhibitory concentration against NADH-ubiquinone oxidoreductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome c oxidase subunit NDUFA4(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50172381(2,2-Dimethyl-2H-chromene-6-carboxylic acid 3,4,5-t...)
Affinity DataIC50:  55nMAssay Description:Inhibitory concentration against NADH-ubiquinone oxidoreductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome c oxidase subunit 2(Homo sapiens (Human))
Dpsr University

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  540nMAssay Description:Thromboxane (TXA2) receptor antagonist activity using human plateletMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome c oxidase subunit 2(Homo sapiens (Human))
Dpsr University

Curated by ChEMBL
LigandPNGBDBM17636(2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...)
Affinity DataIC50: >1.00E+5nMAssay Description:Thromboxane (TXA2) receptor antagonist activity using human plateletMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome c oxidase subunit 2(Homo sapiens (Human))
Dpsr University

Curated by ChEMBL
LigandPNGBDBM22369(4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofu...)
Affinity DataIC50:  3.00E+3nMAssay Description:Antagonistic activity against TP-receptor by inhibition of U 46619-induced contraction of isolated guinea pig tracheaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome c oxidase subunit 2(Homo sapiens (Human))
Dpsr University

Curated by ChEMBL
LigandPNGBDBM50277998(CHEMBL4174786)
Affinity DataIC50: >1.00E+5nMAssay Description:Antagonistic activity against TP-receptor by inhibition of U 46619-induced contraction of isolated guinea pig tracheaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome c oxidase subunit 2(Homo sapiens (Human))
Dpsr University

Curated by ChEMBL
LigandPNGBDBM50278013(CHEMBL4166887)
Affinity DataIC50: >1.00E+5nMAssay Description:Antagonistic activity against TP-receptor by inhibition of U 46619-induced contraction of isolated guinea pig tracheaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome c oxidase subunit 2(Homo sapiens (Human))
Dpsr University

Curated by ChEMBL
LigandPNGBDBM50277997(CHEMBL4159654)
Affinity DataIC50: >1.00E+5nMAssay Description:Antagonistic activity against TP-receptor by inhibition of U 46619-induced contraction of isolated guinea pig tracheaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome c oxidase subunit 2(Homo sapiens (Human))
Dpsr University

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  610nMAssay Description:Antagonistic activity against TP-receptor by inhibition of U 46619-induced contraction of isolated guinea pig tracheaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome c oxidase subunit 2(Homo sapiens (Human))
Dpsr University

Curated by ChEMBL
LigandPNGBDBM50462392(CHEMBL4248154)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human COX2 assessed as reduction in PGF2alpha production by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome c oxidase subunit 2(Homo sapiens (Human))
Dpsr University

Curated by ChEMBL
LigandPNGBDBM50462395(CHEMBL4238437)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human COX2 assessed as reduction in PGF2alpha production by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome c oxidase subunit 2(Homo sapiens (Human))
Dpsr University

Curated by ChEMBL
LigandPNGBDBM50462397(CHEMBL4245231)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human COX2 assessed as reduction in PGF2alpha production by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome c oxidase subunit 2(Homo sapiens (Human))
Dpsr University

Curated by ChEMBL
LigandPNGBDBM50462396(CHEMBL4238730)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human COX2 assessed as reduction in PGF2alpha production by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome c oxidase subunit 2(Homo sapiens (Human))
Dpsr University

Curated by ChEMBL
LigandPNGBDBM50462393(CHEMBL4249427)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human COX2 assessed as reduction in PGF2alpha production by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome c oxidase subunit 2(Homo sapiens (Human))
Dpsr University

Curated by ChEMBL
LigandPNGBDBM50462394(CHEMBL4249650)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human COX2 assessed as reduction in PGF2alpha production by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome c oxidase subunit 2(Homo sapiens (Human))
Dpsr University

Curated by ChEMBL
LigandPNGBDBM50462391(CHEMBL4238142)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human COX2 assessed as reduction in PGF2alpha production by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome c(Homo sapiens)
Instituto De Qu£Mica Avanzada De Catalu£A

Curated by ChEMBL
LigandPNGBDBM50482423(CHEMBL353314 | Mesotetra(4-Carboxyphenyl)Porphine ...)
Affinity DataKd:  950nMAssay Description:Binding affinity to Cytochrome CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome c(Homo sapiens)
Instituto De Qu£Mica Avanzada De Catalu£A

Curated by ChEMBL
LigandPNGBDBM50482424(CHEMBL1213293)
Affinity DataKd:  1.70E+3nMAssay Description:Binding affinity to Cytochrome CMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome c(Homo sapiens)
Instituto De Qu£Mica Avanzada De Catalu£A

Curated by ChEMBL
LigandPNGBDBM50482425(CHEMBL438407)
Affinity DataKd:  1.70E+4nMAssay Description:Binding affinity to Cytochrome CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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