Compile Data Set for Download or QSAR

Found 36 hits Enz. Inhib. hit(s) with Target = 'Cyclic AMP-dependent protein kinase (PKA)'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclic AMP-dependent protein kinase (PKA) (Oryctolagus cuniculus (Rabbit))	BDBM36603 (4'',6''-Dideoxybalanol, 6) Show SMILES OC(=O)c1cccc(O)c1C(=O)c1ccc(cc1)C(=O)O[C@@H]1CCCNC[C@H]1NC(=O)c1ccc(O)cc1 Show InChI InChI=1S/C28H26N2O8/c31-19-12-10-17(11-13-19)26(34)30-21-15-29-14-2-5-23(21)38-28(37)18-8-6-16(7-9-18)25(33)24-20(27(35)36)3-1-4-22(24)32/h1,3-4,6-13,21,23,29,31-32H,2,5,14-15H2,(H,30,34)(H,35,36)/t21-,23-/m1/s1	PDB MMDB KEGG UniProtKB/TrEMBL GoogleScholar	PC cid PC sid UniChem Similars	Article PubMed	3.40	-49.1	5.5	n/a	n/a	n/a	n/a	7.5	30
University of California San Diego					Assay Description Cyclic AMP-dependent protein kinase (PKA) enzyme inhibition assay using purified recombinant C subunit of PKA (catalytic (C) subunit (cPKA)) with hol...				Chem Biol 2: 601-8 (1995) Article DOI: 10.1016/1074-5521(95)90124-8 BindingDB Entry DOI: 10.7270/Q2HQ3X8D
					More data for this Ligand-Target Pair
Cyclic AMP-dependent protein kinase (PKA) (Oryctolagus cuniculus (Rabbit))	BDBM36604 (5'-Deoxybalanol, 7) Show SMILES OC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)O[C@@H]1CCCNC[C@H]1NC(=O)c1ccccc1 Show InChI InChI=1S/C28H26N2O9/c31-19-9-4-8-17(27(36)37)23(19)25(34)24-20(32)12-16(13-21(24)33)28(38)39-22-10-5-11-29-14-18(22)30-26(35)15-6-2-1-3-7-15/h1-4,6-9,12-13,18,22,29,31-33H,5,10-11,14H2,(H,30,35)(H,36,37)/t18-,22-/m1/s1	PDB MMDB KEGG UniProtKB/TrEMBL GoogleScholar	PC cid PC sid UniChem Patents Similars	Article PubMed	3.5	-49.1	5.70	n/a	n/a	n/a	n/a	7.5	30
University of California San Diego					Assay Description Cyclic AMP-dependent protein kinase (PKA) enzyme inhibition assay using purified recombinant C subunit of PKA (catalytic (C) subunit (cPKA)) with hol...				Chem Biol 2: 601-8 (1995) Article DOI: 10.1016/1074-5521(95)90124-8 BindingDB Entry DOI: 10.7270/Q2HQ3X8D
					More data for this Ligand-Target Pair
Cyclic AMP-dependent protein kinase (PKA) (Oryctolagus cuniculus (Rabbit))	BDBM3207 (10''-Deoxybalanol, 4 | 2-{[2,6-dihydroxy-4-({[(3R,...) Show SMILES OC(=O)c1ccccc1C(=O)c1c(O)cc(cc1O)C(=O)O[C@@H]1CCCNC[C@H]1NC(=O)c1ccc(O)cc1 Show InChI InChI=1S/C28H26N2O9/c31-17-9-7-15(8-10-17)26(35)30-20-14-29-11-3-6-23(20)39-28(38)16-12-21(32)24(22(33)13-16)25(34)18-4-1-2-5-19(18)27(36)37/h1-2,4-5,7-10,12-13,20,23,29,31-33H,3,6,11,14H2,(H,30,35)(H,36,37)/t20-,23-/m1/s1	PDB MMDB KEGG UniProtKB/TrEMBL GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.90	-48.8	6.30	n/a	n/a	n/a	n/a	7.5	30
University of California San Diego					Assay Description Cyclic AMP-dependent protein kinase (PKA) enzyme inhibition assay using purified recombinant C subunit of PKA (catalytic (C) subunit (cPKA)) with hol...				Chem Biol 2: 601-8 (1995) Article DOI: 10.1016/1074-5521(95)90124-8 BindingDB Entry DOI: 10.7270/Q2HQ3X8D
					More data for this Ligand-Target Pair
Cyclic AMP-dependent protein kinase (PKA) (Oryctolagus cuniculus (Rabbit))	BDBM3149 (2-{[2,6-dihydroxy-4-({[(3R,4R)-3-[(4-hydroxybenzen...) Show SMILES OC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)O[C@@H]1CCCNC[C@H]1NC(=O)c1ccc(O)cc1 Show InChI InChI=1S/C28H26N2O10/c31-16-8-6-14(7-9-16)26(36)30-18-13-29-10-2-5-22(18)40-28(39)15-11-20(33)24(21(34)12-15)25(35)23-17(27(37)38)3-1-4-19(23)32/h1,3-4,6-9,11-12,18,22,29,31-34H,2,5,10,13H2,(H,30,36)(H,37,38)/t18-,22-/m1/s1	PDB MMDB KEGG UniProtKB/TrEMBL GoogleScholar	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	4.70	-48.3	n/a	n/a	n/a	n/a	n/a	7.5	30
University of California San Diego					Assay Description Cyclic AMP-dependent protein kinase (PKA) enzyme inhibition assay using purified recombinant C subunit of PKA (catalytic (C) subunit (cPKA)) with hol...				Chem Biol 2: 601-8 (1995) Article DOI: 10.1016/1074-5521(95)90124-8 BindingDB Entry DOI: 10.7270/Q2HQ3X8D
					More data for this Ligand-Target Pair
Cyclic AMP-dependent protein kinase (PKA) (Oryctolagus cuniculus (Rabbit))	BDBM36602 (14''-Decarboxybalanol hydrochloride, 5) Show SMILES Oc1ccc(cc1)C(=O)N[C@@H]1C[NH2+]CCC[C@H]1OC(=O)c1cc(O)c(C(=O)c2ccccc2O)c(O)c1 Show InChI InChI=1S/C27H26N2O8/c30-17-9-7-15(8-10-17)26(35)29-19-14-28-11-3-6-23(19)37-27(36)16-12-21(32)24(22(33)13-16)25(34)18-4-1-2-5-20(18)31/h1-2,4-5,7-10,12-13,19,23,28,30-33H,3,6,11,14H2,(H,29,35)/p+1/t19-,23-/m1/s1	PDB MMDB KEGG UniProtKB/TrEMBL GoogleScholar	PC cid PC sid UniChem Similars	Article PubMed	11	-46.2	18	n/a	n/a	n/a	n/a	7.5	30
University of California San Diego					Assay Description Cyclic AMP-dependent protein kinase (PKA) enzyme inhibition assay using purified recombinant C subunit of PKA (catalytic (C) subunit (cPKA)) with hol...				Chem Biol 2: 601-8 (1995) Article DOI: 10.1016/1074-5521(95)90124-8 BindingDB Entry DOI: 10.7270/Q2HQ3X8D
					More data for this Ligand-Target Pair
Cyclic AMP-dependent protein kinase (PKA) (Oryctolagus cuniculus (Rabbit))	BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) Show SMILES CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 Show InChI InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1	PDB MMDB KEGG UniProtKB/TrEMBL GoogleScholar	Purchase CHEBI CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
University of California San Diego					Assay Description Cyclic AMP-dependent protein kinase (PKA) enzyme inhibition assay using purified recombinant C subunit of PKA (catalytic (C) subunit (cPKA)) with hol...				Chem Biol 2: 601-8 (1995) Article DOI: 10.1016/1074-5521(95)90124-8 BindingDB Entry DOI: 10.7270/Q2HQ3X8D
					More data for this Ligand-Target Pair				3D Structure (crystal)
Cyclic AMP-dependent protein kinase (PKA) (Oryctolagus cuniculus (Rabbit))	BDBM36606 (H-89, 10) Show SMILES Brc1ccc(\C=C\CNCCNOS(=O)c2cccc3cnccc23)cc1 Show InChI InChI=1S/C20H20BrN3O2S/c21-18-8-6-16(7-9-18)3-2-11-22-13-14-24-26-27(25)20-5-1-4-17-15-23-12-10-19(17)20/h1-10,12,15,22,24H,11,13-14H2/b3-2+	PDB MMDB KEGG UniProtKB/TrEMBL GoogleScholar	PC cid PC sid UniChem	Article PubMed	48	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
University of California San Diego					Assay Description Cyclic AMP-dependent protein kinase (PKA) enzyme inhibition assay using purified recombinant C subunit of PKA (catalytic (C) subunit (cPKA)) with hol...				Chem Biol 2: 601-8 (1995) Article DOI: 10.1016/1074-5521(95)90124-8 BindingDB Entry DOI: 10.7270/Q2HQ3X8D
					More data for this Ligand-Target Pair
Cyclic AMP-dependent protein kinase (PKA) (Oryctolagus cuniculus (Rabbit))	BDBM36605 (KT5720, 9) Show SMILES CCCCCCOC(=O)[C@@]1(O)CC2O[C@]1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 Show InChI InChI=1S/C32H31N3O5/c1-3-4-5-10-15-39-30(37)32(38)16-23-34-21-13-8-6-11-18(21)25-26-20(17-33-29(26)36)24-19-12-7-9-14-22(19)35(28(24)27(25)34)31(32,2)40-23/h6-9,11-14,23,38H,3-5,10,15-17H2,1-2H3,(H,33,36)/t23?,31-,32-/m0/s1	PDB MMDB KEGG UniProtKB/TrEMBL GoogleScholar	PC cid PC sid UniChem Similars	Article PubMed	56	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
University of California San Diego					Assay Description Cyclic AMP-dependent protein kinase (PKA) enzyme inhibition assay using purified recombinant C subunit of PKA (catalytic (C) subunit (cPKA)) with hol...				Chem Biol 2: 601-8 (1995) Article DOI: 10.1016/1074-5521(95)90124-8 BindingDB Entry DOI: 10.7270/Q2HQ3X8D
					More data for this Ligand-Target Pair
Cyclic AMP-dependent protein kinase (PKA) (Oryctolagus cuniculus (Rabbit))	BDBM15210 (CHEMBL148333 | H-8 | Lopac-M-9656 | N-(2-methylami...) Show SMILES CNCCNS(=O)(=O)c1cccc2cnccc12 Show InChI InChI=1S/C12H15N3O2S/c1-13-7-8-15-18(16,17)12-4-2-3-10-9-14-6-5-11(10)12/h2-6,9,13,15H,7-8H2,1H3	PDB MMDB KEGG UniProtKB/TrEMBL GoogleScholar	Purchase CHEBI CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biochemistry Curated by ChEMBL					Assay Description Inhibitory constant against cAPK (PKA)				J Biol Chem 271: 26157-64 (1996) Article DOI: 10.1074/jbc.271.42.26157 BindingDB Entry DOI: 10.7270/Q2BR8T3M
					More data for this Ligand-Target Pair				3D Structure (crystal)
Cyclic AMP-dependent protein kinase (PKA) (Oryctolagus cuniculus (Rabbit))	BDBM50366348 (CHEMBL1233654) Show SMILES C[C@H]1CNCCN1S(=O)(=O)c1cccc2cnccc12 Show InChI InChI=1S/C14H17N3O2S/c1-11-9-16-7-8-17(11)20(18,19)14-4-2-3-12-10-15-6-5-13(12)14/h2-6,10-11,16H,7-9H2,1H3/t11-/m0/s1	PDB MMDB KEGG UniProtKB/TrEMBL GoogleScholar	Purchase CHEBI CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biochemistry Curated by ChEMBL					Assay Description Inhibitory constant against cAPK (PKA)				J Biol Chem 271: 26157-64 (1996) Article DOI: 10.1074/jbc.271.42.26157 BindingDB Entry DOI: 10.7270/Q2BR8T3M
					More data for this Ligand-Target Pair				3D Structure (crystal)
Cyclic AMP-dependent protein kinase (PKA) (Oryctolagus cuniculus (Rabbit))	BDBM36600 (Benzophenone fragment, 2) Show SMILES COC(=O)c1cc(O)c(C(=O)c2c(O)cccc2C(O)=O)c(O)c1 Show InChI InChI=1S/C16H12O8/c1-24-16(23)7-5-10(18)13(11(19)6-7)14(20)12-8(15(21)22)3-2-4-9(12)17/h2-6,17-19H,1H3,(H,21,22)	PDB MMDB KEGG UniProtKB/TrEMBL GoogleScholar	Purchase PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	>-29.0	n/a	n/a	n/a	n/a	n/a	7.5	30
University of California San Diego					Assay Description Cyclic AMP-dependent protein kinase (PKA) enzyme inhibition assay using purified recombinant C subunit of PKA (catalytic (C) subunit (cPKA)) with hol...				Chem Biol 2: 601-8 (1995) Article DOI: 10.1016/1074-5521(95)90124-8 BindingDB Entry DOI: 10.7270/Q2HQ3X8D
					More data for this Ligand-Target Pair
Cyclic AMP-dependent protein kinase (PKA) (Oryctolagus cuniculus (Rabbit))	BDBM36601 (Hexahydroazepine, 3) Show SMILES O[C@@H]1CCCNC[C@H]1NC(=O)c1ccc(O)cc1 Show InChI InChI=1S/C13H18N2O3/c16-10-5-3-9(4-6-10)13(18)15-11-8-14-7-1-2-12(11)17/h3-6,11-12,14,16-17H,1-2,7-8H2,(H,15,18)/t11-,12-/m1/s1	PDB MMDB KEGG UniProtKB/TrEMBL GoogleScholar	PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
University of California San Diego					Assay Description Cyclic AMP-dependent protein kinase (PKA) enzyme inhibition assay using purified recombinant C subunit of PKA (catalytic (C) subunit (cPKA)) with hol...				Chem Biol 2: 601-8 (1995) Article DOI: 10.1016/1074-5521(95)90124-8 BindingDB Entry DOI: 10.7270/Q2HQ3X8D
					More data for this Ligand-Target Pair
Cyclic AMP-dependent protein kinase (PKA) (Oryctolagus cuniculus (Rabbit))	BDBM6760 ((+)-K-252a | CHEMBL281948 | K-252a | methyl (15S,1...) Show SMILES COC(=O)[C@@]1(O)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 Show InChI InChI=1S/C27H21N3O5/c1-26-27(33,25(32)34-2)11-18(35-26)29-16-9-5-3-7-13(16)20-21-15(12-28-24(21)31)19-14-8-4-6-10-17(14)30(26)23(19)22(20)29/h3-10,18,33H,11-12H2,1-2H3,(H,28,31)/t18?,26-,27-/m0/s1	PDB MMDB KEGG UniProtKB/TrEMBL GoogleScholar	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	0.0160	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibition of cAMP dependent Protein kinase A of rabbit Skeletal Muscle.				J Med Chem 40: 1863-9 (1997) Article DOI: 10.1021/jm970031d BindingDB Entry DOI: 10.7270/Q2W95891
					More data for this Ligand-Target Pair
Cyclic AMP-dependent protein kinase (PKA) (Oryctolagus cuniculus (Rabbit))	BDBM50058332 (CHEMBL299496 | methyl 10,23-di(ethylsulfanylmethyl...) Show SMILES CCSCc1ccc2n3C4C[C@](O)(C(=O)OC)[C@](C)(O4)n4c5ccc(CSCC)cc5c5c6CNC(=O)c6c(c2c1)c3c45 Show InChI InChI=1S/C33H33N3O5S2/c1-5-42-15-17-7-9-22-19(11-17)26-27-21(14-34-30(27)37)25-20-12-18(16-43-6-2)8-10-23(20)36-29(25)28(26)35(22)24-13-33(39,31(38)40-4)32(36,3)41-24/h7-12,24,39H,5-6,13-16H2,1-4H3,(H,34,37)/t24?,32-,33-/m0/s1	PDB MMDB KEGG UniProtKB/TrEMBL GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>10	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibition of cAMP dependent Protein kinase A of rabbit Skeletal Muscle.				J Med Chem 40: 1863-9 (1997) Article DOI: 10.1021/jm970031d BindingDB Entry DOI: 10.7270/Q2W95891
					More data for this Ligand-Target Pair
Cyclic AMP-dependent protein kinase (PKA) (Oryctolagus cuniculus (Rabbit))	BDBM2672 (3,13,23-triazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^...) Show SMILES O=C1NC(=O)c2c1c1c3ccccc3[nH]c1c1[nH]c3ccccc3c21 Show InChI InChI=1S/C20H11N3O2/c24-19-15-13-9-5-1-3-7-11(9)21-17(13)18-14(16(15)20(25)23-19)10-6-2-4-8-12(10)22-18/h1-8,21-22H,(H,23,24,25)	PDB MMDB KEGG UniProtKB/TrEMBL GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ciba-Geigy Limited Curated by ChEMBL					Assay Description Inhibitory activity was determined against protein kinase A (PKA) of rabbit				J Med Chem 37: 1015-27 (1994) Article DOI: 10.1021/jm00033a019 BindingDB Entry DOI: 10.7270/Q2M32TTP
					More data for this Ligand-Target Pair
Cyclic AMP-dependent protein kinase (PKA) (Oryctolagus cuniculus (Rabbit))	BDBM2583 (3,4-Bis(3-indolyl)-1H-pyrrole-2,5-dione | 3,4-bis(...) Show SMILES O=C1NC(=O)C(=C1c1c[nH]c2ccccc12)c1c[nH]c2ccccc12 Show InChI InChI=1S/C20H13N3O2/c24-19-17(13-9-21-15-7-3-1-5-11(13)15)18(20(25)23-19)14-10-22-16-8-4-2-6-12(14)16/h1-10,21-22H,(H,23,24,25)	PDB MMDB KEGG UniProtKB/TrEMBL GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ciba-Geigy Limited Curated by ChEMBL					Assay Description Inhibitory activity was determined against protein kinase A (PKA) of rabbit				J Med Chem 37: 1015-27 (1994) Article DOI: 10.1021/jm00033a019 BindingDB Entry DOI: 10.7270/Q2M32TTP
					More data for this Ligand-Target Pair
Cyclic AMP-dependent protein kinase (PKA) (Oryctolagus cuniculus (Rabbit))	BDBM50040929 (4,5-dianilinophthalimide | 5,6-bis(phenylamino)-1H...) Show SMILES O=C1NC(=O)c2cc(Nc3ccccc3)c(Nc3ccccc3)cc12 Show InChI InChI=1S/C20H15N3O2/c24-19-15-11-17(21-13-7-3-1-4-8-13)18(12-16(15)20(25)23-19)22-14-9-5-2-6-10-14/h1-12,21-22H,(H,23,24,25)	PDB MMDB KEGG UniProtKB/TrEMBL GoogleScholar	Purchase CHEBI CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ciba-Geigy Limited Curated by ChEMBL					Assay Description Inhibitory activity was determined against protein kinase A (PKA) of rabbit				J Med Chem 37: 1015-27 (1994) Article DOI: 10.1021/jm00033a019 BindingDB Entry DOI: 10.7270/Q2M32TTP
					More data for this Ligand-Target Pair
Cyclic AMP-dependent protein kinase (PKA) (Oryctolagus cuniculus (Rabbit))	BDBM50040927 (CHEMBL268441 | N-(1,3-Dioxo-6-phenylamino-2,3-dihy...) Show SMILES CC(=O)N(c1ccccc1)c1cc2C(=O)NC(=O)c2cc1Nc1ccccc1 Show InChI InChI=1S/C22H17N3O3/c1-14(26)25(16-10-6-3-7-11-16)20-13-18-17(21(27)24-22(18)28)12-19(20)23-15-8-4-2-5-9-15/h2-13,23H,1H3,(H,24,27,28)	PDB MMDB KEGG UniProtKB/TrEMBL GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ciba-Geigy Limited Curated by ChEMBL					Assay Description Inhibitory activity was determined against protein kinase A (PKA) of rabbit				J Med Chem 37: 1015-27 (1994) Article DOI: 10.1021/jm00033a019 BindingDB Entry DOI: 10.7270/Q2M32TTP
					More data for this Ligand-Target Pair
Cyclic AMP-dependent protein kinase (PKA) (Oryctolagus cuniculus (Rabbit))	BDBM50040931 (4,5-Bis-(4-fluoro-phenylamino)-phthalic acid dimet...) Show SMILES COC(=O)c1cc(Nc2ccc(F)cc2)c(Nc2ccc(F)cc2)cc1C(=O)OC Show InChI InChI=1S/C22H18F2N2O4/c1-29-21(27)17-11-19(25-15-7-3-13(23)4-8-15)20(12-18(17)22(28)30-2)26-16-9-5-14(24)6-10-16/h3-12,25-26H,1-2H3	PDB MMDB KEGG UniProtKB/TrEMBL GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ciba-Geigy Limited Curated by ChEMBL					Assay Description Inhibitory activity was determined against protein kinase A (PKA) of rabbit				J Med Chem 37: 1015-27 (1994) Article DOI: 10.1021/jm00033a019 BindingDB Entry DOI: 10.7270/Q2M32TTP
					More data for this Ligand-Target Pair
Cyclic AMP-dependent protein kinase (PKA) (Oryctolagus cuniculus (Rabbit))	BDBM50040917 (5-(Methyl-phenyl-amino)-6-phenylamino-isoindole-1,...) Show SMILES CN(c1ccccc1)c1cc2C(=O)NC(=O)c2cc1Nc1ccccc1 Show InChI InChI=1S/C21H17N3O2/c1-24(15-10-6-3-7-11-15)19-13-17-16(20(25)23-21(17)26)12-18(19)22-14-8-4-2-5-9-14/h2-13,22H,1H3,(H,23,25,26)	PDB MMDB KEGG UniProtKB/TrEMBL GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ciba-Geigy Limited Curated by ChEMBL					Assay Description Inhibitory activity was determined against protein kinase A (PKA) of rabbit				J Med Chem 37: 1015-27 (1994) Article DOI: 10.1021/jm00033a019 BindingDB Entry DOI: 10.7270/Q2M32TTP
					More data for this Ligand-Target Pair
Cyclic AMP-dependent protein kinase (PKA) (Oryctolagus cuniculus (Rabbit))	BDBM50040913 (1,4-Diphenyl-1,2,3,4-tetrahydro-pyrrolo[3,4-g]quin...) Show SMILES O=C1NC(=O)c2cc3N(CCN(c4ccccc4)c3cc12)c1ccccc1 Show InChI InChI=1S/C22H17N3O2/c26-21-17-13-19-20(14-18(17)22(27)23-21)25(16-9-5-2-6-10-16)12-11-24(19)15-7-3-1-4-8-15/h1-10,13-14H,11-12H2,(H,23,26,27)	PDB MMDB KEGG UniProtKB/TrEMBL GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ciba-Geigy Limited Curated by ChEMBL					Assay Description Inhibitory activity was determined against protein kinase A (PKA) of rabbit				J Med Chem 37: 1015-27 (1994) Article DOI: 10.1021/jm00033a019 BindingDB Entry DOI: 10.7270/Q2M32TTP
					More data for this Ligand-Target Pair
Cyclic AMP-dependent protein kinase (PKA) (Oryctolagus cuniculus (Rabbit))	BDBM50040930 (5,6-Bis-(4-fluoro-phenylamino)-isoindole-1,3-dione...) Show SMILES Fc1ccc(Nc2cc3C(=O)NC(=O)c3cc2Nc2ccc(F)cc2)cc1 Show InChI InChI=1S/C20H13F2N3O2/c21-11-1-5-13(6-2-11)23-17-9-15-16(20(27)25-19(15)26)10-18(17)24-14-7-3-12(22)4-8-14/h1-10,23-24H,(H,25,26,27)	PDB MMDB KEGG UniProtKB/TrEMBL GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ciba-Geigy Limited Curated by ChEMBL					Assay Description Inhibitory activity was determined against protein kinase A (PKA) of rabbit				J Med Chem 37: 1015-27 (1994) Article DOI: 10.1021/jm00033a019 BindingDB Entry DOI: 10.7270/Q2M32TTP
