BindingDB PrimarySearch

Found 10298 hits Enz. Inhib. hit(s) with Target = 'Monoamine oxidase'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50430726 (CHEMBL2333930) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.129	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human MAOB				J Med Chem 58: 6717-32 (2015) Article DOI: 10.1021/jm501690r BindingDB Entry DOI: 10.7270/Q2VT1TWM
Sapienza Universit£ di Roma Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50334292 (5-(4-Phenylbutyl)isatin \| CHEMBL1642678) Show SMILES O=C1Nc2ccc(CCCCc3ccccc3)cc2C1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.280	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
North-West University Curated by ChEMBL					Assay Description Inhibition of human recombinant MAOB expressed in insect cells by fluorescence assay				Bioorg Med Chem 19: 261-74 (2011) Article DOI: 10.1016/j.bmc.2010.11.028 BindingDB Entry DOI: 10.7270/Q2DR2VSB
North-West University Curated by ChEMBL					More data for this Ligand-Target Pair
Monoamine oxidase (Rattus norvegicus (rat))	BDBM50087809 (CHEMBL298006 \| Methyl-(1-methyl-1H-indol-2-ylmethy...) Show SMILES CN(CC#C)Cc1cc2ccccc2n1C Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universitat Autònoma de Barcelona Curated by ChEMBL					Assay Description Inhibitory activity against Monoamine oxidase A				J Med Chem 43: 1684-91 (2000) Article DOI: 10.1021/jm991164x BindingDB Entry DOI: 10.7270/Q2C53K38
Universitat Autònoma de Barcelona Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50341160 (3-(anthracen-9-yl)-5-(3-nitrophenyl)-4,5-dihydro-1...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Birla Institute of Technology Curated by ChEMBL					Assay Description Competitive inhibition of human recombinant MAO-B after 60 mins using p-tyramine as substrate by spectrophotometry				Bioorg Med Chem Lett 21: 1969-73 (2011) Article DOI: 10.1016/j.bmcl.2011.02.030 BindingDB Entry DOI: 10.7270/Q2JM29XC
Birla Institute of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Rattus norvegicus (rat))	BDBM50341160 (3-(anthracen-9-yl)-5-(3-nitrophenyl)-4,5-dihydro-1...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Birla Institute of Technology Curated by ChEMBL					Assay Description Competitive inhibition of rat liver MAO-B after 60 mins using p-tyramine as substrate by spectrophotometry				Bioorg Med Chem Lett 21: 1969-73 (2011) Article DOI: 10.1016/j.bmcl.2011.02.030 BindingDB Entry DOI: 10.7270/Q2JM29XC
Birla Institute of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Rattus norvegicus (rat))	BDBM50341161 (3-(anthracen-9-yl)-5-(4-methoxyphenyl)-4,5-dihydro...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Birla Institute of Technology Curated by ChEMBL					Assay Description Competitive inhibition of rat liver MAO-B after 60 mins using p-tyramine as substrate by spectrophotometry				Bioorg Med Chem Lett 21: 1969-73 (2011) Article DOI: 10.1016/j.bmcl.2011.02.030 BindingDB Entry DOI: 10.7270/Q2JM29XC
Birla Institute of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Monoamine oxidase (Bos taurus)	BDBM50361606 (CHEMBL1939851) Show SMILES CCn1ccc(c1)N1C[C@H](COC)OC1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of bovine brain MAOA using kynuramine as a substrate after 30 mins by spectrofluorometric method				J Med Chem 54: 8228-32 (2011) Article DOI: 10.1021/jm201011x BindingDB Entry DOI: 10.7270/Q2GX4C1S
Sapienza Universit£ di Roma Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50172755 (1,4-diphenyl-(1E,3E)-1,3-butadiene \| CHEMBL198810) Show SMILES C(\C=C\c1ccccc1)=C/c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human MAOB				J Med Chem 58: 6717-32 (2015) Article DOI: 10.1021/jm501690r BindingDB Entry DOI: 10.7270/Q2VT1TWM
Sapienza Universit£ di Roma Curated by ChEMBL					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Rattus norvegicus (rat))	BDBM50087800 ((5-Benzyloxy-1H-indol-2-ylmethyl)-prop-2-ynyl-amin...) Show SMILES C#CCNCc1cc2cc(OCc3ccccc3)ccc2[nH]1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.75	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universitat Autònoma de Barcelona Curated by ChEMBL					Assay Description Inhibitory activity against Monoamine oxidase B				J Med Chem 43: 1684-91 (2000) Article DOI: 10.1021/jm991164x BindingDB Entry DOI: 10.7270/Q2C53K38
Universitat Autònoma de Barcelona Curated by ChEMBL					More data for this Ligand-Target Pair
Monoamine oxidase (Bos taurus)	BDBM50361609 (CHEMBL1939853) Show SMILES CCn1ccc(c1)N1C[C@H](CN=[N+]=[N-])OC1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of bovine brain MAOA using kynuramine as a substrate after 30 mins by spectrofluorometric method				J Med Chem 54: 8228-32 (2011) Article DOI: 10.1021/jm201011x BindingDB Entry DOI: 10.7270/Q2GX4C1S
Sapienza Universit£ di Roma Curated by ChEMBL					More data for this Ligand-Target Pair
Monoamine oxidase (Rattus norvegicus (rat))	BDBM50087796 ((5-Methoxy-1-methyl-1H-indol-2-ylmethyl)-prop-2-yn...) Show SMILES COc1ccc2n(C)c(CNCC#C)cc2c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universitat Autònoma de Barcelona Curated by ChEMBL					Assay Description Inhibitory activity against Monoamine oxidase A				J Med Chem 43: 1684-91 (2000) Article DOI: 10.1021/jm991164x BindingDB Entry DOI: 10.7270/Q2C53K38
Universitat Autònoma de Barcelona Curated by ChEMBL					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Rattus norvegicus (rat))	BDBM50304157 (3-(2-Thienyl)-2-thiocarbamoyl-2,3,4,5,6,7-hexahydr...) Show SMILES NC(=S)N1N=C2CCCCC2C1c1cccs1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hacettepe University Curated by ChEMBL					Assay Description Competitive inhibition of MAOB in rat liver homogenate by spectrophotometrically				Bioorg Med Chem 17: 6761-72 (2009) Article DOI: 10.1016/j.bmc.2009.07.033 BindingDB Entry DOI: 10.7270/Q2TQ61M2
Hacettepe University Curated by ChEMBL					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Rattus norvegicus (rat))	BDBM50304152 (3-(2-Furyl)-2-thiocarbamoyl-2,3,4,5,6,7-hexahydro-...) Show SMILES NC(=S)N1N=C2CCCCC2C1c1ccco1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.960	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hacettepe University Curated by ChEMBL					Assay Description Competitive inhibition of MAOB in rat liver homogenate by spectrophotometrically				Bioorg Med Chem 17: 6761-72 (2009) Article DOI: 10.1016/j.bmc.2009.07.033 BindingDB Entry DOI: 10.7270/Q2TQ61M2
Hacettepe University Curated by ChEMBL					More data for this Ligand-Target Pair
Monoamine oxidase (Bos taurus)	BDBM50273595 (CHEMBL462097 \| N-(1H-Indol-2-ylmethyl)-N-methyl-N-...) Show SMILES CN(CCc1ccccc1)Cc1cc2ccccc2[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Università di Roma Curated by ChEMBL					Assay Description Inhibition of bovine brain mitochondrial MAO-A by fluorometric assay				Bioorg Med Chem 16: 9729-40 (2008) Article DOI: 10.1016/j.bmc.2008.09.072 BindingDB Entry DOI: 10.7270/Q20001ZK
Sapienza Università di Roma Curated by ChEMBL					More data for this Ligand-Target Pair
Monoamine oxidase (Bos taurus)	BDBM50361607 (CHEMBL1938411) Show SMILES COC[C@H]1CN(C(=O)O1)c1ccn(CC=C)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of bovine brain MAOA using kynuramine as a substrate after 30 mins by spectrofluorometric method				J Med Chem 54: 8228-32 (2011) Article DOI: 10.1021/jm201011x BindingDB Entry DOI: 10.7270/Q2GX4C1S
