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Found 13 hits Enz. Inhib. hit(s) with Target = '20-alpha-Hydroxysteroid Dehydrogenase (AKR1C1)'
Target (Institution)	Ligand	Target Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	pH	Temp °C
20-alpha-Hydroxysteroid Dehydrogenase (AKR1C1) Homo sapiens	CHEBI:480305 (5-bromo-4-hydroxybiphenyl-3-carboxylic acid)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt	CHEBI CSLS PC cid PC sid	PubMed	4.000	n/a	n/a	n/a	n/a	n/a	n/a
Monash Institute of Pharmaceutical Sciences Curated by ChEMBL	CHEBI:480305 (5-bromo-4-hydroxybiphenyl-3-carboxylic acid)		CHEBI CSLS PC cid PC sid	PubMed	J Med Chem. 52: 3259-64 (2009)
20-alpha-Hydroxysteroid Dehydrogenase (AKR1C1) Homo sapiens (human)	3,5-dichlorosalicylic acid (3,5-dichloro-2-hydroxybenzoic acid)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt	CHEBI CSLS MMDB PC cid PC sid PDB	MMDB PDB PubMed	5.900	-46.96	n/a	n/a	n/a	7.4	25
Monash University			CHEBI CSLS MMDB PC cid PC sid PDB	MMDB PDB PubMed	J Med Chem. 51: 4844-8 (2008)
20-alpha-Hydroxysteroid Dehydrogenase (AKR1C1) Homo sapiens	CHEBI:560835 (3,5-Dibromosalicylic acid)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt	CHEBI CSLS PC cid PC sid	PubMed	9.000	n/a	n/a	n/a	n/a	n/a	n/a
Monash Institute of Pharmaceutical Sciences Curated by ChEMBL	CHEBI:560835 (3,5-Dibromosalicylic acid)		CHEBI CSLS PC cid PC sid	PubMed	J Med Chem. 52: 3259-64 (2009)
20-alpha-Hydroxysteroid Dehydrogenase (AKR1C1) Mutant (H222S) Homo sapiens (human)	3,5-dichlorosalicylic acid (3,5-dichloro-2-hydroxybenzoic acid)	B.MOAD GoogleScholar MMDB PDB	CHEBI CSLS MMDB PC cid PC sid PDB	MMDB PDB PubMed	58.00	-41.30	n/a	n/a	n/a	7.4	25
Monash University		B.MOAD GoogleScholar MMDB PDB	CHEBI CSLS MMDB PC cid PC sid PDB	MMDB PDB PubMed	J Med Chem. 51: 4844-8 (2008)
20-alpha-Hydroxysteroid Dehydrogenase (AKR1C1) Mutant (L54V) Homo sapiens (human)	3,5-dichlorosalicylic acid (3,5-dichloro-2-hydroxybenzoic acid)	B.MOAD GoogleScholar MMDB PDB	CHEBI CSLS MMDB PC cid PC sid PDB	MMDB PDB PubMed	85.00	-40.35	n/a	n/a	n/a	7.4	25
Monash University		B.MOAD GoogleScholar MMDB PDB	CHEBI CSLS MMDB PC cid PC sid PDB	MMDB PDB PubMed	J Med Chem. 51: 4844-8 (2008)
20-alpha-Hydroxysteroid Dehydrogenase (AKR1C1) Homo sapiens	CHEBI:290620 (5-Bromo-2-hydroxy-biphenyl-3-carboxylic acid)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt	CHEBI CSLS PC cid PC sid	PubMed	140.0	n/a	n/a	n/a	n/a	n/a	n/a
Monash Institute of Pharmaceutical Sciences Curated by ChEMBL			CHEBI CSLS PC cid PC sid	PubMed	J Med Chem. 52: 3259-64 (2009)
20-alpha-Hydroxysteroid Dehydrogenase (AKR1C1) Mutant (L306A) Homo sapiens (human)	3,5-dichlorosalicylic acid (3,5-dichloro-2-hydroxybenzoic acid)	B.MOAD GoogleScholar MMDB PDB	CHEBI CSLS MMDB PC cid PC sid PDB	MMDB PDB PubMed	270.0	-37.49	n/a	n/a	n/a	7.4	25
Monash University		B.MOAD GoogleScholar MMDB PDB	CHEBI CSLS MMDB PC cid PC sid PDB	MMDB PDB PubMed	J Med Chem. 51: 4844-8 (2008)
20-alpha-Hydroxysteroid Dehydrogenase (AKR1C1) Mutant (L308A) Homo sapiens (human)	3,5-dichlorosalicylic acid (3,5-dichloro-2-hydroxybenzoic acid)	B.MOAD GoogleScholar MMDB PDB	CHEBI CSLS MMDB PC cid PC sid PDB	MMDB PDB PubMed	2800	-31.69	n/a	n/a	n/a	7.4	25
Monash University		B.MOAD GoogleScholar MMDB PDB	CHEBI CSLS MMDB PC cid PC sid PDB	MMDB PDB PubMed	J Med Chem. 51: 4844-8 (2008)
20-alpha-Hydroxysteroid Dehydrogenase (AKR1C1) Homo sapiens	3,5-dichlorosalicylic acid (3,5-dichloro-2-hydroxybenzoic acid)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt	CHEBI CSLS MMDB PC cid PC sid PDB	MMDB PDB PubMed	n/a	n/a	6.0	n/a	n/a	n/a	n/a
Monash Institute of Pharmaceutical Sciences Curated by ChEMBL			CHEBI CSLS MMDB PC cid PC sid PDB	MMDB PDB PubMed	J Med Chem. 52: 3259-64 (2009)
20-alpha-Hydroxysteroid Dehydrogenase (AKR1C1) Homo sapiens	CHEBI:560836 (3',3'',5',5''-tetrabromophenolphthalein)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt	CHEBI CSLS PC cid PC sid	PubMed	n/a	n/a	33.0	n/a	n/a	n/a	n/a
Monash Institute of Pharmaceutical Sciences Curated by ChEMBL	CHEBI:560836 (3',3'',5',5''-tetrabromophenolphthalein)		CHEBI CSLS PC cid PC sid	PubMed	J Med Chem. 52: 3259-64 (2009)
20-alpha-Hydroxysteroid Dehydrogenase (AKR1C1) Homo sapiens	CHEBI:474182 ((3,5-dibromo-4-hydroxyphenyl)(2-ethylbenzofuran-3-...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt	CHEBI CSLS	PubMed	n/a	n/a	48.0	n/a	n/a	n/a	n/a
Monash Institute of Pharmaceutical Sciences Curated by ChEMBL			CHEBI CSLS	PubMed	J Med Chem. 52: 3259-64 (2009)
20-alpha-Hydroxysteroid Dehydrogenase (AKR1C1) Homo sapiens	CHEBI:480305 (5-bromo-4-hydroxybiphenyl-3-carboxylic acid)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt	CHEBI CSLS PC cid PC sid	PubMed	n/a	n/a	460.0	n/a	n/a	n/a	n/a
Monash Institute of Pharmaceutical Sciences Curated by ChEMBL	CHEBI:480305 (5-bromo-4-hydroxybiphenyl-3-carboxylic acid)		CHEBI CSLS PC cid PC sid	PubMed	J Med Chem. 52: 3259-64 (2009)
20-alpha-Hydroxysteroid Dehydrogenase (AKR1C1) Homo sapiens	CHEBI:560835 (3,5-Dibromosalicylic acid)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt	CHEBI CSLS PC cid PC sid	PubMed	n/a	n/a	2300.0	n/a	n/a	n/a	n/a
Monash Institute of Pharmaceutical Sciences Curated by ChEMBL	CHEBI:560835 (3,5-Dibromosalicylic acid)		CHEBI CSLS PC cid PC sid	PubMed	J Med Chem. 52: 3259-64 (2009)

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Change energy unit to: kcal/mole