TargetTumor necrosis factor(Homo sapiens (Human))
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
Affinity DataKd: 5.36E+3nMpH: 6.5Assay Description:Binding affinity to GST-tagged human TNF-alpha in 10 mM citrate-phosphate at pH 6.5 by fluorescence assayMore data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
Affinity DataKd: 110nMpH: 7.0Assay Description:Surface plasmon resonance (SPR) assays were carried out on a BIAcore 3000 instrument (Biacore, Inc). Briefly, purified hTNFα was dissolved at 32...More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
Affinity DataKd: 9.00E+3nMpH: 7.0Assay Description:Surface plasmon resonance (SPR) assays were carried out on a BIAcore 3000 instrument (Biacore, Inc). Briefly, purified hTNFα was dissolved at 32...More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
Affinity DataKi: 0.0300nM IC50: 260nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
Affinity DataKi: 0.0300nM IC50: 383nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
Affinity DataKi: 0.0521nM IC50: 723nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
Affinity DataKi: 0.0524nM IC50: 61nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
Affinity DataKi: 0.0556nM IC50: 65nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
Affinity DataKi: 0.0600nM IC50: 678nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
Affinity DataKi: 0.0627nM IC50: 75.4nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
Affinity DataKi: 0.0630nM IC50: 151nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
Affinity DataKi: 0.0651nM IC50: 80.3nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
Affinity DataKi: 0.0720nM IC50: 92nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
Affinity DataKi: 0.0740nM IC50: 117nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
Affinity DataKi: 0.0762nM IC50: 342nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
Affinity DataKi: 0.0770nM IC50: 119nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
Affinity DataKi: 0.0781nM IC50: 106nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
Affinity DataKi: 0.0826nM IC50: 124nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
Affinity DataKi: 0.0830nM IC50: 65nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
Affinity DataKi: 0.0930nM IC50: 74nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
Affinity DataKi: 0.0930nM IC50: 72.4nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
Affinity DataKi: 0.0973nM IC50: 87nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
Affinity DataKi: 0.0988nM IC50: 39.8nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
Affinity DataKi: 0.100nM IC50: 490nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
Affinity DataKi: 0.110nM IC50: 76nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
Affinity DataKi: 0.110nM IC50: 134nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
Affinity DataKi: 0.110nM IC50: 936nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
Affinity DataKi: 0.115nM IC50: 55.9nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
Affinity DataKi: 0.120nM IC50: 154nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
Affinity DataKi: 0.120nM IC50: 220nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
Affinity DataKi: 0.120nM IC50: 927nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
Affinity DataKi: 0.120nM IC50: 127nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
Affinity DataKi: 0.130nM IC50: 100nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
Affinity DataKi: 0.130nM IC50: 113nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
Affinity DataKi: 0.150nM IC50: 278nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
Affinity DataKi: 0.150nM IC50: 417nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
Affinity DataKi: 0.150nM IC50: 811nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
Affinity DataKi: 0.160nM IC50: 258nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
Affinity DataKi: 0.160nM IC50: 20nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
Affinity DataKi: 0.160nM IC50: 153nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
Affinity DataKi: 0.160nM IC50: 229nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
Affinity DataKi: 0.170nM IC50: 382nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
Affinity DataKi: 0.170nM IC50: 86nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
Affinity DataKi: 0.170nM IC50: 188nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
Affinity DataKi: 0.170nM IC50: 78nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
Affinity DataKi: 0.180nM IC50: 292nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
Affinity DataKi: 0.180nM IC50: 274nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
Affinity DataKi: 0.180nM IC50: 87nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
Affinity DataKi: 0.180nM IC50: 69nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
The Centre For Research And Technology Of Thessaly (Ce.Re.Te.Th.)
Curated by ChEMBL
Affinity DataKi: 0.180nM IC50: 86nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair