Found 84 Enz. Inhib. hit(s) with Target = 'Short transient receptor potential channel 3' TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Affinity DataEC50: 19nMAssay Description:Agonist activity at human TRPC3 expressed in HEK293 cells assessed as induction of membrane depolarization measured for 2.5 mins in presence of 0.5 m...More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Affinity DataEC50: 138nMAssay Description:Agonist activity at human TRPC3 expressed in HEK293 cells assessed as induction of membrane depolarization measured for 2.5 mins in presence of 0.5 m...More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Affinity DataEC50: 236nMAssay Description:Inhibition of rat Angiotensin I converting enzyme (ACE), using Hip-Gly-Gly as synthetic substrate.More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Affinity DataEC50: 450nMAssay Description:Agonist activity at human TRPC3 expressed in HEK293 cells assessed as induction of membrane depolarization measured for 2.5 mins in presence of 0.5 m...More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Affinity DataEC50: <5.01E+4nMAssay Description:Induction of human TRPC3 opening expressed in HEK cells by MSRII FLIPR/summary (Abse5) assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant TRPC3 expressed in HEK293-MSRII cells assessed as carbachol-stimulated Ca2+/Na+ influx after 10 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant TRPC3 expressed in HEK293-MSRII cells assessed as carbachol-stimulated Ca2+/Na+ influx after 10 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Affinity DataIC50: 316nMAssay Description:Inhibition of human recombinant TRPC3 expressed in HEK293-MSRII cells assessed as carbachol-stimulated Ca2+/Na+ influx after 10 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Affinity DataIC50: 316nMAssay Description:Inhibition of human recombinant TRPC3 expressed in HEK293-MSRII cells assessed as carbachol-stimulated Ca2+/Na+ influx after 10 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of human recombinant TRPC3 expressed in HEK293-MSRII cells assessed as carbachol-stimulated Ca2+/Na+ influx after 10 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of human recombinant TRPC3 expressed in HEK293-MSRII cells assessed as carbachol-stimulated Ca2+/Na+ influx after 10 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant TRPC3 expressed in HEK293-MSRII cells assessed as carbachol-stimulated Ca2+/Na+ influx after 10 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant TRPC3 expressed in HEK293-MSRII cells assessed as carbachol-stimulated Ca2+/Na+ influx after 10 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of human recombinant TRPC3 expressed in HEK293-MSRII cells assessed as carbachol-stimulated Ca2+/Na+ influx after 10 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of human recombinant TRPC3 expressed in HEK293-MSRII cells assessed as carbachol-stimulated Ca2+/Na+ influx after 10 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of human recombinant TRPC3 expressed in HEK293-MSRII cells assessed as carbachol-stimulated Ca2+/Na+ influx after 10 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of human recombinant TRPC3 expressed in HEK293-MSRII cells assessed as carbachol-stimulated Ca2+/Na+ influx after 10 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of human recombinant TRPC3 expressed in HEK293-MSRII cells assessed as carbachol-stimulated Ca2+/Na+ influx after 10 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of human recombinant TRPC3 expressed in HEK293-MSRII cells assessed as carbachol-stimulated Ca2+/Na+ influx after 10 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human recombinant TRPC3 expressed in HEK293-MSRII cells assessed as carbachol-stimulated Ca2+/Na+ influx after 10 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of human recombinant TRPC3 expressed in HEK293-MSRII cells assessed as carbachol-stimulated Ca2+/Na+ influx after 10 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of human recombinant TRPC3 expressed in HEK293-MSRII cells assessed as carbachol-stimulated Ca2+/Na+ influx after 10 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of human recombinant TRPC3 expressed in HEK293-MSRII cells assessed as carbachol-stimulated Ca2+/Na+ influx after 10 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of human recombinant TRPC3 expressed in HEK293-MSRII cells assessed as carbachol-stimulated Ca2+/Na+ influx after 10 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human recombinant TRPC3 expressed in HEK293-MSRII cells assessed as carbachol-stimulated Ca2+/Na+ influx after 10 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of human recombinant TRPC3 expressed in HEK293-MSRII cells assessed as carbachol-stimulated