Affinity DataEC50: 29nMAssay Description:Inhibition of TEL fused wild type TRKC (unknown origin) transfected in mouse BaF3 cells assessed as reduction in phosphorylation at Y516 residue afte...More data for this Ligand-Target Pair
Affinity DataEC50: 30nMAssay Description:Inhibition of TrkC by cellular assayMore data for this Ligand-Target Pair
Affinity DataEC50: 90nMAssay Description:Agonist activity at TrkC (unknown origin) in expressed in U2OS cells incubated for 3 hrs and measured after 60 hrs in presence of NT-3 by fluorescenc...More data for this Ligand-Target Pair
Affinity DataEC50: 170nMAssay Description:Agonist activity at TrkC (unknown origin) in expressed in U2OS cells incubated for 3 hrs and measured after 60 hrs in presence of NT-3 by fluorescenc...More data for this Ligand-Target Pair
Affinity DataEC50: 180nMAssay Description:Agonist activity at TrkC (unknown origin) in expressed in U2OS cells incubated for 3 hrs and measured after 60 hrs in presence of NT-3 by fluorescenc...More data for this Ligand-Target Pair
Affinity DataEC50: 190nMAssay Description:Agonist activity at TrkC (unknown origin) in expressed in U2OS cells incubated for 3 hrs and measured after 60 hrs in presence of NT-3 by fluorescenc...More data for this Ligand-Target Pair
Affinity DataEC50: 220nMAssay Description:Agonist activity at TrkC (unknown origin) in expressed in U2OS cells incubated for 3 hrs and measured after 60 hrs in presence of NT-3 by fluorescenc...More data for this Ligand-Target Pair
Affinity DataEC50: 330nMAssay Description:Agonist activity at TrkC (unknown origin) in expressed in U2OS cells incubated for 3 hrs and measured after 60 hrs in presence of NT-3 by fluorescenc...More data for this Ligand-Target Pair
Affinity DataEC50: 330nMAssay Description:Agonist activity at TrkC (unknown origin) in expressed in U2OS cells incubated for 3 hrs and measured after 60 hrs in presence of NT-3 by fluorescenc...More data for this Ligand-Target Pair
Affinity DataEC50: 480nMAssay Description:Agonist activity at TrkC (unknown origin) in expressed in U2OS cells incubated for 3 hrs and measured after 60 hrs in presence of NT-3 by fluorescenc...More data for this Ligand-Target Pair
Affinity DataEC50: 510nMAssay Description:Agonist activity at TrkC (unknown origin) in expressed in U2OS cells incubated for 3 hrs and measured after 60 hrs in presence of NT-3 by fluorescenc...More data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+3nMAssay Description:Agonist activity at TrkC (unknown origin) in expressed in U2OS cells incubated for 3 hrs and measured after 60 hrs in presence of NT-3 by fluorescenc...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+3nMAssay Description:Inhibition of TrkC by cellular assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.40E+3nMAssay Description:Agonist activity at TrkC (unknown origin) in expressed in U2OS cells incubated for 3 hrs and measured after 60 hrs in presence of NT-3 by fluorescenc...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Binding affinity to TrkC (unknown origin) assessed as inhibition constant by radiometric assayMore data for this Ligand-Target Pair
Affinity DataKd: 210nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 34nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 190nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 190nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 2.00E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 1.70E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 220nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 600nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 17nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 5.10E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 200nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataIC50: 0.525nMpH: 7.5Assay Description:Compounds to be tested were dissolved in 100% DMSO in a range of concentrations from 10-8 to 10-3 M including negative control (DMSO), then diluted w...More data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMpH: 7.5Assay Description:Compounds to be tested were dissolved in 100% DMSO in a range of concentrations from 10-8 to 10-3 M including negative control (DMSO), then diluted w...More data for this Ligand-Target Pair
Affinity DataIC50: 1.58nMpH: 7.5Assay Description:Compounds to be tested were dissolved in 100% DMSO in a range of concentrations from 10-8 to 10-3 M including negative control (DMSO), then diluted w...More data for this Ligand-Target Pair
Affinity DataIC50: 0.503nMAssay Description:Human TrkC, catalytic domain [456-825(end) amino acids of accession number NP-002521.2] was expressed as N-terminal GST-fusion protein (69 kDa) using...More data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:Inhibition of NRTK3 (unknown origin) by TR-FRET-based Z'-LYTE assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.70E+3nMAssay Description:Binding affinity to TRKCMore data for this Ligand-Target Pair
Affinity DataKd: 14nMAssay Description:Binding affinity to TRKCMore data for this Ligand-Target Pair
Affinity DataKd: 32nMAssay Description:Binding constant for TRKC kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 1.70E+3nMAssay Description:Binding constant for TRKC kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 14nMAssay Description:Binding constant for TRKC kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 17nMAssay Description:Binding constant for TRKC kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 17nMAssay Description:Binding constant for TRKC kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 1.70E+3nMAssay Description:Binding constant for TRKC kinase domainMore data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:Inhibition of TRKC (unknown origin) by Off-chip Mobility Shift AssayMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of Tel-fused TRKC (unknown origin) overexpressed in mouse BA/F3 cells assessed as inhibition of cell proliferation after 48 hrs by lucifer...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of Tel-fused TRKC (unknown origin) overexpressed in mouse BA/F3 cells assessed as inhibition of cell proliferation after 48 hrs by lucifer...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of Tel-fused TRKC (unknown origin) overexpressed in mouse BA/F3 cells assessed as inhibition of cell proliferation after 48 hrs by lucifer...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of Tel-fused TRKC (unknown origin) overexpressed in mouse BA/F3 cells assessed as inhibition of cell proliferation after 48 hrs by lucifer...More data for this Ligand-Target Pair
Affinity DataIC50: 980nMAssay Description:Inhibition of Tel-fused TRKC (unknown origin) overexpressed in mouse BA/F3 cells assessed as inhibition of cell proliferation after 48 hrs by lucifer...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of Tel-fused TRKC (unknown origin) overexpressed in mouse BA/F3 cells assessed as inhibition of cell proliferation after 48 hrs by lucifer...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of Tel-fused TRKC (unknown origin) overexpressed in mouse BA/F3 cells assessed as inhibition of cell proliferation after 48 hrs by lucifer...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of Tel-fused TRKC (unknown origin) overexpressed in mouse BA/F3 cells assessed as inhibition of cell proliferation after 48 hrs by lucifer...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Inhibition of Tel-fused TRKC (unknown origin) overexpressed in mouse BA/F3 cells assessed as inhibition of cell proliferation after 48 hrs by lucifer...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of Tel-fused TRKC (unknown origin) overexpressed in mouse BA/F3 cells assessed as inhibition of cell proliferation after 48 hrs by lucifer...More data for this Ligand-Target Pair