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Found 1125 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase Sgk1'
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50382224(CHEMBL2023841)
Affinity DataKd:  28nMAssay Description:Binding affinity to SGK1 by fluorescence anisotropy assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50505541(CHEMBL4465866)
Affinity DataKd:  331nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged SGK1 (unknown origin) (60 to 431 residues) expressed in baculovirus infect...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50505542(CHEMBL4576489)
Affinity DataKd:  566nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged SGK1 (unknown origin) (60 to 431 residues) expressed in baculovirus infect...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50402020(CHEMBL2205426)
Affinity DataKi:  260nMAssay Description:Inhibition of recombinant SGK after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM7393(3-[(2Z,3E)-3-(hydroxyimino)-2,3-dihydro-1H-indol-2...)
Affinity DataKi:  380nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50540597(CHEMBL4638374)
Affinity DataKi:  600nMAssay Description:Inhibition of human N-terminal His6-tagged N-truncated human SGK1 harboring S422D mutant expressed in Sf21 cells using Sgktide-peptide as substrate i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50341519((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of SGK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50463479(CHEMBL4249925)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of SGK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50463483(CHEMBL4245242)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of SGK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50463484(CHEMBL4248525)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of SGK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50463479(CHEMBL4249925)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of SGK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50224883(7-chloro-3-oxo-8-[(thiazol-5-ylmethyl)-amino]-11,1...)
Affinity DataKi:  8.18E+3nMAssay Description:Inhibition of SGKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM93227(Kinase inhibitor, C2)
Affinity DataIC50:  1.10E+5nMAssay Description:Selected compounds were screened against a panel of mammalian kinases. Compounds were supplied in DMSO and screened in duplicates at 100 uM concentr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50443636(CHEMBL3092460 | US9174993, 1 | US9221828, 1)
Affinity DataIC50:  3nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50043786(CHEMBL3356055 | US9174993, 2 | US9221828, 2)
Affinity DataIC50:  439nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50043787(CHEMBL3356056 | US9174993, 3 | US9221828, 3)
Affinity DataIC50:  496nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50043871(CHEMBL3356057 | US9174993, 4 | US9221828, 4)
Affinity DataIC50:  419nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50443635(CHEMBL3092461 | US9174993, 5 | US9221828, 5)
Affinity DataIC50:  5nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50443634(CHEMBL3092462 | US9174993, 6 | US9221828, 6)
Affinity DataIC50:  2nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50443633(CHEMBL3092463 | US9174993, 7 | US9221828, 7)
Affinity DataIC50:  2nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50043899(CHEMBL3356040 | US9174993, 8 | US9221828, 8)
Affinity DataIC50:  196nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50043784(CHEMBL3356054 | US9174993, 9 | US9221828, 9)
Affinity DataIC50:  3nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50043872(CHEMBL3356058 | US9174993, 10 | US9221828, 10)
Affinity DataIC50:  13nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50043873(CHEMBL3356059 | US9174993, 11 | US9221828, 11)
Affinity DataIC50:  2nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50443632(CHEMBL3092464 | US9174993, 12 | US9221828, 12)
Affinity DataIC50:  4nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50043874(CHEMBL3356060 | US9174993, 13 | US9221828, 13)
Affinity DataIC50:  3nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50443631(CHEMBL3092465 | US9174993, 14 | US9221828, 14)
Affinity DataIC50:  3nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50443630(CHEMBL3092466 | US9174993, 15 | US9221828, 15)
Affinity DataIC50:  2nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50443629(CHEMBL3092467 | US9174993, 16 | US9221828, 16)
