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Compile Data Set for Download or QSAR

Found 598 hits Enz. Inhib. hit(s) with Target = 'Beta-galactosidase'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Beta-galactosidase


(Escherichia coli)
BDBM50140062
PNG
(CHEMBL3359672)
PDB
MMDB

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0.0600n/an/an/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Beta-galactosidase


(Escherichia coli)
BDBM50140061
PNG
(CHEMBL3752112)
PDB
MMDB

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1.30n/an/an/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Beta-galactosidase


(Escherichia coli)
BDBM50150470
PNG
(CHEMBL3771185)
PDB
MMDB

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2.90n/an/an/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
β-galactosidase


(Bos taurus (Bovine))
BDBM50133507
PNG
(4-Decylamino-6-methyl-cyclohexane-1,2,3-triol | CH...)
Show SMILES CCCCCCCCCCNC1CC(C)C(O)C(O)C1O
Show InChI InChI=1S/C17H35NO3/c1-3-4-5-6-7-8-9-10-11-18-14-12-13(2)15(19)17(21)16(14)20/h13-21H,3-12H2,1-2H3
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9n/an/an/an/an/an/an/an/a



Keio University

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound against beta-galactosidase in bovine liver


Bioorg Med Chem Lett 13: 3461-3 (2003)

More data for this
Ligand-Target Pair
Beta-galactosidase


(Bos taurus (Bovine))
BDBM50150470
PNG
(CHEMBL3771185)
KEGG

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13n/an/an/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Beta-galactosidase


(Escherichia coli)
BDBM50350758
PNG
(CHEMBL1818433)
Show SMILES OC[C@H]1CNC[C@@H](O)[C@H]1O
Show InChI InChI=1S/C6H13NO3/c8-3-4-1-7-2-5(9)6(4)10/h4-10H,1-3H2/t4-,5-,6+/m1/s1
PDB
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31n/an/an/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Beta-galactosidase


(Escherichia coli)
BDBM50140059
PNG
(CHEMBL3753015)
PDB
MMDB

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32n/an/an/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Beta-galactosidase


(Escherichia coli)
BDBM50140060
PNG
(CHEMBL3754250)
PDB
MMDB

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42n/an/an/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
β-galactosidase


(Bos taurus (Bovine))
BDBM50133504
PNG
(4-Methyl-6-(4-phenyl-butylamino)-cyclohexane-1,2,3...)
Show SMILES CC1CC(NCCCCc2ccccc2)C(O)C(O)C1O
Show InChI InChI=1S/C17H27NO3/c1-12-11-14(16(20)17(21)15(12)19)18-10-6-5-9-13-7-3-2-4-8-13/h2-4,7-8,12,14-21H,5-6,9-11H2,1H3
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46n/an/an/an/an/an/an/an/a



Keio University

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound against beta-galactosidase in bovine liver


Bioorg Med Chem Lett 13: 3461-3 (2003)

More data for this
Ligand-Target Pair
Beta-galactosidase


(Escherichia coli)
BDBM50150471
PNG
(CHEMBL3770764)
PDB
MMDB

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49n/an/an/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
β-galactosidase


(Bos taurus (Bovine))
BDBM50118923
PNG
((1S,2S,3R)-4-Methyl-6-octylamino-cyclohexane-1,2,3...)
Show SMILES CCCCCCCCNC1CC(C)C(O)C(O)C1O
Show InChI InChI=1S/C15H31NO3/c1-3-4-5-6-7-8-9-16-12-10-11(2)13(17)15(19)14(12)18/h11-19H,3-10H2,1-2H3
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110n/an/an/an/an/an/an/an/a



Keio University

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound against beta-galactosidase in bovine liver


Bioorg Med Chem Lett 13: 3461-3 (2003)

More data for this
Ligand-Target Pair
β-galactosidase


(Bos taurus (Bovine))
BDBM50124579
PNG
(CHEMBL3621532)
Show SMILES OC[C@]12CCC(=O)N1C[C@H](O)[C@@H](O)[C@@H]2O
Show InChI InChI=1/C9H15NO5/c11-4-9-2-1-6(13)10(9)3-5(12)7(14)8(9)15/h5,7-8,11-12,14-15H,1-4H2/t5-,7+,8-,9-/s2
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200n/an/an/an/an/an/an/an/a



