Found 646 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase TXK' 
Affinity DataIC50: 194nMpH: 7.4 T: 2°CAssay Description:Test compounds were solubilized in dimethyl sulfoxide (DMSO) to a stock concentration of 30 mM. Compounds were diluted in DMSO to create an 11-point ...More data for this Ligand-Target Pair
Affinity DataKi: 0.131nMpH: 7.5Assay Description:Assay buffer was 20 mM HEPES, pH 7.5, 10 mM MgCl2, 0.01% BSA, 1 mM DTT, 0.0005% Tween 20, and 2% DMSO. Inactivation kinetic reactions were performed ...More data for this Ligand-Target Pair
Affinity DataKi: 131nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged TXK using GEPLYWSFPAKKK as substrate measured every 60 secs for 1 hr by PK/LDH coupled spectrop...More data for this Ligand-Target Pair
Affinity DataKd: 2.10nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 5.50E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 2.60E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 6.00E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 4.50E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 230nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 2.70E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 3.70E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Inhibition of TXK (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of Rlk (unknown origin) after 1 hr by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of Rlk (unknown origin) after 1 hr by HTRF assayMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to TXKMore data for this Ligand-Target Pair
Affinity DataKd: 660nMAssay Description:Binding affinity to TXKMore data for this Ligand-Target Pair
Affinity DataKd: 230nMAssay Description:Binding constant for TXK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for TXK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 860nMAssay Description:Binding constant for TXK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 660nMAssay Description:Binding constant for TXK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for TXK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 230nMAssay Description:Binding constant for TXK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 410nMAssay Description:Binding affinity against delta opioid receptor in mouse hot plate testMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of TxkMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibition of TXK (unknown origin) by Z'-Lyte assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of TXKMore data for this Ligand-Target Pair
Affinity DataIC50: 119nMAssay Description:Inhibition of TXK (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 172nMAssay Description:Inhibition of TXK (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 95nMAssay Description:Inhibition of TXK (unknown origin)More data for this Ligand-Target Pair
Affinity DataKd: 10nMAssay Description:Binding affinity to human TXKMore data for this Ligand-Target Pair
Affinity DataKd: 395nMAssay Description:Binding affinity to human TXKMore data for this Ligand-Target Pair
Affinity DataKd: 80nMAssay Description:Binding affinity to human TXKMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human TXK using [EAIYAAPFAKKK] as substrateMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to TXKMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to TXKMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to TXKMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to TXKMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to TXKMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for TXK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for TXK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for TXK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for TXK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for TXK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 2.60E+3nMAssay Description:Binding constant for TXK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 3.80E+3nMAssay Description:Binding constant for TXK kinase domainMore data for this Ligand-Target Pair
