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Found 163 Enz. Inhib. hit(s) with Target = 'Protein arginine N-methyltransferase 3'
TargetProtein arginine N-methyltransferase 3(Homo sapiens)
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50247361(CHEMBL4077534)
Affinity DataEC50:  1.60E+3nMAssay Description:Binding affinity to beta galactosidase fused human PRMT3 (211 to 531 residues) expressed in human A549 cells after 6 hrs by InCELL hunter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3(Homo sapiens)
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50247349(CHEMBL4072005)
Affinity DataEC50:  1.80E+3nMAssay Description:Binding affinity to beta galactosidase fused human PRMT3 (211 to 531 residues) expressed in human HEK293 cells after 6 hrs by InCELL hunter assayMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 3(Homo sapiens)
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50247349(CHEMBL4072005)
Affinity DataEC50:  2.00E+3nMAssay Description:Binding affinity to beta galactosidase fused human PRMT3 (211 to 531 residues) expressed in human A549 cells after 6 hrs by InCELL hunter assayMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 3(Homo sapiens)
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50247361(CHEMBL4077534)
Affinity DataEC50:  2.70E+3nMAssay Description:Binding affinity to beta galactosidase fused human PRMT3 (211 to 531 residues) expressed in human HEK293 cells after 6 hrs by InCELL hunter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3(Homo sapiens)
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50247359(CHEMBL4062783)
Affinity DataEC50:  2.70E+3nMAssay Description:Binding affinity to beta galactosidase fused human PRMT3 (211 to 531 residues) expressed in human A549 cells after 6 hrs by InCELL hunter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3(Homo sapiens)
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50247359(CHEMBL4062783)
Affinity DataEC50:  3.10E+3nMAssay Description:Binding affinity to beta galactosidase fused human PRMT3 (211 to 531 residues) expressed in human HEK293 cells after 6 hrs by InCELL hunter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3(Homo sapiens)
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50247360(CHEMBL4095787)
Affinity DataEC50:  4.90E+3nMAssay Description:Binding affinity to beta galactosidase fused human PRMT3 (211 to 531 residues) expressed in human A549 cells after 6 hrs by InCELL hunter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3(Homo sapiens)
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50247360(CHEMBL4095787)
Affinity DataEC50:  5.20E+3nMAssay Description:Binding affinity to beta galactosidase fused human PRMT3 (211 to 531 residues) expressed in human HEK293 cells after 6 hrs by InCELL hunter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM178103(MS023 (Compound 3) | N1-((4-(4-isopropoxyphenyl)-1...)
Affinity DataKi:  55nM IC50:  119nMAssay Description:In brief, the tritiated S-adenosyl-L-methionine (3HSAM, PerkinElmer Life Sciences) was used as the donor of methyl group. The (3H) methylated biotin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM178102(N1-Methyl-N1-((4-(3-(trifluoromethyl)phenyl)-1H-py...)
Affinity DataKi:  550nM IC50:  1.10E+3nMAssay Description:In brief, the tritiated S-adenosyl-L-methionine (3HSAM, PerkinElmer Life Sciences) was used as the donor of methyl group. The (3H) methylated biotin ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50431676(CHEMBL2349526)
Affinity DataKi:  1.15E+3nMAssay Description:Inhibition of PRMT3 (unknown origin) using [3H]SAM assessed as inhibition of biotinylated-H4 (1 to 24 amino acid residues) methylation after 1 hr by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM178101(N1-Methyl-N1-((5-(3-(trifluoromethyl)phenyl)-2H-1,...)
Affinity DataKi: >5.00E+4nM IC50: >1.00E+5nMAssay Description:In brief, the tritiated S-adenosyl-L-methionine (3HSAM, PerkinElmer Life Sciences) was used as the donor of methyl group. The (3H) methylated biotin ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50: >1.00E+5nMAssay Description:All HMT reactions were performed as described previously [Nasveschuk et al., ACS Med. Chem. Lett., 5:378-383].More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM223137(P5i-6)
Affinity DataIC50: >1.00E+5nMT: 2°CAssay Description:All in vitro enzymatic assays were carried out by Shanghai ChemPartner Co. (998 Halei Road, Pudong New Area, Shanghai, 201203, China). To measure the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50258790((S)-2-amino-N-(3-(5-(5-(benzo[d]thiazol-7-yl)-1,3,...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of PRMT3 by methylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50301077(2-(4-(2-(2,6-dimethoxyphenyl)-7-methyl-1H-benzo[d]...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of PRMT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50328743(3-((4-acetamidophenyl)diazenyl)-4-hydroxy-7-(3-(5-...)
Affinity DataIC50:  7.10E+3nMAssay Description:Inhibition of His6x-tagged PRMT3-mediated arginine methylation expressed in Escherichia coli BL21 (DE3) using GAR R4 peptide and [14C]-SAM by scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50300041(7-(3-(dimethylamino)propoxy)-6-methoxy-2-(4-methyl...)
Affinity DataIC50: >4.00E+4nMAssay Description:Activity at methyl transferase activity PRMT3 by enzyme coupled S-adenocylehomocystein detection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50323813(7-(2-(2-(Dimethylamino)ethoxy)ethoxy)-6-methoxy-2-...)
Affinity DataIC50: >4.00E+4nMAssay Description:Activity at methyl transferase activity PRMT3 by enzyme coupled S-adenocylehomocystein detection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50051117(CHEMBL3318285)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PRMT3 (unknown origin) assessed as incorporation of tritium-labeled methyl group to lysine or arginine residues of peptide substrate by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50427768(CHEMBL2325441)
Affinity DataKd:  9.50E+3nMAssay Description:Binding affinity to 6xHis-tagged recombinant human PRMT3 by surface plasmon resonance analysisMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50427768(CHEMBL2325441)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of recombinant human PRMT3 (211 to 531) using histone-4 (1 to 24) as substrate by S-adenosylhomocysteine hydrolase-coupled assayMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50158087(CHEMBL3781841)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human PRMT3 using 24 residues of biotin labelled histone4 substrate and tritiated 3H-S-adenosylmethionine by scintillation proximity as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50158097(CHEMBL3780701)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of human PRMT3 using 24 residues of biotin labelled histone4 substrate and tritiated 3H-S-adenosylmethionine by scintillation proximity as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50158095(CHEMBL3780444)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibition of human PRMT3 using 24 residues of biotin labelled histone4 substrate and tritiated 3H-S-adenosylmethionine by scintillation proximity as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50158094(CHEMBL3780926)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of human PRMT3 using 24 residues of biotin labelled histone4 substrate and tritiated 3H-S-adenosylmethionine by scintillation proximity as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50353131(CHEMBL1829304)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PRMT3 assessed as hydrolysis of S-adenosyl-L-homocysteine after 2 mins by SAHH-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50431676(CHEMBL2349526)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of PRMT3 (unknown origin) using [3H]SAM assessed as inhibition of biotinylated-H4 (1 to 24 amino acid residues) methylation after 1 hr by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50427752(CHEMBL2325168)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50427753(CHEMBL2325167)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50427754(CHEMBL2325166)
Affinity DataIC50:  7.20E+3nMAssay Description:Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50427755(CHEMBL2325165)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50427756(CHEMBL2325164)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50427757(CHEMBL2325163)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50427758(CHEMBL2325162)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50427759(CHEMBL2325161)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50427760(CHEMBL2325160)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50427761(CHEMBL2325448)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50427762(CHEMBL2325447)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50427763(CHEMBL2325446)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50427764(CHEMBL2325445)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50427765(CHEMBL2325444)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50427766(CHEMBL2325443)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50427767(CHEMBL2325442)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50427768(CHEMBL2325441)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...More data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50427769(CHEMBL2325186)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50427770(CHEMBL2325185)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50427771(CHEMBL2325184)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50427772(CHEMBL2325183)
Affinity DataIC50:  480nMAssay Description:Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...More data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50427773(CHEMBL2325182)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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