TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Tohoku University
Curated by ChEMBL
Tohoku University
Curated by ChEMBL
Affinity DataEC50: 1.90nMAssay Description:Inhibition of NaV1.5 (unknown origin)More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Tohoku University
Curated by ChEMBL
Tohoku University
Curated by ChEMBL
Affinity DataEC50: 28nMAssay Description:Modulator activity at human Nav1.5 expressed in Xenopus laevis oocytes assessed as elicitation in sodium current measured after 1 to 4 days by two-el...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Tohoku University
Curated by ChEMBL
Tohoku University
Curated by ChEMBL
Affinity DataEC50: 108nMAssay Description:Modulator activity at human Nav1.5 expressed in Xenopus laevis oocytes assessed as elicitation in sodium current measured after 1 to 4 days by two-el...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Tohoku University
Curated by ChEMBL
Tohoku University
Curated by ChEMBL
Affinity DataEC50: 133nMAssay Description:Modulator activity at human Nav1.5 expressed in Xenopus laevis oocytes assessed as elicitation in sodium current measured after 1 to 4 days by two-el...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Tohoku University
Curated by ChEMBL
Tohoku University
Curated by ChEMBL
Affinity DataEC50: 138nMAssay Description:Modulator activity at human Nav1.5 expressed in Xenopus laevis oocytes assessed as elicitation in sodium current measured after 1 to 4 days by two-el...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Tohoku University
Curated by ChEMBL
Tohoku University
Curated by ChEMBL
Affinity DataEC50: 149nMAssay Description:Modulator activity at human Nav1.5 expressed in Xenopus laevis oocytes assessed as elicitation in sodium current measured after 1 to 4 days by two-el...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Tohoku University
Curated by ChEMBL
Tohoku University
Curated by ChEMBL
Affinity DataEC50: 156nMAssay Description:Modulator activity at human Nav1.5 expressed in Xenopus laevis oocytes assessed as elicitation in sodium current measured after 1 to 4 days by two-el...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Tohoku University
Curated by ChEMBL
Tohoku University
Curated by ChEMBL
Affinity DataEC50: 215nMAssay Description:Modulator activity at human Nav1.5 expressed in Xenopus laevis oocytes assessed as elicitation in sodium current measured after 1 to 4 days by two-el...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Tohoku University
Curated by ChEMBL
Tohoku University
Curated by ChEMBL
Affinity DataEC50: 5.80E+3nMpH: 7.35 T: 2°CAssay Description:All experiments were conducted at room temperature (22-24° C.) with an EPC-10 amplifier and Pulse software (HEKA, Lambrecht/Pfalz, Germany) in the wh...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Tohoku University
Curated by ChEMBL
Tohoku University
Curated by ChEMBL
Affinity DataEC50: >3.30E+4nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells by IonWorks patch clamp electrophysiology assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Tohoku University
Curated by ChEMBL
Tohoku University
Curated by ChEMBL
Affinity DataKi: 370nMAssay Description:Displacement of [3H]BNZA from Nav1.5 (unknown origin)More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Tohoku University
Curated by ChEMBL
Tohoku University
Curated by ChEMBL
Affinity DataKi: 2.02E+3nMAssay Description:Displacement of [3H]BNZA from Nav1.5 (unknown origin)More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Tohoku University
Curated by ChEMBL
Tohoku University
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:293 cells stably transfected with human Navl .7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology syste...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Tohoku University
Curated by ChEMBL
Tohoku University
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMT: 2°CAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and all...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Tohoku University
Curated by ChEMBL
Tohoku University
Curated by ChEMBL
Affinity DataIC50: 1.07E+3nMT: 2°CAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and all...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Tohoku University
Curated by ChEMBL
Tohoku University
Curated by ChEMBL
Affinity DataIC50: 772nMT: 2°CAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and all...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Tohoku University
Curated by ChEMBL
Tohoku University
Curated by ChEMBL
Affinity DataIC50: 2.58E+3nMT: 2°CAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and all...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Tohoku University
Curated by ChEMBL
Tohoku University
Curated by ChEMBL
Affinity DataIC50: 60.6nMT: 2°CAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and all...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Tohoku University
Curated by ChEMBL
Tohoku University
Curated by ChEMBL
Affinity DataIC50: 101nMT: 2°CAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and all...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Tohoku University
Curated by ChEMBL
Tohoku University
Curated by ChEMBL
Affinity DataIC50: 653nMT: 2°CAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and all...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Tohoku University
Curated by ChEMBL
Tohoku University
Curated by ChEMBL
Affinity DataIC50: 159nMT: 2°CAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and all...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Tohoku University
Curated by ChEMBL
Tohoku University
Curated by ChEMBL
Affinity DataIC50: 1.95E+3nMT: 2°CAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and all...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Tohoku University
Curated by ChEMBL
Tohoku University
Curated by ChEMBL
Affinity DataIC50: 51.5nMT: 2°CAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and all...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Tohoku University
Curated by ChEMBL
Tohoku University
Curated by ChEMBL
Affinity DataIC50: 700nMT: 2°CAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and all...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Tohoku University
Curated by ChEMBL
Tohoku University
Curated by ChEMBL
Affinity DataIC50: 3.76E+3nMT: 2°CAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and all...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Tohoku University
Curated by ChEMBL
Tohoku University
Curated by ChEMBL
Affinity DataIC50: 7.82E+3nMT: 2°CAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and all...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Tohoku University
Curated by ChEMBL
Tohoku University
Curated by ChEMBL
Affinity DataIC50: 743nMT: 2°CAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and all...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Tohoku University
Curated by ChEMBL
Tohoku University
Curated by ChEMBL
Affinity DataIC50: 427nMT: 2°CAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and all...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Tohoku University
Curated by ChEMBL
Tohoku University
Curated by ChEMBL
Affinity DataIC50: 110nMT: 2°CAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and all...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Tohoku University
Curated by ChEMBL
Tohoku University
Curated by ChEMBL
Affinity DataIC50: 26nMT: 2°CAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and all...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Tohoku University
Curated by ChEMBL
Tohoku University
Curated by ChEMBL
Affinity DataIC50: 422nMT: 2°CAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and all...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Tohoku University
Curated by ChEMBL
Tohoku University
Curated by ChEMBL
Affinity DataIC50: 714nMT: 2°CAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and all...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Tohoku University
Curated by ChEMBL
Tohoku University
Curated by ChEMBL
Affinity DataIC50: 14nMT: 2°CAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and all...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Tohoku University
Curated by ChEMBL
Tohoku University
Curated by ChEMBL
Affinity DataIC50: 326nMT: 2°CAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and all...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Tohoku University
Curated by ChEMBL
Tohoku University
Curated by ChEMBL
Affinity DataIC50: 5.23E+3nMT: 2°CAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and all...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Tohoku University
Curated by ChEMBL
Tohoku University
Curated by ChEMBL
Affinity DataIC50: 22nMT: 2°CAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and all...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Tohoku University
Curated by ChEMBL
Tohoku University
Curated by ChEMBL
Affinity DataIC50: 144nMT: 2°CAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and all...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Tohoku University
Curated by ChEMBL
Tohoku University
Curated by ChEMBL
Affinity DataIC50: 670nMT: 2°CAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and all...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Tohoku University
Curated by ChEMBL
Tohoku University
Curated by ChEMBL
Affinity DataIC50: 40nMT: 2°CAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and all...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Tohoku University
Curated by ChEMBL
Tohoku University
Curated by ChEMBL
Affinity DataIC50: 140nMT: 2°CAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and all...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Tohoku University
Curated by ChEMBL
Tohoku University
Curated by ChEMBL
Affinity DataIC50: 130nMT: 2°CAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and all...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Tohoku University
Curated by ChEMBL
Tohoku University
Curated by ChEMBL
Affinity DataIC50: 3.50E+3nMT: 2°CAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and all...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Tohoku University
Curated by ChEMBL
Tohoku University
Curated by ChEMBL
Affinity DataIC50: 630nMT: 2°CAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and all...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Tohoku University
Curated by ChEMBL
Tohoku University
Curated by ChEMBL
Affinity DataIC50: 950nMT: 2°CAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and all...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Tohoku University
Curated by ChEMBL
Tohoku University
Curated by ChEMBL
Affinity DataIC50: 350nMT: 2°CAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and all...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Tohoku University
Curated by ChEMBL
Tohoku University
Curated by ChEMBL
Affinity DataIC50: 430nMT: 2°CAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and all...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Tohoku University
Curated by ChEMBL
Tohoku University
Curated by ChEMBL
Affinity DataIC50: 90nMT: 2°CAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and all...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Tohoku University
Curated by ChEMBL
Tohoku University
Curated by ChEMBL
Affinity DataIC50: 130nMT: 2°CAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and all...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Tohoku University
Curated by ChEMBL
Tohoku University
Curated by ChEMBL
Affinity DataIC50: 160nMT: 2°CAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and all...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Tohoku University
Curated by ChEMBL
Tohoku University
Curated by ChEMBL
Affinity DataIC50: 7.50E+3nMT: 2°CAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and all...More data for this Ligand-Target Pair