					More data for this Ligand-Target Pair
Cyclic AMP-dependent protein kinase (PKA) (Oryctolagus cuniculus (Rabbit))	BDBM50040928 (4-[6-(4-cyanoanilino)-1,3-dioxo-2,3-dihydro-1H-5-i...) Show SMILES O=C1NC(=O)c2cc(Nc3ccc(cc3)C#N)c(Nc3ccc(cc3)C#N)cc12 Show InChI InChI=1S/C22H13N5O2/c23-11-13-1-5-15(6-2-13)25-19-9-17-18(22(29)27-21(17)28)10-20(19)26-16-7-3-14(12-24)4-8-16/h1-10,25-26H,(H,27,28,29)	PDB MMDB KEGG UniProtKB/TrEMBL GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ciba-Geigy Limited Curated by ChEMBL					Assay Description Inhibitory activity was determined against protein kinase A (PKA) of rabbit				J Med Chem 37: 1015-27 (1994) Article DOI: 10.1021/jm00033a019 BindingDB Entry DOI: 10.7270/Q2M32TTP
					More data for this Ligand-Target Pair
Cyclic AMP-dependent protein kinase (PKA) (Oryctolagus cuniculus (Rabbit))	BDBM50040923 (2-Methyl-5,6-bis-phenylamino-isoindole-1,3-dione |...) Show SMILES CN1C(=O)c2cc(Nc3ccccc3)c(Nc3ccccc3)cc2C1=O Show InChI InChI=1S/C21H17N3O2/c1-24-20(25)16-12-18(22-14-8-4-2-5-9-14)19(13-17(16)21(24)26)23-15-10-6-3-7-11-15/h2-13,22-23H,1H3	PDB MMDB KEGG UniProtKB/TrEMBL GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ciba-Geigy Limited Curated by ChEMBL					Assay Description Inhibitory activity was determined against protein kinase A (PKA) of rabbit				J Med Chem 37: 1015-27 (1994) Article DOI: 10.1021/jm00033a019 BindingDB Entry DOI: 10.7270/Q2M32TTP
					More data for this Ligand-Target Pair
Cyclic AMP-dependent protein kinase (PKA) (Oryctolagus cuniculus (Rabbit))	BDBM50040916 (5,6-Bis-(4-hydroxy-phenylamino)-isoindole-1,3-dion...) Show SMILES Oc1ccc(Nc2cc3C(=O)NC(=O)c3cc2Nc2ccc(O)cc2)cc1 Show InChI InChI=1S/C20H15N3O4/c24-13-5-1-11(2-6-13)21-17-9-15-16(20(27)23-19(15)26)10-18(17)22-12-3-7-14(25)8-4-12/h1-10,21-22,24-25H,(H,23,26,27)	PDB MMDB KEGG UniProtKB/TrEMBL GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ciba-Geigy Limited Curated by ChEMBL					Assay Description Inhibitory activity was determined against protein kinase A (PKA) of rabbit				J Med Chem 37: 1015-27 (1994) Article DOI: 10.1021/jm00033a019 BindingDB Entry DOI: 10.7270/Q2M32TTP
					More data for this Ligand-Target Pair
Cyclic AMP-dependent protein kinase (PKA) (Oryctolagus cuniculus (Rabbit))	BDBM50040912 (5,6-Bis-cyclohexylamino-isoindole-1,3-dione | CHEM...) Show SMILES O=C1NC(=O)c2cc(NC3CCCCC3)c(NC3CCCCC3)cc12 Show InChI InChI=1S/C20H27N3O2/c24-19-15-11-17(21-13-7-3-1-4-8-13)18(12-16(15)20(25)23-19)22-14-9-5-2-6-10-14/h11-14,21-22H,1-10H2,(H,23,24,25)	PDB MMDB KEGG UniProtKB/TrEMBL GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ciba-Geigy Limited Curated by ChEMBL					Assay Description Inhibitory activity was determined against protein kinase A (PKA) of rabbit				J Med Chem 37: 1015-27 (1994) Article DOI: 10.1021/jm00033a019 BindingDB Entry DOI: 10.7270/Q2M32TTP
					More data for this Ligand-Target Pair
