TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Burnham Institute For Medical Research
Burnham Institute For Medical Research
Affinity DataIC50: 5.37E+3nMpH: 6.0 T: 2°CAssay Description:The phosphatase-catalyzed hydrolysis of 6,8-difluoro-4-methylumbelliferyl phosphate was assayed in the presence of each test compound. The fluorescen...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Burnham Institute For Medical Research
Burnham Institute For Medical Research
Affinity DataIC50: 1.02E+4nMpH: 6.0 T: 2°CAssay Description:The phosphatase-catalyzed hydrolysis of 6,8-difluoro-4-methylumbelliferyl phosphate was assayed in the presence of each test compound. The fluorescen...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Burnham Institute For Medical Research
Burnham Institute For Medical Research
Affinity DataIC50: 2.27E+3nMpH: 6.0 T: 2°CAssay Description:The phosphatase-catalyzed hydrolysis of 6,8-difluoro-4-methylumbelliferyl phosphate was assayed in the presence of each test compound. The fluorescen...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Burnham Institute For Medical Research
Burnham Institute For Medical Research
Affinity DataIC50: 6.40E+3nMpH: 6.0 T: 2°CAssay Description:The phosphatase-catalyzed hydrolysis of 6,8-difluoro-4-methylumbelliferyl phosphate was assayed in the presence of each test compound. The fluorescen...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Burnham Institute For Medical Research
Burnham Institute For Medical Research
Affinity DataIC50: 2.10E+3nMpH: 6.0 T: 2°CAssay Description:The phosphatase-catalyzed hydrolysis of 6,8-difluoro-4-methylumbelliferyl phosphate was assayed in the presence of each test compound. The fluorescen...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Burnham Institute For Medical Research
Burnham Institute For Medical Research
Affinity DataIC50: 3.91E+3nMpH: 6.0 T: 2°CAssay Description:The phosphatase-catalyzed hydrolysis of 6,8-difluoro-4-methylumbelliferyl phosphate was assayed in the presence of each test compound. The fluorescen...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Burnham Institute For Medical Research
Burnham Institute For Medical Research
Affinity DataIC50: 1.83E+3nMpH: 6.0 T: 2°CAssay Description:The phosphatase-catalyzed hydrolysis of 6,8-difluoro-4-methylumbelliferyl phosphate was assayed in the presence of each test compound. The fluorescen...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Burnham Institute For Medical Research
Burnham Institute For Medical Research
Affinity DataIC50: 2.11E+3nMpH: 6.0 T: 2°CAssay Description:The phosphatase-catalyzed hydrolysis of 6,8-difluoro-4-methylumbelliferyl phosphate was assayed in the presence of each test compound. The fluorescen...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Burnham Institute For Medical Research
Burnham Institute For Medical Research
Affinity DataIC50: 5.00E+5nMpH: 6.0 T: 2°CAssay Description:The phosphatase-catalyzed hydrolysis of 6,8-difluoro-4-methylumbelliferyl phosphate was assayed in the presence of each test compound. The fluorescen...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Burnham Institute For Medical Research
Burnham Institute For Medical Research
Affinity DataIC50: 450nMpH: 6.0 T: 2°CAssay Description:The phosphatase-catalyzed hydrolysis of 6,8-difluoro-4-methylumbelliferyl phosphate was assayed in the presence of each test compound. The fluorescen...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Burnham Institute For Medical Research
Burnham Institute For Medical Research
Affinity DataIC50: 1.99E+4nMpH: 6.0 T: 2°CAssay Description:The phosphatase-catalyzed hydrolysis of 6,8-difluoro-4-methylumbelliferyl phosphate was assayed in the presence of each test compound. The fluorescen...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Burnham Institute For Medical Research
Burnham Institute For Medical Research
Affinity DataIC50: 4.55E+3nMpH: 6.0 T: 2°CAssay Description:The phosphatase-catalyzed hydrolysis of 6,8-difluoro-4-methylumbelliferyl phosphate was assayed in the presence of each test compound. The fluorescen...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataIC50: >8.00E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 µL) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataIC50: 3.57E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 µL) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataIC50: >8.00E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 µL) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataIC50: >8.00E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 µL) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataIC50: >8.00E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 µL) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataIC50: >8.00E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 µL) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataIC50: >8.00E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 µL) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataIC50: >8.00E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 µL) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataIC50: >8.00E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 µL) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataIC50: >8.00E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 µL) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataIC50: >8.00E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 µL) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataIC50: >8.00E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 µL) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataIC50: >8.00E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 µL) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataKi: >1.00E+3nM ΔG°: >-34.2kJ/molepH: 7.0 T: 2°CAssay Description:PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in DMG buffer (50 mM DMG, pH 7.0, 1 mM EDTA, 150 mM NaCl, 2 mM DTT, 0.1 ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataKi: 1.17E+4nM ΔG°: -28.1kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataKi: 1.17E+4nM ΔG°: -28.1kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataKi: 1.23E+4nM ΔG°: -28.0kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataKi: 1.29E+4nM ΔG°: -27.9kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataKi: 1.62E+4nM ΔG°: -27.3kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataKi: 1.81E+4nM ΔG°: -27.1kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataKi: 2.28E+4nM ΔG°: -26.5kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataKi: 2.56E+4nM ΔG°: -26.2kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataKi: 2.87E+4nM ΔG°: -25.9kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataKi: 3.23E+4nM ΔG°: -25.6kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataKi: 5.45E+4nM ΔG°: -24.3kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataKi: 9.08E+4nM ΔG°: -23.1kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataKi: 1.03E+5nM ΔG°: -22.8kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataKi: 3.88E+5nM ΔG°: -19.5kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataKi: 4.74E+5nM ΔG°: -19.0kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataKi: 5.48E+5nM ΔG°: -18.6kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataKi: 1.09E+6nM ΔG°: -16.9kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Burnham Institute For Medical Research
Burnham Institute For Medical Research
Affinity DataIC50: 800nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Burnham Institute For Medical Research
Burnham Institute For Medical Research
Affinity DataIC50: 1.58E+4nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Burnham Institute For Medical Research
Burnham Institute For Medical Research
Affinity DataIC50: 2.23E+4nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Burnham Institute For Medical Research
Burnham Institute For Medical Research
Affinity DataIC50: 4.50E+3nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Burnham Institute For Medical Research
Burnham Institute For Medical Research
Affinity DataIC50: 4.50E+3nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Burnham Institute For Medical Research
Burnham Institute For Medical Research
Affinity DataIC50: 1.19E+4nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11 [205-593](Homo sapiens (Human))
Burnham Institute For Medical Research
Burnham Institute For Medical Research
Affinity DataIC50: 4.40E+3nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair