Compile Data Set for Download or QSAR
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Found 3022 Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4A'
LigandPNGBDBM30027(BMCL181297 Compound 5A | cid_662965 | triazolothia...)
Affinity DataIC50:  40nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM30050(triazolothiadiazine, 5B)
Affinity DataIC50:  126nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM30051(triazolothiadiazine, 5C)
Affinity DataIC50:  88.9nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM30052(triazolothiadiazine, 5D)
Affinity DataIC50:  112nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM30053(triazolothiadiazine, 5E)
Affinity DataIC50:  79nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM30019(BMCL181297 Compound 5F | triazolothiadiazine, 5)
Affinity DataIC50:  10nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM30055(triazolothiadiazine, 5G)
Affinity DataIC50:  177nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM30056(triazolothiadiazine, 5H)
Affinity DataIC50:  50nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM30057(triazolothiadiazine, 5I)
Affinity DataIC50:  141nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM30058(triazolothiadiazine, 5J)
Affinity DataIC50:  50nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM30059(triazolothiadiazine, 5K)
Affinity DataIC50:  159nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM30060(triazolothiadiazine, 6A)
Affinity DataIC50:  2.00E+4nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM30061(triazolothiadiazine, 6B)
Affinity DataIC50:  1.34E+4nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM30062(triazolothiadiazine, 6C)
Affinity DataIC50:  1.41E+4nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM30063(triazolothiadiazine, 6D)
Affinity DataIC50: >2.00E+4nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM30064(triazolothiadiazine, 6E)
Affinity DataIC50:  1.97E+4nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM30065(triazolothiadiazine, 6F)
Affinity DataIC50:  1.96E+4nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM30066(triazolothiadiazine, 6G)
Affinity DataIC50:  8.90E+3nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM30067(triazolothiadiazine, 6H)
Affinity DataIC50:  1.34E+4nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM30068(triazolothiadiazine, 6I)
Affinity DataIC50:  1.41E+4nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM30069(triazolothiadiazine, 6J)
Affinity DataIC50: >2.00E+4nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM30070(triazolothiadiazine, 6K)
Affinity DataIC50: >2.00E+4nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM30071(triazolothiadiazine, 7A)
Affinity DataIC50:  1.20E+4nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM30072(triazolothiadiazine, 7B)
Affinity DataIC50:  1.26E+4nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM30073(triazolothiadiazine, 7C)
Affinity DataIC50:  8.40E+3nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM30074(triazolothiadiazine, 7D)
Affinity DataIC50: >2.00E+4nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM30075(triazolothiadiazine, 7E)
Affinity DataIC50:  1.34E+4nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM30076(triazolothiadiazine, 7F)
Affinity DataIC50:  8.00E+3nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM30077(triazolothiadiazine, 7G)
Affinity DataIC50:  9.00E+3nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM30078(triazolothiadiazine, 7H)
Affinity DataIC50:  1.34E+4nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM136697(US8865662, 1)
Affinity DataIC50:  230nMpH: 7.2Assay Description:PDE4 specifically hydrolyzes cAMP and releases the product AMP. The potency of PDE inhibition by said agents is determined in an in vitro enzymatic a...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM136698(US8865662, 2)
Affinity DataIC50:  880nMpH: 7.2Assay Description:PDE4 specifically hydrolyzes cAMP and releases the product AMP. The potency of PDE inhibition by said agents is determined in an in vitro enzymatic a...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM136699(US8865662, 3 | US9738676, WS2011/018510, Expl. 2)
Affinity DataIC50:  630nMpH: 7.2Assay Description:PDE4 specifically hydrolyzes cAMP and releases the product AMP. The potency of PDE inhibition by said agents is determined in an in vitro enzymatic a...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM136700(US8865662, 5)
Affinity DataIC50:  200nMpH: 7.2Assay Description:PDE4 specifically hydrolyzes cAMP and releases the product AMP. The potency of PDE inhibition by said agents is determined in an in vitro enzymatic a...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM136701(US8865662, 4)
Affinity DataIC50:  30nMpH: 7.2Assay Description:PDE4 specifically hydrolyzes cAMP and releases the product AMP. The potency of PDE inhibition by said agents is determined in an in vitro enzymatic a...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM30019(BMCL181297 Compound 5F | triazolothiadiazine, 5)
Affinity DataIC50:  6.70nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM30020(triazolothiadiazine, 6)
Affinity DataIC50:  13nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM30021(triazolothiadiazine, 7)
Affinity DataIC50:  6.10nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM30022(triazolothiadiazine, 8)
Affinity DataIC50:  11nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM30023(Racemic | cid_44142103 | triazolothiadiazine, 9)
Affinity DataIC50:  3.40nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM30024(triazolothiadiazine, 10)
Affinity DataIC50:  3nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM30025(triazolopyridazine, 17)
Affinity DataIC50:  7.30nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM30026(triazolopyridazine, 18)
Affinity DataIC50:  1.5nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM30027(BMCL181297 Compound 5A | cid_662965 | triazolothia...)
Affinity DataIC50:  46nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM30028(triazolothiadiazine, 22)
Affinity DataIC50:  32nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM30029(triazolothiadiazine, 23)
Affinity DataIC50:  35nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM30030(triazolothiadiazine, 24)
Affinity DataIC50:  35nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM30031(triazolothiadiazine, 25)
Affinity DataIC50:  20nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM30032(triazolothiadiazine, 26)
Affinity DataIC50:  11nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM30033(triazolothiadiazine, 27)
Affinity DataIC50:  22nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 3022 total ) | Next | Last >>
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