BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 43 hits Enz. Inhib. hit(s) with Target = 'Acid ceramidase'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Acid ceramidase


(Homo sapiens)
BDBM29080
PNG
(CHEMBL280065 | N-oleoylethanolamine | Oleamide MEA...)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)NCCO
Show InChI InChI=1S/C20H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(23)21-18-19-22/h9-10,22H,2-8,11-19H2,1H3,(H,21,23)/b10-9-
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
5.00E+5n/an/an/an/an/an/an/an/a



Fondazione Istituto Italiano di Tecnologia

Curated by ChEMBL


Assay Description
Inhibition of acid ceramidase (unknown origin)


Citation and Details
More data for this
Ligand-Target Pair
Acid ceramidase


(Rattus norvegicus)
BDBM50431244
PNG
(CHEMBL2333064)
Show SMILES CCCCCCCCNC(=O)n1cc(F)c(=O)n(C(=O)OC)c1=O
Show InChI InChI=1S/C15H22FN3O5/c1-3-4-5-6-7-8-9-17-13(21)18-10-11(16)12(20)19(14(18)22)15(23)24-2/h10H,3-9H2,1-2H3,(H,17,21)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 4n/an/an/an/an/an/a



Fondazione Istituto Italiano di Tecnologia

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...


Citation and Details
More data for this
Ligand-Target Pair
Acid ceramidase


(Rattus norvegicus)
BDBM50431255
PNG
(CHEMBL2333053)
Show SMILES CCCCCCNC(=O)n1cc(F)c(=O)n(C(=O)OC)c1=O
Show InChI InChI=1S/C13H18FN3O5/c1-3-4-5-6-7-15-11(19)16-8-9(14)10(18)17(12(16)20)13(21)22-2/h8H,3-7H2,1-2H3,(H,15,19)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 7n/an/an/an/an/an/a



Fondazione Istituto Italiano di Tecnologia

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...


Citation and Details
More data for this
Ligand-Target Pair
Acid ceramidase


(Rattus norvegicus)
BDBM50431246
PNG
(CHEMBL2333062)
Show SMILES CCCCCCCCNC(=O)n1cc(c(=O)[nH]c1=O)C(F)(F)F
Show InChI InChI=1S/C14H20F3N3O3/c1-2-3-4-5-6-7-8-18-12(22)20-9-10(14(15,16)17)11(21)19-13(20)23/h9H,2-8H2,1H3,(H,18,22)(H,19,21,23)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 7n/an/an/an/an/an/a



Fondazione Istituto Italiano di Tecnologia

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...


Citation and Details
More data for this
Ligand-Target Pair
Acid ceramidase


(Rattus norvegicus)
BDBM50431271
PNG
(CHEMBL2333033)
Show SMILES CCCCCCNC(=O)n1cc(c(=O)[nH]c1=O)C(F)(F)F
Show InChI InChI=1S/C12H16F3N3O3/c1-2-3-4-5-6-16-10(20)18-7-8(12(13,14)15)9(19)17-11(18)21/h7H,2-6H2,1H3,(H,16,20)(H,17,19,21)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 12n/an/an/an/an/an/a



Fondazione Istituto Italiano di Tecnologia

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...


Citation and Details
More data for this
Ligand-Target Pair
Acid ceramidase


(Rattus norvegicus)
BDBM50431254
PNG
(CHEMBL2333054)
Show SMILES CCCCCCNC(=O)n1cc(F)c(=O)n(C(=O)OCC)c1=O
Show InChI InChI=1S/C14H20FN3O5/c1-3-5-6-7-8-16-12(20)17-9-10(15)11(19)18(13(17)21)14(22)23-4-2/h9H,3-8H2,1-2H3,(H,16,20)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 12n/an/an/an/an/an/a



Fondazione Istituto Italiano di Tecnologia

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...


Citation and Details
More data for this
Ligand-Target Pair
Acid ceramidase


(Rattus norvegicus)
BDBM50431260
PNG
(CHEMBL2333048)
Show SMILES CCCCCCNC(=O)n1cc(F)c(=O)n(C)c1=O
Show InChI InChI=1S/C12H18FN3O3/c1-3-4-5-6-7-14-11(18)16-8-9(13)10(17)15(2)12(16)19/h8H,3-7H2,1-2H3,(H,14,18)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 13n/an/an/an/an/an/a



Fondazione Istituto Italiano di Tecnologia

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...


Citation and Details
More data for this
Ligand-Target Pair
Acid ceramidase


(Rattus norvegicus)
BDBM50431253
PNG
(CHEMBL2333055)
Show SMILES CCCCCCNC(=O)n1cc(F)c(=O)n(C(=O)OCC(C)C)c1=O
Show InChI InChI=1S/C16H24FN3O5/c1-4-5-6-7-8-18-14(22)19-9-12(17)13(21)20(15(19)23)16(24)25-10-11(2)3/h9,11H,4-8,10H2,1-3H3,(H,18,22)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 16n/an/an/an/an/an/a



Fondazione Istituto Italiano di Tecnologia

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...


Citation and Details
More data for this
Ligand-Target Pair
Acid ceramidase


(Rattus norvegicus)
BDBM50431258
PNG
(CHEMBL2333050)
Show SMILES CCCCCCNC(=O)n1cc(F)c(=O)n(CC)c1=O
Show InChI InChI=1S/C13H20FN3O3/c1-3-5-6-7-8-15-12(19)17-9-10(14)11(18)16(4-2)13(17)20/h9H,3-8H2,1-2H3,(H,15,19)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 18n/an/an/an/an/an/a



Fondazione Istituto Italiano di Tecnologia

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...


Citation and Details
More data for this
Ligand-Target Pair
Acid ceramidase


(Rattus norvegicus)
BDBM50431252
PNG
(CHEMBL2333056)
Show SMILES CCCCCCNC(=O)n1cc(F)c(=O)n(C(=O)c2ccccc2)c1=O
Show InChI InChI=1S/C18H20FN3O4/c1-2-3-4-8-11-20-17(25)21-12-14(19)16(24)22(18(21)26)15(23)13-9-6-5-7-10-13/h5-7,9-10,12H,2-4,8,11H2,1H3,(H,20,25)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/a 20n/an/an/an/an/an/a



Fondazione Istituto Italiano di Tecnologia

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...


Citation and Details
More data for this
Ligand-Target Pair
Acid ceramidase


(Rattus norvegicus)
BDBM50431256
PNG
(CHEMBL2333052)
Show SMILES CCCCCCNC(=O)n1cc(F)c(=O)n(C(=O)C(C)C)c1=O
Show InChI InChI=1S/C15H22FN3O4/c1-4-5-6-7-8-17-14(22)18-9-11(16)13(21)19(15(18)23)12(20)10(2)3/h9-10H,4-8H2,1-3H3,(H,17,22)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 21n/an/an/an/an/an/a



Fondazione Istituto Italiano di Tecnologia

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...


Citation and Details
More data for this
Ligand-Target Pair
Acid ceramidase


(Rattus norvegicus)
BDBM50431275
PNG
(CARMOFUR | Mifurol)
Show SMILES CCCCCCNC(=O)n1cc(F)c(=O)[nH]c1=O
Show InChI InChI=1S/C11H16FN3O3/c1-2-3-4-5-6-13-10(17)15-7-8(12)9(16)14-11(15)18/h7H,2-6H2,1H3,(H,13,17)(H,14,16,18)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 29n/an/an/an/an/an/a



Fondazione Istituto Italiano di Tecnologia

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...


Citation and Details
More data for this
Ligand-Target Pair
Acid ceramidase


(Rattus norvegicus)
BDBM50431248
PNG
(CHEMBL2333060)
Show SMILES CCCCCCCCNC(=O)n1cc(F)c(=O)[nH]c1=O
Show InChI InChI=1S/C13H20FN3O3/c1-2-3-4-5-6-7-8-15-12(19)17-9-10(14)11(18)16-13(17)20/h9H,2-8H2,1H3,(H,15,19)(H,16,18,20)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 46n/an/an/an/an/an/a



Fondazione Istituto Italiano di Tecnologia

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...


Citation and Details
More data for this
Ligand-Target Pair
Acid ceramidase


(Rattus norvegicus)
BDBM50431262
PNG
(CHEMBL2333042)
Show SMILES CCCCCCNC(=O)n1cc(Br)c(=O)[nH]c1=O
Show InChI InChI=1S/C11H16BrN3O3/c1-2-3-4-5-6-13-10(17)15-7-8(12)9(16)14-11(15)18/h7H,2-6H2,1H3,(H,13,17)(H,14,16,18)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 51n/an/an/an/an/an/a



Fondazione Istituto Italiano di Tecnologia

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...


Citation and Details
More data for this
Ligand-Target Pair
Acid ceramidase


(Rattus norvegicus)
BDBM50431259
PNG
(CHEMBL2333049)
Show SMILES CCCCCCNC(=O)n1ccc(=O)n(C)c1=O
Show InChI InChI=1S/C12H19N3O3/c1-3-4-5-6-8-13-11(17)15-9-7-10(16)14(2)12(15)18/h7,9H,3-6,8H2,1-2H3,(H,13,17)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 53n/an/an/an/an/an/a



Fondazione Istituto Italiano di Tecnologia

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...


Citation and Details
More data for this
Ligand-Target Pair
Acid ceramidase


(Rattus norvegicus)
BDBM50431257
PNG
(CHEMBL2333051)
Show SMILES CCCCCCNC(=O)n1cc(F)c(=O)n(CC2CC2)c1=O
Show InChI InChI=1S/C15H22FN3O3/c1-2-3-4-5-8-17-14(21)19-10-12(16)13(20)18(15(19)22)9-11-6-7-11/h10-11H,2-9H2,1H3,(H,17,21)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 61n/an/an/an/an/an/a



Fondazione Istituto Italiano di Tecnologia

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...


Citation and Details
More data for this
Ligand-Target Pair
Acid ceramidase


(Rattus norvegicus)
BDBM50431272
PNG
(CHEMBL2333032)
Show SMILES CCCCCCNC(=O)n1cc(Cl)c(=O)[nH]c1=O
Show InChI InChI=1S/C11H16ClN3O3/c1-2-3-4-5-6-13-10(17)15-7-8(12)9(16)14-11(15)18/h7H,2-6H2,1H3,(H,13,17)(H,14,16,18)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 67n/an/an/an/an/an/a



Fondazione Istituto Italiano di Tecnologia

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...


Citation and Details
More data for this
Ligand-Target Pair
Acid ceramidase


(Rattus norvegicus)
BDBM50431263
PNG
(CHEMBL2333041)
Show SMILES CCCCCCNC(=O)n1cc(I)c(=O)[nH]c1=O
Show InChI InChI=1S/C11H16IN3O3/c1-2-3-4-5-6-13-10(17)15-7-8(12)9(16)14-11(15)18/h7H,2-6H2,1H3,(H,13,17)(H,14,16,18)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 147n/an/an/an/an/an/a



Fondazione Istituto Italiano di Tecnologia

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...


Citation and Details
More data for this
Ligand-Target Pair
Acid ceramidase


(Rattus norvegicus)
BDBM50431264
PNG
(CHEMBL2333040)
Show SMILES CCCCCCNC(=O)n1cc(-c2ccccc2)c(=O)[nH]c1=O
Show InChI InChI=1S/C17H21N3O3/c1-2-3-4-8-11-18-16(22)20-12-14(15(21)19-17(20)23)13-9-6-5-7-10-13/h5-7,9-10,12H,2-4,8,11H2,1H3,(H,18,22)(H,19,21,23)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/a 177n/an/an/an/an/an/a



Fondazione Istituto Italiano di Tecnologia

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...


Citation and Details
More data for this
Ligand-Target Pair
Acid ceramidase


(Rattus norvegicus)
BDBM50431247
PNG
(CHEMBL2333061)
Show SMILES CCCCCCCCNC(=O)n1ccc(=O)[nH]c1=O
Show InChI InChI=1S/C13H21N3O3/c1-2-3-4-5-6-7-9-14-12(18)16-10-8-11(17)15-13(16)19/h8,10H,2-7,9H2,1H3,(H,14,18)(H,15,17,19)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 283n/an/an/an/an/an/a



Fondazione Istituto Italiano di Tecnologia

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...


Citation and Details
More data for this
Ligand-Target Pair
Acid ceramidase


(Rattus norvegicus)
BDBM50431249
PNG
(CHEMBL2333059)
Show SMILES CCCCCCCNC(=O)n1ccc(=O)[nH]c1=O
Show InChI InChI=1S/C12H19N3O3/c1-2-3-4-5-6-8-13-11(17)15-9-7-10(16)14-12(15)18/h7,9H,2-6,8H2,1H3,(H,13,17)(H,14,16,18)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 325n/an/an/an/an/an/a



Fondazione Istituto Italiano di Tecnologia

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...


Citation and Details
More data for this
Ligand-Target Pair
Acid ceramidase


(Rattus norvegicus)
BDBM50431269
PNG
(CHEMBL2333035)
Show SMILES CCCCCCNC(=O)n1cc(CO)c(=O)[nH]c1=O
Show InChI InChI=1S/C12H19N3O4/c1-2-3-4-5-6-13-11(18)15-7-9(8-16)10(17)14-12(15)19/h7,16H,2-6,8H2,1H3,(H,13,18)(H,14,17,19)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 417n/an/an/an/an/an/a



Fondazione Istituto Italiano di Tecnologia

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...


Citation and Details
More data for this
Ligand-Target Pair
Acid ceramidase


(Rattus norvegicus)
BDBM50431274
PNG
(CHEMBL2333065)
Show SMILES CCCCCCNC(=O)n1ccc(=O)[nH]c1=O
Show InChI InChI=1S/C11H17N3O3/c1-2-3-4-5-7-12-10(16)14-8-6-9(15)13-11(14)17/h6,8H,2-5,7H2,1H3,(H,12,16)(H,13,15,17)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 426n/an/an/an/an/an/a



Fondazione Istituto Italiano di Tecnologia

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...


Citation and Details
More data for this
Ligand-Target Pair
Acid ceramidase


(Rattus norvegicus)
BDBM50431245
PNG
(CHEMBL2333063)
Show SMILES CCCCCCCCCNC(=O)n1ccc(=O)[nH]c1=O
Show InChI InChI=1S/C14H23N3O3/c1-2-3-4-5-6-7-8-10-15-13(19)17-11-9-12(18)16-14(17)20/h9,11H,2-8,10H2,1H3,(H,15,19)(H,16,18,20)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 464n/an/an/an/an/an/a



Fondazione Istituto Italiano di Tecnologia

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...


Citation and Details
More data for this
Ligand-Target Pair
Acid ceramidase


(Rattus norvegicus)
BDBM50431270
PNG
(CHEMBL2333034)
Show SMILES CCCCCCNC(=O)n1cc(CC)c(=O)[nH]c1=O
Show InChI InChI=1S/C13H21N3O3/c1-3-5-6-7-8-14-12(18)16-9-10(4-2)11(17)15-13(16)19/h9H,3-8H2,1-2H3,(H,14,18)(H,15,17,19)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 733n/an/an/an/an/an/a



Fondazione Istituto Italiano di Tecnologia

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...


Citation and Details
More data for this
Ligand-Target Pair
Acid ceramidase


(Rattus norvegicus)
BDBM50431266
PNG
(CHEMBL2333038)
Show SMILES CCCCCCNC(=O)n1cc(N2CCOCC2)c(=O)[nH]c1=O
Show InChI InChI=1S/C15H24N4O4/c1-2-3-4-5-6-16-14(21)19-11-12(13(20)17-15(19)22)18-7-9-23-10-8-18/h11H,2-10H2,1H3,(H,16,21)(H,17,20,22)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 875n/an/an/an/an/an/a



Fondazione Istituto Italiano di Tecnologia

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...


Citation and Details
More data for this
Ligand-Target Pair
Acid ceramidase


(Homo sapiens)
BDBM50392473
PNG
(CHEMBL429926)
Show SMILES CCCCCCCCCCCCCC(=O)N[C@H](C)[C@@H](O)c1ccccc1
Show InChI InChI=1S/C23H39NO2/c1-3-4-5-6-7-8-9-10-11-12-16-19-22(25)24-20(2)23(26)21-17-14-13-15-18-21/h13-15,17-18,20,23,26H,3-12,16,19H2,1-2H3,(H,24,25)/t20-,23-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.00E+3n/an/an/an/an/an/a



Humboldt Universit£t zu Berlin

Curated by ChEMBL


Assay Description
Inhibition of aCDase expressed in human HL60 cell extract


Citation and Details
More data for this
Ligand-Target Pair
Acid ceramidase


(Rattus norvegicus)
BDBM50431268
PNG
(CHEMBL2333036)
Show SMILES CCCCCCNC(=O)n1cc(OC)c(=O)[nH]c1=O
Show InChI InChI=1S/C12H19N3O4/c1-3-4-5-6-7-13-11(17)15-8-9(19-2)10(16)14-12(15)18/h8H,3-7H2,1-2H3,(H,13,17)(H,14,16,18)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/a 1.10E+3n/an/an/an/an/an/a



Fondazione Istituto Italiano di Tecnologia

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...


Citation and Details
More data for this
Ligand-Target Pair
Acid ceramidase


(Rattus norvegicus)
BDBM50431265
PNG
(CHEMBL2333039)
Show SMILES CCCCCCNC(=O)n1cc(N2CCN(C)CC2)c(=O)[nH]c1=O
Show InChI InChI=1S/C16H27N5O3/c1-3-4-5-6-7-17-15(23)21-12-13(14(22)18-16(21)24)20-10-8-19(2)9-11-20/h12H,3-11H2,1-2H3,(H,17,23)(H,18,22,24)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.40E+3n/an/an/an/an/an/a



Fondazione Istituto Italiano di Tecnologia

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...


Citation and Details
More data for this
Ligand-Target Pair
Acid ceramidase


(Rattus norvegicus)
BDBM50431273
PNG
(CHEMBL2333031)
Show SMILES CCCCCCNC(=O)n1cc(C)c(=O)[nH]c1=O
Show InChI InChI=1S/C12H19N3O3/c1-3-4-5-6-7-13-11(17)15-8-9(2)10(16)14-12(15)18/h8H,3-7H2,1-2H3,(H,13,17)(H,14,16,18)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.46E+3n/an/an/an/an/an/a



Fondazione Istituto Italiano di Tecnologia

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...


Citation and Details
More data for this
Ligand-Target Pair
Acid ceramidase


(Rattus norvegicus)
BDBM50431250
PNG
(CHEMBL2333058)
Show SMILES CCCCCNC(=O)n1ccc(=O)[nH]c1=O
Show InChI InChI=1S/C10H15N3O3/c1-2-3-4-6-11-9(15)13-7-5-8(14)12-10(13)16/h5,7H,2-4,6H2,1H3,(H,11,15)(H,12,14,16)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 2.10E+3n/an/an/an/an/an/a



Fondazione Istituto Italiano di Tecnologia

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...


Citation and Details
More data for this
Ligand-Target Pair
Acid ceramidase


(Rattus norvegicus)
BDBM50431261
PNG
(CHEMBL2333044)
Show SMILES CCCCCCNC(=O)n1cc(NC)c(=O)[nH]c1=O
Show InChI InChI=1S/C12H20N4O3/c1-3-4-5-6-7-14-11(18)16-8-9(13-2)10(17)15-12(16)19/h8,13H,3-7H2,1-2H3,(H,14,18)(H,15,17,19)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 3.40E+3n/an/an/an/an/an/a



Fondazione Istituto Italiano di Tecnologia

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...


Citation and Details
More data for this
Ligand-Target Pair
Acid ceramidase


(Rattus norvegicus)
BDBM50431267
PNG
(CHEMBL2333037)
Show SMILES CCCCCCNC(=O)n1cc(N(C)Cc2ccccc2)c(=O)[nH]c1=O
Show InChI InChI=1S/C19H26N4O3/c1-3-4-5-9-12-20-18(25)23-14-16(17(24)21-19(23)26)22(2)13-15-10-7-6-8-11-15/h6-8,10-11,14H,3-5,9,12-13H2,1-2H3,(H,20,25)(H,21,24,26)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 5.50E+3n/an/an/an/an/an/a



Fondazione Istituto Italiano di Tecnologia

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...


Citation and Details
More data for this
Ligand-Target Pair
Acid ceramidase


(Rattus norvegicus)
BDBM50431251
PNG
(CHEMBL2333057)
Show SMILES CCCCNC(=O)n1ccc(=O)[nH]c1=O
Show InChI InChI=1S/C9H13N3O3/c1-2-3-5-10-8(14)12-6-4-7(13)11-9(12)15/h4,6H,2-3,5H2,1H3,(H,10,14)(H,11,13,15)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 8.50E+3n/an/an/an/an/an/a



Fondazione Istituto Italiano di Tecnologia

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...


Citation and Details
More data for this
Ligand-Target Pair
Acid ceramidase


(Homo sapiens)
BDBM50392472
PNG
(CHEMBL408217)
Show SMILES CCCCCCCCCCCCCC(=O)N[C@H](CO)[C@H](O)c1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C23H38N2O5/c1-2-3-4-5-6-7-8-9-10-11-12-13-22(27)24-21(18-26)23(28)19-14-16-20(17-15-19)25(29)30/h14-17,21,23,26,28H,2-13,18H2,1H3,(H,24,27)/t21-,23-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/a 1.00E+4n/an/an/an/an/an/a



Humboldt Universit£t zu Berlin

Curated by ChEMBL


Assay Description
Inhibition of aCDase


Citation and Details
More data for this
Ligand-Target Pair
Acid ceramidase


(Homo sapiens)
BDBM50392472
PNG
(CHEMBL408217)
Show SMILES CCCCCCCCCCCCCC(=O)N[C@H](CO)[C@H](O)c1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C23H38N2O5/c1-2-3-4-5-6-7-8-9-10-11-12-13-22(27)24-21(18-26)23(28)19-14-16-20(17-15-19)25(29)30/h14-17,21,23,26,28H,2-13,18H2,1H3,(H,24,27)/t21-,23-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/a 1.00E+4n/an/an/an/an/an/a



Fondazione Istituto Italiano di Tecnologia

Curated by ChEMBL


Assay Description
Inhibition of acid ceramidase (unknown origin)


Citation and Details
More data for this
Ligand-Target Pair
Acid ceramidase


(Homo sapiens)
BDBM50392472
PNG
(CHEMBL408217)
Show SMILES CCCCCCCCCCCCCC(=O)N[C@H](CO)[C@H](O)c1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C23H38N2O5/c1-2-3-4-5-6-7-8-9-10-11-12-13-22(27)24-21(18-26)23(28)19-14-16-20(17-15-19)25(29)30/h14-17,21,23,26,28H,2-13,18H2,1H3,(H,24,27)/t21-,23-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/a 2.77E+4n/an/an/an/an/an/a



Medical University of South Carolina

Curated by ChEMBL


Assay Description
Inhibition of ACDase in human MCF7 cell lysate using [9,10-3H] De-C16-Cer substrate after 1 hr by scintillation counting analysis


Citation and Details
More data for this
Ligand-Target Pair
Acid ceramidase


(Homo sapiens)
BDBM50382315
PNG
(CHEMBL2024682)
Show SMILES CCCCCCCCCCCCCS\C=C\[C@H](CO)NC(=O)C(C)(C)C
Show InChI InChI=1S/C22H43NO2S/c1-5-6-7-8-9-10-11-12-13-14-15-17-26-18-16-20(19-24)23-21(25)22(2,3)4/h16,18,20,24H,5-15,17,19H2,1-4H3,(H,23,25)/b18-16+/t20-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 5.10E+4n/an/an/an/an/an/a



Institute for Advanced Chemistry of Catalonia

Curated by ChEMBL


Assay Description
Inhibition of aCDase using RBM14C12 as substrate after 1 hr by HPLC-FD analysis


Citation and Details
More data for this
Ligand-Target Pair
Acid ceramidase


(Homo sapiens)
BDBM50382315
PNG
(CHEMBL2024682)
Show SMILES CCCCCCCCCCCCCS\C=C\[C@H](CO)NC(=O)C(C)(C)C
Show InChI InChI=1S/C22H43NO2S/c1-5-6-7-8-9-10-11-12-13-14-15-17-26-18-16-20(19-24)23-21(25)22(2,3)4/h16,18,20,24H,5-15,17,19H2,1-4H3,(H,23,25)/b18-16+/t20-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 5.10E+4n/an/an/an/an/an/a



Institute for Advanced Chemistry of Catalonia

Curated by ChEMBL


Assay Description
Inhibition of aCDase in Moh.pAS AcCer10X cells using RBM14C12 as substrate after 1 hr by HPLC-FD analysis


Citation and Details
More data for this
Ligand-Target Pair
Acid ceramidase


(Homo sapiens)
BDBM50382314
PNG
(CHEMBL2024680)
Show SMILES CCCCCCCCCCCCCS\C=C\[C@H](CO)NC(=O)CCCCCCC
Show InChI InChI=1S/C25H49NO2S/c1-3-5-7-9-10-11-12-13-14-16-18-21-29-22-20-24(23-27)26-25(28)19-17-15-8-6-4-2/h20,22,24,27H,3-19,21,23H2,1-2H3,(H,26,28)/b22-20+/t24-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 7.70E+4n/an/an/an/an/an/a



Institute for Advanced Chemistry of Catalonia

Curated by ChEMBL


Assay Description
Inhibition of aCDase using RBM14C12 as substrate after 1 hr by HPLC-FD analysis


Citation and Details
More data for this
Ligand-Target Pair
Acid ceramidase


(Homo sapiens)
BDBM50382314
PNG
(CHEMBL2024680)
Show SMILES CCCCCCCCCCCCCS\C=C\[C@H](CO)NC(=O)CCCCCCC
Show InChI InChI=1S/C25H49NO2S/c1-3-5-7-9-10-11-12-13-14-16-18-21-29-22-20-24(23-27)26-25(28)19-17-15-8-6-4-2/h20,22,24,27H,3-19,21,23H2,1-2H3,(H,26,28)/b22-20+/t24-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 7.70E+4n/an/an/an/an/an/a



Institute for Advanced Chemistry of Catalonia

Curated by ChEMBL


Assay Description
Inhibition of aCDase in Moh.pAS AcCer10X cells using RBM14C12 as substrate after 1 hr by HPLC-FD analysis


Citation and Details
More data for this
Ligand-Target Pair
Acid ceramidase


(Homo sapiens)
BDBM50382316
PNG
(CHEMBL2024681)
Show SMILES CCCCCCCCCCCCCS\C=C\[C@H](CO)NC(=O)c1ccc(cc1)C(C)(C)C
Show InChI InChI=1S/C28H47NO2S/c1-5-6-7-8-9-10-11-12-13-14-15-21-32-22-20-26(23-30)29-27(31)24-16-18-25(19-17-24)28(2,3)4/h16-20,22,26,30H,5-15,21,23H2,1-4H3,(H,29,31)/b22-20+/t26-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/a 3.15E+5n/an/an/an/an/an/a



Institute for Advanced Chemistry of Catalonia

Curated by ChEMBL


Assay Description
Inhibition of aCDase in Moh.pAS AcCer10X cells using RBM14C12 as substrate after 1 hr by HPLC-FD analysis


Citation and Details
More data for this
Ligand-Target Pair
Acid ceramidase


(Homo sapiens)
BDBM50382316
PNG
(CHEMBL2024681)
Show SMILES CCCCCCCCCCCCCS\C=C\[C@H](CO)NC(=O)c1ccc(cc1)C(C)(C)C
Show InChI InChI=1S/C28H47NO2S/c1-5-6-7-8-9-10-11-12-13-14-15-21-32-22-20-26(23-30)29-27(31)24-16-18-25(19-17-24)28(2,3)4/h16-20,22,26,30H,5-15,21,23H2,1-4H3,(H,29,31)/b22-20+/t26-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/a 3.15E+5n/an/an/an/an/an/a



Institute for Advanced Chemistry of Catalonia

Curated by ChEMBL


Assay Description
Inhibition of aCDase using RBM14C12 as substrate after 1 hr by HPLC-FD analysis


Citation and Details
More data for this
Ligand-Target Pair