Compile Data Set for Download or QSAR
maximum 50k data
Found 33 Enz. Inhib. hit(s) with Target = 'Carbonyl reductase [NADPH] 1'
TargetCarbonyl reductase [NADPH] 1(Homo sapiens (Human))
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50543400(CHEMBL4640248)
Affinity DataIC50:  34nMAssay Description:Inhibition of CBR1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonyl reductase [NADPH] 1(Homo sapiens (Human))
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50543404(CHEMBL4640154)
Affinity DataIC50:  75nMAssay Description:Inhibition of CBR1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonyl reductase [NADPH] 1(Homo sapiens (Human))
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50543405(CHEMBL4639417)
Affinity DataIC50:  120nMAssay Description:Inhibition of CBR1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonyl reductase [NADPH] 1(Homo sapiens (Human))
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50247677((3S,8S)-14,16-dihydroxy-3,8-dimethyl-3,4,5,6,9,10-...)
Affinity DataIC50:  210nMAssay Description:Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as NADPH oxidation using isatin as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonyl reductase [NADPH] 1(Homo sapiens (Human))
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50543397(CHEMBL4646593)
Affinity DataIC50:  250nMAssay Description:Inhibition of CBR1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCarbonyl reductase [NADPH] 1(Homo sapiens (Human))
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50543399(CHEMBL4648793)
Affinity DataIC50:  270nMAssay Description:Inhibition of CBR1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCarbonyl reductase [NADPH] 1(Homo sapiens (Human))
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50543402(CHEMBL4634960)
Affinity DataIC50:  370nMAssay Description:Inhibition of CBR1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonyl reductase [NADPH] 1(Homo sapiens (Human))
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM8726(5-chloro-2-(2,4-dichlorophenoxy)phenol | CHEMBL849...)
Affinity DataIC50:  400nMAssay Description:Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as NADPH oxidation using isatin as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonyl reductase [NADPH] 1(Homo sapiens (Human))
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50543401(CHEMBL4644092)
Affinity DataIC50:  440nMAssay Description:Inhibition of CBR1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonyl reductase [NADPH] 1(Homo sapiens (Human))
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
Affinity DataIC50:  670nMAssay Description:Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as NADPH oxidation using isatin as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonyl reductase [NADPH] 1(Homo sapiens (Human))
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50308752(3-(1-tert-butyl-4-amino-1H-pyrazolo[3,4-d]pyrimidi...)
Affinity DataIC50:  759nMAssay Description:Inhibition of CBR-mediated NADPH-dependent reduction of menadione to menadiolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonyl reductase [NADPH] 1(Homo sapiens (Human))
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50308752(3-(1-tert-butyl-4-amino-1H-pyrazolo[3,4-d]pyrimidi...)
Affinity DataIC50:  788nMAssay Description:Inhibition of CBR-mediated NADPH-dependent reduction of menadione to menadiolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonyl reductase [NADPH] 1(Homo sapiens (Human))
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50241828(CHEMBL4089817)
Affinity DataIC50:  1.10E+3nMAssay Description:Binding affinity against high affinity component of Adenosine A1 receptor from rat brain membranes using [3H]-DPCPXMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonyl reductase [NADPH] 1(Homo sapiens (Human))
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50308753(3-(Methyl-N-ethylcarbamate)-5-hydroxybenz[f]indazo...)
Affinity DataIC50:  3.00E+3nMAssay Description:Displacement of menadione from human recombinant CBR expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonyl reductase [NADPH] 1(Homo sapiens (Human))
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50073099((9E,11E)-(4R,6R,8R)-16-chloro-17,19-dihydroxy-4-me...)
Affinity DataIC50:  3.27E+3nMAssay Description:Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as NADPH oxidation using isatin as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonyl reductase [NADPH] 1(Homo sapiens (Human))
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50096619(1,8,9-Trihydroxy-3-methoxy-benzo[4,5]furo[3,2-c]ch...)
Affinity DataIC50:  3.78E+3nMAssay Description:Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as NADPH oxidation using isatin as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonyl reductase [NADPH] 1(Homo sapiens (Human))
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50308751(3-(methyl-N-ethylcarbamate)-6-(N0-ethylphenylamino...)