Cyclic AMP-dependent protein kinase (PKA) (Oryctolagus cuniculus (Rabbit))	BDBM50040922 (2-Phenyl-5,6-bis-phenylamino-isoindole-1,3-dione |...) Show SMILES O=C1N(C(=O)c2cc(Nc3ccccc3)c(Nc3ccccc3)cc12)c1ccccc1 Show InChI InChI=1S/C26H19N3O2/c30-25-21-16-23(27-18-10-4-1-5-11-18)24(28-19-12-6-2-7-13-19)17-22(21)26(31)29(25)20-14-8-3-9-15-20/h1-17,27-28H	PDB MMDB KEGG UniProtKB/TrEMBL GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ciba-Geigy Limited Curated by ChEMBL					Assay Description Inhibitory activity was determined against protein kinase A (PKA) of rabbit				J Med Chem 37: 1015-27 (1994) Article DOI: 10.1021/jm00033a019 BindingDB Entry DOI: 10.7270/Q2M32TTP
					More data for this Ligand-Target Pair
Cyclic AMP-dependent protein kinase (PKA) (Oryctolagus cuniculus (Rabbit))	BDBM50040921 (5,6-Bis-(4-diethylamino-phenylamino)-isoindole-1,3...) Show SMILES CCN(CC)c1ccc(Nc2cc3C(=O)NC(=O)c3cc2Nc2ccc(cc2)N(CC)CC)cc1 Show InChI InChI=1S/C28H33N5O2/c1-5-32(6-2)21-13-9-19(10-14-21)29-25-17-23-24(28(35)31-27(23)34)18-26(25)30-20-11-15-22(16-12-20)33(7-3)8-4/h9-18,29-30H,5-8H2,1-4H3,(H,31,34,35)	PDB MMDB KEGG UniProtKB/TrEMBL GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ciba-Geigy Limited Curated by ChEMBL					Assay Description Inhibitory activity was determined against protein kinase A (PKA) of rabbit				J Med Chem 37: 1015-27 (1994) Article DOI: 10.1021/jm00033a019 BindingDB Entry DOI: 10.7270/Q2M32TTP
					More data for this Ligand-Target Pair
Cyclic AMP-dependent protein kinase (PKA) (Oryctolagus cuniculus (Rabbit))	BDBM50040925 (5,6-Bis-(4-methoxy-phenylamino)-isoindole-1,3-dion...) Show SMILES COc1ccc(Nc2cc3C(=O)NC(=O)c3cc2Nc2ccc(OC)cc2)cc1 Show InChI InChI=1S/C22H19N3O4/c1-28-15-7-3-13(4-8-15)23-19-11-17-18(22(27)25-21(17)26)12-20(19)24-14-5-9-16(29-2)10-6-14/h3-12,23-24H,1-2H3,(H,25,26,27)	PDB MMDB KEGG UniProtKB/TrEMBL GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ciba-Geigy Limited Curated by ChEMBL					Assay Description Inhibitory activity was determined against protein kinase A (PKA) of rabbit				J Med Chem 37: 1015-27 (1994) Article DOI: 10.1021/jm00033a019 BindingDB Entry DOI: 10.7270/Q2M32TTP
					More data for this Ligand-Target Pair
Cyclic AMP-dependent protein kinase (PKA) (Oryctolagus cuniculus (Rabbit))	BDBM50040919 (5,6-Bis-(biphenyl-4-ylamino)-isoindole-1,3-dione |...) Show SMILES O=C1NC(=O)c2cc(Nc3ccc(cc3)-c3ccccc3)c(Nc3ccc(cc3)-c3ccccc3)cc12 Show InChI InChI=1S/C32H23N3O2/c36-31-27-19-29(33-25-15-11-23(12-16-25)21-7-3-1-4-8-21)30(20-28(27)32(37)35-31)34-26-17-13-24(14-18-26)22-9-5-2-6-10-22/h1-20,33-34H,(H,35,36,37)	PDB MMDB KEGG UniProtKB/TrEMBL GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ciba-Geigy Limited Curated by ChEMBL					Assay Description Inhibitory activity was determined against protein kinase A (PKA) of rabbit				J Med Chem 37: 1015-27 (1994) Article DOI: 10.1021/jm00033a019 BindingDB Entry DOI: 10.7270/Q2M32TTP
					More data for this Ligand-Target Pair
Cyclic AMP-dependent protein kinase (PKA) (Oryctolagus cuniculus (Rabbit))	BDBM50040926 (4,5-Bis-phenylamino-phthalic acid dimethyl ester |...) Show SMILES COC(=O)c1cc(Nc2ccccc2)c(Nc2ccccc2)cc1C(=O)OC Show InChI InChI=1S/C22H20N2O4/c1-27-21(25)17-13-19(23-15-9-5-3-6-10-15)20(14-18(17)22(26)28-2)24-16-11-7-4-8-12-16/h3-14,23-24H,1-2H3	PDB MMDB KEGG UniProtKB/TrEMBL GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ciba-Geigy Limited Curated by ChEMBL					Assay Description Inhibitory activity was determined against protein kinase A (PKA) of rabbit				J Med Chem 37: 1015-27 (1994) Article DOI: 10.1021/jm00033a019 BindingDB Entry DOI: 10.7270/Q2M32TTP
					More data for this Ligand-Target Pair
Cyclic AMP-dependent protein kinase (PKA) (Oryctolagus cuniculus (Rabbit))	BDBM50040914 (5-(4-Methoxy-phenylamino)-6-phenylamino-isoindole-...) Show SMILES COc1ccc(Nc2cc3C(=O)NC(=O)c3cc2Nc2ccccc2)cc1 Show InChI InChI=1S/C21H17N3O3/c1-27-15-9-7-14(8-10-15)23-19-12-17-16(20(25)24-21(17)26)11-18(19)22-13-5-3-2-4-6-13/h2-12,22-23H,1H3,(H,24,25,26)	PDB MMDB KEGG UniProtKB/TrEMBL GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ciba-Geigy Limited Curated by ChEMBL					Assay Description Inhibitory activity was determined against protein kinase A (PKA) of rabbit				J Med Chem 37: 1015-27 (1994) Article DOI: 10.1021/jm00033a019 BindingDB Entry DOI: 10.7270/Q2M32TTP
					More data for this Ligand-Target Pair
Cyclic AMP-dependent protein kinase (PKA) (Oryctolagus cuniculus (Rabbit))	BDBM50040918 (5,6-Bis-(methyl-phenyl-amino)-isoindole-1,3-dione ...) Show SMILES CN(c1ccccc1)c1cc2C(=O)NC(=O)c2cc1N(C)c1ccccc1 Show InChI InChI=1S/C22H19N3O2/c1-24(15-9-5-3-6-10-15)19-13-17-18(22(27)23-21(17)26)14-20(19)25(2)16-11-7-4-8-12-16/h3-14H,1-2H3,(H,23,26,27)	PDB MMDB KEGG UniProtKB/TrEMBL GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ciba-Geigy Limited Curated by ChEMBL					Assay Description Inhibitory activity was determined against protein kinase A (PKA) of rabbit				J Med Chem 37: 1015-27 (1994) Article DOI: 10.1021/jm00033a019 BindingDB Entry DOI: 10.7270/Q2M32TTP
					More data for this Ligand-Target Pair
Cyclic AMP-dependent protein kinase (PKA) (Oryctolagus cuniculus (Rabbit))	BDBM50040924 (5,6-Bis-phenylsulfanyl-isoindole-1,3-dione | CHEMB...) Show SMILES O=C1NC(=O)c2cc(Sc3ccccc3)c(Sc3ccccc3)cc12 Show InChI InChI=1S/C20H13NO2S2/c22-19-15-11-17(24-13-7-3-1-4-8-13)18(12-16(15)20(23)21-19)25-14-9-5-2-6-10-14/h1-12H,(H,21,22,23)	PDB MMDB KEGG UniProtKB/TrEMBL GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ciba-Geigy Limited Curated by ChEMBL					Assay Description Inhibitory activity was determined against protein kinase A (PKA) of rabbit				J Med Chem 37: 1015-27 (1994) Article DOI: 10.1021/jm00033a019 BindingDB Entry DOI: 10.7270/Q2M32TTP
					More data for this Ligand-Target Pair
Cyclic AMP-dependent protein kinase (PKA) (Oryctolagus cuniculus (Rabbit))	BDBM50040920 (5,6-Bis-p-tolylamino-isoindole-1,3-dione | CHEMBL7...) Show SMILES Cc1ccc(Nc2cc3C(=O)NC(=O)c3cc2Nc2ccc(C)cc2)cc1 Show InChI InChI=1S/C22H19N3O2/c1-13-3-7-15(8-4-13)23-19-11-17-18(22(27)25-21(17)26)12-20(19)24-16-9-5-14(2)6-10-16/h3-12,23-24H,1-2H3,(H,25,26,27)	PDB MMDB KEGG UniProtKB/TrEMBL GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ciba-Geigy Limited Curated by ChEMBL					Assay Description Inhibitory activity was determined against protein kinase A (PKA) of rabbit				J Med Chem 37: 1015-27 (1994) Article DOI: 10.1021/jm00033a019 BindingDB Entry DOI: 10.7270/Q2M32TTP
					More data for this Ligand-Target Pair
Cyclic AMP-dependent protein kinase (PKA) (Oryctolagus cuniculus (Rabbit))	BDBM50040915 (5,6-Bis-(4-iodo-phenylamino)-isoindole-1,3-dione |...) Show SMILES Ic1ccc(Nc2cc3C(=O)NC(=O)c3cc2Nc2ccc(I)cc2)cc1 Show InChI InChI=1S/C20H13I2N3O2/c21-11-1-5-13(6-2-11)23-17-9-15-16(20(27)25-19(15)26)10-18(17)24-14-7-3-12(22)4-8-14/h1-10,23-24H,(H,25,26,27)	PDB MMDB KEGG UniProtKB/TrEMBL GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ciba-Geigy Limited Curated by ChEMBL					Assay Description Inhibitory activity was determined against protein kinase A (PKA) of rabbit				J Med Chem 37: 1015-27 (1994) Article DOI: 10.1021/jm00033a019 BindingDB Entry DOI: 10.7270/Q2M32TTP
					More data for this Ligand-Target Pair