Found 4282 Enz. Inhib. hit(s) with Target = 'Disintegrin and metalloproteinase domain-containing protein 17'
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataEC50: 1.00E+3nMAssay Description:TNF-α can induce necroptosis in Jurkat cells (human T lymphocytes) when FADD was deleted. This model was used to screen various libraries of che...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataEC50: 1.05E+3nMAssay Description:TNF-α can induce necroptosis in Jurkat cells (human T lymphocytes) when FADD was deleted. This model was used to screen various libraries of che...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataEC50: 1.70E+3nMAssay Description:TNF-α can induce necroptosis in Jurkat cells (human T lymphocytes) when FADD was deleted. This model was used to screen various libraries of che...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataEC50: 2.00E+3nMAssay Description:TNF-α can induce necroptosis in Jurkat cells (human T lymphocytes) when FADD was deleted. This model was used to screen various libraries of che...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataEC50: 2.40E+3nMAssay Description:TNF-α can induce necroptosis in Jurkat cells (human T lymphocytes) when FADD was deleted. This model was used to screen various libraries of che...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataEC50: 2.50E+3nMAssay Description:TNF-α can induce necroptosis in Jurkat cells (human T lymphocytes) when FADD was deleted. This model was used to screen various libraries of che...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataEC50: 3.00E+3nMAssay Description:TNF-α can induce necroptosis in Jurkat cells (human T lymphocytes) when FADD was deleted. This model was used to screen various libraries of che...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataEC50: 3.50E+3nMAssay Description:TNF-α can induce necroptosis in Jurkat cells (human T lymphocytes) when FADD was deleted. This model was used to screen various libraries of che...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataEC50: 5.00E+3nMAssay Description:TNF-α can induce necroptosis in Jurkat cells (human T lymphocytes) when FADD was deleted. This model was used to screen various libraries of che...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataEC50: 7.00E+3nMAssay Description:TNF-α can induce necroptosis in Jurkat cells (human T lymphocytes) when FADD was deleted. This model was used to screen various libraries of che...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
TargetDisintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q](Homo sapiens (Human))
Schering-Plough Research Institute
Schering-Plough Research Institute
Affinity DataKi: 0.0600nM ΔG°: -57.8kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataKi: 0.100nMAssay Description:Inhibition of TACE assessed as inhibition of pro-TNFalpha peptide cleavageMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataKi: 0.140nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
TargetDisintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q](Homo sapiens (Human))
Schering-Plough Research Institute
Schering-Plough Research Institute
Affinity DataKi: 0.140nM ΔG°: -55.7kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataKi: 0.140nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Sus scrofa (pig))
University Of Athens
Curated by ChEMBL
University Of Athens
Curated by ChEMBL
Affinity DataKi: 0.150nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Sus scrofa (pig))
University Of Athens
Curated by ChEMBL
University Of Athens
Curated by ChEMBL
Affinity DataKi: 0.150nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataKi: 0.150nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataKi: 0.150nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
TargetDisintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q](Homo sapiens (Human))
Schering-Plough Research Institute
Schering-Plough Research Institute
Affinity DataKi: 0.180nM ΔG°: -55.1kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataKi: 0.180nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataKi: 0.200nMAssay Description:Inhibition of catalytic domain TACE (unknown origin) by FRET assayMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataKi: 0.200nMAssay Description:Inhibition of catalytic domain TACE (unknown origin) by FRET assayMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataKi: 0.200nMAssay Description:Inhibition of TACE assessed as inhibition of pro-TNFalpha peptide cleavageMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataKi: 0.210nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataKi: 0.25nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataKi: 0.280nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataKi: 0.300nMAssay Description:Inhibition of catalytic domain TACE (unknown origin) by FRET assayMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataKi: 0.300nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Sus scrofa (pig))
University Of Athens
Curated by ChEMBL
University Of Athens
Curated by ChEMBL
Affinity DataKi: 0.350nMAssay Description:Inhibition of porcine TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Sus scrofa (pig))
University Of Athens
Curated by ChEMBL
University Of Athens
Curated by ChEMBL
Affinity DataKi: 0.350nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataKi: 0.360nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataKi: 0.380nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataKi: 0.400nMAssay Description:Inhibition of TACE by FRET assayMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Institut National De La Sante Et De La Recherche Medicale (Inserm)
US Patent
Affinity DataKi: 0.400nMAssay Description:Inhibition of recombinant human TNF-alpha converting enzyme (TACE)More data for this Ligand-Target Pair