Affinity DataIC50:  4.00E+3nMAssay Description:Displacement of menadione from human recombinant CBR expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonyl reductase [NADPH] 1(Homo sapiens (Human))
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50308750(3-(Methyl-N-ethylcarbamate)-6-(N0-methylphenylamin...)
Affinity DataIC50:  4.00E+3nMAssay Description:Displacement of menadione from human recombinant CBR expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonyl reductase [NADPH] 1(Homo sapiens (Human))
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50241817(CHEMBL4081954)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of recombinant human CBR1 using isatin as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonyl reductase [NADPH] 1(Homo sapiens (Human))
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50308754(3-(Methyl-N-ethylcarbamate)-6,7-dichloro-5,8-dimet...)
Affinity DataIC50:  5.00E+3nMAssay Description:Displacement of menadione from human recombinant CBR expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonyl reductase [NADPH] 1(Homo sapiens (Human))
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50308750(3-(Methyl-N-ethylcarbamate)-6-(N0-methylphenylamin...)
Affinity DataIC50:  1.10E+4nMAssay Description:Displacement of daunorubicin from human recombinant CBR expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonyl reductase [NADPH] 1(Homo sapiens (Human))
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM9461(5,7-dihydroxy-3-(4-methoxyphenyl)-4H-chromen-4-one...)
Affinity DataIC50:  1.27E+4nMAssay Description:Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as NADPH oxidation using isatin as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonyl reductase [NADPH] 1(Homo sapiens (Human))
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50308751(3-(methyl-N-ethylcarbamate)-6-(N0-ethylphenylamino...)
Affinity DataIC50:  1.30E+4nMAssay Description:Displacement of daunorubicin from human recombinant CBR expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonyl reductase [NADPH] 1(Homo sapiens (Human))
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50308753(3-(Methyl-N-ethylcarbamate)-5-hydroxybenz[f]indazo...)
Affinity DataIC50:  2.00E+4nMAssay Description:Displacement of daunorubicin from human recombinant CBR expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonyl reductase [NADPH] 1(Homo sapiens (Human))
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM23419((2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro...)
Affinity DataIC50:  2.15E+4nMAssay Description:Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as NADPH oxidation using isatin as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonyl reductase [NADPH] 1(Homo sapiens (Human))
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50308754(3-(Methyl-N-ethylcarbamate)-6,7-dichloro-5,8-dimet...)
Affinity DataIC50:  2.50E+4nMAssay Description:Displacement of daunorubicin from human recombinant CBR expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonyl reductase [NADPH] 1(Homo sapiens (Human))
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50247677((3S,8S)-14,16-dihydroxy-3,8-dimethyl-3,4,5,6,9,10-...)
Affinity DataKi:  40nMAssay Description:Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as NADPH oxidation using isatin as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonyl reductase [NADPH] 1(Homo sapiens (Human))
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM8726(5-chloro-2-(2,4-dichlorophenoxy)phenol | CHEMBL849...)
Affinity DataKi:  60nMAssay Description:Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as NADPH oxidation using isatin as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonyl reductase [NADPH] 1(Homo sapiens (Human))
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
Affinity DataKi:  110nMAssay Description:Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as NADPH oxidation using isatin as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonyl reductase [NADPH] 1(Homo sapiens (Human))
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50073099((9E,11E)-(4R,6R,8R)-16-chloro-17,19-dihydroxy-4-me...)
Affinity DataKi:  520nMAssay Description:Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as NADPH oxidation using isatin as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonyl reductase [NADPH] 1(Homo sapiens (Human))
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50096619(1,8,9-Trihydroxy-3-methoxy-benzo[4,5]furo[3,2-c]ch...)
Affinity DataKi:  600nMAssay Description:Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as NADPH oxidation using isatin as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonyl reductase [NADPH] 1(Homo sapiens (Human))
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM9461(5,7-dihydroxy-3-(4-methoxyphenyl)-4H-chromen-4-one...)
Affinity DataKi:  2.03E+3nMAssay Description:Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as NADPH oxidation using isatin as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonyl reductase [NADPH] 1(Homo sapiens (Human))
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM23419((2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro...)
Affinity DataKi:  3.43E+3nMAssay Description:Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as NADPH oxidation using isatin as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed