Affinity DataKi: 30nM ΔG°: -44.7kJ/mole IC50: 150nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
Affinity DataIC50: 500nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
Affinity DataIC50: 750nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+4nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
Affinity DataIC50: 4.40E+3nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+4nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+4nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
Affinity DataIC50: 3.60E+3nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
Affinity DataIC50: 4.50E+3nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
Affinity DataIC50: 4.70E+3nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
Affinity DataIC50: 5.20E+3nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
Affinity DataIC50: 1.65E+4nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
Affinity DataIC50: 770nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
Affinity DataIC50: 7.10E+3nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
Affinity DataIC50: 350nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
Affinity DataIC50: 8.20E+3nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
Affinity DataIC50: 5.70E+3nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+3nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
Affinity DataIC50: 550nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
Affinity DataIC50: 410nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+4nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
Affinity DataKi: 5nM IC50: 13nMAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Competitive inhibition of human recombinant mitochondrial thymidine kinase 2 using ATP as substrate by Lineweaver-Burk plottingMore data for this Ligand-Target Pair
TargetThymidine kinase, cytosolic(Homo sapiens (Human))
University Of Massachusetts Medical School
Curated by ChEMBL
University Of Massachusetts Medical School
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Binding affinity of the compound towards HSV-1 thymidine kinase was determinedMore data for this Ligand-Target Pair
TargetThymidine kinase, cytosolic(Homo sapiens (Human))
University Of Massachusetts Medical School
Curated by ChEMBL
University Of Massachusetts Medical School
Curated by ChEMBL
Affinity DataKi: 90nMAssay Description:Binding affinity constant against HSV-1 thymidine kinaseMore data for this Ligand-Target Pair
TargetThymidine kinase, cytosolic(Homo sapiens (Human))
University Of Massachusetts Medical School
Curated by ChEMBL
University Of Massachusetts Medical School
Curated by ChEMBL
Affinity DataKi: 90nMAssay Description:Compound was evaluated for Kinetic constant for viral thymidine kinase of Herpes simplex virus (HSV) -1More data for this Ligand-Target Pair
TargetThymidine kinase, cytosolic(Homo sapiens (Human))
University Of Massachusetts Medical School
Curated by ChEMBL
University Of Massachusetts Medical School
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Binding affinity constant against HSV-1 thymidine kinaseMore data for this Ligand-Target Pair
TargetThymidine kinase, cytosolic(Homo sapiens (Human))
University Of Massachusetts Medical School
Curated by ChEMBL
University Of Massachusetts Medical School
Curated by ChEMBL
Affinity DataKi: 140nMAssay Description:Compound was evaluated for Kinetic constant for viral thymidine kinase of Herpes simplex virus (HSV) -2More data for this Ligand-Target Pair
Affinity DataKi: 150nMAssay Description:Inhibition of thymidine kinase 2More data for this Ligand-Target Pair
TargetThymidine kinase, cytosolic(Homo sapiens (Human))
University Of Massachusetts Medical School
Curated by ChEMBL
University Of Massachusetts Medical School
Curated by ChEMBL
Affinity DataKi: 180nMAssay Description:Compound was evaluated for Kinetic constant for viral thymidine kinase of Herpes simplex virus (HSV) -1More data for this Ligand-Target Pair
TargetThymidine kinase, cytosolic(Homo sapiens (Human))
University Of Massachusetts Medical School
Curated by ChEMBL
University Of Massachusetts Medical School
Curated by ChEMBL
Affinity DataKi: 200nMAssay Description:Binding affinity constant against HSV-1 thymidine kinaseMore data for this Ligand-Target Pair
TargetThymidine kinase, cytosolic(Homo sapiens (Human))
University Of Massachusetts Medical School
Curated by ChEMBL
University Of Massachusetts Medical School
Curated by ChEMBL
Affinity DataKi: 210nMAssay Description:Binding affinity constant against HSV-1 thymidine kinaseMore data for this Ligand-Target Pair
TargetThymidine kinase, cytosolic(Homo sapiens (Human))
University Of Massachusetts Medical School
Curated by ChEMBL
University Of Massachusetts Medical School
Curated by ChEMBL
Affinity DataKi: 220nMAssay Description:Binding affinity constant against HSV-1 thymidine kinaseMore data for this Ligand-Target Pair
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Glsynthesis
Curated by ChEMBL
Glsynthesis
Curated by ChEMBL
Affinity DataKi: 240nMAssay Description:Inhibition of Herpes simplex virus 1 recombinant thymidine kinaseMore data for this Ligand-Target Pair
TargetThymidine kinase(Human herpesvirus 1)
University Of Massachusetts Medical School
Curated by ChEMBL
University Of Massachusetts Medical School
Curated by ChEMBL
Affinity DataKi: 300nMAssay Description:Inhibition of TdR phosphorylation using thymidine kinase assay for herpes simplex virus type 2More data for this Ligand-Target Pair
Affinity DataKi: 410nMAssay Description:Uncompetitive inhibition of human recombinant mitochondrial thymidine kinase 2 using thymidine as substrate by Lineweaver-Burk plottingMore data for this Ligand-Target Pair
TargetThymidine kinase, cytosolic(Homo sapiens (Human))
University Of Massachusetts Medical School
Curated by ChEMBL
University Of Massachusetts Medical School
Curated by ChEMBL
Affinity DataKi: 440nMAssay Description:Compound was evaluated for Kinetic constant for viral thymidine kinase of Herpes simplex virus (HSV) -2More data for this Ligand-Target Pair
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
University Of Massachusetts Medical School
Curated by ChEMBL
University Of Massachusetts Medical School
Curated by ChEMBL
Affinity DataKi: 700nMAssay Description:Inhibition of TdR phosphorylation using thymidine kinase assay for herpes simplex virus type 2More data for this Ligand-Target Pair
TargetThymidine kinase, cytosolic(Homo sapiens (Human))
University Of Massachusetts Medical School
Curated by ChEMBL
University Of Massachusetts Medical School
Curated by ChEMBL
Affinity DataKi: 950nMAssay Description:Compound was evaluated for Kinetic constant for viral thymidine kinase of Herpes simplex virus (HSV) -2More data for this Ligand-Target Pair
TargetThymidine kinase, cytosolic(Homo sapiens (Human))
University Of Massachusetts Medical School
Curated by ChEMBL
University Of Massachusetts Medical School
Curated by ChEMBL
Affinity DataKi: 1.40E+3nMAssay Description:Compound was evaluated for Kinetic constant for viral thymidine kinase of Herpes simplex virus (HSV) -1More data for this Ligand-Target Pair