Ca2+/Na+ influx after 10 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of human recombinant TRPC3 expressed in HEK293-MSRII cells assessed as carbachol-stimulated Ca2+/Na+ influx after 10 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of human recombinant TRPC3 expressed in HEK293-MSRII cells assessed as carbachol-stimulated Ca2+/Na+ influx after 10 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Affinity DataIC50: 630nMAssay Description:Inhibition of human recombinant TRPC3 expressed in HEK293-MSRII cells assessed as carbachol-stimulated Ca2+/Na+ influx after 10 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Affinity DataIC50: <3.98E+4nMAssay Description:Blocking of human TRPC3 expressed in HEK cells by MSRII FLIPR/summary (Abse5) assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of TRPC3 (unknown origin)More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of TRPC3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Antagonist activity at TRPC3/TRPC6 (unknown origin)More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Affinity DataIC50: 540nMAssay Description:Inhibition of YFP-tagged TRPC3 (unknown origin) expressed in HEK293 cells assessed as reduction carbhocol-induced receptor operated Calcium influx af...More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human TRPC3 expressed in HEK293 cells assessed as reduction in carbachol-induced membrane potential by FMP-2 dye based assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of YFP-tagged human TRPC3 expressed in thapsigargin treated HEK293 cells assessed as reduction in amix-induced calcium level by fluo-4 dye...More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Inhibition of TRPC3 (unknown origin)More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Affinity DataIC50: 4.21E+3nMAssay Description:Inhibition of YFP-tagged TRPC3 (unknown origin) expressed in HEK293 cells assessed as reduction carbhocol-induced receptor operated Calcium influx af...More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Affinity DataIC50: 720nMAssay Description:Inhibition of YFP-tagged TRPC3 (unknown origin) expressed in HEK293 cells assessed as reduction carbhocol-induced receptor operated Calcium influx af...More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Affinity DataIC50: 4.86E+4nMAssay Description:Inhibition of human TRPC3 expressed in HEK293 cells assessed as reduction in carbachol-induced membrane potential by FMP-2 dye based assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human TRPC3 expressed in HEK293 cells assessed as reduction in carbachol-induced membrane potential by FMP-2 dye based assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human TRPC3 expressed in HEK293 cells assessed as reduction in carbachol-induced membrane potential by FMP-2 dye based assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human TRPC3 expressed in HEK293 cells assessed as reduction in carbachol-induced membrane potential by FMP-2 dye based assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Affinity DataIC50: 1.93E+4nMAssay Description:Inhibition of human TRPC3 expressed in HEK293 cells assessed as reduction in carbachol-induced membrane potential by FMP-2 dye based assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Affinity DataIC50: 3.04E+4nMAssay Description:Inhibition of human TRPC3 expressed in HEK293 cells assessed as reduction in carbachol-induced membrane potential by FMP-2 dye based assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Affinity DataIC50: 1.85E+4nMAssay Description:Inhibition of YFP-tagged TRPC3 (unknown origin) expressed in HEK293 cells assessed as reduction carbhocol-induced receptor operated Calcium influx af...More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Affinity DataIC50: 282nMAssay Description:Inhibition of human TRPC3 expressed in CHO cells assessed as reduction in OAG-induced calcium influx after 10 mins by fluo-4/AM dye based FLIPR assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Affinity DataIC50: 370nMAssay Description:Inhibition of human TRPC3 expressed in HEK293 cells assessed as inhibition of GSK170-induced current in absence of extracellular calcium by whole cel...More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Affinity DataIC50: 530nMAssay Description:Inhibition of human TRPC3 expressed in HEK293 cells assessed as inhibition of GSK170-induced current in absence of extracellular calcium by whole cel...More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Moe) And Hubei Provinc
Curated by ChEMBL
Affinity DataIC50: 430nMAssay Description:Inhibition of human TRPC3 expressed in HEK293 cells assessed as inhibition of GSK170-induced current in presence of 2 mM extracellular calcium by who...More data for this Ligand-Target Pair