Savitribai Phule Pune University (formerly University of Pune)

Curated by ChEMBL


Assay Description
Inhibition of bovine liver beta-galactosidase using 10 mM p-nitrophenyl-beta-D-galactopyranoside as substrate


J Med Chem 58: 7820-32 (2015)

More data for this
Ligand-Target Pair
Beta-galactosidase


(Escherichia coli (strain K12))
BDBM50182795
PNG
(5-(dimethylamino)-N-(6-((2R,3S,4R,5S)-3,4,5-trihyd...)
Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)NCCCCCCN1C[C@H](O)[C@@H](O)[C@@H](O)[C@H]1CO
Show InChI InChI=1S/C24H37N3O6S/c1-26(2)19-11-7-10-18-17(19)9-8-12-22(18)34(32,33)25-13-5-3-4-6-14-27-15-21(29)24(31)23(30)20(27)16-28/h7-12,20-21,23-25,28-31H,3-6,13-16H2,1-2H3/t20-,21+,23+,24-/m1/s1
PDB
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220n/an/an/an/an/an/an/an/a



Industrial Research Limited

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli beta-galactosidase assessed as inhibition of nitrophenolate release by spectrophotometry


Citation and Details
More data for this
Ligand-Target Pair
Beta-galactosidase


(Escherichia coli (strain K12))
BDBM50356096
PNG
(CHEMBL1911831)
Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)NCCCCCCNC(=O)CCCCCN1C[C@H](O)[C@@H](O)[C@@H](O)[C@H]1CO
Show InChI InChI=1S/C30H48N4O7S/c1-33(2)24-14-10-13-23-22(24)12-11-15-27(23)42(40,41)32-18-8-4-3-7-17-31-28(37)16-6-5-9-19-34-20-26(36)30(39)29(38)25(34)21-35/h10-15,25-26,29-30,32,35-36,38-39H,3-9,16-21H2,1-2H3,(H,31,37)/t25-,26+,29+,30-/m1/s1
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270n/an/an/an/an/an/an/an/a



Industrial Research Limited

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli beta-galactosidase assessed as inhibition of nitrophenolate release by spectrophotometry


Citation and Details
More data for this
Ligand-Target Pair
Beta-galactosidase


(Escherichia coli)
BDBM50150472
PNG
(CHEMBL3770736)
PDB
MMDB

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280n/an/an/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Beta-galactosidase


(Homo sapiens)
BDBM50182795
PNG
(5-(dimethylamino)-N-(6-((2R,3S,4R,5S)-3,4,5-trihyd...)
Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)NCCCCCCN1C[C@H](O)[C@@H](O)[C@@H](O)[C@H]1CO
Show InChI InChI=1S/C24H37N3O6S/c1-26(2)19-11-7-10-18-17(19)9-8-12-22(18)34(32,33)25-13-5-3-4-6-14-27-15-21(29)24(31)23(30)20(27)16-28/h7-12,20-21,23-25,28-31H,3-6,13-16H2,1-2H3/t20-,21+,23+,24-/m1/s1
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300n/an/an/an/an/an/an/an/a



Industrial Research Limited

Curated by ChEMBL


Assay Description
Inhibition of human lysosomal beta-galactosidase assessed as inhibition of hydrolyzed 4-methylumbelliferone production after 30 mins by luminescence ...


Citation and Details
More data for this
Ligand-Target Pair
Beta-galactosidase


(Homo sapiens)
BDBM50358321
PNG
(CHEMBL1922579 | CHEMBL1922581)
Show SMILES CCCCCCCCN[C@@H]1C=C(CO)[C@H](O)[C@H](O)[C@H]1O
Show InChI InChI=1S/C15H29NO4/c1-2-3-4-5-6-7-8-16-12-9-11(10-17)13(18)15(20)14(12)19/h9,12-20H,2-8,10H2,1H3/t12-,13+,14+,15+/m1/s1
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300n/an/an/an/an/an/an/an/a



Amicus Therapeutics

Curated by ChEMBL


Assay Description
Inhibition of human beta galactosidase


Citation and Details
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
β-galactosidase


(Bos taurus (Bovine))
BDBM50124583
PNG
(CHEMBL3621209)
Show SMILES OC[C@@]12CCCN1C[C@@H](O)[C@@H](O)[C@@H]2O
Show InChI InChI=1/C9H17NO4/c11-5-9-2-1-3-10(9)4-6(12)7(13)8(9)14/h6-8,11-14H,1-5H2/t6-,7-,8+,9-/s2
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500n/an/an/an/an/an/an/an/a



Savitribai Phule Pune University (formerly University of Pune)

Curated by ChEMBL


Assay Description
Inhibition of bovine liver beta-galactosidase using 10 mM p-nitrophenyl-beta-D-galactopyranoside as substrate


J Med Chem 58: 7820-32 (2015)

More data for this
Ligand-Target Pair
Beta-galactosidase


(Homo sapiens)
BDBM50246569
PNG
(CHEMBL505422 | Methyl 6-[N2-dansyl-N6-(1,5-dideoxy...)
Show SMILES COC(=O)CCCCCNC(=O)[C@H](CCCCN1C[C@H](O)[C@@H](O)[C@@H](O)[C@H]1CO)NS(=O)(=O)c1cccc2c(cccc12)N(C)C
Show InChI InChI=1S/C31H48N4O9S/c1-34(2)24-14-9-12-22-21(24)11-10-15-27(22)45(42,43)33-23(31(41)32-17-7-4-5-16-28(38)44-3)13-6-8-18-35-19-26(37)30(40)29(39)25(35)20-36/h9-12,14-15,23,25-26,29-30,33,36-37,39-40H,4-8,13,16-20H2,1-3H3,(H,32,41)/t23-,25+,26-,29-,30+/m0/s1
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600n/an/an/an/an/an/an/an/a



Industrial Research Limited

Curated by ChEMBL


Assay Description
Inhibition of human lysosomal beta-galactosidase assessed as inhibition of hydrolyzed 4-methylumbelliferone production after 30 mins by luminescence ...


Citation and Details
More data for this
Ligand-Target Pair
Beta-galactosidase


(Homo sapiens)
BDBM50356097
PNG
(CHEMBL461161)
Show SMILES COC(=O)[C@H](CCCCN1C[C@H](O)[C@@H](O)[C@@H](O)[C@H]1CO)NS(=O)(=O)c1cccc2c(cccc12)N(C)C
Show InChI InChI=1S/C25H37N3O8S/c1-27(2)19-11-6-9-17-16(19)8-7-12-22(17)37(34,35)26-18(25(33)36-3)10-4-5-13-28-14-21(30)24(32)23(31)20(28)15-29/h6-9,11-12,18,20-21,23-24,26,29-32H,4-5,10,13-15H2,1-3H3/t18-,20+,21-,23-,24+/m0/s1
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700n/an/an/an/an/an/an/an/a



Industrial Research Limited

Curated by ChEMBL


Assay Description
Inhibition of human lysosomal beta-galactosidase assessed as inhibition of hydrolyzed 4-methylumbelliferone production after 30 mins by luminescence ...


Citation and Details
More data for this
Ligand-Target Pair
Beta-galactosidase


(Homo sapiens)
BDBM50356096
PNG
(CHEMBL1911831)
Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)NCCCCCCNC(=O)CCCCCN1C[C@H](O)[C@@H](O)[C@@H](O)[C@H]1CO
Show InChI InChI=1S/C30H48N4O7S/c1-33(2)24-14-10-13-23-22(24)12-11-15-27(23)42(40,41)32-18-8-4-3-7-17-31-28(37)16-6-5-9-19-34-20-26(36)30(39)29(38)25(34)21-35/h10-15,25-26,29-30,32,35-36,38-39H,3-9,16-21H2,1-2H3,(H,31,37)/t25-,26+,29+,30-/m1/s1
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700n/an/an/an/an/an/an/an/a



Industrial Research Limited

Curated by ChEMBL


Assay Description
Inhibition of human lysosomal beta-galactosidase assessed as inhibition of hydrolyzed 4-methylumbelliferone production after 30 mins by luminescence ...


Citation and Details
More data for this
Ligand-Target Pair
Beta-galactosidase


(Bos taurus (Bovine))
BDBM50358321
PNG
(CHEMBL1922579 | CHEMBL1922581)
Show SMILES CCCCCCCCN[C@@H]1C=C(CO)[C@H](O)[C@H](O)[C@H]1O
Show InChI InChI=1S/C15H29NO4/c1-2-3-4-5-6-7-8-16-12-9-11(10-17)13(18)15(20)14(12)19/h9,12-20H,2-8,10H2,1H3/t12-,13+,14+,15+/m1/s1
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870n/an/an/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
beta-Galactosidase (β-Gal)(R201C)


(Homo sapiens (Human))
BDBM228800
PNG
(NOEV | Sapienic acid (SpA))
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940 -35.8n/an/an/an/an/a4.537


TBA



Citation and Details
More data for this
Ligand-Target Pair
Beta-galactosidase


(Rhizobium meliloti)
BDBM50182795
PNG
(5-(dimethylamino)-N-(6-((2R,3S,4R,5S)-3,4,5-trihyd...)
Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)NCCCCCCN1C[C@H](O)[C@@H](O)[C@@H](O)[C@H]1CO
Show InChI InChI=1S/C24H37N3O6S/c1-26(2)19-11-7-10-18-17(19)9-8-12-22(18)34(32,33)25-13-5-3-4-6-14-27-15-21(29)24(31)23(30)20(27)16-28/h7-12,20-21,23-25,28-31H,3-6,13-16H2,1-2H3/t20-,21+,23+,24-/m1/s1
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950n/an/an/an/an/an/an/an/a



Technische Universität Graz

Curated by ChEMBL


Assay Description
Inhibition of Agrobacterium sp. beta-galactosidase


Citation and Details
More data for this
Ligand-Target Pair
β-galactosidase


(Bos taurus (Bovine))
BDBM50124581
PNG
(CHEMBL3621529)
Show SMILES OC[C@@]12CCCN1C[C@H](O)[C@@H](O)[C@@H]2O
Show InChI InChI=1/C9H17NO4/c11-5-9-2-1-3-10(9)4-6(12)7(13)8(9)14/h6-8,11-14H,1-5H2/t6-,7+,8-,9+/s2
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1.00E+3n/an/an/an/an/an/an/an/a



Savitribai Phule Pune University (formerly University of Pune)

Curated by ChEMBL


Assay Description
Inhibition of bovine liver beta-galactosidase using 10 mM p-nitrophenyl-beta-D-galactopyranoside as substrate


J Med Chem 58: 7820-32 (2015)

More data for this
Ligand-Target Pair
beta-Galactosidase (β-Gal)


(Homo sapiens (Human))
BDBM228800
PNG
(NOEV | Sapienic acid (SpA))
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1.10E+3 -35.4n/an/an/an/an/a4.537


TBA



Citation and Details
More data for this
Ligand-Target Pair
beta-Galactosidase (β-Gal)(I51T)


(Homo sapiens (Human))
BDBM228800
PNG
(NOEV | Sapienic acid (SpA))
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1.20E+3 -35.2n/an/an/an/an/a4.537


TBA



Citation and Details
More data for this
Ligand-Target Pair
β-galactosidase


(Bos taurus (Bovine))
BDBM50124582
PNG
(CHEMBL3621528)
Show SMILES OC[C@]12CCCN1C[C@H](O)[C@@H](O)[C@@H]2O
Show InChI InChI=1/C9H17NO4/c11-5-9-2-1-3-10(9)4-6(12)7(13)8(9)14/h6-8,11-14H,1-5H2/t6-,7+,8-,9-/s2
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1.50E+3n/an/an/an/an/an/an/an/a



Savitribai Phule Pune University (formerly University of Pune)

Curated by ChEMBL


Assay Description
Inhibition of bovine liver beta-galactosidase using 10 mM p-nitrophenyl-beta-D-galactopyranoside as substrate


J Med Chem 58: 7820-32 (2015)

More data for this
Ligand-Target Pair
β-galactosidase


(Bos taurus (Bovine))
BDBM50124578
PNG
(CHEMBL3621533)
Show SMILES OC[C@@]12CCC(=O)N1C[C@H](O)[C@@H](O)[C@@H]2O
Show InChI InChI=1/C9H15NO5/c11-4-9-2-1-6(13)10(9)3-5(12)7(14)8(9)15/h5,7-8,11-12,14-15H,1-4H2/t5-,7+,8-,9+/s2
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2.40E+3n/an/an/an/an/an/an/an/a



Savitribai Phule Pune University (formerly University of Pune)

Curated by ChEMBL


Assay Description
Inhibition of bovine liver beta-galactosidase using 10 mM p-nitrophenyl-beta-D-galactopyranoside as substrate


J Med Chem 58: 7820-32 (2015)

More data for this
Ligand-Target Pair
beta-Galactosidase (β-gal)


(Escherichia coli (Enterobacteria))
BDBM192767
PNG
(β-gal inhibitor, 13)
Show SMILES OC[C@H]1O[C@@H](SCCOC(=O)c2ccc(cc2C(c2ccccc2)c2ccccc2)C(=O)NCCOCCOCCOCCNC(=O)c2ccc(cc2)C(=O)c2ccccc2)[C@H](O)[C@@H](O)[C@H]1O
Show InChI InChI=1/C51H56N2O13S/c54-33-42-45(56)46(57)47(58)51(66-42)67-31-30-65-50(61)40-21-20-39(32-41(40)43(34-10-4-1-5-11-34)35-12-6-2-7-13-35)49(60)53-23-25-63-27-29-64-28-26-62-24-22-52-48(59)38-18-16-37(17-19-38)44(55)36-14-8-3-9-15-36/h1-21,32,42-43,45-47,51,54,56-58H,22-31,33H2,(H,52,59)(H,53,60)/t42-,45+,46+,47-,51+/s2
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3.00E+3n/an/an/an/an/an/an/an/a



Fairfield University



Assay Description
Enzymatic activity of beta-galactosidase from Escherichia coli (1.2 x 10^-10 M) was measured using the colorimetric substrate ortho-nitrophenyl-b-g...


Citation and Details
More data for this
Ligand-Target Pair
β-galactosidase


(Bos taurus (Bovine))
BDBM50124580
PNG
(CHEMBL3621530)
Show SMILES OC[C@@]12CCC(=O)N1C[C@@H](O)[C@@H](O)[C@@H]2O
Show InChI InChI=1/C9H15NO5/c11-4-9-2-1-6(13)10(9)3-5(12)7(14)8(9)15/h5,7-8,11-12,14-15H,1-4H2/t5-,7-,8+,9-/s2
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3.10E+3n/an/an/an/an/an/an/an/a



Savitribai Phule Pune University (formerly University of Pune)

Curated by ChEMBL


Assay Description
Inhibition of bovine liver beta-galactosidase using 10 mM p-nitrophenyl-beta-D-galactopyranoside as substrate


J Med Chem 58: 7820-32 (2015)

More data for this
Ligand-Target Pair
beta-Galactosidase (β-gal)


(Escherichia coli (Enterobacteria))
BDBM192768
PNG
(β-gal inhibitor, 14)
Show SMILES OC[C@H]1O[C@@H](SCCOCCOC(=O)c2ccc(cc2C(c2ccccc2)c2ccccc2)C(=O)NCCOCCOCCOCCNC(=O)c2ccc(cc2)C(=O)c2ccccc2)[C@H](O)[C@@H](O)[C@H]1O
Show InChI InChI=1/C53H60N2O14S/c56-35-44-47(58)48(59)49(60)53(69-44)70-33-32-67-30-31-68-52(63)42-21-20-41(34-43(42)45(36-10-4-1-5-11-36)37-12-6-2-7-13-37)51(62)55-23-25-65-27-29-66-28-26-64-24-22-54-50(61)40-18-16-39(17-19-40)46(57)38-14-8-3-9-15-38/h1-21,34,44-45,47-49,53,56,58-60H,22-33,35H2,(H,54,61)(H,55,62)/t44-,47+,48+,49-,53+/s2
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3.90E+3n/an/an/an/an/an/an/an/a



Fairfield University



Assay Description
Enzymatic activity of beta-galactosidase from Escherichia coli (1.2 x 10^-10 M) was measured using the colorimetric substrate ortho-nitrophenyl-b-g...


Citation and Details
More data for this
Ligand-Target Pair
Beta-galactosidase


(Bos taurus (Bovine))
BDBM50150471
PNG
(CHEMBL3770764)
KEGG

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4.00E+3n/an/an/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
beta-Galactosidase (β-gal)


(Escherichia coli (Enterobacteria))
BDBM192769
PNG
(β-gal inhibitor, 15)
Show SMILES OC[C@H]1O[C@@H](SCCOCCOCCOCCOC(=O)c2ccc(cc2C(c2ccccc2)c2ccccc2)C(=O)NCCOCCOCCOCCNC(=O)c2ccc(cc2)C(=O)c2ccccc2)[C@H](O)[C@@H](O)[C@H]1O
Show InChI InChI=1/C57H68N2O16S/c60-39-48-51(62)52(63)53(64)57(75-48)76-37-36-73-33-32-71-30-31-72-34-35-74-56(67)46-21-20-45(38-47(46)49(40-10-4-1-5-11-40)41-12-6-2-7-13-41)55(66)59-23-25-69-27-29-70-28-26-68-24-22-58-54(65)44-18-16-43(17-19-44)50(61)42-14-8-3-9-15-42/h1-21,38,48-49,51-53,57,60,62-64H,22-37,39H2,(H,58,65)(H,59,66)/t48-,51+,52+,53-,57+/s2
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5.90E+3n/an/an/an/an/an/an/an/a



Fairfield University



Assay Description
Enzymatic activity of beta-galactosidase from Escherichia coli (1.2 x 10^-10 M) was measured using the colorimetric substrate ortho-nitrophenyl-b-g...


Citation and Details
More data for this
Ligand-Target Pair
Beta-galactosidase


(Homo sapiens)
BDBM50403936
PNG
(CHEMBL2114148)
Show SMILES CCOC(=O)c1cc(oc1C)[C@H]1NC[C@@H](O)[C@H]1O
Show InChI InChI=1S/C12H17NO5/c1-3-17-12(16)7-4-9(18-6(7)2)10-11(15)8(14)5-13-10/h4,8,10-11,13-15H,3,5H2,1-2H3/t8-,10-,11-/m1/s1
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6.40E+3n/an/an/an/an/an/an/an/a



Universidad de Sevilla

Curated by ChEMBL


Assay Description
Inhibition constant of the compound against Beta-galactosidase from Jack beans; Mixed (Non competitive and competitive)


Bioorg Med Chem Lett 12: 2335-9 (2002)

More data for this
Ligand-Target Pair
Beta-galactosidase


(Aspergillus niger)
BDBM50287006
PNG
(Azepane-3,4,5,6-tetraol | CHEMBL13922)
Show SMILES O[C@H]1CNC[C@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C6H13NO4/c8-3-1-7-2-4(9)6(11)5(3)10/h3-11H,1-2H2/t3-,4-,5+,6+/m0/s1
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6.50E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was tested for inhibition of beta-galactosidase from aspergillus niger.


Citation and Details
More data for this
Ligand-Target Pair
Beta-galactosidase


(Homo sapiens)
BDBM50403936
PNG
(CHEMBL2114148)
Show SMILES CCOC(=O)c1cc(oc1C)[C@H]1NC[C@@H](O)[C@H]1O
Show InChI InChI=1S/C12H17NO5/c1-3-17-12(16)7-4-9(18-6(7)2)10-11(15)8(14)5-13-10/h4,8,10-11,13-15H,3,5H2,1-2H3/t8-,10-,11-/m1/s1
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6.60E+3n/an/an/an/an/an/an/an/a



Universidad de Sevilla

Curated by ChEMBL


Assay Description
Inhibition constant of the compound against beta-Galactosidase from Aspergillus orizae; Mixed (Non competitive and competitive)


Bioorg Med Chem Lett 12: 2335-9 (2002)

More data for this
Ligand-Target Pair
Beta-galactosidase


(Homo sapiens)
BDBM50075942
PNG
(CHEMBL165192 | N-[2,5-Dihydroxy-6-hydroxymethyl-4-...)
Show SMILES CC(=O)N[C@H]1C(O)O[C@H](C(O)CO)[C@@H]1C[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O
Show InChI InChI=1S/C15H27NO10/c1-5(19)16-10-6(14(7(20)3-17)26-15(10)24)2-8-11(21)13(23)12(22)9(4-18)25-8/h6-15,17-18,20-24H,2-4H2,1H3,(H,16,19)/t6-,7?,8-,9-,10-,11-,12-,13-,14+,15?/m1/s1
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7.50E+3n/an/an/an/an/an/an/an/a



Institut de chimie organique de l'Université de Lausanne

Curated by ChEMBL


Assay Description
Inhibition constant of the compound against beta-galactosidase enzyme of jack bean was reported


Bioorg Med Chem Lett 9: 793-6 (1999)

More data for this
Ligand-Target Pair
Beta-galactosidase


(Bos taurus (Bovine))
BDBM50150472
PNG
(CHEMBL3770736)
KEGG

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8.94E+3n/an/an/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Beta-galactosidase


(Aspergillus niger)
BDBM50403936
PNG
(CHEMBL2114148)
Show SMILES CCOC(=O)c1cc(oc1C)[C@H]1NC[C@@H](O)[C@H]1O
Show InChI InChI=1S/C12H17NO5/c1-3-17-12(16)7-4-9(18-6(7)2)10-11(15)8(14)5-13-10/h4,8,10-11,13-15H,3,5H2,1-2H3/t8-,10-,11-/m1/s1
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9.80E+3n/an/an/an/an/an/an/an/a



Universidad de Sevilla

Curated by ChEMBL


Assay Description
Inhibition constant (Non competitive) of compound against Beta-galactosidase from Aspergillus niger


Bioorg Med Chem Lett 12: 2335-9 (2002)

More data for this
Ligand-Target Pair
Beta-galactosidase


(Bos taurus (Bovine))
BDBM50350758
PNG
(CHEMBL1818433)
Show SMILES OC[C@H]1CNC[C@@H](O)[C@H]1O
Show InChI InChI=1S/C6H13NO3/c8-3-4-1-7-2-5(9)6(4)10/h4-10H,1-3H2/t4-,5-,6+/m1/s1
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1.00E+4n/an/an/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Beta-galactosidase


(Rhizobium meliloti)
BDBM50163440
PNG
((2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-tr...)
Show SMILES OC[C@H]1NC[C@H](O)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4+,5+,6-/m1/s1
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1.25E+4n/an/an/an/an/an/an/an/a



Technische Universität Graz

Curated by ChEMBL


Assay Description
Inhibition of Agrobacterium sp. beta-galactosidase


Citation and Details
More data for this
Ligand-Target Pair
β-galactosidase


(Bos taurus (Bovine))
BDBM50403937
PNG
(CHEMBL2114149)
Show SMILES CCN(CC)C(=O)c1cc(oc1C)[C@H]1NC[C@@H](O)[C@H]1O
Show InChI InChI=1S/C14H22N2O4/c1-4-16(5-2)14(19)9-6-11(20-8(9)3)12-13(18)10(17)7-15-12/h6,10,12-13,15,17-18H,4-5,7H2,1-3H3/t10-,12-,13-/m1/s1
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1.30E+4n/an/an/an/an/an/an/an/a



Universidad de Sevilla

Curated by ChEMBL


Assay Description
Inhibition constant (Competitive) of the compound against Beta-galactosidase from Bovine liver


Bioorg Med Chem Lett 12: 2335-9 (2002)

More data for this
Ligand-Target Pair
Beta-galactosidase


(Homo sapiens)
BDBM50403937
PNG
(CHEMBL2114149)
Show SMILES CCN(CC)C(=O)c1cc(oc1C)[C@H]1NC[C@@H](O)[C@H]1O
Show InChI InChI=1S/C14H22N2O4/c1-4-16(5-2)14(19)9-6-11(20-8(9)3)12-13(18)10(17)7-15-12/h6,10,12-13,15,17-18H,4-5,7H2,1-3H3/t10-,12-,13-/m1/s1
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1.30E+4n/an/an/an/an/an/an/an/a



Universidad de Sevilla

Curated by ChEMBL


Assay Description
Inhibition constant of the compound against Beta-galactosidase from Aspergillus orizae; Mixed (both competitive and non-competitive)


Bioorg Med Chem Lett 12: 2335-9 (2002)

More data for this
Ligand-Target Pair
Beta-galactosidase


(Aspergillus niger)
BDBM50073992
PNG
(((3aS,4aS,7aS,7bR)-6,6-Dimethyl-3a,4a,7a,7b-tetrah...)
Show SMILES CC1(C)O[C@@H]2O[C@@H]3[C@@H](ON=C3CO)[C@@H]2O1
Show InChI InChI=1S/C9H13NO5/c1-9(2)13-7-6-5(12-8(7)14-9)4(3-11)10-15-6/h5-8,11H,3H2,1-2H3/t5-,6+,7-,8-/m0/s1
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1.80E+4n/an/an/an/an/an/an/an/a



Institut de chimie organique de l'Université de Lausanne

Curated by ChEMBL


Assay Description
Inhibition of beta-galactosidase from Aspergillus niger


Bioorg Med Chem Lett 9: 277-8 (1999)

More data for this
Ligand-Target Pair
β-galactosidase


(Bos taurus (Bovine))
BDBM50353068
PNG
(CHEMBL1822735)
Show SMILES CO[C@@H]1CN(O)C[C@@H](CO)O1
Show InChI InChI=1S/C6H13NO4/c1-10-6-3-7(9)2-5(4-8)11-6/h5-6,8-9H,2-4H2,1H3/t5-,6-/m0/s1
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2.02E+4n/an/an/an/an/an/an/an/a



University of Reading

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney beta-D-galactosidase after 10 to 20 mins


Citation and Details
More data for this
Ligand-Target Pair
β-galactosidase


(Bos taurus (Bovine))
BDBM50104295
PNG
(2-[(2-Hydroxy-1-methyl-2,2-diphenyl-ethylamino)-me...)
Show SMILES CC(NCC1NCC(O)C1O)C(O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C20H26N2O3/c1-14(21-12-17-19(24)18(23)13-22-17)20(25,15-8-4-2-5-9-15)16-10-6-3-7-11-16/h2-11,14,17-19,21-25H,12-13H2,1H3
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2.10E+4n/an/an/an/an/an/an/an/a



Section de Chimie de l'Universit£ de Lausanne

Curated by ChEMBL


Assay Description
Inhibitory activity towards Beta-galactosidase from Bovine liver


Bioorg Med Chem Lett 11: 2489-93 (2001)

More data for this
Ligand-Target Pair
Beta-galactosidase


(Homo sapiens)
BDBM50104296
PNG
(2-(2,2-Dihydroxy-ethyl)-pyrrolidine-3,4-diol | CHE...)
Show SMILES OC(O)CC1NCC(O)C1O
Show InChI InChI=1S/C6H13NO4/c8-4-2-7-3(6(4)11)1-5(9)10/h3-11H,1-2H2
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2.50E+4n/an/an/an/an/an/an/an/a



Section de Chimie de l'Universit£ de Lausanne

Curated by ChEMBL


Assay Description
Inhibitory activity towards Beta-galactosidase from Jack bean


Bioorg Med Chem Lett 11: 2489-93 (2001)

More data for this
Ligand-Target Pair
Beta-galactosidase


(Aspergillus niger)
BDBM50403937
PNG
(CHEMBL2114149)
Show SMILES CCN(CC)C(=O)c1cc(oc1C)[C@H]1NC[C@@H](O)[C@H]1O
Show InChI InChI=1S/C14H22N2O4/c1-4-16(5-2)14(19)9-6-11(20-8(9)3)12-13(18)10(17)7-15-12/h6,10,12-13,15,17-18H,4-5,7H2,1-3H3/t10-,12-,13-/m1/s1
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3.00E+4n/an/an/an/an/an/an/an/a



Universidad de Sevilla

Curated by ChEMBL


Assay Description
Inhibition constant(Non competitive) of compound against Beta-galactosidase from Aspergillus niger


Bioorg Med Chem Lett 12: 2335-9 (2002)

More data for this
Ligand-Target Pair
β-galactosidase


(Bos taurus (Bovine))
BDBM50403936
PNG
(CHEMBL2114148)
Show SMILES CCOC(=O)c1cc(oc1C)[C@H]1NC[C@@H](O)[C@H]1O
Show InChI InChI=1S/C12H17NO5/c1-3-17-12(16)7-4-9(18-6(7)2)10-11(15)8(14)5-13-10/h4,8,10-11,13-15H,3,5H2,1-2H3/t8-,10-,11-/m1/s1
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3.50E+4n/an/an/an/an/an/an/an/a



Universidad de Sevilla

Curated by ChEMBL


Assay Description
Inhibition constant of the compound against Beta-galactosidase from Bovine liver; Mixed(Competitive and Non Competitive)


Bioorg Med Chem Lett 12: 2335-9 (2002)

More data for this
Ligand-Target Pair
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