Affinity DataIC50:  2nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50443628(CHEMBL3092468 | US9174993, 35 | US9221828, 35)
Affinity DataIC50:  1nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM189805(US9174993, 42 | US9221828, 42)
Affinity DataIC50:  413nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM189806(US9174993, 43)
Affinity DataIC50:  1.05E+3nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM189807(US9174993, 45 | US9221828, 45)
Affinity DataIC50:  47nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50043783(CHEMBL3356053 | US9174993, 46 | US9221828, 46)
Affinity DataIC50:  2nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50043921(CHEMBL3356047 | US9174993, 58)
Affinity DataIC50:  15nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50043920(CHEMBL3356046 | US9174993, 59)
Affinity DataIC50:  22nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM189808(US9174993, 60)
Affinity DataIC50:  31nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM189809(US9174993, 61)
Affinity DataIC50:  18nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50043917(CHEMBL3356042 | US9174993, 63)
Affinity DataIC50:  21nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50043916(CHEMBL3356041 | US9174993, 64)
Affinity DataIC50:  14nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50443636(CHEMBL3092460 | US9174993, 1 | US9221828, 1)
Affinity DataIC50:  3nMpH: 7.4 T: 2°CAssay Description:The enzyme reaction was carried out in a buffer containing 25 mM Tris-HCl (pH 7.4), 5 mM MgCl2, 2 mM MnCl2, 2 mM DTT, and 0.03% bovine serum albumi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50043786(CHEMBL3356055 | US9174993, 2 | US9221828, 2)
Affinity DataIC50:  439nMpH: 7.4 T: 2°CAssay Description:The enzyme reaction was carried out in a buffer containing 25 mM Tris-HCl (pH 7.4), 5 mM MgCl2, 2 mM MnCl2, 2 mM DTT, and 0.03% bovine serum albumi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50043787(CHEMBL3356056 | US9174993, 3 | US9221828, 3)
Affinity DataIC50:  496nMpH: 7.4 T: 2°CAssay Description:The enzyme reaction was carried out in a buffer containing 25 mM Tris-HCl (pH 7.4), 5 mM MgCl2, 2 mM MnCl2, 2 mM DTT, and 0.03% bovine serum albumi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50043871(CHEMBL3356057 | US9174993, 4 | US9221828, 4)
Affinity DataIC50:  419nMpH: 7.4 T: 2°CAssay Description:The enzyme reaction was carried out in a buffer containing 25 mM Tris-HCl (pH 7.4), 5 mM MgCl2, 2 mM MnCl2, 2 mM DTT, and 0.03% bovine serum albumi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50443635(CHEMBL3092461 | US9174993, 5 | US9221828, 5)
Affinity DataIC50:  5nMpH: 7.4 T: 2°CAssay Description:The enzyme reaction was carried out in a buffer containing 25 mM Tris-HCl (pH 7.4), 5 mM MgCl2, 2 mM MnCl2, 2 mM DTT, and 0.03% bovine serum albumi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50443634(CHEMBL3092462 | US9174993, 6 | US9221828, 6)
Affinity DataIC50:  2nMpH: 7.4 T: 2°CAssay Description:The enzyme reaction was carried out in a buffer containing 25 mM Tris-HCl (pH 7.4), 5 mM MgCl2, 2 mM MnCl2, 2 mM DTT, and 0.03% bovine serum albumi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50443633(CHEMBL3092463 | US9174993, 7 | US9221828, 7)
Affinity DataIC50:  2nMpH: 7.4 T: 2°CAssay Description:The enzyme reaction was carried out in a buffer containing 25 mM Tris-HCl (pH 7.4), 5 mM MgCl2, 2 mM MnCl2, 2 mM DTT, and 0.03% bovine serum albumi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50043899(CHEMBL3356040 | US9174993, 8 | US9221828, 8)
Affinity DataIC50:  196nMpH: 7.4 T: 2°CAssay Description:The enzyme reaction was carried out in a buffer containing 25 mM Tris-HCl (pH 7.4), 5 mM MgCl2, 2 mM MnCl2, 2 mM DTT, and 0.03% bovine serum albumi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50043784(CHEMBL3356054 | US9174993, 9 | US9221828, 9)
Affinity DataIC50:  3nMpH: 7.4 T: 2°CAssay Description:The enzyme reaction was carried out in a buffer containing 25 mM Tris-HCl (pH 7.4), 5 mM MgCl2, 2 mM MnCl2, 2 mM DTT, and 0.03% bovine serum albumi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50043872(CHEMBL3356058 | US9174993, 10 | US9221828, 10)
Affinity DataIC50:  13nMpH: 7.4 T: 2°CAssay Description:The enzyme reaction was carried out in a buffer containing 25 mM Tris-HCl (pH 7.4), 5 mM MgCl2, 2 mM MnCl2, 2 mM DTT, and 0.03% bovine serum albumi...More data for this Ligand-Target Pair
In DepthDetails US Patent
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