Sapienza Universit£ di Roma Curated by ChEMBL					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Bos taurus)	BDBM11014 ((-)-(S)1 \| (5S)-5-(4-chlorophenyl)-3-(4-methylphen...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	1	-53.6	n/a	n/a	n/a	n/a	n/a	7.4	38
Universita degli Studi di Roma La Sapienza					Assay Description MAO A and MAO B activities were determined spectrophotometrically using kynuramine as substrates. Fluorimetric measurements were recorded with a Perk...				J Med Chem 48: 7113-22 (2005) Article DOI: 10.1021/jm040903t BindingDB Entry DOI: 10.7270/Q2JH3JDW
Universita degli Studi di Roma La Sapienza					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50341152 (3-(anthracen-9-yl)-5-(4-nitrophenyl)-4,5-dihydro-1...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Birla Institute of Technology Curated by ChEMBL					Assay Description Competitive inhibition of human recombinant MAO-B after 60 mins using p-tyramine as substrate by spectrophotometry				Bioorg Med Chem Lett 21: 1969-73 (2011) Article DOI: 10.1016/j.bmcl.2011.02.030 BindingDB Entry DOI: 10.7270/Q2JM29XC
Birla Institute of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Monoamine oxidase (Rattus norvegicus (rat))	BDBM50087791 (But-2-ynyl-(5-methoxy-1-methyl-1H-indol-2-ylmethyl...) Show SMILES COc1ccc2n(C)c(CN(C)CC#CC)cc2c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universitat Autònoma de Barcelona Curated by ChEMBL					Assay Description Inhibitory activity against Monoamine oxidase A				J Med Chem 43: 1684-91 (2000) Article DOI: 10.1021/jm991164x BindingDB Entry DOI: 10.7270/Q2C53K38
Universitat Autònoma de Barcelona Curated by ChEMBL					More data for this Ligand-Target Pair
Monoamine oxidase (Rattus norvegicus (rat))	BDBM50087801 ((5-Methoxy-1-methyl-1H-indol-2-ylmethyl)-methyl-pr...) Show SMILES COc1ccc2n(C)c(CN(C)CC#C)cc2c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universitat Autònoma de Barcelona Curated by ChEMBL					Assay Description Inhibitory activity against Monoamine oxidase A				J Med Chem 43: 1684-91 (2000) Article DOI: 10.1021/jm991164x BindingDB Entry DOI: 10.7270/Q2C53K38
Universitat Autònoma de Barcelona Curated by ChEMBL					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Bos taurus)	BDBM11004 (1-thiocarbamoyl-3,5-diaryl-4,5-dihydro-(1H)-pyrazo...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	1.5	-52.6	n/a	n/a	n/a	n/a	n/a	7.4	38
Universita degli Studi di Roma La Sapienza					Assay Description MAO A and MAO B activities were determined spectrophotometrically using kynuramine as substrates. Fluorimetric measurements were recorded with a Perk...				J Med Chem 48: 7113-22 (2005) Article DOI: 10.1021/jm040903t BindingDB Entry DOI: 10.7270/Q2JH3JDW
Universita degli Studi di Roma La Sapienza					More data for this Ligand-Target Pair
Monoamine oxidase (Bos taurus)	BDBM50273561 (CHEMBL459336 \| N-Methyl,N-(3-phenylpropyl)-1-methy...) Show SMILES CN(CCCc1ccccc1)C(=O)c1cc2ccccc2n1C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Università di Roma Curated by ChEMBL					Assay Description Inhibition of bovine brain mitochondrial MAO-B by fluorometric assay				Bioorg Med Chem 16: 9729-40 (2008) Article DOI: 10.1016/j.bmc.2008.09.072 BindingDB Entry DOI: 10.7270/Q20001ZK
Sapienza Università di Roma Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50341161 (3-(anthracen-9-yl)-5-(4-methoxyphenyl)-4,5-dihydro...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Birla Institute of Technology Curated by ChEMBL					Assay Description Competitive inhibition of human recombinant MAO-B after 60 mins using p-tyramine as substrate by spectrophotometry				Bioorg Med Chem Lett 21: 1969-73 (2011) Article DOI: 10.1016/j.bmcl.2011.02.030 BindingDB Entry DOI: 10.7270/Q2JM29XC
Birla Institute of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Monoamine Oxidase Type A (MAO-A) (Bos taurus)	BDBM15604 ((R)-N-(alpha-Cyclohexylethyl),N-methyl-1H-pyrrole-...) Show SMILES C[C@H](C1CCCCC1)N(C)C(=O)c1ccc[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita di Roma La Sapienza					Assay Description MAO A and MAO B activities were determined spectrophotometrically using kinuramine as substrates. Fluorimetric measurements were recorded with a Perk...				J Med Chem 50: 922-31 (2007) Article DOI: 10.1021/jm060882y BindingDB Entry DOI: 10.7270/Q2GH9G61
Universita di Roma La Sapienza					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50341154 (3-(anthracen-9-yl)-5-(4-chlorophenyl)-4,5-dihydro-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Birla Institute of Technology Curated by ChEMBL					Assay Description Competitive inhibition of human recombinant MAO-B after 60 mins using p-tyramine as substrate by spectrophotometry				Bioorg Med Chem Lett 21: 1969-73 (2011) Article DOI: 10.1016/j.bmcl.2011.02.030 BindingDB Entry DOI: 10.7270/Q2JM29XC
Birla Institute of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM50292171 (1-[3-(4-Hydroxy-phenyl)-5-(2-methoxy-phenyl)-4,5-d...) Show SMILES COc1ccccc1C1CC(=NN1C(C)=O)c1ccc(O)cc1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Binding affinity was evaluated against human monoamino oxidase A				J Med Chem 47: 2071-4 (2004) Article DOI: 10.1021/jm031042b BindingDB Entry DOI: 10.7270/Q28053BQ
					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Rattus norvegicus (rat))	BDBM50341154 (3-(anthracen-9-yl)-5-(4-chlorophenyl)-4,5-dihydro-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Birla Institute of Technology Curated by ChEMBL					Assay Description Competitive inhibition of rat liver MAO-B after 60 mins using p-tyramine as substrate by spectrophotometry				Bioorg Med Chem Lett 21: 1969-73 (2011) Article DOI: 10.1016/j.bmcl.2011.02.030 BindingDB Entry DOI: 10.7270/Q2JM29XC
Birla Institute of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Rattus norvegicus (rat))	BDBM50341152 (3-(anthracen-9-yl)-5-(4-nitrophenyl)-4,5-dihydro-1...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Birla Institute of Technology Curated by ChEMBL					Assay Description Competitive inhibition of rat liver MAO-B after 60 mins using p-tyramine as substrate by spectrophotometry				Bioorg Med Chem Lett 21: 1969-73 (2011) Article DOI: 10.1016/j.bmcl.2011.02.030 BindingDB Entry DOI: 10.7270/Q2JM29XC
Birla Institute of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Monoamine oxidase (Bos taurus)	BDBM50110715 (5-Methoxymethyl-3-[4-(4,4,4-trifluoro-3-hydroxy-bu...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of bovine brain mitochondrial Monoamine oxidase A (MAO-A) compared to toloxatone				J Med Chem 45: 1180-3 (2002) Article DOI: 10.1021/jm015578d BindingDB Entry DOI: 10.7270/Q28W3F11
					More data for this Ligand-Target Pair
Monoamine oxidase (Bos taurus)	BDBM50361617 (BEFLOXATONE) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of bovine brain MAOA using kynuramine as a substrate after 30 mins by spectrofluorometric method				J Med Chem 54: 8228-32 (2011) Article DOI: 10.1021/jm201011x BindingDB Entry DOI: 10.7270/Q2GX4C1S
Sapienza Universit£ di Roma Curated by ChEMBL					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Bos taurus)	BDBM11015 ((+)-(R)1 \| (5R)-5-(4-chlorophenyl)-3-(4-methylphen...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	2.70	-51.0	n/a	n/a	n/a	n/a	n/a	7.4	38
Universita degli Studi di Roma La Sapienza					Assay Description MAO A and MAO B activities were determined spectrophotometrically using kynuramine as substrates. Fluorimetric measurements were recorded with a Perk...				J Med Chem 48: 7113-22 (2005) Article DOI: 10.1021/jm040903t BindingDB Entry DOI: 10.7270/Q2JH3JDW
Universita degli Studi di Roma La Sapienza					More data for this Ligand-Target Pair
Monoamine oxidase (Bos taurus)	BDBM50361603 (CHEMBL1939848) Show SMILES CCn1ccc(c1)N1C[C@H](CO)OC1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of bovine brain MAOA using kynuramine as a substrate after 30 mins by spectrofluorometric method				J Med Chem 54: 8228-32 (2011) Article DOI: 10.1021/jm201011x BindingDB Entry DOI: 10.7270/Q2GX4C1S
Sapienza Universit£ di Roma Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50350637 (CHEMBL1813523) Show SMILES Brc1ccc(COc2ccc3C(=O)NC(=O)c3c2)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
North-West University Curated by ChEMBL					Assay Description Inhibition of human recombinant MAOB expressed in insect cells using kynuramine substrate using Cheng and Prusoff equation by fluorescence spectrosco...				Bioorg Med Chem 19: 4829-40 (2011) Article DOI: 10.1016/j.bmc.2011.06.070 BindingDB Entry DOI: 10.7270/Q2H41RTW
North-West University Curated by ChEMBL					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Rattus norvegicus (rat))	BDBM50087809 (CHEMBL298006 \| Methyl-(1-methyl-1H-indol-2-ylmethy...) Show SMILES CN(CC#C)Cc1cc2ccccc2n1C Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universitat Autònoma de Barcelona Curated by ChEMBL					Assay Description Inhibitory activity against Monoamine oxidase B				J Med Chem 43: 1684-91 (2000) Article DOI: 10.1021/jm991164x BindingDB Entry DOI: 10.7270/Q2C53K38
Universitat Autònoma de Barcelona Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM15579 (CHEMBL972 \| DEPRENYL \| L-Deprenyl \| N-methyl-N-[(2...) Show SMILES C[C@H](Cc1ccccc1)N(C)CC#C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dart NeuroScience, LLC Curated by ChEMBL					Assay Description Inhibition of human recombinant soluble MAO-B expressed in Pichia pastoris incubated for 30 mins prior to substrate addition measured after 60 mins b...				Bioorg Med Chem 23: 770-8 (2015) Article DOI: 10.1016/j.bmc.2014.12.063 BindingDB Entry DOI: 10.7270/Q2J38V8K
Dart NeuroScience, LLC Curated by ChEMBL					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Rattus norvegicus (rat))	BDBM50341156 (3-(anthracen-9-yl)-5-phenyl-4,5-dihydro-1H-pyrazol...) Show SMILES C1C(N=NC1c1c2ccccc2cc2ccccc12)c1ccccc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.43	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Birla Institute of Technology Curated by ChEMBL					Assay Description Competitive inhibition of rat liver MAO-B after 60 mins using p-tyramine as substrate by spectrophotometry				Bioorg Med Chem Lett 21: 1969-73 (2011) Article DOI: 10.1016/j.bmcl.2011.02.030 BindingDB Entry DOI: 10.7270/Q2JM29XC
Birla Institute of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Monoamine oxidase (Bos taurus)	BDBM50273486 (CHEMBL464597 \| N-Methyl,N-phenyl-1H-indole-2-carbo...) Show SMILES CN(C(=O)c1cc2ccccc2[nH]1)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Università di Roma Curated by ChEMBL					Assay Description Inhibition of bovine brain mitochondrial MAO-A by fluorometric assay				Bioorg Med Chem 16: 9729-40 (2008) Article DOI: 10.1016/j.bmc.2008.09.072 BindingDB Entry DOI: 10.7270/Q20001ZK
Sapienza Università di Roma Curated by ChEMBL					More data for this Ligand-Target Pair
Monoamine oxidase (Rattus norvegicus (rat))	BDBM50168981 (1-(1-Methyl-1H-pyrrol-2-yl)-2-phenyl-2-pyrrolidin-...) Show SMILES Cn1cccc1C(=O)[C@H](N1CCCC1)c1ccccc1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibtory concentration for rat Monoamine oxidase A				J Med Chem 48: 4220-3 (2005) Article DOI: 10.1021/jm050172c BindingDB Entry DOI: 10.7270/Q2862FZV
Università di Roma La Sapienza Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50145630 (CHEMBL3764447) Show SMILES Clc1ccc(COc2ccc3sc(=O)oc3c2)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
North-West University Curated by ChEMBL					Assay Description Competition inhibition of recombinant human MAO-B pretreated with compound for 15 mins followed by addition of 50 uM kynuramine as substrate by Linew...				Bioorg Med Chem Lett 26: 1200-4 (2016) Article DOI: 10.1016/j.bmcl.2016.01.034 BindingDB Entry DOI: 10.7270/Q2154JWF
North-West University Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50341155 (3-(anthracen-9-yl)-5-p-tolyl-4,5-dihydro-1H-pyrazo...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.56	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Birla Institute of Technology Curated by ChEMBL					Assay Description Competitive inhibition of human recombinant MAO-B after 60 mins using p-tyramine as substrate by spectrophotometry				Bioorg Med Chem Lett 21: 1969-73 (2011) Article DOI: 10.1016/j.bmcl.2011.02.030 BindingDB Entry DOI: 10.7270/Q2JM29XC
Birla Institute of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM50333418 (7-(4,4,4-Trifluorobutoxy)-1-methyl-beta-carboline ...) Show SMILES Cc1nccc2c3ccc(OCCCC(F)(F)F)cc3[nH]c12 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Facult£s Universitaires Notre-Dame de la Paix Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-A expressed in baculovirus-infected Bacillus thuringiensis israelensis cells after 1 hr by two-step bioluminescen...				Bioorg Med Chem 19: 134-44 (2011) Article DOI: 10.1016/j.bmc.2010.11.041 BindingDB Entry DOI: 10.7270/Q2NK3F9X
					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Rattus norvegicus (rat))	BDBM50341155 (3-(anthracen-9-yl)-5-p-tolyl-4,5-dihydro-1H-pyrazo...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Birla Institute of Technology Curated by ChEMBL					Assay Description Competitive inhibition of rat liver MAO-B after 60 mins using p-tyramine as substrate by spectrophotometry				Bioorg Med Chem Lett 21: 1969-73 (2011) Article DOI: 10.1016/j.bmcl.2011.02.030 BindingDB Entry DOI: 10.7270/Q2JM29XC
Birla Institute of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM15579 (CHEMBL972 \| DEPRENYL \| L-Deprenyl \| N-methyl-N-[(2...) Show SMILES C[C@H](Cc1ccccc1)N(C)CC#C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dart NeuroScience, LLC Curated by ChEMBL					Assay Description Inhibition of human recombinant microsomal MAO-B expressed in Pichia pastoris incubated for 30 mins prior to substrate addition measured after 60 min...				Bioorg Med Chem 23: 770-8 (2015) Article DOI: 10.1016/j.bmc.2014.12.063 BindingDB Entry DOI: 10.7270/Q2J38V8K
Dart NeuroScience, LLC Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50029816 (5-Chloro-pyridine-2-carboxylic acid (2-amino-ethyl...) Show SMILES NCCNC(=O)c1ccc(Cl)cn1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dart NeuroScience, LLC Curated by ChEMBL					Assay Description Inhibition of human recombinant soluble MAO-B expressed in Pichia pastoris incubated for 30 mins prior to substrate addition measured after 60 mins b...				Bioorg Med Chem 23: 770-8 (2015) Article DOI: 10.1016/j.bmc.2014.12.063 BindingDB Entry DOI: 10.7270/Q2J38V8K
Dart NeuroScience, LLC Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50145630 (CHEMBL3764447) Show SMILES Clc1ccc(COc2ccc3sc(=O)oc3c2)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
North-West University Curated by ChEMBL					Assay Description Inhibition of recombinant human MAO-B pretreated with compound for 15 mins followed by addition of 50 uM kynuramine as substrate by Michaelis-Menten ...				Bioorg Med Chem Lett 26: 1200-4 (2016) Article DOI: 10.1016/j.bmcl.2016.01.034 BindingDB Entry DOI: 10.7270/Q2154JWF
North-West University Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM50333415 (7-(Isobutyloxy)-1-methyl-beta-carboline \| CHEMBL16...) Show SMILES CC(C)COc1ccc2c(c1)[nH]c1c(C)nccc21 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Facult£s Universitaires Notre-Dame de la Paix Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-A expressed in baculovirus-infected Bacillus thuringiensis israelensis cells after 1 hr by two-step bioluminescen...				Bioorg Med Chem 19: 134-44 (2011) Article DOI: 10.1016/j.bmc.2010.11.041 BindingDB Entry DOI: 10.7270/Q2NK3F9X
					More data for this Ligand-Target Pair
Monoamine Oxidase Type A (MAO-A) (Bos taurus)	BDBM11006 (1-thiocarbamoyl-3,5-diaryl-4,5-dihydro-(1H)-pyrazo...) Show SMILES Cc1ccc(cc1)C1=NN(C(C1)c1ccco1)C(N)=S Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	4	-50.0	n/a	n/a	n/a	n/a	n/a	7.4	38
Universita degli Studi di Roma La Sapienza					Assay Description MAO A and MAO B activities were determined spectrophotometrically using kynuramine as substrates. Fluorimetric measurements were recorded with a Perk...				J Med Chem 48: 7113-22 (2005) Article DOI: 10.1021/jm040903t BindingDB Entry DOI: 10.7270/Q2JH3JDW
Universita degli Studi di Roma La Sapienza					More data for this Ligand-Target Pair
Monoamine oxidase (Rattus norvegicus (rat))	BDBM50049679 (6-(4,5-Dihydro-1H-imidazol-2-yl)-2-ethyl-10,10-dio...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wellcome Research Laboratories Curated by ChEMBL					Assay Description Ex vivo value for inhibition of MAO A of rats sacrificed 2 hr after po administration				J Med Chem 39: 1857-63 (1996) Article DOI: 10.1021/jm950595m BindingDB Entry DOI: 10.7270/Q2TM796B
Wellcome Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Rattus norvegicus (rat))	BDBM50087796 ((5-Methoxy-1-methyl-1H-indol-2-ylmethyl)-prop-2-yn...) Show SMILES COc1ccc2n(C)c(CNCC#C)cc2c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universitat Autònoma de Barcelona Curated by ChEMBL					Assay Description Inhibitory activity against Monoamine oxidase B				J Med Chem 43: 1684-91 (2000) Article DOI: 10.1021/jm991164x BindingDB Entry DOI: 10.7270/Q2C53K38
Universitat Autònoma de Barcelona Curated by ChEMBL					More data for this Ligand-Target Pair
Monoamine oxidase (Bos taurus)	BDBM50273528 (CHEMBL460608 \| N-Methyl,N-(2-phenylethyl)-1H-indol...) Show SMILES CN(CCc1ccccc1)C(=O)c1cc2ccccc2[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Università di Roma Curated by ChEMBL					Assay Description Inhibition of bovine brain mitochondrial MAO-A by fluorometric assay				Bioorg Med Chem 16: 9729-40 (2008) Article DOI: 10.1016/j.bmc.2008.09.072 BindingDB Entry DOI: 10.7270/Q20001ZK
Sapienza Università di Roma Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50259619 ((E)-5-Styrylisatin \| CHEMBL466872) Show SMILES O=C1Nc2ccc(\C=C\c3ccccc3)cc2C1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
North-West University Curated by ChEMBL					Assay Description Inhibition of human recombinant MAOB expressed in insect cells by fluorescence assay				Bioorg Med Chem 19: 261-74 (2011) Article DOI: 10.1016/j.bmc.2010.11.028 BindingDB Entry DOI: 10.7270/Q2DR2VSB
North-West University Curated by ChEMBL					More data for this Ligand-Target Pair

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